GRM3 c.468+8546A>G

Variant ID: 7-86403475-A-G

NM_000840.2(GRM3):c.468+8546A>G

This variant was identified in 34 publications

View GRCh38 version.




Publications:


Genetic Variants Associated with Poor Responsiveness to Sulfonylureas in Filipinos with Type 2 Diabetes Mellitus.

Journal Of The Asean Federation Of Endocrine Societies
Paz-Pacheco, Elizabeth E; Nevado, Jose J; Paz, Eva Maria Cutiongco-De La EMC; Jasul, Gabriel G; Aman, Aimee Yvonne Criselle AYC; Alejandro-Ribaya, Elizabeth Laurize EL; Francisco, Mark David MD; Guanzon, Ma Luz Vicenta MLV; Uyking-Naranjo, May M; Añonuevo-Cruz, Cecille C; Maningat, Maria Patricia Deanna MPD; Jaring, Cristina C; Nacpil-Dominguez, Paulette P; Pala-Mohamad, Aniza A; Uy-Canto, Abigail A; Quisumbing, John Paul JP; Lat, Annabelle Marie AM; Bernardo, Diane Carla DC; Mansibang, Noemie Marie NM; Ribaya, Vincent Sean VS; Calpito, Karell Jo Angelique KJA; Ferrer, Julius Patrick JP; Biwang, Jessica J; Melegrito, Jodelyn J; Deguit, Christian Deo CD; Panerio, Carlos Emmanuel CE
Publication Date: 2023

Variant appearance in text: rs6465084
PubMed Link: 37234931
Variant Present in the following documents:
  • Main text
  • JAFES-38-S1-31.pdf
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Preliminary studies on apparent mendelian psychotic disorders in consanguineous families.

Bmc Psychiatry
Kanwal, Ambreen A; Sheikh, Sohail A SA; Iftikhar, Amina A; Naz, Sadaf S; Pardo, José V JV
Publication Date: 2022-11-16

Variant appearance in text: rs6465084
PubMed Link: 36384485
Variant Present in the following documents:
  • Main text
  • 12888_2022_Article_4304.pdf
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Genes of the Glutamatergic System and Tardive Dyskinesia in Patients with Schizophrenia.

Diagnostics (Basel, Switzerland)
Fedorenko, Olga Yu OY; Paderina, Diana Z DZ; Kornetova, Elena G EG; Poltavskaya, Evgeniya G EG; Pozhidaev, Ivan V IV; Goncharova, Anastasiia A AA; Freidin, Maxim B MB; Bocharova, Anna V AV; Bokhan, Nikolay A NA; Loonen, Anton J M AJM; Ivanova, Svetlana A SA
Publication Date: 2022-06-22

Variant appearance in text: rs6465084
PubMed Link: 35885427
Variant Present in the following documents:
  • Main text
  • diagnostics-12-01521.pdf
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Pharmacogenetics of Antipsychotic Drug Treatment: Update and Clinical Implications.

Molecular Neuropsychiatry
Yoshida, Kazunari K; Müller, Daniel J DJ
Publication Date: 2020-04

Variant appearance in text: rs6465084
PubMed Link: 32399466
Variant Present in the following documents:
  • Main text
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Treatment-Resistant Schizophrenia: Genetic and Neuroimaging Correlates.

Frontiers In Pharmacology
Vita, Antonio A; Minelli, Alessandra A; Barlati, Stefano S; Deste, Giacomo G; Giacopuzzi, Edoardo E; Valsecchi, Paolo P; Turrina, Cesare C; Gennarelli, Massimo M
Publication Date: 2019

Variant appearance in text: rs6465084
PubMed Link: 31040787
Variant Present in the following documents:
  • Main text
  • fphar-10-00402.pdf
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The use of pharmacogenetic testing in patients with schizophrenia or bipolar disorder: A systematic review.

The Mental Health Clinician
Routhieaux, Melanie M; Keels, Jessica J; Tillery, Erika E EE
Publication Date: 2018-11

Variant appearance in text: rs6465084
PubMed Link: 30397571
Variant Present in the following documents:
  • Main text
  • i2168-9709-8-6-294.pdf
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Host-parasite interaction associated with major mental illness.

Molecular Psychiatry
Kano, Shin-Ichi SI; Hodgkinson, Colin A CA; Jones-Brando, Lorraine L; Eastwood, Sharon S; Ishizuka, Koko K; Niwa, Minae M; Choi, Eric Y EY; Chang, Daniel J DJ; Chen, Yian Y; Velivela, Swetha D SD; Leister, Flora F; Wood, Joel J; Chowdari, Kodavali K; Ducci, Francesca F; Caycedo, Daniel A DA; Heinz, Elizabeth E; Newman, Emily R ER; Cascella, Nicola N; Mortensen, Preben B PB; Zandi, Peter P PP; Dickerson, Faith F; Nimgaonkar, Vishwajit V; Goldman, David D; Harrison, Paul J PJ; Yolken, Robert H RH; Sawa, Akira A
Publication Date: 2020-01

Variant appearance in text: rs6465084
PubMed Link: 30127472
Variant Present in the following documents:
  • Main text
  • nihms-976890.pdf
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Genome-Wide Supported Risk Variants in MIR137, CACNA1C, CSMD1, DRD2, and GRM3 Contribute to Schizophrenia Susceptibility in Pakistani Population.

Psychiatry Investigation
Fatima, Ambrin A; Farooq, Muhammad M; Abdullah, Uzma U; Tariq, Muhammad M; Mustafa, Tanveer T; Iqbal, Muhammad M; Tommerup, Niels N; Mahmood Baig, Shahid S
Publication Date: 2017-09

Variant appearance in text: rs6465084
PubMed Link: 29042896
Variant Present in the following documents:
  • Main text
  • pi-14-687.pdf
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Meta-analysis supports GWAS-implicated link between GRM3 and schizophrenia risk.

Translational Psychiatry
Saini, S M SM; Mancuso, S G SG; Mostaid, Md S MS; Liu, C C; Pantelis, C C; Everall, I P IP; Bousman, C A CA
Publication Date: 2017-08-08

Variant appearance in text: rs6465084
PubMed Link: 28786982
Variant Present in the following documents:
  • Main text
  • tp2017172a.pdf
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Relationship of Genetic Variants With Procedural Pain, Anxiety, and Distress in Children.

Biological Research For Nursing
Ersig, Anne L AL; Schutte, Debra L DL; Standley, Jennifer J; Leslie, Elizabeth E; Zimmerman, Bridget B; Kleiber, Charmaine C; Hanrahan, Kirsten K; Murray, Jeffrey C JC; McCarthy, Ann Marie AM
Publication Date: 2017-05

Variant appearance in text: rs6465084
PubMed Link: 28413930
Variant Present in the following documents:
  • Main text
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Genetic Consideration of Schizotypal Traits: A Review.

Frontiers In Psychology
Walter, Emma E EE; Fernandez, Francesca F; Snelling, Mollie M; Barkus, Emma E
Publication Date: 2016

Variant appearance in text: rs6465084
PubMed Link: 27895608
Variant Present in the following documents:
  • Main text
  • fpsyg-07-01769.pdf
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Genetic Studies on the Tripartite Glutamate Synapse in the Pathophysiology and Therapeutics of Mood Disorders.

Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
de Sousa, Rafael T RT; Loch, Alexandre A AA; Carvalho, André F AF; Brunoni, André R AR; Haddad, Marie Reine MR; Henter, Ioline D ID; Zarate, Carlos A CA; Machado-Vieira, Rodrigo R
Publication Date: 2017-03

Variant appearance in text: rs6465084
PubMed Link: 27510426
Variant Present in the following documents:
  • Main text
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The Role of Metabotropic Glutamate Receptor Genes in Schizophrenia.

Current Neuropharmacology
Maj, Carlo C; Minelli, Alessandra A; Giacopuzzi, Edoardo E; Sacchetti, Emilio E; Gennarelli, Massimo M
Publication Date: 2016

Variant appearance in text: rs6465084
PubMed Link: 27296644
Variant Present in the following documents:
  • Main text
  • CN-14-540.pdf
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Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings.

Progress In Molecular Biology And Translational Science
Bell, Richard L RL; Hauser, Sheketha R SR; McClintick, Jeanette J; Rahman, Shafiqur S; Edenberg, Howard J HJ; Szumlinski, Karen K KK; McBride, William J WJ
Publication Date: 2016

Variant appearance in text: rs6465084
PubMed Link: 26809998
Variant Present in the following documents:
  • Main text
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Association of metabotropic glutamate receptor 3 gene polymorphisms with schizophrenia risk: evidence from a meta-analysis.

Neuropsychiatric Disease And Treatment
Yang, Xiaoqin X; Wang, Guiping G; Wang, Yaodong Y; Yue, Xia X
Publication Date: 2015

Variant appearance in text: rs6465084
PubMed Link: 25848280
Variant Present in the following documents:
  • Main text
  • ndt-11-823.pdf
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Perspectives on the mGluR2/3 agonists as a therapeutic target for schizophrenia: Still promising or a dead end?

Progress In Neuro-Psychopharmacology & Biological Psychiatry
Li, Meng-Lin ML; Hu, Xi-Quan XQ; Li, Feng F; Gao, Wen-Jun WJ
Publication Date: 2015-07-03

Variant appearance in text: rs6465084
PubMed Link: 25724760
Variant Present in the following documents:
  • Main text
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Brain proton magnetic resonance spectroscopy of alcohol use disorders.

Handbook Of Clinical Neurology
Meyerhoff, Dieter J DJ
Publication Date: 2014

Variant appearance in text: rs6465084
PubMed Link: 25307583
Variant Present in the following documents:
  • Main text
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Pharmacogenetic associations of the type-3 metabotropic glutamate receptor (GRM3) gene with working memory and clinical symptom response to antipsychotics in first-episode schizophrenia.

Psychopharmacology
Bishop, Jeffrey R JR; Reilly, James L JL; Harris, Margret S H MS; Patel, Shitalben R SR; Kittles, Rick R; Badner, Judith A JA; Prasad, Konasale M KM; Nimgaonkar, Vishwajit L VL; Keshavan, Matcheri S MS; Sweeney, John A JA
Publication Date: 2015-01

Variant appearance in text: rs6465084
PubMed Link: 25096017
Variant Present in the following documents:
  • Main text
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Association of variants in DRD2 and GRM3 with motor and cognitive function in first-episode psychosis.

European Archives Of Psychiatry And Clinical Neuroscience
Lencer, Rebekka R; Bishop, Jeffrey R JR; Harris, Margret S H MS; Reilly, James L JL; Patel, Shitalben S; Kittles, Rick R; Prasad, Konasale M KM; Nimgaonkar, Vishwajit L VL; Keshavan, Matcheri S MS; Sweeney, John A JA
Publication Date: 2014-06

Variant appearance in text: rs6465084
PubMed Link: 24682224
Variant Present in the following documents:
  • Main text
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Metabotropic glutamate receptor 3 is associated with heroin dependence but not depression or schizophrenia in a Chinese population.

Plos One
Jia, Wei W; Zhang, Rui R; Wu, Bin B; Dai, Zun-xiao ZX; Zhu, Yong-sheng YS; Li, Ping-ping PP; Zhu, Feng F
Publication Date: 2014

Variant appearance in text: rs6465084
PubMed Link: 24498053
Variant Present in the following documents:
  • Main text
  • pone.0087247.pdf
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A population-based study of genetic variation and psychotic experiences in adolescents.

Schizophrenia Bulletin
Zammit, Stanley S; Hamshere, Marian M; Dwyer, Sarah S; Georgiva, Lyudmila L; Timpson, Nic N; Moskvina, Valentina V; Richards, Alexander A; Evans, David M DM; Lewis, Glyn G; Jones, Peter P; Owen, Michael J MJ; O'Donovan, Michael C MC
Publication Date: 2014-11

Variant appearance in text: rs6465084
PubMed Link: 24174267
Variant Present in the following documents:
  • Main text
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Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate levels and neurocognition in non-smoking, active alcoholics.

Behavioral And Brain Functions : Bbf
Xia, Yan Y; Ma, Dongying D; Hu, Jian J; Tang, Chunling C; Wu, Zheng Z; Liu, Lei L; Xin, Feng F
Publication Date: 2012-08-21

Variant appearance in text: rs6465084
PubMed Link: 22909248
Variant Present in the following documents:
  • Main text
  • 1744-9081-8-42.pdf
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Effects of metabotropic glutamate receptor 3 genotype on phonetic mismatch negativity.

Plos One
Kawakubo, Yuki Y; Suga, Motomu M; Tochigi, Mamoru M; Yumoto, Masato M; Itoh, Kenji K; Sasaki, Tsukasa T; Kano, Yukiko Y; Kasai, Kiyoto K
Publication Date: 2011

Variant appearance in text: rs6465084
PubMed Link: 22022368
Variant Present in the following documents:
  • Main text
  • pone.0024929.pdf
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No Association Between GRM3 and Japanese Methamphetamine-Induced Psychosis.

Current Neuropharmacology
Tsunoka, Tomoko T; Kishi, Taro T; Ikeda, Masashi M; Kitajima, Tsuyoshi T; Yamanouchi, Yoshio Y; Kinoshita, Yoko Y; Kawashima, Kunihiro K; Okochi, Tomo T; Okumura, Takenori T; Inada, Toshiya T; Ujike, Hiroshi H; Yamada, Mitsuhiko M; Uchimura, Naohisa N; Sora, Ichiro I; Iyo, Masaomi M; Ozaki, Norio N; Iwata, Nakao N
Publication Date: 2011-03

Variant appearance in text: rs6465084
PubMed Link: 21886583
Variant Present in the following documents:
  • Main text
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Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia.

The American Journal Of Psychiatry
Greenwood, Tiffany A TA; Lazzeroni, Laura C LC; Murray, Sarah S SS; Cadenhead, Kristin S KS; Calkins, Monica E ME; Dobie, Dorcas J DJ; Green, Michael F MF; Gur, Raquel E RE; Gur, Ruben C RC; Hardiman, Gary G; Kelsoe, John R JR; Leonard, Sherry S; Light, Gregory A GA; Nuechterlein, Keith H KH; Olincy, Ann A; Radant, Allen D AD; Schork, Nicholas J NJ; Seidman, Larry J LJ; Siever, Larry J LJ; Silverman, Jeremy M JM; Stone, William S WS; Swerdlow, Neal R NR; Tsuang, Debby W DW; Tsuang, Ming T MT; Turetsky, Bruce I BI; Freedman, Robert R; Braff, David L DL
Publication Date: 2011-09

Variant appearance in text: rs6465084
PubMed Link: 21498463
Variant Present in the following documents:
  • Main text
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Association between type-three metabotropic glutamate receptor gene (GRM3) variants and symptom presentation in treatment refractory schizophrenia.

Human Psychopharmacology
Bishop, Jeffrey R JR; Miller, Del D del D; Ellingrod, Vicki L VL; Holman, Timothy T
Publication Date: 2011-01

Variant appearance in text: rs6465084
PubMed Link: 21344500
Variant Present in the following documents:
  • Main text
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Imaging genetics of structural brain connectivity and neural integrity markers.

Neuroimage
Marenco, Stefano S; Radulescu, Eugenia E
Publication Date: 2010-11-15

Variant appearance in text: rs6465084
PubMed Link: 19932755
Variant Present in the following documents:
  • Main text
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Candidate genes and their interactions with other genetic/environmental risk factors in the etiology of schizophrenia.

Brain Research Bulletin
Prasad, K M KM; Talkowski, M E ME; Chowdari, K V KV; McClain, L L; Yolken, R H RH; Nimgaonkar, V L VL
Publication Date: 2010-09-30

Variant appearance in text: rs6465084
PubMed Link: 19729054
Variant Present in the following documents:
  • Main text
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Group II metabotropic glutamate receptors and schizophrenia.

Cellular And Molecular Life Sciences : Cmls
Moreno, José L JL; Sealfon, Stuart C SC; González-Maeso, Javier J
Publication Date: 2009-12

Variant appearance in text: rs6465084
PubMed Link: 19707855
Variant Present in the following documents:
  • Main text
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Executive function, neural circuitry, and genetic mechanisms in schizophrenia.

Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
Eisenberg, Daniel Paul DP; Berman, Karen Faith KF
Publication Date: 2010-01

Variant appearance in text: rs6465084
PubMed Link: 19693005
Variant Present in the following documents:
  • Main text
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Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia.

The International Journal Of Neuroscience
Ghose, Subroto S; Crook, Jeremy M JM; Bartus, Cynthia L CL; Sherman, Thomas G TG; Herman, Mary M MM; Hyde, Thomas M TM; Kleinman, Joel E JE; Akil, Mayada M
Publication Date: 2008-11

Variant appearance in text: rs6465084
PubMed Link: 18853337
Variant Present in the following documents:
  • Main text
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Epistasis between catechol-O-methyltransferase and type II metabotropic glutamate receptor 3 genes on working memory brain function.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Tan, Hao-Yang HY; Chen, Qiang Q; Sust, Steven S; Buckholtz, Joshua W JW; Meyers, John D JD; Egan, Michael F MF; Mattay, Venkata S VS; Meyer-Lindenberg, Andreas A; Weinberger, Daniel R DR; Callicott, Joseph H JH
Publication Date: 2007-07-24

Variant appearance in text: rs6465084
PubMed Link: 17636131
Variant Present in the following documents:
  • Main text
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Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate measures in the dorsolateral prefrontal cortex.

The American Journal Of Psychiatry
Marenco, Stefano S; Steele, Sonya U SU; Egan, Michael F MF; Goldberg, Terry E TE; Straub, Richard E RE; Sharrief, Anjail Z AZ; Weinberger, Daniel R DR
Publication Date: 2006-04

Variant appearance in text: rs6465084
PubMed Link: 16585454
Variant Present in the following documents:
  • Main text
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No evidence for association between polymorphisms in GRM3 and schizophrenia.

Bmc Psychiatry
Norton, Nadine N; Williams, Hywel J HJ; Dwyer, Sarah S; Ivanov, Dobril D; Preece, Anna C AC; Gerrish, Amy A; Williams, Nigel M NM; Yerassimou, Pamela P; Zammit, Stanley S; O'Donovan, Michael C MC; Owen, Michael J MJ
Publication Date: 2005-05-13

Variant appearance in text: rs6465084
PubMed Link: 15892884
Variant Present in the following documents:
  • Main text
  • 1471-244X-5-23.pdf
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