Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score.
Prostate Cancer And Prostatic Diseases
Huynh-Le, Minh-Phuong MP; Karunamuni, Roshan R; Fan, Chun Chieh CC; Asona, Lui L; Thompson, Wesley K WK; Martinez, Maria Elena ME; Eeles, Rosalind A RA; Kote-Jarai, Zsofia Z; Muir, Kenneth R KR; Lophatananon, Artitaya A; Schleutker, Johanna J; Pashayan, Nora N; Batra, Jyotsna J; Grönberg, Henrik H; Neal, David E DE; Nordestgaard, Børge G BG; Tangen, Catherine M CM; MacInnis, Robert J RJ; Wolk, Alicja A; Albanes, Demetrius D; Haiman, Christopher A CA; Travis, Ruth C RC; Blot, William J WJ; Stanford, Janet L JL; Mucci, Lorelei A LA; West, Catharine M L CML; Nielsen, Sune F SF; Kibel, Adam S AS; Cussenot, Olivier O; Berndt, Sonja I SI; Koutros, Stella S; Sørensen, Karina Dalsgaard KD; Cybulski, Cezary C; Grindedal, Eli Marie EM; Menegaux, Florence F; Park, Jong Y JY; Ingles, Sue A SA; Maier, Christiane C; Hamilton, Robert J RJ; Rosenstein, Barry S BS; Lu, Yong-Jie YJ; Watya, Stephen S; Vega, Ana A; Kogevinas, Manolis M; Wiklund, Fredrik F; Penney, Kathryn L KL; Huff, Chad D CD; Teixeira, Manuel R MR; Multigner, Luc L; Leach, Robin J RJ; Brenner, Hermann H; John, Esther M EM; Kaneva, Radka R; Logothetis, Christopher J CJ; Neuhausen, Susan L SL; De Ruyck, Kim K; Ost, Piet P; Razack, Azad A; Newcomb, Lisa F LF; Fowke, Jay H JH; Gamulin, Marija M; Abraham, Aswin A; Claessens, Frank F; Castelao, Jose Esteban JE; Townsend, Paul A PA; Crawford, Dana C DC; Petrovics, Gyorgy G; van Schaik, Ron H N RHN; Parent, Marie-Élise MÉ; Hu, Jennifer J JJ; Zheng, Wei W; , ; , ; , ; , ; , ; , ; , ; Mills, Ian G IG; Andreassen, Ole A OA; Dale, Anders M AM; Seibert, Tyler M TM
Polygenic hazard score is associated with prostate cancer in multi-ethnic populations.
Nature Communications
Huynh-Le, Minh-Phuong MP; Fan, Chun Chieh CC; Karunamuni, Roshan R; Thompson, Wesley K WK; Martinez, Maria Elena ME; Eeles, Rosalind A RA; Kote-Jarai, Zsofia Z; Muir, Kenneth K; Schleutker, Johanna J; Pashayan, Nora N; Batra, Jyotsna J; Grönberg, Henrik H; Neal, David E DE; Donovan, Jenny L JL; Hamdy, Freddie C FC; Martin, Richard M RM; Nielsen, Sune F SF; Nordestgaard, Børge G BG; Wiklund, Fredrik F; Tangen, Catherine M CM; Giles, Graham G GG; Wolk, Alicja A; Albanes, Demetrius D; Travis, Ruth C RC; Blot, William J WJ; Zheng, Wei W; Sanderson, Maureen M; Stanford, Janet L JL; Mucci, Lorelei A LA; West, Catharine M L CML; Kibel, Adam S AS; Cussenot, Olivier O; Berndt, Sonja I SI; Koutros, Stella S; Sørensen, Karina Dalsgaard KD; Cybulski, Cezary C; Grindedal, Eli Marie EM; Menegaux, Florence F; Khaw, Kay-Tee KT; Park, Jong Y JY; Ingles, Sue A SA; Maier, Christiane C; Hamilton, Robert J RJ; Thibodeau, Stephen N SN; Rosenstein, Barry S BS; Lu, Yong-Jie YJ; Watya, Stephen S; Vega, Ana A; Kogevinas, Manolis M; Penney, Kathryn L KL; Huff, Chad C; Teixeira, Manuel R MR; Multigner, Luc L; Leach, Robin J RJ; Cannon-Albright, Lisa L; Brenner, Hermann H; John, Esther M EM; Kaneva, Radka R; Logothetis, Christopher J CJ; Neuhausen, Susan L SL; De Ruyck, Kim K; Pandha, Hardev H; Razack, Azad A; Newcomb, Lisa F LF; Fowke, Jay H JH; Gamulin, Marija M; Usmani, Nawaid N; Claessens, Frank F; Gago-Dominguez, Manuela M; Townsend, Paul A PA; Bush, William S WS; Roobol, Monique J MJ; Parent, Marie-Élise MÉ; Hu, Jennifer J JJ; Mills, Ian G IG; Andreassen, Ole A OA; Dale, Anders M AM; Seibert, Tyler M TM; , ; , ; , ; , ; , ; , ; ,
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.
Nature Communications
Dadaev, Tokhir T; Saunders, Edward J EJ; Newcombe, Paul J PJ; Anokian, Ezequiel E; Leongamornlert, Daniel A DA; Brook, Mark N MN; Cieza-Borrella, Clara C; Mijuskovic, Martina M; Wakerell, Sarah S; Olama, Ali Amin Al AAA; Schumacher, Fredrick R FR; Berndt, Sonja I SI; Benlloch, Sara S; Ahmed, Mahbubl M; Goh, Chee C; Sheng, Xin X; Zhang, Zhuo Z; Muir, Kenneth K; Govindasami, Koveela K; Lophatananon, Artitaya A; Stevens, Victoria L VL; Gapstur, Susan M SM; Carter, Brian D BD; Tangen, Catherine M CM; Goodman, Phyllis P; Thompson, Ian M IM; Batra, Jyotsna J; Chambers, Suzanne S; Moya, Leire L; Clements, Judith J; Horvath, Lisa L; Tilley, Wayne W; Risbridger, Gail G; Gronberg, Henrik H; Aly, Markus M; Nordström, Tobias T; Pharoah, Paul P; Pashayan, Nora N; Schleutker, Johanna J; Tammela, Teuvo L J TLJ; Sipeky, Csilla C; Auvinen, Anssi A; Albanes, Demetrius D; Weinstein, Stephanie S; Wolk, Alicja A; Hakansson, Niclas N; West, Catharine C; Dunning, Alison M AM; Burnet, Neil N; Mucci, Lorelei L; Giovannucci, Edward E; Andriole, Gerald G; Cussenot, Olivier O; Cancel-Tassin, Géraldine G; Koutros, Stella S; Freeman, Laura E Beane LEB; Sorensen, Karina Dalsgaard KD; Orntoft, Torben Falck TF; Borre, Michael M; Maehle, Lovise L; Grindedal, Eli Marie EM; Neal, David E DE; Donovan, Jenny L JL; Hamdy, Freddie C FC; Martin, Richard M RM; Travis, Ruth C RC; Key, Tim J TJ; Hamilton, Robert J RJ; Fleshner, Neil E NE; Finelli, Antonio A; Ingles, Sue Ann SA; Stern, Mariana C MC; Rosenstein, Barry B; Kerns, Sarah S; Ostrer, Harry H; Lu, Yong-Jie YJ; Zhang, Hong-Wei HW; Feng, Ninghan N; Mao, Xueying X; Guo, Xin X; Wang, Guomin G; Sun, Zan Z; Giles, Graham G GG; Southey, Melissa C MC; MacInnis, Robert J RJ; FitzGerald, Liesel M LM; Kibel, Adam S AS; Drake, Bettina F BF; Vega, Ana A; Gómez-Caamaño, Antonio A; Fachal, Laura L; Szulkin, Robert R; Eklund, Martin M; Kogevinas, Manolis M; Llorca, Javier J; Castaño-Vinyals, Gemma G; Penney, Kathryn L KL; Stampfer, Meir M; Park, Jong Y JY; Sellers, Thomas A TA; Lin, Hui-Yi HY; Stanford, Janet L JL; Cybulski, Cezary C; Wokolorczyk, Dominika D; Lubinski, Jan J; Ostrander, Elaine A EA; Geybels, Milan S MS; Nordestgaard, Børge G BG; Nielsen, Sune F SF; Weisher, Maren M; Bisbjerg, Rasmus R; Røder, Martin Andreas MA; Iversen, Peter P; Brenner, Hermann H; Cuk, Katarina K; Holleczek, Bernd B; Maier, Christiane C; Luedeke, Manuel M; Schnoeller, Thomas T; Kim, Jeri J; Logothetis, Christopher J CJ; John, Esther M EM; Teixeira, Manuel R MR; Paulo, Paula P; Cardoso, Marta M; Neuhausen, Susan L SL; Steele, Linda L; Ding, Yuan Chun YC; De Ruyck, Kim K; De Meerleer, Gert G; Ost, Piet P; Razack, Azad A; Lim, Jasmine J; Teo, Soo-Hwang SH; Lin, Daniel W DW; Newcomb, Lisa F LF; Lessel, Davor D; Gamulin, Marija M; Kulis, Tomislav T; Kaneva, Radka R; Usmani, Nawaid N; Slavov, Chavdar C; Mitev, Vanio V; Parliament, Matthew M; Singhal, Sandeep S; Claessens, Frank F; Joniau, Steven S; Van den Broeck, Thomas T; Larkin, Samantha S; Townsend, Paul A PA; Aukim-Hastie, Claire C; Gago-Dominguez, Manuela M; Castelao, Jose Esteban JE; Martinez, Maria Elena ME; Roobol, Monique J MJ; Jenster, Guido G; van Schaik, Ron H N RHN; Menegaux, Florence F; Truong, Thérèse T; Koudou, Yves Akoli YA; Xu, Jianfeng J; Khaw, Kay-Tee KT; Cannon-Albright, Lisa L; Pandha, Hardev H; Michael, Agnieszka A; Kierzek, Andrzej A; Thibodeau, Stephen N SN; McDonnell, Shannon K SK; Schaid, Daniel J DJ; Lindstrom, Sara S; Turman, Constance C; Ma, Jing J; Hunter, David J DJ; Riboli, Elio E; Siddiq, Afshan A; Canzian, Federico F; Kolonel, Laurence N LN; Le Marchand, Loic L; Hoover, Robert N RN; Machiela, Mitchell J MJ; Kraft, Peter P; , ; Freedman, Matthew M; Wiklund, Fredrik F; Chanock, Stephen S; Henderson, Brian E BE; Easton, Douglas F DF; Haiman, Christopher A CA; Eeles, Rosalind A RA; Conti, David V DV; Kote-Jarai, Zsofia Z
Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts.
Bmj (Clinical Research Ed.)
Seibert, Tyler M TM; Fan, Chun Chieh CC; Wang, Yunpeng Y; Zuber, Verena V; Karunamuni, Roshan R; Parsons, J Kellogg JK; Eeles, Rosalind A RA; Easton, Douglas F DF; Kote-Jarai, ZSofia Z; Al Olama, Ali Amin AA; Garcia, Sara Benlloch SB; Muir, Kenneth K; Grönberg, Henrik H; Wiklund, Fredrik F; Aly, Markus M; Schleutker, Johanna J; Sipeky, Csilla C; Tammela, Teuvo Lj TL; Nordestgaard, Børge G BG; Nielsen, Sune F SF; Weischer, Maren M; Bisbjerg, Rasmus R; Røder, M Andreas MA; Iversen, Peter P; Key, Tim J TJ; Travis, Ruth C RC; Neal, David E DE; Donovan, Jenny L JL; Hamdy, Freddie C FC; Pharoah, Paul P; Pashayan, Nora N; Khaw, Kay-Tee KT; Maier, Christiane C; Vogel, Walther W; Luedeke, Manuel M; Herkommer, Kathleen K; Kibel, Adam S AS; Cybulski, Cezary C; Wokolorczyk, Dominika D; Kluzniak, Wojciech W; Cannon-Albright, Lisa L; Brenner, Hermann H; Cuk, Katarina K; Saum, Kai-Uwe KU; Park, Jong Y JY; Sellers, Thomas A TA; Slavov, Chavdar C; Kaneva, Radka R; Mitev, Vanio V; Batra, Jyotsna J; Clements, Judith A JA; Spurdle, Amanda A; Teixeira, Manuel R MR; Paulo, Paula P; Maia, Sofia S; Pandha, Hardev H; Michael, Agnieszka A; Kierzek, Andrzej A; Karow, David S DS; Mills, Ian G IG; Andreassen, Ole A OA; Dale, Anders M AM; ,
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.
Human Molecular Genetics
Amin Al Olama, Ali A; Dadaev, Tokhir T; Hazelett, Dennis J DJ; Li, Qiuyan Q; Leongamornlert, Daniel D; Saunders, Edward J EJ; Stephens, Sarah S; Cieza-Borrella, Clara C; Whitmore, Ian I; Benlloch Garcia, Sara S; Giles, Graham G GG; Southey, Melissa C MC; Fitzgerald, Liesel L; Gronberg, Henrik H; Wiklund, Fredrik F; Aly, Markus M; Henderson, Brian E BE; Schumacher, Fredrick F; Haiman, Christopher A CA; Schleutker, Johanna J; Wahlfors, Tiina T; Tammela, Teuvo L TL; Nordestgaard, Børge G BG; Key, Tim J TJ; Travis, Ruth C RC; Neal, David E DE; Donovan, Jenny L JL; Hamdy, Freddie C FC; Pharoah, Paul P; Pashayan, Nora N; Khaw, Kay-Tee KT; Stanford, Janet L JL; Thibodeau, Stephen N SN; Mcdonnell, Shannon K SK; Schaid, Daniel J DJ; Maier, Christiane C; Vogel, Walther W; Luedeke, Manuel M; Herkommer, Kathleen K; Kibel, Adam S AS; Cybulski, Cezary C; Wokołorczyk, Dominika D; Kluzniak, Wojciech W; Cannon-Albright, Lisa L; Brenner, Hermann H; Butterbach, Katja K; Arndt, Volker V; Park, Jong Y JY; Sellers, Thomas T; Lin, Hui-Yi HY; Slavov, Chavdar C; Kaneva, Radka R; Mitev, Vanio V; Batra, Jyotsna J; Clements, Judith A JA; Spurdle, Amanda A; Teixeira, Manuel R MR; Paulo, Paula P; Maia, Sofia S; Pandha, Hardev H; Michael, Agnieszka A; Kierzek, Andrzej A; Govindasami, Koveela K; Guy, Michelle M; Lophatonanon, Artitaya A; Muir, Kenneth K; Viñuela, Ana A; Brown, Andrew A AA; , ; , ; , ; , ; , ; Freedman, Mathew M; Conti, David V DV; Easton, Douglas D; Coetzee, Gerhard A GA; Eeles, Rosalind A RA; Kote-Jarai, Zsofia Z