Publications:

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Why We Need to Take a Closer Look at Genetic Contributions to CYP3A Activity.

Frontiers In Pharmacology

Zhai, Qinglian Q; van der Lee, Maaike M; van Gelder, Teun T; Swen, Jesse J JJ

Publication Date: 2022

Variant appearance in text: CYP3A4: P467S; rs4986913

PubMed Link: 35784699

Variant Present in the following documents:

• Main text
• fphar-13-912618.pdf

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Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Translational And Clinical Pharmacology

Kim, Byungwook B; Yoon, Deok Yong DY; Lee, SeungHwan S; Jang, In-Jin IJ; Yu, Kyung-Sang KS; Cho, Joo-Youn JY; Oh, Jaeseong J

Publication Date: 2021-09

Variant appearance in text: CYP3A4: P467S; rs4986913

PubMed Link: 34621706

Variant Present in the following documents:

• tcp-29-135-s001.xls, sheet 1

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Analysis of Comprehensive Pharmacogenomic Profiling of VIP Variants Among the Genetically Isolated Chechen Subpopulation from Jordan.

Pharmacogenomics And Personalized Medicine

Al-Eitan, Laith N LN; Rababa'h, Doaa M DM; Hakooz, Nancy M NM; Alghamdi, Mansour A MA; Dajani, Rana B RB

Publication Date: 2020

Variant appearance in text: rs4986913

PubMed Link: 32765042

Variant Present in the following documents:

• Main text
• pgpm-13-199.pdf

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Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing.

Clinical Pharmacokinetics

Yin, Anyue A; Ettaieb, Madeleine H T MHT; Swen, Jesse J JJ; van Deun, Liselotte L; Kerkhofs, Thomas M A TMA; van der Straaten, Robert J H M RJHM; Corssmit, Eleonora P M EPM; Gelderblom, Hans H; Kerstens, Michiel N MN; Feelders, Richard A RA; Eekhoff, Marelise M; Timmers, Henri J L M HJLM; D'Avolio, Antonio A; Cusato, Jessica J; Guchelaar, Henk-Jan HJ; Haak, Harm R HR; Moes, Dirk Jan A R DJAR

Publication Date: 2021-01

Variant appearance in text: CYP3A4: P467S; rs4986913

PubMed Link: 32607875

Variant Present in the following documents:

• 40262_2020_913_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Genetic Polymorphisms of Pharmacogenes among the Genetically Isolated Circassian Subpopulation from Jordan.

Journal Of Personalized Medicine

Al-Eitan, Laith N LN; Rababa'h, Doaa M DM; Hakooz, Nancy M NM; Alghamdi, Mansour A MA; Dajani, Rana B RB

Publication Date: 2020-01-06

Variant appearance in text: rs4986913

PubMed Link: 31935801

Variant Present in the following documents:

• Main text
• jpm-10-00002.pdf

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Enzymatic Activities of CYP3A4 Allelic Variants on Quinine 3-Hydroxylation In Vitro.

Frontiers In Pharmacology

Zhou, Xiao-Yang XY; Hu, Xiao-Xia XX; Wang, Chen-Chen CC; Lu, Xiang-Ran XR; Chen, Zhe Z; Liu, Qian Q; Hu, Guo-Xin GX; Cai, Jian-Ping JP

Publication Date: 2019

Variant appearance in text: CYP3A4: P467S

PubMed Link: 31214030

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic analysis of pharmacogenomic VIP variants in the Blang population from Yunnan Province of China.

Molecular Genetics & Genomic Medicine

Zhang, Chan C; Guo, Weiwei W; Cheng, Yujing Y; Li, Qi Q; Yang, Xin X; Dai, Run R; Zhu, Linhao L; Chen, Wanlu W

Publication Date: 2019-05

Variant appearance in text: rs4986913

PubMed Link: 30955239

Variant Present in the following documents:

• Main text
• MGG3-7-e574.pdf

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Polymorphism in Cytochrome P450 3A4 Is Ethnicity Related.

Frontiers In Genetics

Guttman, Yelena Y; Nudel, Adi A; Kerem, Zohar Z

Publication Date: 2019

Variant appearance in text: rs4986913

PubMed Link: 30941162

Variant Present in the following documents:

• Table_2.xlsx, sheet 8
• Table_2.xlsx, sheet 3

View BVdb publication page

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An optimized prediction framework to assess the functional impact of pharmacogenetic variants.

The Pharmacogenomics Journal

Zhou, Yitian Y; Mkrtchian, Souren S; Kumondai, Masaki M; Hiratsuka, Masahiro M; Lauschke, Volker M VM

Publication Date: 2019-04

Variant appearance in text: CYP3A4: P467S; rs4986913

PubMed Link: 30206299

Variant Present in the following documents:

• 41397_2018_44_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Biological Predictors of Clozapine Response: A Systematic Review.

Frontiers In Psychiatry

Samanaite, Ruta R; Gillespie, Amy A; Sendt, Kyra-Verena KV; McQueen, Grant G; MacCabe, James H JH; Egerton, Alice A

Publication Date: 2018

Variant appearance in text: rs4986913

PubMed Link: 30093869

Variant Present in the following documents:

• fpsyt-09-00327.pdf

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Genetic polymorphisms in very important pharmacogenomic variants in the Zhuang ethnic group of Southwestern China: A cohort study in the Zhuang population.

Medicine

Li, Jing J; Guo, Chenghao C; Yan, Mengdan M; Niu, Fanglin F; Chen, Peng P; Li, Bin B; Jin, Tianbo T

Publication Date: 2018-04

Variant appearance in text: rs4986913

PubMed Link: 29703042

Variant Present in the following documents:

• medi-97-e0559.pdf

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Functional assessment of CYP3A4 allelic variants on lidocaine metabolism in vitro.

Drug Design, Development And Therapy

Fang, Ping P; Tang, Peng-Fei PF; Xu, Ren-Ai RA; Zheng, Xiang X; Wen, Jian J; Bao, Su-Su SS; Cai, Jian-Ping JP; Hu, Guo-Xin GX

Publication Date: 2017

Variant appearance in text: CYP3A4: P467S

PubMed Link: 29263648

Variant Present in the following documents:

• Main text
• dddt-11-3503.pdf

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Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Clinical Pharmacology And Therapeutics

Zhou, Y Y; Ingelman-Sundberg, M M; Lauschke, V M VM

Publication Date: 2017-10

Variant appearance in text: CYP3A4: P467S; rs4986913

PubMed Link: 28378927

Variant Present in the following documents:

• Main text
• CPT-102-688.pdf

View BVdb publication page

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Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics

Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR

Publication Date: 2017-03

Variant appearance in text: CYP3A4: P467S; rs4986913

PubMed Link: 27984508

Variant Present in the following documents:

• fpc-27-089-s005.xlsx, sheet 2

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Rapid and ultra-rapid metabolizers with CYP2C19*17 polymorphism do not respond to standard therapy with proton pump inhibitors.

Meta Gene

Deshpande, Neha N; V, Sharanya S; V V, Ravi Kanth RK; H V V, Murthy M; M, Sasikala S; Banerjee, Rupa R; Tandan, Manu M; D, Nageshwar Reddy NR

Publication Date: 2016-09

Variant appearance in text: CYP3A4: P467S; rs4986913

PubMed Link: 27419077

Variant Present in the following documents:

• Main text

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Genetic polymorphisms of pharmacogenomic VIP variants in the Mongol of Northwestern China.

Bmc Genetics

Jin, Tianbo T; Shi, Xugang X; Wang, Li L; Wang, Huijuan H; Feng, Tian T; Kang, Longli L

Publication Date: 2016-05-28

Variant appearance in text: rs4986913

PubMed Link: 27233804

Variant Present in the following documents:

• Main text
• 12863_2016_Article_379.pdf

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Genetic polymorphisms of pharmacogenomic VIP variants in the lhoba population of southwest China.

International Journal Of Clinical And Experimental Pathology

He, Yongjun Y; Yang, Hua H; Geng, Tingting T; Feng, Tian T; Yuan, Dongya D; Kang, Longli L; Luo, Manling M; Jin, Tianbo T

Publication Date: 2015

Variant appearance in text: rs4986913

PubMed Link: 26722533

Variant Present in the following documents:

• Main text

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Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One

Holehouse, Alex S AS; Naegle, Kristen M KM

Publication Date: 2015

Variant appearance in text: rs4986913

PubMed Link: 26659599

Variant Present in the following documents:

• pone.0144692.s002.xlsx, sheet 1

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Genetic polymorphisms of pharmacogenomic VIP variants in the Uygur population from northwestern China.

Bmc Genetics

Wang, Li L; Aikemu, Ainiwaer A; Yibulayin, Ayiguli A; Du, Shuli S; Geng, Tingting T; Wang, Bo B; Zhang, Yuan Y; Jin, Tianbo T; Yang, Jie J

Publication Date: 2015-06-20

Variant appearance in text: CYP3A4: Pro467Ser; rs4986913

PubMed Link: 26091847

Variant Present in the following documents:

• Main text
• 12863_2015_Article_232.pdf

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The Affymetrix DMET Plus platform reveals unique distribution of ADME-related variants in ethnic Arabs.

Disease Markers

Wakil, Salma M SM; Nguyen, Cao C; Muiya, Nzioka P NP; Andres, Editha E; Lykowska-Tarnowska, Agnieszka A; Baz, Batoul B; Tahir, Asma I AI; Meyer, Brian F BF; Morahan, Grant G; Dzimiri, Nduna N

Publication Date: 2015

Variant appearance in text: rs4986913

PubMed Link: 25802476

Variant Present in the following documents:

• 542543.f1.xlsx, sheet 1

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Genetic polymorphisms of VIP variants in the Tajik ethnic group of northwest China.

Bmc Genetics

Zhang, Jiayi J; Jin, Tianbo T; Yunus, Zulfiya Z; Li, Xiaolan X; Geng, Tingting T; Wang, Hong H; Cui, Yali Y; Chen, Chao C

Publication Date: 2014-09-30

Variant appearance in text: rs4986913

PubMed Link: 25266489

Variant Present in the following documents:

• Main text
• 12863_2014_Article_102.pdf

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The RPTEC/TERT1 cell line models key renal cell responses to the environmental toxicants, benzo[a]pyrene and cadmium.

Toxicology Reports

Simon, B R BR; Wilson, M J MJ; Wickliffe, J K JK

Publication Date: 2014

Variant appearance in text: rs4986913

PubMed Link: 25126521

Variant Present in the following documents:

• mmc1.xls, sheet 1

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The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy.

Journal Of Personalized Medicine

Wang, Danxin D; Sadee, Wolfgang W

Publication Date: 2012-10-29

Variant appearance in text: CYP3A4: P467S; rs4986913

PubMed Link: 24466438

Variant Present in the following documents:

• Main text

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Screening of Genetic Polymorphisms of CYP3A4 and CYP3A5 Genes.

The Korean Journal Of Physiology & Pharmacology : Official Journal Of The Korean Physiological Society And The Korean Society Of Pharmacology

Lee, Jin Sol JS; Cheong, Hyun Sub HS; Kim, Lyoung Hyo LH; Kim, Ji On JO; Seo, Doo Won DW; Kim, Young Hoon YH; Chung, Myeon Woo MW; Han, Soon Young SY; Shin, Hyoung Doo HD

Publication Date: 2013-12

Variant appearance in text: CYP3A4: P467S; rs4986913

PubMed Link: 24381495

Variant Present in the following documents:

• kjpp-17-479.pdf

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Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem.

Frontiers In Genetics

Klein, Kathrin K; Zanger, Ulrich M UM

Publication Date: 2013

Variant appearance in text: rs4986913

PubMed Link: 23444277

Variant Present in the following documents:

• Main text
• fgene-04-00012.pdf

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Population analysis of pharmacogenetic polymorphisms related to acute lymphoblastic leukemia drug treatment.

Disease Markers

Chiabai, Marcela A MA; Lins, Tulio C L TC; Pogue, Robert R; Pereira, Rinaldo W RW

Publication Date: 2012

Variant appearance in text: rs4986913

PubMed Link: 22430191

Variant Present in the following documents:

• DM32-04-928940.pdf

View BVdb publication page

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Genotyping panel for assessing response to cancer chemotherapy.

Bmc Medical Genomics

Dai, Zunyan Z; Papp, Audrey C AC; Wang, Danxin D; Hampel, Heather H; Sadee, Wolfgang W

Publication Date: 2008-06-11

Variant appearance in text: rs4986913

PubMed Link: 18547414

Variant Present in the following documents:

• 1755-8794-1-24-S1.xls, sheet 1

View BVdb publication page

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Reduced methylprednisolone clearance causing prolonged pharmacodynamics in a healthy subject was not associated with CYP3A5*3 allele or a change in diet composition.

Journal Of Clinical Pharmacology

Lee, Su-Jun SJ; Jusko, William J WJ; Salaita, Christine G CG; Calis, Karim A KA; Jann, Michael W MW; Spratlin, Vicky E VE; Goldstein, Joyce A JA; Hon, Yuen Yi YY

Publication Date: 2006-05

Variant appearance in text: CYP3A4: Pro467Ser

PubMed Link: 16638735

Variant Present in the following documents:

• Main text

View BVdb publication page

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