A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids.
Nature Communications
Jhun, Min-A MA; Mendelson, Michael M; Wilson, Rory R; Gondalia, Rahul R; Joehanes, Roby R; Salfati, Elias E; Zhao, Xiaoping X; Braun, Kim Valeska Emilie KVE; Do, Anh Nguyet AN; Hedman, Åsa K ÅK; Zhang, Tao T; Carnero-Montoro, Elena E; Shen, Jincheng J; Bartz, Traci M TM; Brody, Jennifer A JA; Montasser, May E ME; O'Connell, Jeff R JR; Yao, Chen C; Xia, Rui R; Boerwinkle, Eric E; Grove, Megan M; Guan, Weihua W; Liliane, Pfeiffer P; Singmann, Paula P; Müller-Nurasyid, Martina M; Meitinger, Thomas T; Gieger, Christian C; Peters, Annette A; Zhao, Wei W; Ware, Erin B EB; Smith, Jennifer A JA; Dhana, Klodian K; van Meurs, Joyce J; Uitterlinden, Andre A; Ikram, Mohammad Arfan MA; Ghanbari, Mohsen M; Zhi, Deugi D; Gustafsson, Stefan S; Lind, Lars L; Li, Shengxu S; Sun, Dianjianyi D; Spector, Tim D TD; Chen, Yii-der Ida YI; Damcott, Coleen C; Shuldiner, Alan R AR; Absher, Devin M DM; Horvath, Steve S; Tsao, Philip S PS; Kardia, Sharon S; Psaty, Bruce M BM; Sotoodehnia, Nona N; Bell, Jordana T JT; Ingelsson, Erik E; Chen, Wei W; Dehghan, Abbas A; Arnett, Donna K DK; Waldenberger, Melanie M; Hou, Lifang L; Whitsel, Eric A EA; Baccarelli, Andrea A; Levy, Daniel D; Fornage, Myriam M; Irvin, Marguerite R MR; Assimes, Themistocles L TL
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.
Nature Communications
Nielsen, Jonas B JB; Rom, Oren O; Surakka, Ida I; Graham, Sarah E SE; Zhou, Wei W; Roychowdhury, Tanmoy T; Fritsche, Lars G LG; Gagliano Taliun, Sarah A SA; Sidore, Carlo C; Liu, Yuhao Y; Gabrielsen, Maiken E ME; Skogholt, Anne Heidi AH; Wolford, Brooke B; Overton, William W; Zhao, Ying Y; Chen, Jin J; Zhang, He H; Hornsby, Whitney E WE; Acheampong, Akua A; Grooms, Austen A; Schaefer, Amanda A; Zajac, Gregory J M GJM; Villacorta, Luis L; Zhang, Jifeng J; Brumpton, Ben B; Løset, Mari M; Rai, Vivek V; Lundegaard, Pia R PR; Olesen, Morten S MS; Taylor, Kent D KD; Palmer, Nicholette D ND; Chen, Yii-Der YD; Choi, Seung H SH; Lubitz, Steven A SA; Ellinor, Patrick T PT; Barnes, Kathleen C KC; Daya, Michelle M; Rafaels, Nicholas N; Weiss, Scott T ST; Lasky-Su, Jessica J; Tracy, Russell P RP; Vasan, Ramachandran S RS; Cupples, L Adrienne LA; Mathias, Rasika A RA; Yanek, Lisa R LR; Becker, Lewis C LC; Peyser, Patricia A PA; Bielak, Lawrence F LF; Smith, Jennifer A JA; Aslibekyan, Stella S; Hidalgo, Bertha A BA; Arnett, Donna K DK; Irvin, Marguerite R MR; Wilson, James G JG; Musani, Solomon K SK; Correa, Adolfo A; Rich, Stephen S SS; Guo, Xiuqing X; Rotter, Jerome I JI; Konkle, Barbara A BA; Johnsen, Jill M JM; Ashley-Koch, Allison E AE; Telen, Marilyn J MJ; Sheehan, Vivien A VA; Blangero, John J; Curran, Joanne E JE; Peralta, Juan M JM; Montgomery, Courtney C; Sheu, Wayne H-H WH; Chung, Ren-Hua RH; Schwander, Karen K; Nouraie, Seyed M SM; Gordeuk, Victor R VR; Zhang, Yingze Y; Kooperberg, Charles C; Reiner, Alexander P AP; Jackson, Rebecca D RD; Bleecker, Eugene R ER; Meyers, Deborah A DA; Li, Xingnan X; Das, Sayantan S; Yu, Ketian K; LeFaive, Jonathon J; Smith, Albert A; Blackwell, Tom T; Taliun, Daniel D; Zollner, Sebastian S; Forer, Lukas L; Schoenherr, Sebastian S; Fuchsberger, Christian C; Pandit, Anita A; Zawistowski, Matthew M; Kheterpal, Sachin S; Brummett, Chad M CM; Natarajan, Pradeep P; Schlessinger, David D; Lee, Seunggeun S; Kang, Hyun Min HM; Cucca, Francesco F; Holmen, Oddgeir L OL; Åsvold, Bjørn O BO; Boehnke, Michael M; Kathiresan, Sekar S; Abecasis, Goncalo R GR; Chen, Y Eugene YE; Willer, Cristen J CJ; Hveem, Kristian K
Circulating Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor Binding Protein 3 Associate With Risk of Colorectal Cancer Based on Serologic and Mendelian Randomization Analyses.
Gastroenterology
Murphy, Neil N; Carreras-Torres, Robert R; Song, Mingyang M; Chan, Andrew T AT; Martin, Richard M RM; Papadimitriou, Nikos N; Dimou, Niki N; Tsilidis, Konstantinos K KK; Banbury, Barbara B; Bradbury, Kathryn E KE; Besevic, Jelena J; Rinaldi, Sabina S; Riboli, Elio E; Cross, Amanda J AJ; Travis, Ruth C RC; Agnoli, Claudia C; Albanes, Demetrius D; Berndt, Sonja I SI; Bézieau, Stéphane S; Bishop, D Timothy DT; Brenner, Hermann H; Buchanan, Daniel D DD; Onland-Moret, N Charlotte NC; Burnett-Hartman, Andrea A; Campbell, Peter T PT; Casey, Graham G; Castellví-Bel, Sergi S; Chang-Claude, Jenny J; Chirlaque, María-Dolores MD; de la Chapelle, Albert A; English, Dallas D; Figueiredo, Jane C JC; Gallinger, Steven J SJ; Giles, Graham G GG; Gruber, Stephen B SB; Gsur, Andrea A; Hampe, Jochen J; Hampel, Heather H; Harrison, Tabitha A TA; Hoffmeister, Michael M; Hsu, Li L; Huang, Wen-Yi WY; Huyghe, Jeroen R JR; Jenkins, Mark A MA; Keku, Temitope O TO; Kühn, Tilman T; Kweon, Sun-Seog SS; Le Marchand, Loic L; Li, Christopher I CI; Li, Li L; Lindblom, Annika A; Martín, Vicente V; Milne, Roger L RL; Moreno, Victor V; Newcomb, Polly A PA; Offit, Kenneth K; Ogino, Shuji S; Ose, Jennifer J; Perduca, Vittorio V; Phipps, Amanda I AI; Platz, Elizabeth A EA; Potter, John D JD; Qu, Conghui C; Rennert, Gad G; Sakoda, Lori C LC; Schafmayer, Clemens C; Schoen, Robert E RE; Slattery, Martha L ML; Tangen, Catherine M CM; Ulrich, Cornelia M CM; van Duijnhoven, Franzel J B FJB; Van Guelpen, Bethany B; Visvanathan, Kala K; Vodicka, Pavel P; Vodickova, Ludmila L; Vymetalkova, Veronika V; Wang, Hansong H; White, Emily E; Wolk, Alicja A; Woods, Michael O MO; Wu, Anna H AH; Zheng, Wei W; Peters, Ulrike U; Gunter, Marc J MJ
Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans.
Nature Metabolism
Garske, Kristina M KM; Pan, David Z DZ; Miao, Zong Z; Bhagat, Yash V YV; Comenho, Caroline C; Robles, Christopher R CR; Benhammou, Jihane N JN; Alvarez, Marcus M; Ko, Arthur A; Ye, Chun Jimmie CJ; Pisegna, Joseph R JR; Mohlke, Karen L KL; Sinsheimer, Janet S JS; Laakso, Markku M; Pajukanta, Päivi P
Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study.
Diabetes
Sobrin, Lucia L; Chong, Yong He YH; Fan, Qiao Q; Gan, Alfred A; Stanwyck, Lynn K LK; Kaidonis, Georgia G; Craig, Jamie E JE; Kim, Jihye J; Liao, Wen-Ling WL; Huang, Yu-Chuen YC; Lee, Wen-Jane WJ; Hung, Yi-Jen YJ; Guo, Xiuqing X; Hai, Yang Y; Ipp, Eli E; Pollack, Samuela S; Hancock, Heather H; Price, Alkes A; Penman, Alan A; Mitchell, Paul P; Liew, Gerald G; Smith, Albert V AV; Gudnason, Vilmundur V; Tan, Gavin G; Klein, Barbara E K BEK; Kuo, Jane J; Li, Xiaohui X; Christiansen, Mark W MW; Psaty, Bruce M BM; Sandow, Kevin K; , ; Jensen, Richard A RA; Klein, Ronald R; Cotch, Mary Frances MF; Wang, Jie Jin JJ; Jia, Yucheng Y; Chen, Ching J CJ; Chen, Yii-Der Ida YI; Rotter, Jerome I JI; Tsai, Fuu-Jen FJ; Hanis, Craig L CL; Burdon, Kathryn P KP; Wong, Tien Yin TY; Cheng, Ching-Yu CY
HDL-cholesterol concentration in pregnant Chinese Han women of late second trimester associated with genetic variants in CETP, ABCA1, APOC3, and GALNT2.
Oncotarget
Cui, Mingxuan M; Li, Wei W; Ma, Liangkun L; Ping, Fan F; Liu, Juntao J; Wu, Xueyan X; Mao, Jiangfeng J; Wang, Xi X; Nie, Min M
Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci.
Human Molecular Genetics
Zubair, Niha N; Graff, Mariaelisa M; Luis Ambite, Jose J; Bush, William S WS; Kichaev, Gleb G; Lu, Yingchang Y; Manichaikul, Ani A; Sheu, Wayne H-H WH; Absher, Devin D; Assimes, Themistocles L TL; Bielinski, Suzette J SJ; Bottinger, Erwin P EP; Buzkova, Petra P; Chuang, Lee-Ming LM; Chung, Ren-Hua RH; Cochran, Barbara B; Dumitrescu, Logan L; Gottesman, Omri O; Haessler, Jeffrey W JW; Haiman, Christopher C; Heiss, Gerardo G; Hsiung, Chao A CA; Hung, Yi-Jen YJ; Hwu, Chii-Min CM; Juang, Jyh-Ming J JJ; Le Marchand, Loic L; Lee, I-Te IT; Lee, Wen-Jane WJ; Lin, Li-An LA; Lin, Danyu D; Lin, Shih-Yi SY; Mackey, Rachel H RH; Martin, Lisa W LW; Pasaniuc, Bogdan B; Peters, Ulrike U; Predazzi, Irene I; Quertermous, Thomas T; Reiner, Alex P AP; Robinson, Jennifer J; Rotter, Jerome I JI; Ryckman, Kelli K KK; Schreiner, Pamela J PJ; Stahl, Eli E; Tao, Ran R; Tsai, Michael Y MY; Waite, Lindsay L LL; Wang, Tzung-Dau TD; Buyske, Steven S; Ida Chen, Yii-Der YD; Cheng, Iona I; Crawford, Dana C DC; Loos, Ruth J F RJF; Rich, Stephen S SS; Fornage, Myriam M; North, Kari E KE; Kooperberg, Charles C; Carty, Cara L CL
Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study.
Scientific Reports
Christie, Shanice S; Robiou-du-Pont, Sébastien S; Anand, Sonia S SS; Morrison, Katherine M KM; McDonald, Sarah D SD; Paré, Guillaume G; Atkinson, Stephanie A SA; Teo, Koon K KK; Meyre, David D
Advances in Integrating Traditional and Omic Biomarkers When Analyzing the Effects of the Mediterranean Diet Intervention in Cardiovascular Prevention.
International Journal Of Molecular Sciences
Fitó, Montserrat M; Melander, Olle O; Martínez, José Alfredo JA; Toledo, Estefanía E; Carpéné, Christian C; Corella, Dolores D
Analysis with the exome array identifies multiple new independent variants in lipid loci.
Human Molecular Genetics
Kanoni, Stavroula S; Masca, Nicholas G D NG; Stirrups, Kathleen E KE; Varga, Tibor V TV; Warren, Helen R HR; Scott, Robert A RA; Southam, Lorraine L; Zhang, Weihua W; Yaghootkar, Hanieh H; Müller-Nurasyid, Martina M; Couto Alves, Alexessander A; Strawbridge, Rona J RJ; Lataniotis, Lazaros L; An Hashim, Nikman N; Besse, Céline C; Boland, Anne A; Braund, Peter S PS; Connell, John M JM; Dominiczak, Anna A; Farmaki, Aliki-Eleni AE; Franks, Stephen S; Grallert, Harald H; Jansson, Jan-Håkan JH; Karaleftheri, Maria M; Keinänen-Kiukaanniemi, Sirkka S; Matchan, Angela A; Pasko, Dorota D; Peters, Annette A; Poulter, Neil N; Rayner, Nigel W NW; Renström, Frida F; Rolandsson, Olov O; Sabater-Lleal, Maria M; Sennblad, Bengt B; Sever, Peter P; Shields, Denis D; Silveira, Angela A; Stanton, Alice V AV; Strauch, Konstantin K; Tomaszewski, Maciej M; Tsafantakis, Emmanouil E; Waldenberger, Melanie M; Blakemore, Alexandra I F AI; Dedoussis, George G; Escher, Stefan A SA; Kooner, Jaspal S JS; McCarthy, Mark I MI; Palmer, Colin N A CN; , ; Hamsten, Anders A; Caulfield, Mark J MJ; Frayling, Timothy M TM; Tobin, Martin D MD; Jarvelin, Marjo-Riitta MR; Zeggini, Eleftheria E; Gieger, Christian C; Chambers, John C JC; Wareham, Nick J NJ; Munroe, Patricia B PB; Franks, Paul W PW; Samani, Nilesh J NJ; Deloukas, Panos P
Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese.
Nature Communications
Tang, Clara S CS; Zhang, He H; Cheung, Chloe Y Y CY; Xu, Ming M; Ho, Jenny C Y JC; Zhou, Wei W; Cherny, Stacey S SS; Zhang, Yan Y; Holmen, Oddgeir O; Au, Ka-Wing KW; Yu, Haiyi H; Xu, Lin L; Jia, Jia J; Porsch, Robert M RM; Sun, Lijie L; Xu, Weixian W; Zheng, Huiping H; Wong, Lai-Yung LY; Mu, Yiming Y; Dou, Jingtao J; Fong, Carol H Y CH; Wang, Shuyu S; Hong, Xueyu X; Dong, Liguang L; Liao, Yanhua Y; Wang, Jiansong J; Lam, Levina S M LS; Su, Xi X; Yan, Hua H; Yang, Min-Lee ML; Chen, Jin J; Siu, Chung-Wah CW; Xie, Gaoqiang G; Woo, Yu-Cho YC; Wu, Yangfeng Y; Tan, Kathryn C B KC; Hveem, Kristian K; Cheung, Bernard M Y BM; Zöllner, Sebastian S; Xu, Aimin A; Eugene Chen, Y Y; Jiang, Chao Qiang CQ; Zhang, Youyi Y; Lam, Tai-Hing TH; Ganesh, Santhi K SK; Huo, Yong Y; Sham, Pak C PC; Lam, Karen S L KS; Willer, Cristen J CJ; Tse, Hung-Fat HF; Gao, Wei W
Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.
Nature Communications
Benyamin, Beben B; Esko, Tonu T; Ried, Janina S JS; Radhakrishnan, Aparna A; Vermeulen, Sita H SH; Traglia, Michela M; Gögele, Martin M; Anderson, Denise D; Broer, Linda L; Podmore, Clara C; Luan, Jian'an J; Kutalik, Zoltan Z; Sanna, Serena S; van der Meer, Peter P; Tanaka, Toshiko T; Wang, Fudi F; Westra, Harm-Jan HJ; Franke, Lude L; Mihailov, Evelin E; Milani, Lili L; Hälldin, Jonas J; Häldin, Jonas J; Winkelmann, Juliane J; Meitinger, Thomas T; Thiery, Joachim J; Peters, Annette A; Waldenberger, Melanie M; Rendon, Augusto A; Jolley, Jennifer J; Sambrook, Jennifer J; Kiemeney, Lambertus A LA; Sweep, Fred C FC; Sala, Cinzia F CF; Schwienbacher, Christine C; Pichler, Irene I; Hui, Jennie J; Demirkan, Ayse A; Isaacs, Aaron A; Amin, Najaf N; Steri, Maristella M; Waeber, Gérard G; Verweij, Niek N; Powell, Joseph E JE; Nyholt, Dale R DR; Heath, Andrew C AC; Madden, Pamela A F PA; Visscher, Peter M PM; Wright, Margaret J MJ; Montgomery, Grant W GW; Martin, Nicholas G NG; Hernandez, Dena D; Bandinelli, Stefania S; van der Harst, Pim P; Uda, Manuela M; Vollenweider, Peter P; Scott, Robert A RA; Langenberg, Claudia C; Wareham, Nicholas J NJ; , ; van Duijn, Cornelia C; Beilby, John J; Pramstaller, Peter P PP; Hicks, Andrew A AA; Ouwehand, Willem H WH; Oexle, Konrad K; Gieger, Christian C; Metspalu, Andres A; Camaschella, Clara C; Toniolo, Daniela D; Swinkels, Dorine W DW; Whitfield, John B JB
LipidSeq: a next-generation clinical resequencing panel for monogenic dyslipidemias.
Journal Of Lipid Research
Johansen, Christopher T CT; Dubé, Joseph B JB; Loyzer, Melissa N MN; MacDonald, Austin A; Carter, David E DE; McIntyre, Adam D AD; Cao, Henian H; Wang, Jian J; Robinson, John F JF; Hegele, Robert A RA
Joint linkage and association analysis with exome sequence data implicates SLC25A40 in hypertriglyceridemia.
American Journal Of Human Genetics
Rosenthal, Elisabeth A EA; Ranchalis, Jane J; Crosslin, David R DR; Burt, Amber A; Brunzell, John D JD; Motulsky, Arno G AG; Nickerson, Deborah A DA; , ; Wijsman, Ellen M EM; Jarvik, Gail P GP
Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study.
Plos Biology
Carlson, Christopher S CS; Matise, Tara C TC; North, Kari E KE; Haiman, Christopher A CA; Fesinmeyer, Megan D MD; Buyske, Steven S; Schumacher, Fredrick R FR; Peters, Ulrike U; Franceschini, Nora N; Ritchie, Marylyn D MD; Duggan, David J DJ; Spencer, Kylee L KL; Dumitrescu, Logan L; Eaton, Charles B CB; Thomas, Fridtjof F; Young, Alicia A; Carty, Cara C; Heiss, Gerardo G; Le Marchand, Loic L; Crawford, Dana C DC; Hindorff, Lucia A LA; Kooperberg, Charles L CL; ,
THOC5: a novel gene involved in HDL-cholesterol metabolism.
Journal Of Lipid Research
Keller, Maria M; Schleinitz, Dorit D; Förster, Julia J; Tönjes, Anke A; Böttcher, Yvonne Y; Fischer-Rosinsky, Antje A; Breitfeld, Jana J; Weidle, Kerstin K; Rayner, Nigel W NW; Burkhardt, Ralph R; Enigk, Beate B; Müller, Ines I; Halbritter, Jan J; Koriath, Moritz M; Pfeiffer, Andreas A; Krohn, Knut K; Groop, Leif L; Spranger, Joachim J; Stumvoll, Michael M; Kovacs, Peter P
Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.
Journal Of Lipid Research
Wu, Ying Y; Marvelle, Amanda F AF; Li, Jin J; Croteau-Chonka, Damien C DC; Feranil, Alan B AB; Kuzawa, Christopher W CW; Li, Yun Y; Adair, Linda S LS; Mohlke, Karen L KL
Impact of HDL genetic risk scores on coronary artery calcified plaque and mortality in individuals with type 2 diabetes from the Diabetes Heart Study.
Cardiovascular Diabetology
Raffield, Laura M LM; Cox, Amanda J AJ; Hsu, Fang-Chi FC; Ng, Maggie C-Y MC; Langefeld, Carl D CD; Carr, J Jeffrey JJ; Freedman, Barry I BI; Bowden, Donald W DW
Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study.
Cardiovascular Diabetology
Povel, Cécile M CM; Boer, Jolanda M A JM; Onland-Moret, N Charlotte NC; Dollé, Martijn E T ME; Feskens, Edith J M EJ; van der Schouw, Yvonne T YT
Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases.
Bmc Medical Genetics
Huhn, Stefanie S; Bevier, Melanie M; Rudolph, Anja A; Pardini, Barbara B; Naccarati, Alessio A; Hein, Rebecca R; Hoffmeister, Michael M; Vodickova, Ludmila L; Novotny, Jan J; Brenner, Hermann H; Chang-Claude, Jenny J; Hemminki, Kari K; Vodicka, Pavel P; Försti, Asta A
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.
Lancet (London, England)
Voight, Benjamin F BF; Peloso, Gina M GM; Orho-Melander, Marju M; Frikke-Schmidt, Ruth R; Barbalic, Maja M; Jensen, Majken K MK; Hindy, George G; Hólm, Hilma H; Ding, Eric L EL; Johnson, Toby T; Schunkert, Heribert H; Samani, Nilesh J NJ; Clarke, Robert R; Hopewell, Jemma C JC; Thompson, John F JF; Li, Mingyao M; Thorleifsson, Gudmar G; Newton-Cheh, Christopher C; Musunuru, Kiran K; Pirruccello, James P JP; Saleheen, Danish D; Chen, Li L; Stewart, Alexandre F R A; Schillert, Arne A; Thorsteinsdottir, Unnur U; Thorgeirsson, Gudmundur G; Anand, Sonia S; Engert, James C JC; Morgan, Thomas T; Spertus, John J; Stoll, Monika M; Berger, Klaus K; Martinelli, Nicola N; Girelli, Domenico D; McKeown, Pascal P PP; Patterson, Christopher C CC; Epstein, Stephen E SE; Devaney, Joseph J; Burnett, Mary-Susan MS; Mooser, Vincent V; Ripatti, Samuli S; Surakka, Ida I; Nieminen, Markku S MS; Sinisalo, Juha J; Lokki, Marja-Liisa ML; Perola, Markus M; Havulinna, Aki A; de Faire, Ulf U; Gigante, Bruna B; Ingelsson, Erik E; Zeller, Tanja T; Wild, Philipp P; de Bakker, Paul I W PI; Klungel, Olaf H OH; Maitland-van der Zee, Anke-Hilse AH; Peters, Bas J M BJ; de Boer, Anthonius A; Grobbee, Diederick E DE; Kamphuisen, Pieter W PW; Deneer, Vera H M VH; Elbers, Clara C CC; Onland-Moret, N Charlotte NC; Hofker, Marten H MH; Wijmenga, Cisca C; Verschuren, W M Monique WM; Boer, Jolanda M A JM; van der Schouw, Yvonne T YT; Rasheed, Asif A; Frossard, Philippe P; Demissie, Serkalem S; Willer, Cristen C; Do, Ron R; Ordovas, Jose M JM; Abecasis, Gonçalo R GR; Boehnke, Michael M; Mohlke, Karen L KL; Daly, Mark J MJ; Guiducci, Candace C; Burtt, Noël P NP; Surti, Aarti A; Gonzalez, Elena E; Purcell, Shaun S; Gabriel, Stacey S; Marrugat, Jaume J; Peden, John J; Erdmann, Jeanette J; Diemert, Patrick P; Willenborg, Christina C; König, Inke R IR; Fischer, Marcus M; Hengstenberg, Christian C; Ziegler, Andreas A; Buysschaert, Ian I; Lambrechts, Diether D; Van de Werf, Frans F; Fox, Keith A KA; El Mokhtari, Nour Eddine NE; Rubin, Diana D; Schrezenmeir, Jürgen J; Schreiber, Stefan S; Schäfer, Arne A; Danesh, John J; Blankenberg, Stefan S; Roberts, Robert R; McPherson, Ruth R; Watkins, Hugh H; Hall, Alistair S AS; Overvad, Kim K; Rimm, Eric E; Boerwinkle, Eric E; Tybjaerg-Hansen, Anne A; Cupples, L Adrienne LA; Reilly, Muredach P MP; Melander, Olle O; Mannucci, Pier M PM; Ardissino, Diego D; Siscovick, David D; Elosua, Roberto R; Stefansson, Kari K; O'Donnell, Christopher J CJ; Salomaa, Veikko V; Rader, Daniel J DJ; Peltonen, Leena L; Schwartz, Stephen M SM; Altshuler, David D; Kathiresan, Sekar S
Validation of candidate genes associated with cardiovascular risk factors in psychiatric patients.
Progress In Neuro-Psychopharmacology & Biological Psychiatry
Windemuth, Andreas A; de Leon, Jose J; Goethe, John W JW; Schwartz, Harold I HI; Woolley, Stephen S; Susce, Margaret M; Kocherla, Mohan M; Bogaard, Kali K; Holford, Theodore R TR; Seip, Richard L RL; Ruaño, Gualberto G
Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study.
Plos Genetics
Dumitrescu, Logan L; Carty, Cara L CL; Taylor, Kira K; Schumacher, Fredrick R FR; Hindorff, Lucia A LA; Ambite, José L JL; Anderson, Garnet G; Best, Lyle G LG; Brown-Gentry, Kristin K; Bůžková, Petra P; Carlson, Christopher S CS; Cochran, Barbara B; Cole, Shelley A SA; Devereux, Richard B RB; Duggan, Dave D; Eaton, Charles B CB; Fornage, Myriam M; Franceschini, Nora N; Haessler, Jeff J; Howard, Barbara V BV; Johnson, Karen C KC; Laston, Sandra S; Kolonel, Laurence N LN; Lee, Elisa T ET; MacCluer, Jean W JW; Manolio, Teri A TA; Pendergrass, Sarah A SA; Quibrera, Miguel M; Shohet, Ralph V RV; Wilkens, Lynne R LR; Haiman, Christopher A CA; Le Marchand, Loïc L; Buyske, Steven S; Kooperberg, Charles C; North, Kari E KE; Crawford, Dana C DC
The 1p13.3 LDL (C)-associated locus shows large effect sizes in young populations.
Pediatric Research
Devaney, Joseph M JM; Thompson, Paul D PD; Visich, Paul S PS; Saltarelli, William A WA; Gordon, Paul M PM; Orkunoglu-Suer, E Funda EF; Gordish-Dressman, Heather H; Harmon, Brennan T BT; Bradbury, Margaret K MK; Panchapakesan, Karuna K; Khianey, Rahul R; Hubal, Monica J MJ; Clarkson, Priscilla M PM; Pescatello, Linda S LS; Zoeller, Robert F RF; Moyna, Niall M NM; Angelopoulos, Theodore J TJ; Kraus, William E WE; Hoffman, Eric P EP
Fine-mapping in African Americans of 8 recently discovered genetic loci for plasma lipids: the Jackson Heart Study.
Circulation. Cardiovascular Genetics
Keebler, Mary E ME; Deo, Rahul C RC; Surti, Aarti A; Konieczkowski, David D; Guiducci, Candace C; Burtt, Noel N; Buxbaum, Sarah G SG; Sarpong, Daniel F DF; Steffes, Michael W MW; Wilson, James G JG; Taylor, Herman A HA; Kathiresan, Sekar S
Association of blood lipids with common DNA sequence variants at 19 genetic loci in the multiethnic United States National Health and Nutrition Examination Survey III.
Circulation. Cardiovascular Genetics
Keebler, Mary E ME; Sanders, Christopher L CL; Surti, Aarti A; Guiducci, Candace C; Burtt, Noel P NP; Kathiresan, Sekar S
Genome-wide association analyses of North American Rheumatoid Arthritis Consortium and Framingham Heart Study data utilizing genome-wide linkage results.
Bmc Proceedings
Yoo, Yun Joo YJ; Pinnaduwage, Dushanthi D; Waggott, Daryl D; Bull, Shelley B SB; Sun, Lei L
Ion mobility analysis of lipoprotein subfractions identifies three independent axes of cardiovascular risk.
Arteriosclerosis, Thrombosis, And Vascular Biology
Musunuru, Kiran K; Orho-Melander, Marju M; Caulfield, Michael P MP; Li, Shuguang S; Salameh, Wael A WA; Reitz, Richard E RE; Berglund, Göran G; Hedblad, Bo B; Engström, Gunnar G; Williams, Paul T PT; Kathiresan, Sekar S; Melander, Olle O; Krauss, Ronald M RM
A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.
Human Molecular Genetics
Hegele, Robert A RA; Ban, Matthew R MR; Hsueh, Neil N; Kennedy, Brooke A BA; Cao, Henian H; Zou, Guang Yong GY; Anand, Sonia S; Yusuf, Salim S; Huff, Murray W MW; Wang, Jian J
Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.
European Heart Journal
Murray, Anna A; Cluett, Christie C; Bandinelli, Stefania S; Corsi, Anna Maria AM; Ferrucci, Luigi L; Guralnik, Jack J; Singleton, Andrew A; Frayling, Timothy T; Melzer, David D
Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
Plos Genetics
Lowe, Jennifer K JK; Maller, Julian B JB; Pe'er, Itsik I; Neale, Benjamin M BM; Salit, Jacqueline J; Kenny, Eimear E EE; Shea, Jessica L JL; Burkhardt, Ralph R; Smith, J Gustav JG; Ji, Weizhen W; Noel, Martha M; Foo, Jia Nee JN; Blundell, Maude L ML; Skilling, Vita V; Garcia, Laura L; Sullivan, Marcia L ML; Lee, Heather E HE; Labek, Anna A; Ferdowsian, Hope H; Auerbach, Steven B SB; Lifton, Richard P RP; Newton-Cheh, Christopher C; Breslow, Jan L JL; Stoffel, Markus M; Daly, Mark J MJ; Altshuler, David M DM; Friedman, Jeffrey M JM
Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.
American Journal Of Human Genetics
Ferrucci, Luigi L; Perry, John R B JR; Matteini, Amy A; Perola, Markus M; Tanaka, Toshiko T; Silander, Kaisa K; Rice, Neil N; Melzer, David D; Murray, Anna A; Cluett, Christie C; Fried, Linda P LP; Albanes, Demetrius D; Corsi, Anna-Maria AM; Cherubini, Antonio A; Guralnik, Jack J; Bandinelli, Stefania S; Singleton, Andrew A; Virtamo, Jarmo J; Walston, Jeremy J; Semba, Richard D RD; Frayling, Timothy M TM