Variant ID: 7-72982874-C-T

NM_012453.2(TBL2):c.*1963G>A

This variant was identified in 149 publications




Publications:


Genetics of Hypertriglyceridemia.

Frontiers In Endocrinology
JS Dron, RA Hegele
Publication Date: 2020

Variant appearance in text: rs17145738
PubMed Link: 32793115
Variant Present in the following documents:
  • Main text
View BVdb publication page



Relationship between ethanol consumption and TBL2 rs17145738 on LDL-C concentration in Japanese adults: a four season 3-day weighed diet record study.

Bmc Nutrition
S Akimoto, C Goto, K Kuriki
Publication Date: 2019

Variant appearance in text: rs17145738
PubMed Link: 32153974
Variant Present in the following documents:
  • Main text
View BVdb publication page



Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses.

Gastroenterology
N Murphy, R Carreras-Torres, M Song, AT Chan, RM Martin, N Papadimitriou, N Dimou, KK Tsilidis, B Banbury, KE Bradbury, J Besevic, S Rinaldi, E Riboli, AJ Cross, RC Travis, C Agnoli, D Albanes, SI Berndt, S Bézieau, DT Bishop, H Brenner, DD Buchanan, NC Onland-Moret, A Burnett-Hartman, PT Campbell, G Casey, S Castellví-Bel, J Chang-Claude, MD Chirlaque, A de la Chapelle, D English, JC Figueiredo, SJ Gallinger, GG Giles, SB Gruber, A Gsur, J Hampe, H Hampel, TA Harrison, M Hoffmeister, L Hsu, WY Huang, JR Huyghe, MA Jenkins, TO Keku, T Kühn, SS Kweon, L Le Marchand, CI Li, L Li, A Lindblom, V Martín, RL Milne, V Moreno, PA Newcomb, K Offit, S Ogino, J Ose, V Perduca, AI Phipps, EA Platz, JD Potter, C Qu, G Rennert, LC Sakoda, C Schafmayer, RE Schoen, ML Slattery, CM Tangen, CM Ulrich, FJB van Duijnhoven, B Van Guelpen, K Visvanathan, P Vodicka, L Vodickova, V Vymetalkova, H Wang, E White, A Wolk, MO Woods, AH Wu, W Zheng, U Peters, MJ Gunter
Publication Date: 2020-04

Variant appearance in text: rs17145738
PubMed Link: 31884074
Variant Present in the following documents:
  • Main text
View BVdb publication page



Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration.

Nature Communications
R Noordam, MM Bos, H Wang, TW Winkler, AR Bentley, TO Kilpeläinen, PS de Vries, YJ Sung, K Schwander, BE Cade, A Manning, H Aschard, MR Brown, H Chen, N Franceschini, SK Musani, M Richard, D Vojinovic, S Aslibekyan, TM Bartz, L de Las Fuentes, M Feitosa, AR Horimoto, M Ilkov, M Kho, A Kraja, C Li, E Lim, Y Liu, DO Mook-Kanamori, T Rankinen, SM Tajuddin, A van der Spek, Z Wang, J Marten, V Laville, M Alver, E Evangelou, ME Graff, M He, B Kühnel, LP Lyytikäinen, P Marques-Vidal, IM Nolte, ND Palmer, R Rauramaa, XO Shu, H Snieder, S Weiss, W Wen, LR Yanek, C Adolfo, C Ballantyne, L Bielak, NR Biermasz, E Boerwinkle, N Dimou, G Eiriksdottir, C Gao, SA Gharib, DJ Gottlieb, J Haba-Rubio, TB Harris, S Heikkinen, R Heinzer, JE Hixson, G Homuth, MA Ikram, P Komulainen, JE Krieger, J Lee, J Liu, KK Lohman, AI Luik, R Mägi, LW Martin, T Meitinger, A Metspalu, Y Milaneschi, MA Nalls, J O'Connell, A Peters, P Peyser, OT Raitakari, AP Reiner, PCN Rensen, TK Rice, SS Rich, T Roenneberg, JI Rotter, PJ Schreiner, J Shikany, SS Sidney, M Sims, CM Sitlani, T Sofer, K Strauch, MA Swertz, KD Taylor, AG Uitterlinden, CM van Duijn, H Völzke, M Waldenberger, RB Wallance, KW van Dijk, C Yu, AB Zonderman, DM Becker, P Elliott, T Esko, C Gieger, HJ Grabe, TA Lakka, T Lehtimäki, KE North, BWJH Penninx, P Vollenweider, LE Wagenknecht, T Wu, YB Xiang, W Zheng, DK Arnett, C Bouchard, MK Evans, V Gudnason, S Kardia, TN Kelly, SB Kritchevsky, RJF Loos, AC Pereira, M Province, BM Psaty, C Rotimi, X Zhu, N Amin, LA Cupples, M Fornage, EF Fox, X Guo, WJ Gauderman, K Rice, C Kooperberg, PB Munroe, CT Liu, AC Morrison, DC Rao, D van Heemst, S Redline
Publication Date: 2019-11-12

Variant appearance in text: rs17145738
PubMed Link: 31719535
Variant Present in the following documents:
  • 41467_2019_12958_MOESM7_ESM.xlsx
View BVdb publication page



Bayesian multivariate reanalysis of large genetic studies identifies many new associations.

Plos Genetics
MC Turchin, M Stephens
Publication Date: 2019-10

Variant appearance in text: rs17145738
PubMed Link: 31596850
Variant Present in the following documents:
  • pgen.1008431.s006.xls
  • pgen.1008431.s007.xls
View BVdb publication page



Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids.

The Journals Of Gerontology. Series A, Biological Sciences And Medical Sciences
AM Kulminski, Y Loika, A Nazarian, I Culminskaya
Publication Date: 2020-09-25

Variant appearance in text: rs17145738
PubMed Link: 31566214
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic architecture of human plasma lipidome and its link to cardiovascular disease.

Nature Communications
R Tabassum, JT Rämö, P Ripatti, JT Koskela, M Kurki, J Karjalainen, P Palta, S Hassan, J Nunez-Fontarnau, TTJ Kiiskinen, S Söderlund, N Matikainen, MJ Gerl, MA Surma, C Klose, NO Stitziel, H Laivuori, AS Havulinna, SK Service, V Salomaa, M Pirinen, , M Jauhiainen, MJ Daly, NB Freimer, A Palotie, MR Taskinen, K Simons, S Ripatti
Publication Date: 2019-09-24

Variant appearance in text: rs17145738
PubMed Link: 31551469
Variant Present in the following documents:
  • 41467_2019_11954_MOESM13_ESM.xlsx
  • 41467_2019_11954_MOESM14_ESM.xlsx
View BVdb publication page



Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans.

Nature Metabolism
KM Garske, DZ Pan, Z Miao, YV Bhagat, C Comenho, CR Robles, JN Benhammou, M Alvarez, A Ko, CJ Ye, JR Pisegna, KL Mohlke, JS Sinsheimer, M Laakso, P Pajukanta
Publication Date: 2019-06

Variant appearance in text: rs17145738
PubMed Link: 31538139
Variant Present in the following documents:
  • Main text
  • nihms-1528316.pdf
  • NIHMS1528316-supplement-Supplementary_Information.pdf
View BVdb publication page



Association between the XKR6 rs7819412 SNP and serum lipid levels and the risk of coronary artery disease and ischemic stroke.

Bmc Cardiovascular Disorders
PF Zheng, RX Yin, GX Deng, YZ Guan, BL Wei, CX Liu
Publication Date: 2019-08-20

Variant appearance in text: rs17145738
PubMed Link: 31429711
Variant Present in the following documents:
  • 12872_2019_Article_1179.pdf
View BVdb publication page



GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits.

Nature Communications
R Pazoki, E Evangelou, D Mosen-Ansorena, RC Pinto, I Karaman, P Blakeley, D Gill, V Zuber, P Elliott, I Tzoulaki, A Dehghan
Publication Date: 2019-08-13

Variant appearance in text: rs17145738
PubMed Link: 31409800
Variant Present in the following documents:
  • 41467_2019_11451_MOESM15_ESM.xlsx
  • 41467_2019_11451_MOESM19_ESM.xlsx
  • 41467_2019_11451_MOESM3_ESM.xlsx
  • 41467_2019_11451_MOESM5_ESM.xlsx
  • 41467_2019_11451_MOESM9_ESM.xlsx
View BVdb publication page



Discovery of Allele-Specific Protein-RNA Interactions in Human Transcriptomes.

American Journal Of Human Genetics
E Bahrami-Samani, Y Xing
Publication Date: 2019-03-07

Variant appearance in text: rs17145738
PubMed Link: 30827501
Variant Present in the following documents:
  • mmc7.xlsx
View BVdb publication page



Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.

Nature Genetics
AE Justice, T Karaderi, HM Highland, KL Young, M Graff, Y Lu, V Turcot, PL Auer, RS Fine, X Guo, C Schurmann, A Lempradl, E Marouli, A Mahajan, TW Winkler, AE Locke, C Medina-Gomez, T Esko, S Vedantam, A Giri, KS Lo, T Alfred, P Mudgal, MCY Ng, NL Heard-Costa, MF Feitosa, AK Manning, SM Willems, S Sivapalaratnam, G Abecasis, DS Alam, M Allison, P Amouyel, Z Arzumanyan, B Balkau, L Bastarache, S Bergmann, LF Bielak, M Blüher, M Boehnke, H Boeing, E Boerwinkle, CA Böger, J Bork-Jensen, EP Bottinger, DW Bowden, I Brandslund, L Broer, AA Burt, AS Butterworth, MJ Caulfield, G Cesana, JC Chambers, DI Chasman, YI Chen, R Chowdhury, C Christensen, AY Chu, FS Collins, JP Cook, AJ Cox, DS Crosslin, J Danesh, PIW de Bakker, S Denus, R Mutsert, G Dedoussis, EW Demerath, JG Dennis, JC Denny, E Di Angelantonio, M Dörr, F Drenos, MP Dubé, AM Dunning, DF Easton, P Elliott, E Evangelou, AE Farmaki, S Feng, E Ferrannini, J Ferrieres, JC Florez, M Fornage, CS Fox, PW Franks, N Friedrich, W Gan, I Gandin, P Gasparini, V Giedraitis, G Girotto, M Gorski, H Grallert, N Grarup, ML Grove, S Gustafsson, J Haessler, T Hansen, AT Hattersley, C Hayward, IM Heid, OL Holmen, GK Hovingh, JMM Howson, Y Hu, YJ Hung, K Hveem, MA Ikram, E Ingelsson, AU Jackson, GP Jarvik, Y Jia, T Jørgensen, P Jousilahti, JM Justesen, B Kahali, M Karaleftheri, SLR Kardia, F Karpe, F Kee, H Kitajima, P Komulainen, JS Kooner, P Kovacs, BK Krämer, K Kuulasmaa, J Kuusisto, M Laakso, TA Lakka, D Lamparter, LA Lange, C Langenberg, EB Larson, NR Lee, WJ Lee, T Lehtimäki, CE Lewis, H Li, J Li, R Li-Gao, LA Lin, X Lin, L Lind, J Lindström, A Linneberg, CT Liu, DJ Liu, J Luan, LP Lyytikäinen, S MacGregor, R Mägi, S Männistö, G Marenne, J Marten, NGD Masca, MI McCarthy, K Meidtner, E Mihailov, L Moilanen, M Moitry, DO Mook-Kanamori, A Morgan, AP Morris, M Müller-Nurasyid, PB Munroe, N Narisu, CP Nelson, M Neville, I Ntalla, JR O'Connell, KR Owen, O Pedersen, GM Peloso, CE Pennell, M Perola, JA Perry, JRB Perry, TH Pers, A Ewing, O Polasek, OT Raitakari, A Rasheed, CK Raulerson, R Rauramaa, DF Reilly, AP Reiner, PM Ridker, MA Rivas, NR Robertson, A Robino, I Rudan, KS Ruth, D Saleheen, V Salomaa, NJ Samani, PJ Schreiner, MB Schulze, RA Scott, M Segura-Lepe, X Sim, AJ Slater, KS Small, BH Smith, JA Smith, L Southam, TD Spector, EK Speliotes, K Stefansson, V Steinthorsdottir, KE Stirrups, K Strauch, HM Stringham, M Stumvoll, L Sun, P Surendran, KMA Swart, JC Tardif, KD Taylor, A Teumer, DJ Thompson, G Thorleifsson, U Thorsteinsdottir, BH Thuesen, A Tönjes, M Torres, E Tsafantakis, J Tuomilehto, AG Uitterlinden, M Uusitupa, CM van Duijn, M Vanhala, R Varma, SH Vermeulen, H Vestergaard, V Vitart, TF Vogt, D Vuckovic, LE Wagenknecht, M Walker, L Wallentin, F Wang, CA Wang, S Wang, NJ Wareham, HR Warren, DM Waterworth, J Wessel, HD White, CJ Willer, JG Wilson, AR Wood, Y Wu, H Yaghootkar, J Yao, LM Yerges-Armstrong, R Young, E Zeggini, X Zhan, W Zhang, JH Zhao, W Zhao, H Zheng, W Zhou, MC Zillikens, F Rivadeneira, IB Borecki, JA Pospisilik, P Deloukas, TM Frayling, G Lettre, KL Mohlke, JI Rotter, Z Kutalik, JN Hirschhorn, LA Cupples, RJF Loos, KE North, CM Lindgren, , , , , , , , , ,
Publication Date: 2019-03

Variant appearance in text: rs17145738
PubMed Link: 30778226
Variant Present in the following documents:
  • NIHMS1016010-supplement-SupplementaryData12.xlsx
View BVdb publication page



Gene-Based Elevated Triglycerides and Type 2 Diabetes Mellitus Risk in the Women's Genome Health Study.

Arteriosclerosis, Thrombosis, And Vascular Biology
S Ahmad, S Mora, PM Ridker, FB Hu, DI Chasman
Publication Date: 2019-01

Variant appearance in text: rs17145738
PubMed Link: 30565958
Variant Present in the following documents:
  • Main text
  • nihms-1512616.pdf
  • NIHMS1512616-supplement-Supplemental_Material.pdf
View BVdb publication page



Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.

Nature Communications
E Ferkingstad, A Oddsson, S Gretarsdottir, S Benonisdottir, G Thorleifsson, AM Deaton, S Jonsson, OA Stefansson, GL Norddahl, F Zink, GA Arnadottir, B Gunnarsson, GH Halldorsson, A Helgadottir, BO Jensson, RP Kristjansson, G Sveinbjornsson, DA Sverrisson, G Masson, I Olafsson, GI Eyjolfsson, O Sigurdardottir, H Holm, I Jonsdottir, S Olafsson, T Steingrimsdottir, T Rafnar, ES Bjornsson, U Thorsteinsdottir, DF Gudbjartsson, P Sulem, K Stefansson
Publication Date: 2018-11-30

Variant appearance in text: rs17145738
PubMed Link: 30504769
Variant Present in the following documents:
  • 41467_2018_7460_MOESM12_ESM.xlsx
View BVdb publication page



Risk of Neuropsychiatric Adverse Effects of Lipid-Lowering Drugs: A Mendelian Randomization Study.

The International Journal Of Neuropsychopharmacology
J Alghamdi, S Matou-Nasri, F Alghamdi, S Alghamdi, M Alfadhel, S Padmanabhan
Publication Date: 2018-12-01

Variant appearance in text: rs17145738
PubMed Link: 29986042
Variant Present in the following documents:
  • pyy060_suppl_supplementary_tables.xlsx
View BVdb publication page



Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.

Nature Communications
SM Zekavat, S Ruotsalainen, RE Handsaker, M Alver, J Bloom, T Poterba, C Seed, J Ernst, M Chaffin, J Engreitz, GM Peloso, A Manichaikul, C Yang, KA Ryan, M Fu, WC Johnson, M Tsai, M Budoff, RS Vasan, LA Cupples, JI Rotter, SS Rich, W Post, BD Mitchell, A Correa, A Metspalu, JG Wilson, V Salomaa, M Kellis, MJ Daly, BM Neale, S McCarroll, I Surakka, T Esko, A Ganna, S Ripatti, S Kathiresan, P Natarajan,
Publication Date: 2018-07-04

Variant appearance in text: rs17145738
PubMed Link: 29973585
Variant Present in the following documents:
  • 41467_2018_4668_MOESM10_ESM.xlsx
  • 41467_2018_4668_MOESM11_ESM.xlsx
  • 41467_2018_4668_MOESM12_ESM.xlsx
  • 41467_2018_4668_MOESM13_ESM.xlsx
  • 41467_2018_4668_MOESM14_ESM.xlsx
  • 41467_2018_4668_MOESM15_ESM.xlsx
  • 41467_2018_4668_MOESM16_ESM.xlsx
  • 41467_2018_4668_MOESM18_ESM.xlsx
  • 41467_2018_4668_MOESM9_ESM.xlsx
View BVdb publication page



Lipid regulatory genes polymorphism in children with and without obesity and cardiometabolic risk factors: The CASPIAN-III study.

Journal Of Research In Medical Sciences : The Official Journal Of Isfahan University Of Medical Sciences
S Hovsepian, SH Javanmard, M Mansourian, M Hashemipour, M Tajadini, R Kelishadi
Publication Date: 2018

Variant appearance in text: rs17145738
PubMed Link: 29531563
Variant Present in the following documents:
  • Main text
View BVdb publication page



Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Nature Genetics
R Malik, G Chauhan, M Traylor, M Sargurupremraj, Y Okada, A Mishra, L Rutten-Jacobs, AK Giese, SW van der Laan, S Gretarsdottir, CD Anderson, M Chong, HHH Adams, T Ago, P Almgren, P Amouyel, H Ay, TM Bartz, OR Benavente, S Bevan, GB Boncoraglio, RD Brown, AS Butterworth, C Carrera, CL Carty, DI Chasman, WM Chen, JW Cole, A Correa, I Cotlarciuc, C Cruchaga, J Danesh, PIW de Bakker, AL DeStefano, M den Hoed, Q Duan, ST Engelter, GJ Falcone, RF Gottesman, RP Grewal, V Gudnason, S Gustafsson, J Haessler, TB Harris, A Hassan, AS Havulinna, SR Heckbert, EG Holliday, G Howard, FC Hsu, HI Hyacinth, MA Ikram, E Ingelsson, MR Irvin, X Jian, J Jiménez-Conde, JA Johnson, JW Jukema, M Kanai, KL Keene, BM Kissela, DO Kleindorfer, C Kooperberg, M Kubo, LA Lange, CD Langefeld, C Langenberg, LJ Launer, JM Lee, R Lemmens, D Leys, CM Lewis, WY Lin, AG Lindgren, E Lorentzen, PK Magnusson, J Maguire, A Manichaikul, PF McArdle, JF Meschia, BD Mitchell, TH Mosley, MA Nalls, T Ninomiya, MJ O'Donnell, BM Psaty, SL Pulit, K Rannikmäe, AP Reiner, KM Rexrode, K Rice, SS Rich, PM Ridker, NS Rost, PM Rothwell, JI Rotter, T Rundek, RL Sacco, S Sakaue, MM Sale, V Salomaa, BR Sapkota, R Schmidt, CO Schmidt, U Schminke, P Sharma, A Slowik, CLM Sudlow, C Tanislav, T Tatlisumak, KD Taylor, VNS Thijs, G Thorleifsson, U Thorsteinsdottir, S Tiedt, S Trompet, C Tzourio, CM van Duijn, M Walters, NJ Wareham, S Wassertheil-Smoller, JG Wilson, KL Wiggins, Q Yang, S Yusuf, , , , , , JC Bis, T Pastinen, A Ruusalepp, EE Schadt, S Koplev, JLM Björkegren, V Codoni, M Civelek, NL Smith, DA Trégouët, IE Christophersen, C Roselli, SA Lubitz, PT Ellinor, ES Tai, JS Kooner, N Kato, J He, P van der Harst, P Elliott, JC Chambers, F Takeuchi, AD Johnson, , , , , , , , , , , DK Sanghera, O Melander, C Jern, D Strbian, I Fernandez-Cadenas, WT Longstreth, A Rolfs, J Hata, D Woo, J Rosand, G Pare, JC Hopewell, D Saleheen, K Stefansson, BB Worrall, SJ Kittner, S Seshadri, M Fornage, HS Markus, JMM Howson, Y Kamatani, S Debette, M Dichgans
Publication Date: 2018-04

Variant appearance in text: rs17145738
PubMed Link: 29531354
Variant Present in the following documents:
  • NIHMS959658-supplement-Supplementary_Table_27.xlsx
View BVdb publication page



Influence of obesity-related risk factors in the aetiology of glioma.

British Journal Of Cancer
L Disney-Hogg, A Sud, PJ Law, AJ Cornish, B Kinnersley, QT Ostrom, K Labreche, JE Eckel-Passow, GN Armstrong, EB Claus, D Il'yasova, J Schildkraut, JS Barnholtz-Sloan, SH Olson, JL Bernstein, RK Lai, AJ Swerdlow, M Simon, P Hoffmann, MM Nöthen, KH Jöckel, S Chanock, P Rajaraman, C Johansen, RB Jenkins, BS Melin, MR Wrensch, M Sanson, ML Bondy, RS Houlston
Publication Date: 2018-04

Variant appearance in text: rs17145738
PubMed Link: 29531326
Variant Present in the following documents:
  • 41416_2018_9_MOESM1_ESM.docx
  • 41416_2018_9_MOESM2_ESM.xlsx
View BVdb publication page



Gene-based association study for lipid traits in diverse cohorts implicates BACE1 and SIDT2 regulation in triglyceride levels.

Peerj
A Andaleon, LS Mogil, HE Wheeler
Publication Date: 2018

Variant appearance in text: rs17145738
PubMed Link: 29404214
Variant Present in the following documents:
  • peerj-06-4314-s001.xlsx
View BVdb publication page



Interactions between Genetics and Sugar-Sweetened Beverage Consumption on Health Outcomes: A Review of Gene-Diet Interaction Studies.

Frontiers In Endocrinology
DE Haslam, NM McKeown, MA Herman, AH Lichtenstein, HS Dashti
Publication Date: 2017

Variant appearance in text: rs17145738
PubMed Link: 29375475
Variant Present in the following documents:
  • Main text
View BVdb publication page



Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.

Plos Genetics
JP Davis, JR Huyghe, AE Locke, AU Jackson, X Sim, HM Stringham, TM Teslovich, RP Welch, C Fuchsberger, N Narisu, PS Chines, AJ Kangas, P Soininen, M Ala-Korpela, J Kuusisto, FS Collins, M Laakso, M Boehnke, KL Mohlke
Publication Date: 2017-10

Variant appearance in text: rs17145738
PubMed Link: 29084231
Variant Present in the following documents:
  • pgen.1007079.s010.xlsx
View BVdb publication page



Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.

Nature Genetics
X Lu, GM Peloso, DJ Liu, Y Wu, H Zhang, W Zhou, J Li, CS Tang, R Dorajoo, H Li, J Long, X Guo, M Xu, CN Spracklen, Y Chen, X Liu, Y Zhang, CC Khor, J Liu, L Sun, L Wang, YT Gao, Y Hu, K Yu, Y Wang, CYY Cheung, F Wang, J Huang, Q Fan, Q Cai, S Chen, J Shi, X Yang, W Zhao, WH Sheu, SS Cherny, M He, AB Feranil, LS Adair, P Gordon-Larsen, S Du, R Varma, YI Chen, XO Shu, KSL Lam, TY Wong, SK Ganesh, Z Mo, K Hveem, LG Fritsche, JB Nielsen, HF Tse, Y Huo, CY Cheng, YE Chen, W Zheng, ES Tai, W Gao, X Lin, W Huang, G Abecasis, , S Kathiresan, KL Mohlke, T Wu, PC Sham, D Gu, CJ Willer
Publication Date: 2017-12

Variant appearance in text: rs17145738
PubMed Link: 29083407
Variant Present in the following documents:
  • NIHMS909133-supplement-1.docx
  • NIHMS909133-supplement-2.xlsx
View BVdb publication page



Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study.

Diabetes
L Sobrin, YH Chong, Q Fan, A Gan, LK Stanwyck, G Kaidonis, JE Craig, J Kim, WL Liao, YC Huang, WJ Lee, YJ Hung, X Guo, Y Hai, E Ipp, S Pollack, H Hancock, A Price, A Penman, P Mitchell, G Liew, AV Smith, V Gudnason, G Tan, BEK Klein, J Kuo, X Li, MW Christiansen, BM Psaty, K Sandow, , RA Jensen, R Klein, MF Cotch, JJ Wang, Y Jia, CJ Chen, YI Chen, JI Rotter, FJ Tsai, CL Hanis, KP Burdon, TY Wong, CY Cheng
Publication Date: 2017-12

Variant appearance in text: rs17145738
PubMed Link: 28951389
Variant Present in the following documents:
  • Main text
  • DB170398SupplementaryData.pdf
View BVdb publication page



HDL-cholesterol concentration in pregnant Chinese Han women of late second trimester associated with genetic variants in CETP, ABCA1, APOC3, and GALNT2.

Oncotarget
M Cui, W Li, L Ma, F Ping, J Liu, X Wu, J Mao, X Wang, M Nie
Publication Date: 2017-08-22

Variant appearance in text: rs17145738
PubMed Link: 28915626
Variant Present in the following documents:
  • Main text
View BVdb publication page



Evaluating the Causal Relation of ApoA-IV with Disease-Related Traits - A Bidirectional Two-sample Mendelian Randomization Study.

Scientific Reports
S Mack, S Coassin, J Vaucher, F Kronenberg, C Lamina,
Publication Date: 2017-08-18

Variant appearance in text: rs17145738
PubMed Link: 28821713
Variant Present in the following documents:
  • 41598_2017_7213_MOESM1_ESM.pdf
View BVdb publication page



Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.

Lipids In Health And Disease
CS Paththinige, ND Sirisena, V Dissanayake
Publication Date: 2017-06-02

Variant appearance in text: rs17145738
PubMed Link: 28577571
Variant Present in the following documents:
  • 12944_2017_488_MOESM1_ESM.xlsx
  • aaaaaMain text
View BVdb publication page



Common and rare genetic markers of lipid variation in subjects with type 2 diabetes from the ACCORD clinical trial.

Peerj
SW Marvel, DM Rotroff, MJ Wagner, JB Buse, TM Havener, HL McLeod, AA Motsinger-Reif,
Publication Date: 2017

Variant appearance in text: rs17145738
PubMed Link: 28480134
Variant Present in the following documents:
  • peerj-05-3187-s002.xlsx
View BVdb publication page



Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

Plos Genetics
M Graff, RA Scott, AE Justice, KL Young, MF Feitosa, L Barata, TW Winkler, AY Chu, A Mahajan, D Hadley, L Xue, T Workalemahu, NL Heard-Costa, M den Hoed, TS Ahluwalia, Q Qi, JS Ngwa, F Renström, L Quaye, JD Eicher, JE Hayes, M Cornelis, Z Kutalik, E Lim, J Luan, JE Huffman, W Zhang, W Zhao, PJ Griffin, T Haller, S Ahmad, PM Marques-Vidal, S Bien, L Yengo, A Teumer, AV Smith, M Kumari, MN Harder, JM Justesen, ME Kleber, M Hollensted, K Lohman, NV Rivera, JB Whitfield, JH Zhao, HM Stringham, LP Lyytikäinen, C Huppertz, G Willemsen, WJ Peyrot, Y Wu, K Kristiansson, A Demirkan, M Fornage, M Hassinen, LF Bielak, G Cadby, T Tanaka, R Mägi, PJ van der Most, AU Jackson, JL Bragg-Gresham, V Vitart, J Marten, P Navarro, C Bellis, D Pasko, Å Johansson, S Snitker, YC Cheng, J Eriksson, U Lim, M Aadahl, LS Adair, N Amin, B Balkau, J Auvinen, J Beilby, RN Bergman, S Bergmann, AG Bertoni, J Blangero, A Bonnefond, LL Bonnycastle, JB Borja, S Brage, F Busonero, S Buyske, H Campbell, PS Chines, FS Collins, T Corre, GD Smith, GE Delgado, N Dueker, M Dörr, T Ebeling, G Eiriksdottir, T Esko, JD Faul, M Fu, K Færch, C Gieger, S Gläser, J Gong, P Gordon-Larsen, H Grallert, TB Grammer, N Grarup, G van Grootheest, K Harald, ND Hastie, AS Havulinna, D Hernandez, L Hindorff, LJ Hocking, OL Holmens, C Holzapfel, JJ Hottenga, J Huang, T Huang, J Hui, C Huth, N Hutri-Kähönen, AL James, JO Jansson, MA Jhun, M Juonala, L Kinnunen, HA Koistinen, I Kolcic, P Komulainen, J Kuusisto, K Kvaløy, M Kähönen, TA Lakka, LJ Launer, B Lehne, CM Lindgren, M Lorentzon, R Luben, M Marre, Y Milaneschi, KL Monda, GW Montgomery, MHM De Moor, A Mulas, M Müller-Nurasyid, AW Musk, R Männikkö, S Männistö, N Narisu, M Nauck, JA Nettleton, IM Nolte, AJ Oldehinkel, M Olden, KK Ong, S Padmanabhan, L Paternoster, J Perez, M Perola, A Peters, U Peters, PA Peyser, I Prokopenko, H Puolijoki, OT Raitakari, T Rankinen, LJ Rasmussen-Torvik, R Rawal, PM Ridker, LM Rose, I Rudan, C Sarti, MA Sarzynski, K Savonen, WR Scott, S Sanna, AR Shuldiner, S Sidney, G Silbernagel, BH Smith, JA Smith, H Snieder, A Stančáková, B Sternfeld, AJ Swift, T Tammelin, ST Tan, B Thorand, D Thuillier, L Vandenput, H Vestergaard, JV van Vliet-Ostaptchouk, MC Vohl, U Völker, G Waeber, M Walker, S Wild, A Wong, AF Wright, MC Zillikens, N Zubair, CA Haiman, L Lemarchand, U Gyllensten, C Ohlsson, A Hofman, F Rivadeneira, AG Uitterlinden, L Pérusse, JF Wilson, C Hayward, O Polasek, F Cucca, K Hveem, CA Hartman, A Tönjes, S Bandinelli, LJ Palmer, SLR Kardia, R Rauramaa, TIA Sørensen, J Tuomilehto, V Salomaa, BWJH Penninx, EJC de Geus, DI Boomsma, T Lehtimäki, M Mangino, M Laakso, C Bouchard, NG Martin, D Kuh, Y Liu, A Linneberg, W März, K Strauch, M Kivimäki, TB Harris, V Gudnason, H Völzke, L Qi, MR Järvelin, JC Chambers, JS Kooner, P Froguel, C Kooperberg, P Vollenweider, G Hallmans, T Hansen, O Pedersen, A Metspalu, NJ Wareham, C Langenberg, DR Weir, DJ Porteous, E Boerwinkle, DI Chasman, , , , GR Abecasis, I Barroso, MI McCarthy, TM Frayling, JR O'Connell, CM van Duijn, M Boehnke, IM Heid, KL Mohlke, DP Strachan, CS Fox, CT Liu, JN Hirschhorn, RJ Klein, AD Johnson, IB Borecki, PW Franks, KE North, LA Cupples, RJF Loos, TO Kilpeläinen
Publication Date: 2017-04

Variant appearance in text: rs17145738
PubMed Link: 28448500
Variant Present in the following documents:
  • pgen.1006528.s019.xlsx
View BVdb publication page



Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci.

Human Molecular Genetics
N Zubair, M Graff, J Luis Ambite, WS Bush, G Kichaev, Y Lu, A Manichaikul, WH Sheu, D Absher, TL Assimes, SJ Bielinski, EP Bottinger, P Buzkova, LM Chuang, RH Chung, B Cochran, L Dumitrescu, O Gottesman, JW Haessler, C Haiman, G Heiss, CA Hsiung, YJ Hung, CM Hwu, JJ Juang, L Le Marchand, IT Lee, WJ Lee, LA Lin, D Lin, SY Lin, RH Mackey, LW Martin, B Pasaniuc, U Peters, I Predazzi, T Quertermous, AP Reiner, J Robinson, JI Rotter, KK Ryckman, PJ Schreiner, E Stahl, R Tao, MY Tsai, LL Waite, TD Wang, S Buyske, YD Ida Chen, I Cheng, DC Crawford, RJF Loos, SS Rich, M Fornage, KE North, C Kooperberg, CL Carty
Publication Date: 2016-12-15

Variant appearance in text: rs17145738
PubMed Link: 28426890
Variant Present in the following documents:
  • Main text
  • ddw358_supp.docx
View BVdb publication page



Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.

Journal Of Cellular And Molecular Medicine
Y Zhu, D Zhang, D Zhou, Z Li, Z Li, L Fang, M Yang, Z Shan, H Li, J Chen, X Zhou, W Ye, S Yu, H Li, L Cai, C Liu, J Zhang, L Wang, Y Lai, L Ruan, Z Sun, S Zhang, H Wang, Y Liu, Y Xu, J Ling, C Xu, Y Zhang, D Lv, Z Yuan, J Zhang, Y Zhang, Y Shi, M Lai
Publication Date: 2017-06

Variant appearance in text: rs17145738
PubMed Link: 28371326
Variant Present in the following documents:
  • JCMM-21-1106-s002.xlsx
View BVdb publication page



Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer.

International Journal Of Cancer
H Rodriguez-Broadbent, PJ Law, A Sud, K Palin, S Tuupanen, A Gylfe, UA Hänninen, T Cajuso, T Tanskanen, J Kondelin, E Kaasinen, AP Sarin, S Ripatti, JG Eriksson, H Rissanen, P Knekt, E Pukkala, P Jousilahti, V Salomaa, A Palotie, L Renkonen-Sinisalo, A Lepistö, J Böhm, JP Mecklin, NA Al-Tassan, C Palles, L Martin, E Barclay, SM Farrington, MN Timofeeva, BF Meyer, SM Wakil, H Campbell, CG Smith, S Idziaszczyk, TS Maughan, R Kaplan, R Kerr, D Kerr, MN Passarelli, JC Figueiredo, DD Buchanan, AK Win, JL Hopper, MA Jenkins, NM Lindor, PA Newcomb, S Gallinger, D Conti, F Schumacher, G Casey, LA Aaltonen, JP Cheadle, IP Tomlinson, MG Dunlop, RS Houlston
Publication Date: 2017-06-15

Variant appearance in text: rs17145738
PubMed Link: 28340513
Variant Present in the following documents:
  • NIHMS79344-supplement-Supplementary_Data.pdf
  • NIHMS79344-supplement-Supplementary_Material.pdf
View BVdb publication page



Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits.

American Journal Of Human Genetics
M Civelek, Y Wu, C Pan, CK Raulerson, A Ko, A He, C Tilford, NK Saleem, A Stančáková, LJ Scott, C Fuchsberger, HM Stringham, AU Jackson, N Narisu, PS Chines, KS Small, J Kuusisto, BW Parks, P Pajukanta, T Kirchgessner, FS Collins, PS Gargalovic, M Boehnke, M Laakso, KL Mohlke, AJ Lusis
Publication Date: 2017-03-02

Variant appearance in text: rs17145738
PubMed Link: 28257690
Variant Present in the following documents:
  • mmc3.xlsx
View BVdb publication page



Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study.

Scientific Reports
S Christie, S Robiou-du-Pont, SS Anand, KM Morrison, SD McDonald, G Paré, SA Atkinson, KK Teo, D Meyre
Publication Date: 2017-03-06

Variant appearance in text: rs17145738
PubMed Link: 28250428
Variant Present in the following documents:
  • 41598_2017_102_MOESM1_ESM.pdf
  • aaaaaMain text
View BVdb publication page



Paraoxonase-1 (PON1) rs662 Polymorphism and Its Association with Serum Lipid Levels and Longevity in the Bama Zhuang Population.

Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research
Y Li, G Liang, L Shi, X Liang, B Long, J Qin, Z Zhang
Publication Date: 2016-12-27

Variant appearance in text: rs17145738
PubMed Link: 28027289
Variant Present in the following documents:
  • Main text
View BVdb publication page



Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters.

Cell
BM Javierre, OS Burren, SP Wilder, R Kreuzhuber, SM Hill, S Sewitz, J Cairns, SW Wingett, C Várnai, MJ Thiecke, F Burden, S Farrow, AJ Cutler, K Rehnström, K Downes, L Grassi, M Kostadima, P Freire-Pritchett, F Wang, , HG Stunnenberg, JA Todd, DR Zerbino, O Stegle, WH Ouwehand, M Frontini, C Wallace, M Spivakov, P Fraser
Publication Date: 2016-11-17

Variant appearance in text: rs17145738
PubMed Link: 27863249
Variant Present in the following documents:
  • mmc3.xlsx
View BVdb publication page



Comprehensive Analysis of Established Dyslipidemia-Associated Loci in the Diabetes Prevention Program.

Circulation. Cardiovascular Genetics
TV Varga, AH Winters, KA Jablonski, ES Horton, P Khare-Ranade, WC Knowler, SM Marcovina, F Renström, KE Watson, R Goldberg, JC Florez, TI Pollin, PW Franks
Publication Date: 2016-12

Variant appearance in text: rs17145738
PubMed Link: 27784733
Variant Present in the following documents:
  • NIHMS825913-supplement-001457_-_Supplemental_Material.pdf
View BVdb publication page



Is High-Density Lipoprotein Cholesterol Causally Related to Kidney Function? Evidence From Genetic Epidemiological Studies.

Arteriosclerosis, Thrombosis, And Vascular Biology
S Coassin, S Friedel, A Köttgen, C Lamina, F Kronenberg
Publication Date: 2016-11

Variant appearance in text: rs17145738
PubMed Link: 27687604
Variant Present in the following documents:
  • atv-36-2252-s002.pdf
View BVdb publication page



Advances in Integrating Traditional and Omic Biomarkers When Analyzing the Effects of the Mediterranean Diet Intervention in Cardiovascular Prevention.

International Journal Of Molecular Sciences
M Fitó, O Melander, JA Martínez, E Toledo, C Carpéné, D Corella
Publication Date: 2016-09-02

Variant appearance in text: rs17145738
PubMed Link: 27598147
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic susceptibility to dyslipidemia and incidence of cardiovascular disease depending on a diet quality index in the Malmö Diet and Cancer cohort.

Genes & Nutrition
S Hellstrand, U Ericson, CA Schulz, I Drake, B Gullberg, B Hedblad, G Engström, M Orho-Melander, E Sonestedt
Publication Date: 2016

Variant appearance in text: rs17145738
PubMed Link: 27551321
Variant Present in the following documents:
  • 12263_2016_536_MOESM1_ESM.docx
View BVdb publication page



Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases.

Science (New York, N.Y.)
O Franzén, R Ermel, A Cohain, NK Akers, A Di Narzo, HA Talukdar, H Foroughi-Asl, C Giambartolomei, JF Fullard, K Sukhavasi, S Köks, LM Gan, C Giannarelli, JC Kovacic, C Betsholtz, B Losic, T Michoel, K Hao, P Roussos, J Skogsberg, A Ruusalepp, EE Schadt, JL Björkegren
Publication Date: 2016-08-19

Variant appearance in text: rs17145738
PubMed Link: 27540175
Variant Present in the following documents:
  • NIHMS865440-supplement-Figure_S41.pdf
View BVdb publication page



Analysis with the exome array identifies multiple new independent variants in lipid loci.

Human Molecular Genetics
S Kanoni, NG Masca, KE Stirrups, TV Varga, HR Warren, RA Scott, L Southam, W Zhang, H Yaghootkar, M Müller-Nurasyid, A Couto Alves, RJ Strawbridge, L Lataniotis, N An Hashim, C Besse, A Boland, PS Braund, JM Connell, A Dominiczak, AE Farmaki, S Franks, H Grallert, JH Jansson, M Karaleftheri, S Keinänen-Kiukaanniemi, A Matchan, D Pasko, A Peters, N Poulter, NW Rayner, F Renström, O Rolandsson, M Sabater-Lleal, B Sennblad, P Sever, D Shields, A Silveira, AV Stanton, K Strauch, M Tomaszewski, E Tsafantakis, M Waldenberger, AI Blakemore, G Dedoussis, SA Escher, JS Kooner, MI McCarthy, CN Palmer, , A Hamsten, MJ Caulfield, TM Frayling, MD Tobin, MR Jarvelin, E Zeggini, C Gieger, JC Chambers, NJ Wareham, PB Munroe, PW Franks, NJ Samani, P Deloukas
Publication Date: 2016-09-15

Variant appearance in text: rs17145738
PubMed Link: 27466198
Variant Present in the following documents:
  • Main text
View BVdb publication page



Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.

Plos Medicine
BP Prins, A Abbasi, A Wong, A Vaez, I Nolte, N Franceschini, PE Stuart, J Guterriez Achury, V Mistry, JP Bradfield, AM Valdes, J Bras, A Shatunov, , , , , , , , , , , , , , , C Lu, B Han, S Raychaudhuri, S Bevan, MD Mayes, LC Tsoi, E Evangelou, RP Nair, SF Grant, C Polychronakos, TR Radstake, DA van Heel, ML Dunstan, NW Wood, A Al-Chalabi, A Dehghan, H Hakonarson, HS Markus, JT Elder, J Knight, DE Arking, TD Spector, BP Koeleman, CM van Duijn, J Martin, AP Morris, RK Weersma, C Wijmenga, PB Munroe, JR Perry, JG Pouget, Y Jamshidi, H Snieder, BZ Alizadeh
Publication Date: 2016-06

Variant appearance in text: rs17145738
PubMed Link: 27327646
Variant Present in the following documents:
  • pmed.1001976.s002.xlsx
  • pmed.1001976.s012.xlsx
View BVdb publication page



Detection and interpretation of shared genetic influences on 42 human traits.

Nature Genetics
JK Pickrell, T Berisa, JZ Liu, L Ségurel, JY Tung, DA Hinds
Publication Date: 2016-07

Variant appearance in text: rs17145738
PubMed Link: 27182965
Variant Present in the following documents:
  • NIHMS780506-supplement-12.pdf
View BVdb publication page



Targeted exonic sequencing of GWAS loci in the high extremes of the plasma lipids distribution.

Atherosclerosis
AP Patel, GM Peloso, JP Pirruccello, CT Johansen, JB Dubé, DB Larach, MR Ban, GM Dallinge-Thie, N Gupta, M Boehnke, GR Abecasis, JJ Kastelein, GK Hovingh, RA Hegele, DJ Rader, S Kathiresan
Publication Date: 2016-07

Variant appearance in text: rs17145738
PubMed Link: 27182959
Variant Present in the following documents:
  • NIHMS787201-supplement.pdf
View BVdb publication page



Diet Quality and Change in Blood Lipids during 16 Years of Follow-up and Their Interaction with Genetic Risk for Dyslipidemia.

Nutrients
E Sonestedt, S Hellstrand, I Drake, CA Schulz, U Ericson, J Hlebowicz, MM Persson, B Gullberg, B Hedblad, G Engström, M Orho-Melander
Publication Date: 2016-05-09

Variant appearance in text: rs17145738
PubMed Link: 27171109
Variant Present in the following documents:
  • nutrients-08-00274-s001.doc
View BVdb publication page



Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants.

Aging
LC Pilling, JL Atkins, K Bowman, SE Jones, J Tyrrell, RN Beaumont, KS Ruth, MA Tuke, H Yaghootkar, AR Wood, RM Freathy, A Murray, MN Weedon, L Xue, K Lunetta, JM Murabito, LW Harries, JM Robine, C Brayne, GA Kuchel, L Ferrucci, TM Frayling, D Melzer
Publication Date: 2016-03

Variant appearance in text: rs17145738
PubMed Link: 27015805
Variant Present in the following documents:
  • aging-08-547-s003.docx
View BVdb publication page



Interaction of Insulin Resistance and Related Genetic Variants With Triglyceride-Associated Genetic Variants.

Circulation. Cardiovascular Genetics
YC Klimentidis, A Arora
Publication Date: 2016-04

Variant appearance in text: rs17145738
PubMed Link: 26850992
Variant Present in the following documents:
  • NIHMS758238-supplement-001246_-_Supplemental_Material.pdf
View BVdb publication page



Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.

Scientific Reports
JE Below, EJ Parra, ER Gamazon, J Torres, S Krithika, S Candille, Y Lu, A Manichakul, J Peralta-Romero, Q Duan, Y Li, AP Morris, O Gottesman, E Bottinger, XQ Wang, KD Taylor, YD Ida Chen, JI Rotter, SS Rich, RJ Loos, H Tang, NJ Cox, M Cruz, CL Hanis, A Valladares-Salgado
Publication Date: 2016-01-19

Variant appearance in text: rs17145738
PubMed Link: 26780889
Variant Present in the following documents:
  • srep19429-s2.xls
View BVdb publication page



INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES.

Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing
A Verma, JB Leader, SS Verma, A Frase, J Wallace, S Dudek, DR Lavage, CV Van Hout, FE Dewey, J Penn, A Lopez, JD Overton, DJ Carey, DH Ledbetter, HL Kirchner, MD Ritchie, SA Pendergrass
Publication Date: 2016

Variant appearance in text: rs17145738
PubMed Link: 26776183
Variant Present in the following documents:
  • NIHMS742521-supplement-2.pdf
View BVdb publication page



Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese.

Nature Communications
CS Tang, H Zhang, CY Cheung, M Xu, JC Ho, W Zhou, SS Cherny, Y Zhang, O Holmen, KW Au, H Yu, L Xu, J Jia, RM Porsch, L Sun, W Xu, H Zheng, LY Wong, Y Mu, J Dou, CH Fong, S Wang, X Hong, L Dong, Y Liao, J Wang, LS Lam, X Su, H Yan, ML Yang, J Chen, CW Siu, G Xie, YC Woo, Y Wu, KC Tan, K Hveem, BM Cheung, S Zöllner, A Xu, Y Eugene Chen, CQ Jiang, Y Zhang, TH Lam, SK Ganesh, Y Huo, PC Sham, KS Lam, CJ Willer, HF Tse, W Gao
Publication Date: 2015-12-22

Variant appearance in text: rs17145738
PubMed Link: 26690388
Variant Present in the following documents:
  • ncomms10206-s1.pdf
  • ncomms10206-s2.xlsx
View BVdb publication page



Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians.

Diabetologia
AK Nair, P Piaggi, NA McLean, M Kaur, S Kobes, WC Knowler, C Bogardus, RL Hanson, LJ Baier
Publication Date: 2016-03

Variant appearance in text: rs17145738
PubMed Link: 26670163
Variant Present in the following documents:
  • NIHMS745539-supplement-125_2015_3835_MOESM1_ESM.pdf
View BVdb publication page



Genomic and transcriptomic predictors of triglyceride response to regular exercise.

British Journal Of Sports Medicine
MA Sarzynski, PK Davidsen, YJ Sung, MK Hesselink, P Schrauwen, TK Rice, DC Rao, F Falciani, C Bouchard
Publication Date: 2015-12

Variant appearance in text: rs17145738
PubMed Link: 26491034
Variant Present in the following documents:
  • NIHMS735601-supplement-Supplementary_Material.pdf
View BVdb publication page



Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome.

Nature Communications
FR Day, DA Hinds, JY Tung, L Stolk, U Styrkarsdottir, R Saxena, A Bjonnes, L Broer, DB Dunger, BV Halldorsson, DA Lawlor, G Laval, I Mathieson, WL McCardle, Y Louwers, C Meun, S Ring, RA Scott, P Sulem, AG Uitterlinden, NJ Wareham, U Thorsteinsdottir, C Welt, K Stefansson, JSE Laven, KK Ong, JRB Perry
Publication Date: 2015-09-29

Variant appearance in text: rs17145738
PubMed Link: 26416764
Variant Present in the following documents:
  • ncomms9464-s2.xlsx
View BVdb publication page



The Use of Non-Variant Sites to Improve the Clinical Assessment of Whole-Genome Sequence Data.

Plos One
A Ferrarini, L Xumerle, F Griggio, M Garonzi, C Cantaloni, C Centomo, SM Vargas, P Descombes, J Marquis, S Collino, C Franceschi, P Garagnani, BA Salisbury, JM Harvey, M Delledonne
Publication Date: 2015

Variant appearance in text: rs17145738
PubMed Link: 26147798
Variant Present in the following documents:
  • pone.0132180.s006.xlsx
View BVdb publication page



Evaluation of transethnic fine mapping with population-specific and cosmopolitan imputation reference panels in diverse Asian populations.

European Journal Of Human Genetics : Ejhg
X Wang, CY Cheng, J Liao, X Sim, J Liu, KS Chia, ES Tai, P Little, CC Khor, T Aung, TY Wong, YY Teo
Publication Date: 2016-04

Variant appearance in text: rs17145738
PubMed Link: 26130488
Variant Present in the following documents:
  • ejhg2015150x4.xls
View BVdb publication page



Apolipoprotein E and protection against hepatitis E viral infection in American non-Hispanic blacks.

Hepatology (Baltimore, Md.)
L Zhang, A Yesupriya, MH Chang, E Teshale, CG Teo
Publication Date: 2015-11

Variant appearance in text: rs17145738
PubMed Link: 26096528
Variant Present in the following documents:
  • NIHMS1043972-supplement-Supplemental.pdf
View BVdb publication page



Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.

Plos Medicine
SD Østergaard, S Mukherjee, SJ Sharp, P Proitsi, LA Lotta, F Day, JR Perry, KL Boehme, S Walter, JS Kauwe, LE Gibbons, , , , EB Larson, JF Powell, C Langenberg, PK Crane, NJ Wareham, RA Scott
Publication Date: 2015-06

Variant appearance in text: rs17145738
PubMed Link: 26079503
Variant Present in the following documents:
  • pmed.1001841.s014.xlsx
View BVdb publication page



Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease.

Human Genetics
X Zhang, W Zhang, SL Saraf, M Nouraie, J Han, M Gowhari, J Hassan, G Miasnikova, A Sergueeva, S Nekhai, R Kittles, RF Machado, JG Garcia, MT Gladwin, MH Steinberg, P Sebastiani, DA McClain, VR Gordeuk
Publication Date: 2015-08

Variant appearance in text: rs17145738
PubMed Link: 26025476
Variant Present in the following documents:
  • NIHMS729106-supplement-Supplemental_Tables.xls
View BVdb publication page



The impact of low-frequency and rare variants on lipid levels.

Nature Genetics
I Surakka, M Horikoshi, R Mägi, AP Sarin, A Mahajan, V Lagou, L Marullo, T Ferreira, B Miraglio, S Timonen, J Kettunen, M Pirinen, J Karjalainen, G Thorleifsson, S Hägg, JJ Hottenga, A Isaacs, C Ladenvall, M Beekman, T Esko, JS Ried, CP Nelson, C Willenborg, S Gustafsson, HJ Westra, M Blades, AJ de Craen, EJ de Geus, J Deelen, H Grallert, A Hamsten, AS Havulinna, C Hengstenberg, JJ Houwing-Duistermaat, E Hyppönen, LC Karssen, T Lehtimäki, V Lyssenko, PK Magnusson, E Mihailov, M Müller-Nurasyid, JP Mpindi, NL Pedersen, BW Penninx, M Perola, TH Pers, A Peters, J Rung, JH Smit, V Steinthorsdottir, MD Tobin, N Tsernikova, EM van Leeuwen, JS Viikari, SM Willems, G Willemsen, H Schunkert, J Erdmann, NJ Samani, J Kaprio, L Lind, C Gieger, A Metspalu, PE Slagboom, L Groop, CM van Duijn, JG Eriksson, A Jula, V Salomaa, DI Boomsma, C Power, OT Raitakari, E Ingelsson, MR Järvelin, U Thorsteinsdottir, L Franke, E Ikonen, O Kallioniemi, V Pietiäinen, CM Lindgren, K Stefansson, A Palotie, MI McCarthy, AP Morris, I Prokopenko, S Ripatti,
Publication Date: 2015-06

Variant appearance in text: rs17145738
PubMed Link: 25961943
Variant Present in the following documents:
  • NIHMS67068-supplement-Supplementary_tables_1-7__9-14.docx
View BVdb publication page



Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array.

European Journal Of Human Genetics : Ejhg
S Rodriguez, TR Gaunt, Y Guo, J Zheng, MR Barnes, W Tang, F Danish, A Johnson, BA Castillo, YR Li, H Hakonarson, SG Buxbaum, T Palmer, MY Tsai, LA Lange, S Ebrahim, G Davey Smith, DA Lawlor, AR Folsom, R Hoogeveen, A Reiner, B Keating, IN Day
Publication Date: 2016-01

Variant appearance in text: rs17145738
PubMed Link: 25920552
Variant Present in the following documents:
  • ejhg201563x1.doc
View BVdb publication page



The association between carbohydrate-rich foods and risk of cardiovascular disease is not modified by genetic susceptibility to dyslipidemia as determined by 80 validated variants.

Plos One
E Sonestedt, S Hellstrand, CA Schulz, P Wallström, I Drake, U Ericson, B Gullberg, B Hedblad, M Orho-Melander
Publication Date: 2015

Variant appearance in text: rs17145738
PubMed Link: 25898210
Variant Present in the following documents:
  • pone.0126104.s004.doc
View BVdb publication page



Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein.

Plos One
S Ligthart, PS de Vries, AG Uitterlinden, A Hofman, , OH Franco, DI Chasman, A Dehghan
Publication Date: 2015

Variant appearance in text: rs17145738
PubMed Link: 25768928
Variant Present in the following documents:
  • Main text
  • pone.0118859.s003.docx
  • pone.0118859.s004.docx
View BVdb publication page



Association between CETP, MLXIPL, and TOMM40 polymorphisms and serum lipid levels in a Latvian population.

Meta Gene
I Radovica, D Fridmanis, I Silamikelis, L Nikitina-Zake, J Klovins
Publication Date: 2014-12

Variant appearance in text: rs17145738
PubMed Link: 25606439
Variant Present in the following documents:
  • Main text
  • mmc1.docx
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Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study.

Plos Genetics
MA Hall, A Verma, KD Brown-Gentry, R Goodloe, J Boston, S Wilson, B McClellan, C Sutcliffe, HH Dilks, NB Gillani, H Jin, P Mayo, M Allen, N Schnetz-Boutaud, DC Crawford, MD Ritchie, SA Pendergrass
Publication Date: 2014-12

Variant appearance in text: rs17145738
PubMed Link: 25474351
Variant Present in the following documents:
  • pgen.1004678.s007.xlsx
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Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.

Nature Communications
B Benyamin, T Esko, JS Ried, A Radhakrishnan, SH Vermeulen, M Traglia, M Gögele, D Anderson, L Broer, C Podmore, J Luan, Z Kutalik, S Sanna, P van der Meer, T Tanaka, F Wang, HJ Westra, L Franke, E Mihailov, L Milani, J Hälldin, J Häldin, J Winkelmann, T Meitinger, J Thiery, A Peters, M Waldenberger, A Rendon, J Jolley, J Sambrook, LA Kiemeney, FC Sweep, CF Sala, C Schwienbacher, I Pichler, J Hui, A Demirkan, A Isaacs, N Amin, M Steri, G Waeber, N Verweij, JE Powell, DR Nyholt, AC Heath, PA Madden, PM Visscher, MJ Wright, GW Montgomery, NG Martin, D Hernandez, S Bandinelli, P van der Harst, M Uda, P Vollenweider, RA Scott, C Langenberg, NJ Wareham, , C van Duijn, J Beilby, PP Pramstaller, AA Hicks, WH Ouwehand, K Oexle, C Gieger, A Metspalu, C Camaschella, D Toniolo, DW Swinkels, JB Whitfield
Publication Date: 2014-10-29

Variant appearance in text: rs17145738
PubMed Link: 25352340
Variant Present in the following documents:
  • NIHMS619770-supplement-1.pdf
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Using multivariable Mendelian randomization to disentangle the causal effects of lipid fractions.

Plos One
S Burgess, DF Freitag, H Khan, DN Gorman, SG Thompson
Publication Date: 2014

Variant appearance in text: rs17145738
PubMed Link: 25302496
Variant Present in the following documents:
  • Main text
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Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis.

Plos Medicine
P Proitsi, MK Lupton, L Velayudhan, S Newhouse, I Fogh, M Tsolaki, M Daniilidou, M Pritchard, I Kloszewska, H Soininen, P Mecocci, B Vellas, , J Williams, , R Stewart, P Sham, S Lovestone, JF Powell
Publication Date: 2014-09

Variant appearance in text: rs17145738
PubMed Link: 25226301
Variant Present in the following documents:
  • pmed.1001713.s003.xlsx
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Multiple associated variants increase the heritability explained for plasma lipids and coronary artery disease.

Circulation. Cardiovascular Genetics
H Tada, HH Won, O Melander, J Yang, GM Peloso, S Kathiresan
Publication Date: 2014-10

Variant appearance in text: rs17145738
PubMed Link: 25170055
Variant Present in the following documents:
  • NIHMS664832-supplement-supplement.doc
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Strategies to fine-map genetic associations with lipid levels by combining epigenomic annotations and liver-specific transcription profiles.

Genomics
KS Lo, S Vadlamudi, MP Fogarty, KL Mohlke, G Lettre
Publication Date: 2014-08

Variant appearance in text: rs17145738
PubMed Link: 24997396
Variant Present in the following documents:
  • Main text
View BVdb publication page



Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
NM_001362660.2 c.*1963G>A - 3_prime_UTR_variant 8/8 -
NM_001362661.2 c.*1963G>A - 3_prime_UTR_variant 7/7 -
NM_001362662.2 c.*1963G>A - 3_prime_UTR_variant 8/8 -
NM_001362663.2 c.*1963G>A - 3_prime_UTR_variant 8/8 -
NM_012453.4 c.*1963G>A - 3_prime_UTR_variant 7/7 -