Variant ID: 7-87138645-A-G

NM_000927.4(ABCB1):c.3435T>C;(p.Ile1145Ile)

This variant was identified in 730 publications




Publications:


Combinations of common SNPs of the transporter gene ABCB1 influence apparent bioavailability, but not renal elimination of oral digoxin.

Scientific Reports
CH Hsin, MS Stoffel, M Gazzaz, E Schaeffeler, M Schwab, U Fuhr, M Taubert
Publication Date: 2020-07-27

Variant appearance in text: N/A
PMID: 32719417
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CYP2C19, PON1, and ABCB1 gene polymorphisms in Han and Uygur populations with coronary artery disease in Northwestern Xinjiang, China, From 2014 Through 2019.

Medicine
T Wang, T Zhao, S Bao, L Jia, J Feng, A Yu, L Sun, X Guo, H Li, L Yu
Publication Date: 2020-07-17

Variant appearance in text: rs1045642
PMID: 32702814
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Polymorphisms within methotrexate pathway genes: Relationship between plasma methotrexate levels, toxicity experienced and outcome in pediatric acute lymphoblastic leukemia.

Iranian Journal Of Basic Medical Sciences
MA Esmaili, A Kazemi, M Faranoush, H Mellstedt, F Zaker, M Safa, N Mehrvar, MR Rezvany
Publication Date: 2020-06

Variant appearance in text: rs1045642
PMID: 32695297
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ABCB1 Genetic Variants as Predictors of Irinotecan-Induced Severe Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients.

Frontiers In Pharmacology
P Riera, A Artigas-Baleri, J Salazar, A Sebio, AC Virgili, MJ Arranz, D Páez
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32695000
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Genetic variation in the farnesoid X-receptor predicts Crohn's disease severity in female patients.

Scientific Reports
A Wilson, Q Wang, AA Almousa, LE Jansen, YH Choi, UI Schwarz, RB Kim
Publication Date: 2020-07-16

Variant appearance in text: N/A
PMID: 32678214
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Genetic Polymorphisms Associated with Rheumatoid Arthritis Development and Antirheumatic Therapy Response.

International Journal Of Molecular Sciences
DS Mikhaylenko, MV Nemtsova, IV Bure, EB Kuznetsova, EA Alekseeva, VV Tarasov, AN Lukashev, MI Beloukhova, AA Deviatkin, AA Zamyatnin
Publication Date: 2020-07-11

Variant appearance in text: rs1045642
PMID: 32664585
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Gene Polymorphisms Affecting the Pharmacokinetics and Pharmacodynamics of Donepezil Efficacy.

Frontiers In Pharmacology
J Lu, X Wang, L Wan, J Fu, Y Huo, Y Zhao, C Guo
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32636753
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Pharmacogenomics of Hypertension Treatment.

International Journal Of Molecular Sciences
J Rysz, B Franczyk, M Rysz-Górzyńska, A Gluba-Brzózka
Publication Date: 2020-07-01

Variant appearance in text: rs1045642
PMID: 32630286
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Pharmacogenomics and Pharmacogenetics in Osteosarcoma: Translational Studies and Clinical Impact.

International Journal Of Molecular Sciences
CM Hattinger, MP Patrizio, S Luppi, M Serra
Publication Date: 2020-06-30

Variant appearance in text: rs1045642
PMID: 32629971
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Initial Dosage Recommendation for Sirolimus in Children With Tuberous Sclerosis Complex.

Frontiers In Pharmacology
DD Wang, X Chen, H Xu, ZP Li
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32595509
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Molecular Bases of Drug Resistance in Hepatocellular Carcinoma.

Cancers
JJG Marin, RIR Macias, MJ Monte, MR Romero, M Asensio, A Sanchez-Martin, C Cives-Losada, AG Temprano, R Espinosa-Escudero, M Reviejo, LH Bohorquez, O Briz
Publication Date: 2020-06-23

Variant appearance in text: rs1045642
PMID: 32585893
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MDR1 Gene Polymorphisms and Its Association With Expression as a Clinical Relevance in Terms of Response to Chemotherapy and Prognosis in Ovarian Cancer.

Frontiers In Genetics
A Haque, KHW Sait, Q Alam, MZ Alam, N Anfinan, AWN Wali, M Rasool
Publication Date: 2020

Variant appearance in text: N/A
PMID: 32528530
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The atorvastatin metabolic phenotype shift is influenced by interaction of drug-transporter polymorphisms in Mexican population: results of a randomized trial.

Scientific Reports
RBR León-Cachón, AD Bamford, I Meester, HA Barrera-Saldaña, M Gómez-Silva, MFG Bustos
Publication Date: 2020-06-01

Variant appearance in text: N/A
PMID: 32483134
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Association of NUDT15*3 and FPGS 2572C>T Variants with the Risk of Early Hematologic Toxicity During 6-MP and Low-Dose Methotrexate-Based Maintenance Therapy in Indian Patients with Acute Lymphoblastic Leukemia.

Genes
S Kodidela, P Dorababu, DN Thakkar, B Dubashi, R Sundaram, N Muralidharan, RP Nidanapu, A Aribandi, SC Pradhan, CRS Uppugunduri
Publication Date: 2020-05-28

Variant appearance in text: ABCB1: 3435T>C; rs1045642
PMID: 32481505
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Polymorphisms of Drug-Metabolizing Enzymes and Transporters Contribute to the Individual Variations of Erlotinib Steady State Trough Concentration, Treatment Outcomes, and Adverse Reactions in Epidermal Growth Factor Receptor-Mutated Non-Small Cell Lung Cancer Patients.

Frontiers In Pharmacology
D Liao, Z Liu, Y Zhang, N Liu, D Yao, L Cao, Y Chen, Y Fu, N Yang, D Xiang
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32457635
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Possible Genetic Determinants of Response to Phenytoin in a Group of Colombian Patients With Epilepsy.

Frontiers In Pharmacology
CA Calderon-Ospina, JM Galvez, C López-Cabra, N Morales, CM Restrepo, J Rodríguez, FA Aristizábal-Gutiérrez, A Velez-van-Meerbeke, P Laissue, DJ Fonseca-Mendoza
Publication Date: 2020

Variant appearance in text: ABCB1: 3435T>C; rs1045642
PMID: 32457604
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Are gene polymorphisms related to adverse events of methotrexate in patients with rheumatoid arthritis? A retrospective cohort study based on an updated meta-analysis.

Therapeutic Advances In Chronic Disease
J Huang, H Fan, Q Qiu, K Liu, S Lv, J Li, H Yang, X Shu, Y Xu, X Lu, C Lu, Y Zhang, C Xiao
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32426102
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The effect of ABCB1 polymorphism on sirolimus in renal transplant recipients: a meta-analysis.

Translational Andrology And Urology
S Shao, L Hu, Z Han, K Hou, H Fang, G Zhang, Y Feng, L Huang
Publication Date: 2020-04

Variant appearance in text: N/A
PMID: 32420174
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Positive detection of SARS-CoV-2 combined HSV1 and HHV6B virus nucleic acid in tear and conjunctival secretions of a non-conjunctivitis COVID-19 patient with obstruction of common lacrimal duct.

Acta Ophthalmologica
Y Hu, T Chen, M Liu, L Zhang, F Wang, S Zhao, H Liu, H Xia, Y Wang, L Li
Publication Date: 2020-05-14

Variant appearance in text: N/A
PMID: 32406606
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Use of pharmacogenomics in elderly patients treated for cardiovascular diseases.

Croatian Medical Journal
N Božina, M Vrkić Kirhmajer, L Šimičević, L Ganoci, N Mirošević Skvrce, I Klarica Domjanović, I Merćep
Publication Date: 2020-04-30

Variant appearance in text: rs1045642
PMID: 32378381
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The influence of genetic polymorphisms in drug metabolism enzymes and transporters on the pharmacokinetics of different fluvastatin formulations.

Asian Journal Of Pharmaceutical Sciences
Q Xiang, W Wu, N Zhao, C Li, J Xu, L Ma, X Zhang, Q Xie, Z Zhang, J Wang, W Xu, X Zhao, Y Cui
Publication Date: 2020-03

Variant appearance in text: rs1045642
PMID: 32373204
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Pharmacogenomics of Cognitive Dysfunction and Neuropsychiatric Disorders in Dementia.

International Journal Of Molecular Sciences
R Cacabelos
Publication Date: 2020-04-26

Variant appearance in text: rs1045642
PMID: 32357528
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Association of Genetic Polymorphisms With Afatinib-induced Diarrhoea.

In Vivo (Athens, Greece)
R Sogawa, C Nakashima, T Nakamura, K Takeuchi, S Kimura, K Komiya, Y Narisawa, S Kimura, N Sueoka-Aragane
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32354939
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Toxicity and Pharmacogenomic Biomarkers in Breast Cancer Chemotherapy.

Frontiers In Pharmacology
ZN Al-Mahayri, GP Patrinos, BR Ali
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32351390
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Genetic polymorphisms of pharmacogenomic VIP variants in the Dai population from Yunnan province.

Molecular Genetics & Genomic Medicine
Y Cheng, R Dai, W Chen, Q Li, C Zhang, T Yang
Publication Date: 2020-04-29

Variant appearance in text: rs1045642
PMID: 32347657
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A Pharmacogenetically Guided Acenocoumarol Dosing Algorithm for Chilean Patients: A Discovery Cohort Study.

Frontiers In Pharmacology
A Roco, E Nieto, M Suárez, M Rojo, MP Bertoglia, G Verón, F Tamayo, A Arredondo, D Cruz, J Muñoz, G Bravo, P Salas, F Mejías, G Godoy, P Véliz, LA Quiñones
Publication Date: 2020

Variant appearance in text: ABCB1: Ile1145Ile; rs1045642
PMID: 32327994
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Interindividual Variability of Apixaban Plasma Concentrations: Influence of Clinical and Genetic Factors in a Real-Life Cohort of Atrial Fibrillation Patients.

Genes
AN Roşian, ŞH Roşian, B Kiss, MG Ştefan, AP Trifa, CD Ober, O Anchidin, AD Buzoianu
Publication Date: 2020-04-17

Variant appearance in text: P-gp: Ile1145Ile; rs1045642
PMID: 32316515
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The impact of ABCB1 gene polymorphism and its expression on non-small-cell lung cancer development, progression and therapy - preliminary report.

Scientific Reports
I Zawadzka, A Jeleń, J Pietrzak, M Żebrowska-Nawrocka, K Michalska, D Szmajda-Krygier, M Mirowski, M Łochowski, J Kozak, E Balcerczak
Publication Date: 2020-04-10

Variant appearance in text: N/A
PMID: 32277145
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Genetic Polymorphisms and Platinum-Based Chemotherapy-Induced Toxicities in Patients With Lung Cancer: A Systematic Review and Meta-Analysis.

Frontiers In Oncology
W Liu, Y Wang, J Luo, H Yuan, Z Luo
Publication Date: 2019

Variant appearance in text: rs1045642
PMID: 32257953
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Importance of genetic polymorphisms in liver transplantation outcomes.

World Journal Of Gastroenterology
T Kelava, P Turcic, A Markotic, A Ostojic, D Sisl, A Mrzljak
Publication Date: 2020-03-28

Variant appearance in text: rs1045642
PMID: 32256016
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Impact of genetic variants of ABCB1, APOB, CAV1, and NAMPT on susceptibility to pancreatic ductal adenocarcinoma in Chinese patients.

Molecular Genetics & Genomic Medicine
B Li, C Zhang, J Wang, M Zhang, C Liu, Z Chen
Publication Date: 2020-04-03

Variant appearance in text: rs1045642
PMID: 32243098
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Functionally Significant Coumarin-Related Variant Alleles and Time to Therapeutic Range in Chilean Cardiovascular Patients.

Clinical And Applied Thrombosis/Hemostasis : Official Journal Of The International Academy Of Clinical And Applied Thrombosis/Hemostasis
M Rojo, AM Roco, M Suarez, MA Lavanderos, G Verón, MP Bertoglia, A Arredondo, E Nieto, JC Rubilar, F Tamayo, D Cruz, J Muñoz, G Bravo, P Salas, F Mejías, P Véliz, G Godoy, NM Varela, G Llull, LA Quiñones
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32228310
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A Functional Synonymous Variant in PDGFRA Is Associated with Better Survival in Acral Melanoma.

Journal Of Cancer
J Dai, L Yang, T Xu, L Si, C Cui, X Sheng, Z Chi, L Mao, B Lian, B Tang, X Bai, L Zhou, S Li, X Wang, X Yan, Y Kong, J Guo
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32226509
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Ethnogeographic and inter-individual variability of human ABC transporters.

Human Genetics
Q Xiao, Y Zhou, VM Lauschke
Publication Date: 2020-03-23

Variant appearance in text: ABCB1: I1145I; rs1045642
PMID: 32206879
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Association between eight P-glycoprotein (MDR1/ABCB1) gene polymorphisms and antipsychotic drug-induced hyperprolactinemia.

British Journal Of Clinical Pharmacology
LM Geers, IV Pozhidaev, SA Ivanova, MB Freidin, AF Schmidt, D Cohen, AS Boiko, DZ Paderina, OY Fedorenko, AV Semke, NA Bokhan, B Wilffert, JGW Kosterink, DJ Touw, AJM Loonen
Publication Date: 2020-03-21

Variant appearance in text: rs1045642
PMID: 32198935
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Perplexing Role of P-Glycoprotein in Tumor Microenvironment.

Frontiers In Oncology
K Robinson, V Tiriveedhi
Publication Date: 2020

Variant appearance in text: P-gp: Ile1145Ile; rs1045642
PMID: 32195185
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Pharmacogenetic-Whole blood and intracellular pharmacokinetic-Pharmacodynamic (PG-PK2-PD) relationship of tacrolimus in liver transplant recipients.

Plos One
C Tron, JB Woillard, P Houssel-Debry, V David, C Jezequel, M Rayar, D Balakirouchenane, B Blanchet, J Debord, A Petitcollin, M Roussel, MC Verdier, E Bellissant, F Lemaitre
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32163483
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CYP2C19*17 May Increase the Risk of Death Among Patients with an Acute Coronary Syndrome and Non-Valvular Atrial Fibrillation Who Receive Clopidogrel and Rivaroxaban.

Pharmacogenomics And Personalized Medicine
DA Sychev, OA Baturina, KB Mirzaev, E Rytkin, DV Ivashchenko, DA Andreev, KA Ryzhikova, EA Grishina, PO Bochkov, RV Shevchenko
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32158254
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ABCB1 variants C3435T and T129C are not associated with colorectal cancer risk.

African Health Sciences
AM Al Qahtani, AB Al-Ghafari, HA Al Doghaither, AH Alzahrani, UM Omar, SA Rahimulddin
Publication Date: 2019-09

Variant appearance in text: N/A
PMID: 32127820
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Impact of Population and Pharmacogenetics Variations on Efavirenz Pharmacokinetics and Immunologic Outcomes During Anti-Tuberculosis Co-Therapy: A Parallel Prospective Cohort Study in Two Sub-Sahara African Populations.

Frontiers In Pharmacology
S Mugusi, A Habtewold, E Ngaimisi, W Amogne, G Yimer, O Minzi, E Makonnen, C Sudfeld, J Burhenne, E Aklillu
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32116703
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Association between ABCB1 (3435C>T) polymorphism and susceptibility of colorectal cancer: A meta-analysis.

Medicine
LL Han, BL Zuo, WL Cai, ZN Guo, BH Tong, HL Wei, Z Zhu, GY Li
Publication Date: 2020-02

Variant appearance in text: N/A
PMID: 32080102
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The association of genetic polymorphisms in CYP1A2, UGT1A4, and ABCB1 with autonomic nervous system dysfunction in schizophrenia patients treated with olanzapine.

Bmc Psychiatry
S Hattori, A Suda, M Miyauchi, Y Shiraishi, T Saeki, T Fukushima, M Fujibayashi, N Tsujita, C Ishii, N Ishii, T Moritani, Y Saigusa, I Kishida
Publication Date: 2020-02-18

Variant appearance in text: rs1045642
PMID: 32070304
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The MDR1/ABCB1 gene rs 1045642 polymorphism in colorectal cancer.

Archives Of Medical Science : Ams
B Mrozikiewicz-Rakowska, M Malinowski, P Nehring, J Bartkowiak-Wieczorek, A Bogacz, E Żurawińska-Grzelka, P Krasnodębski, J Muszyński, T Grzela, A Przybyłkowski, L Czupryniak
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32051713
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The analysis of pharmacokinetic and pharmacogenomic impact on gefitinib efficacy in advanced non-small cell lung cancer patients: results from a prospective cohort study.

Annals Of Translational Medicine
Y Ma, S Xin, Q Lin, W Zhuang, Y Zhao, X Zhu, H Zhao, M Huang, X Xun, Y Yang, W Fang, L Zhang, X Wang
Publication Date: 2019-12

Variant appearance in text: rs1045642
PMID: 32042822
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Association between ABCB1, ABCG2 carrier protein and COX-2 enzyme gene polymorphisms and breast cancer risk in a Turkish population.

Saudi Pharmaceutical Journal : Spj : The Official Publication Of The Saudi Pharmaceutical Society
KP Zeliha, O Dilek, O Ezgi, K Halil, U Cihan, O Gul
Publication Date: 2020-02

Variant appearance in text: N/A
PMID: 32042261
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Single nucleotide polymorphisms associated with postoperative inadequate analgesia after single-port VATS in Chinese population.

Bmc Anesthesiology
X Xing, Y Bai, K Sun, M Yan
Publication Date: 2020-02-05

Variant appearance in text: rs1045642
PMID: 32024468
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Pharmacogene Variation in Thai Plasmodium vivax Relapse Patients Treated with a Combination of Primaquine and Chloroquine.

Pharmacogenomics And Personalized Medicine
M Chamnanphon, A Gaedigk, A Puangpetch, E Pasomsub, W Chantratita, RJ Longley, J Sattabongkot, P Chariyavilaskul, C Sukasem
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32021383
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Effects of AQP4 and KCNJ10 Gene Polymorphisms on Drug Resistance and Seizure Susceptibility in Chinese Han Patients with Focal Epilepsy.

Neuropsychiatric Disease And Treatment
H Zhu, M Zhang, Y Fu, H Long, W Xiao, L Feng, B Xiao, L Zhou
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 32021205
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Association study of genetic polymorphisms in proteins involved in oseltamivir transport, metabolism, and interactions with adverse reactions in Mexican patients with acute respiratory diseases.

The Pharmacogenomics Journal
M Bermúdez de León, RBR León-Cachón, B Silva-Ramírez, RN González-Ríos, B Escobedo-Guajardo, R Leyva-Parra, B Tovar-Cisneros, E González-González, A Alvarado-Díaz, O Vázquez-Monsiváis, V Mata-Tijerina, L Puente-Lugo, E Álvarez-Galván, MJ Currás-Tuala, M Aguado-Barrera, F Castorena-Torres, JM Alcocer-González, G Elizondo, AM Salinas-Martínez
Publication Date: 2020-02-04

Variant appearance in text: rs1045642
PMID: 32015454
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Influence of Germline Genetics on Tacrolimus Pharmacokinetics and Pharmacodynamics in Allogeneic Hematopoietic Stem Cell Transplant Patients.

International Journal Of Molecular Sciences
J Zhu, T Patel, JA Miller, CD Torrice, M Aggarwal, MR Sketch, MD Alexander, PM Armistead, JM Coghill, T Grgic, KJ Jamieson, JR Ptachcinski, ML Riches, JS Serody, JL Schmitz, JR Shaw, TC Shea, O Suzuki, BG Vincent, WA Wood, KV Rao, T Wiltshire, ET Weimer, DJ Crona
Publication Date: 2020-01-29

Variant appearance in text: rs1045642
PMID: 32013193
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Heterogeneity in the distribution of 159 drug-response related SNPs in world populations and their genetic relatedness.

Plos One
T Ahsan, NJ Urmi, AA Sajib
Publication Date: 2020

Variant appearance in text: rs1045642
PMID: 31971968
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The Association between ABCB1 C1236T/C3435T SNPs and H. pylori Infection among Jordanians.

Genes
MN BaniHani, OF Khabour, KH Alzoubi, NA Bashir, MAK Shakhatreh, SH Sabi, N Alrabadi
Publication Date: 2020-01-05

Variant appearance in text: N/A
PMID: 31948121
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Pharmacogenomic Characterization in Bipolar Spectrum Disorders.

Pharmaceutics
S Fortinguerra, V Sorrenti, P Giusti, M Zusso, A Buriani
Publication Date: 2019-12-21

Variant appearance in text: rs1045642
PMID: 31877761
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ABCB1 Polymorphisms and Drug-Resistant Epilepsy in a Tunisian Population.

Disease Markers
M Chouchi, H Klaa, I Ben-Youssef Turki, L Hila
Publication Date: 2019

Variant appearance in text: N/A
PMID: 31871496
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Statin-Related Myotoxicity: A Comprehensive Review of Pharmacokinetic, Pharmacogenomic and Muscle Components.

Journal Of Clinical Medicine
RM Turner, M Pirmohamed
Publication Date: 2019-12-20

Variant appearance in text: rs1045642
PMID: 31861911
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Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

Gut
Z Montazeri, X Li, C Nyiraneza, X Ma, M Timofeeva, V Svinti, X Meng, Y He, Y Bo, S Morgan, S Castellví-Bel, C Ruiz-Ponte, C Fernández-Rozadilla, Á Carracedo, A Castells, T Bishop, D Buchanan, MA Jenkins, TO Keku, A Lindblom, FJB van Duijnhoven, A Wu, SM Farrington, MG Dunlop, H Campbell, E Theodoratou, W Zheng, J Little
Publication Date: 2019-12-09

Variant appearance in text: rs1045642
PMID: 31818908
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The Role of Single-Nucleotide Polymorphisms in Pituitary Adenomas Tumorigenesis.

Cancers
SS Shah, MK Aghi
Publication Date: 2019-12-09

Variant appearance in text: rs1045642
PMID: 31818039
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Drug-drug-gene interactions and adverse drug reactions.

The Pharmacogenomics Journal
MA Malki, ER Pearson
Publication Date: 2019-12-03

Variant appearance in text: rs1045642
PMID: 31792369
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Pharmacogenetics of amfepramone in healthy Mexican subjects reveals potential markers for tailoring pharmacotherapy of obesity: results of a randomised trial.

Scientific Reports
M Gómez-Silva, E Piñeyro-Garza, R Vargas-Zapata, ME Gamino-Peña, A León-García, MB de León, A Llerena, RBR León-Cachón
Publication Date: 2019-11-28

Variant appearance in text: rs1045642
PMID: 31780765
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Both CYP2C19 and PON1 Q192R Genotypes Influence Platelet Response to Clopidogrel by Thrombelastography in Patients with Acute Coronary Syndrome.

Cardiovascular Therapeutics
W Peng, X Shi, X Xu, Y Lin
Publication Date: 2019

Variant appearance in text: rs1045642
PMID: 31772608
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Gemtuzumab ozogamicin and novel antibody-drug conjugates in clinical trials for acute myeloid leukemia.

Biomarker Research
B Yu, D Liu
Publication Date: 2019

Variant appearance in text: N/A
PMID: 31695916
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Variation in Actionable Pharmacogenetic Markers in Natives and Mestizos From Mexico.

Frontiers In Pharmacology
V Gonzalez-Covarrubias, M Morales-Franco, OF Cruz-Correa, A Martínez-Hernández, H García-Ortíz, F Barajas-Olmos, AD Genis-Mendoza, JJ Martínez-Magaña, H Nicolini, L Orozco, X Soberón
Publication Date: 2019

Variant appearance in text: rs1045642
PMID: 31649539
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The Impact of CYP3A4*22 on Tacrolimus Pharmacokinetics and Outcome in Clinical Practice at a Single Kidney Transplant Center.

Frontiers In Genetics
E Abdel-Kahaar, S Winter, R Tremmel, E Schaeffeler, CJ Olbricht, E Wieland, M Schwab, M Shipkova, SU Jaeger
Publication Date: 2019

Variant appearance in text: rs1045642
PMID: 31616470
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Variability in expression of the human MDR1 drug efflux transporter and genetic variation of the ABCB1 gene: implications for drug-resistant epilepsy.

Current Opinion In Toxicology
A Heinrich, XB Zhong, TP Rasmussen
Publication Date: 2018

Variant appearance in text: N/A
PMID: 31602418
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Clinical and Genetic Factors Associated with Resistance to Treatment in Patients with Schizophrenia: A Case-Control Study.

International Journal Of Molecular Sciences
A Hajj, S Obeid, S Sahyoun, C Haddad, J Azar, L Rabbaa Khabbaz, S Hallit
Publication Date: 2019-09-25

Variant appearance in text: rs1045642
PMID: 31557839
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CYP2D6 Genotype Predicts Plasma Concentrations of Tamoxifen Metabolites in Ethiopian Breast Cancer Patients.

Cancers
JH Ahmed, E Makonnen, A Fotoohi, A Aseffa, R Howe, E Aklillu
Publication Date: 2019-09-12

Variant appearance in text: rs1045642
PMID: 31547390
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Association of CYP2C19 Polymorphism with Clopidogrel Resistance in Patients with Acute Coronary Syndrome in China.

Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research
Q Su, J Li, Z Tang, S Yang, G Xing, T Liu, H Peng
Publication Date: 2019-09-23

Variant appearance in text: rs1045642
PMID: 31543510
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Novel analytical methods to interpret large sequencing data from small sample sizes.

Human Genomics
F Lichou, S Orazio, S Dulucq, G Etienne, M Longy, C Hubert, A Groppi, A Monnereau, FX Mahon, B Turcq
Publication Date: 2019-08-30

Variant appearance in text: rs1045642
PMID: 31470908
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Unexpected excessive apixaban exposure: case report of a patient with polymorphisms of multiple apixaban elimination pathways.

Bmc Pharmacology & Toxicology
A Huppertz, C Grond-Ginsbach, C Dumschat, KI Foerster, J Burhenne, J Weiss, D Czock, JC Purrucker, T Rizos, WE Haefeli
Publication Date: 2019-08-29

Variant appearance in text: rs1045642
PMID: 31464657
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Influence of CYP3A5 and ABCB1 Polymorphism on Tacrolimus Drug Dosing in South Indian Renal Allograft Recipients.

Indian Journal Of Nephrology
ME Fernando, M Sellappan, ND Srinivasa Prasad, S Suren, K Thirumalvalavan
Publication Date: 2019

Variant appearance in text: N/A
PMID: 31423060
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Pharmacogenomic Biomarkers in Docetaxel Treatment of Prostate Cancer: From Discovery to Implementation.

Genes
R Varnai, LM Koskinen, LE Mäntylä, I Szabo, LM FitzGerald, C Sipeky
Publication Date: 2019-08-08

Variant appearance in text: ABCB1: Ile1145Ile; rs1045642
PMID: 31398933
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Genetic polymorphisms analysis of pharmacogenomic VIP variants in Bai ethnic group from China.

Molecular Genetics & Genomic Medicine
W Chen, H Ding, Y Cheng, Q Li, R Dai, X Yang, C Zhang
Publication Date: 2019-09

Variant appearance in text: rs1045642
PMID: 31361092
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Influence of (ATP)-Binding Cassette Transporter Subfamily B Member 1 (ABCB1) Gene Polymorphism on the Efficacy of Remifentanil.

Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research
W Wang, Q Zhou, C Yuan
Publication Date: 2019-07-15

Variant appearance in text: N/A
PMID: 31346154
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Population pharmacokinetics of cyclosporine in Chinese children receiving hematopoietic stem cell transplantation.

Acta Pharmacologica Sinica
TF Li, L Hu, XL Ma, L Huang, XM Liu, XX Luo, WY Feng, CF Wu
Publication Date: 2019-12

Variant appearance in text: rs1045642
PMID: 31341257
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ABCB1 Gene Is Associated With Clinical Response to SNRIs in a Local Chinese Han Population.

Frontiers In Pharmacology
XX Shan, Y Qiu, WW Xie, RR Wu, Y Yu, HS Wu, LH Li
Publication Date: 2019

Variant appearance in text: rs1045642
PMID: 31333472
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Impact of NR1I2, adenosine triphosphate-binding cassette transporters genetic polymorphisms on the pharmacokinetics of ginsenoside compound K in healthy Chinese volunteers.

Journal Of Ginseng Research
L Zhou, L Chen, Y Wang, J Huang, G Yang, Z Tan, Y Wang, J Liao, G Zhou, K Hu, Z Li, D Ouyang
Publication Date: 2019-07

Variant appearance in text: ABCB1: I1145I; rs1045642
PMID: 31308818
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Effect of patient genetics on etonogestrel pharmacokinetics when combined with efavirenz or nevirapine ART.

The Journal Of Antimicrobial Chemotherapy
M Neary, CA Chappell, KK Scarsi, S Nakalema, J Matovu, SL Achilles, BA Chen, M Siccardi, A Owen, M Lamorde
Publication Date: 2019-10-01

Variant appearance in text: rs1045642
PMID: 31299074
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Abstracts from the 51st European Society of Human Genetics Conference: Posters.

European Journal Of Human Genetics : Ejhg
.
Publication Date: 2019-07

Variant appearance in text: N/A
PMID: 31270413
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Analyzing and Reanalyzing the Genome: Findings from the MedSeq Project.

American Journal Of Human Genetics
K Machini, O Ceyhan-Birsoy, DR Azzariti, H Sharma, P Rossetti, L Mahanta, L Hutchinson, H McLaughlin, , RC Green, M Lebo, HL Rehm
Publication Date: 2019-07-03

Variant appearance in text: rs1045642
PMID: 31256874
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A meta-analysis of MDR1 polymorphisms rs1128503 and rs1045642 and susceptibility to hepatocellular carcinoma.

The Journal Of International Medical Research
Q Chang, ZL He, YC Peng, SG Duan, YX Dai, XH Zhao
Publication Date: 2019-07

Variant appearance in text: N/A
PMID: 31234681
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Colchicine Myopathy: A Case Series Including Muscle MRI and ABCB1 Polymorphism Data.

Frontiers In Neurology
M Gupta, A Nikolic, D Ng, K Martens, H Ebadi, S Chhibber, G Pfeffer
Publication Date: 2019

Variant appearance in text: rs1045642
PMID: 31178824
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Targeted ultra-deep sequencing of a South African Bantu-speaking cohort to comprehensively map and characterize common and novel variants in 65 pharmacologically-related genes.

Pharmacogenetics And Genomics
S Tshabalala, A Choudhury, N Beeton-Kempen, N Martinson, M Ramsay, D Mancama
Publication Date: 2019-09

Variant appearance in text: rs1045642
PMID: 31162291
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Targeted next generation sequencing as a tool for precision medicine.

Bmc Medical Genomics
M Gulilat, T Lamb, WA Teft, J Wang, JS Dron, JF Robinson, RG Tirona, RA Hegele, RB Kim, UI Schwarz
Publication Date: 2019-06-03

Variant appearance in text: ABCB1: I1145I; rs1045642
PMID: 31159795
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ABCB1 SNP predicts outcome in patients with acute myeloid leukemia treated with Gemtuzumab ozogamicin: a report from Children's Oncology Group AAML0531 Trial.

Blood Cancer Journal
R Rafiee, L Chauhan, TA Alonzo, YC Wang, A Elmasry, MR Loken, J Pollard, R Aplenc, S Raimondi, BA Hirsch, ID Bernstein, AS Gamis, S Meshinchi, JK Lamba
Publication Date: 2019-05-21

Variant appearance in text: ABCB1: Ile1145Ile; rs1045642
PMID: 31113932
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Implications of genetic variation of common Drug Metabolizing Enzymes and ABC Transporters among the Pakistani Population.

Scientific Reports
NA Afsar, H Bruckmueller, AN Werk, MK Nisar, HR Ahmad, I Cascorbi
Publication Date: 2019-05-13

Variant appearance in text: rs1045642
PMID: 31086207
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Genetic Variants Associated with Cancer Pain and Response to Opioid Analgesics: Implications for Precision Pain Management.

Seminars In Oncology Nursing
GS Yang, NM Barnes, DE Lyon, SG Dorsey
Publication Date: 2019-06

Variant appearance in text: rs1045642
PMID: 31085105
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Polymorphisms of ADME-related genes and their implications for drug safety and efficacy in Amazonian Amerindians.

Scientific Reports
JCG Rodrigues, MR Fernandes, JF Guerreiro, ALDC da Silva, Â Ribeiro-Dos-Santos, S Santos, NPCD Santos
Publication Date: 2019-05-10

Variant appearance in text: rs1045642
PMID: 31076604
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Evaluation of the impact of single-nucleotide polymorphisms on treatment response, survival and toxicity with cytarabine and anthracyclines in patients with acute myeloid leukaemia: a systematic review protocol.

Systematic Reviews
TC Puty, JS Sarraf, TC Do Carmo Almeida, VCB Filho, LEW de Carvalho, FLA Fonseca, F Adami
Publication Date: 2019-05-03

Variant appearance in text: N/A
PMID: 31053175
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Systems Approach to Identify Common Genes and Pathways Associated with Response to Selective Serotonin Reuptake Inhibitors and Major Depression Risk.

International Journal Of Molecular Sciences
A Srivastava, P Singh, H Gupta, H Kaur, N Kanojia, D Guin, M Sood, RK Chadda, J Yadav, D Vohora, L Saso, R Kukreti
Publication Date: 2019-04-23

Variant appearance in text: rs1045642
PMID: 31018568
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Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000265724.3 c.3435T>C p.Ile1145= synonymous_variant 27/29 -
ENST00000475929.1 n.591T>C - non_coding_transcript_exon_variant 4/5 -
ENST00000488737.2 n.1077T>C - non_coding_transcript_exon_variant 7/9 -
ENST00000543898.1 c.3243T>C p.Ile1081= synonymous_variant 24/26 -
NM_000927.4 c.3435T>C p.Ile1145= synonymous_variant 27/29 -
NM_001348944.1 c.3435T>C p.Ile1145= synonymous_variant 28/30 -
NM_001348945.1 c.3645T>C p.Ile1215= synonymous_variant 30/32 -
NM_001348946.2 c.3435T>C p.Ile1145= synonymous_variant 26/28 -