CYP3A4 c.1247C>G ;(p.P416R)

Variant ID: 7-99359670-G-C

NM_017460.5(CYP3A4):c.1247C>G;(p.P416R)

This variant was identified in 19 publications

View GRCh38 version.




Publications:


Genetic variants related to successful migraine prophylaxis with verapamil.

Molecular Genetics & Genomic Medicine
Cutrer, Fred Michael FM; Moyer, Ann M AM; Atkinson, Elizabeth J EJ; Wang, Liguo L; Tian, Shulan S; Wu, Yanhong Y; Garza, Ivan I; Robertson, Carrie E CE; Huebert, Carey A CA; Moore, Brenda E BE; Klein, Christopher J CJ
Publication Date: 2021-06

Variant appearance in text: rs4986909
PubMed Link: 33829662
Variant Present in the following documents:
  • Main text
  • MGG3-9-e1680.pdf
View BVdb publication page



Genetic variants related to successful migraine prophylaxis with verapamil.

Molecular Genetics & Genomic Medicine
Cutrer, Fred Michael FM; Moyer, Ann M AM; Atkinson, Elizabeth J EJ; Wang, Liguo L; Tian, Shulan S; Wu, Yanhong Y; Garza, Ivan I; Robertson, Carrie E CE; Huebert, Carey A CA; Moore, Brenda E BE; Klein, Christopher J CJ
Publication Date: 2021-06

Variant appearance in text: rs4986909
PubMed Link: 33829662
Variant Present in the following documents:
  • Main text
  • MGG3-9-e1680.pdf
View BVdb publication page



Analysis of Comprehensive Pharmacogenomic Profiling of VIP Variants Among the Genetically Isolated Chechen Subpopulation from Jordan.

Pharmacogenomics And Personalized Medicine
Al-Eitan, Laith N LN; Rababa'h, Doaa M DM; Hakooz, Nancy M NM; Alghamdi, Mansour A MA; Dajani, Rana B RB
Publication Date: 2020

Variant appearance in text: rs4986909
PubMed Link: 32765042
Variant Present in the following documents:
  • Main text
  • pgpm-13-199.pdf
View BVdb publication page



Pharmacogenomics of methadone: a narrative review of the literature.

Pharmacogenomics
Packiasabapathy, Senthil S; Aruldhas, Blessed W BW; Horn, Nicole N; Overholser, Brian R BR; Quinney, Sara K SK; Renschler, Janelle S JS; Sadhasivam, Senthilkumar S
Publication Date: 2020-08

Variant appearance in text: rs4986909
PubMed Link: 32705966
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic Polymorphisms of Pharmacogenes among the Genetically Isolated Circassian Subpopulation from Jordan.

Journal Of Personalized Medicine
Al-Eitan, Laith N LN; Rababa'h, Doaa M DM; Hakooz, Nancy M NM; Alghamdi, Mansour A MA; Dajani, Rana B RB
Publication Date: 2020-01-06

Variant appearance in text: rs4986909
PubMed Link: 31935801
Variant Present in the following documents:
  • Main text
  • jpm-10-00002.pdf
View BVdb publication page



Genetic analysis of pharmacogenomic VIP variants in the Blang population from Yunnan Province of China.

Molecular Genetics & Genomic Medicine
Zhang, Chan C; Guo, Weiwei W; Cheng, Yujing Y; Li, Qi Q; Yang, Xin X; Dai, Run R; Zhu, Linhao L; Chen, Wanlu W
Publication Date: 2019-05

Variant appearance in text: rs4986909
PubMed Link: 30955239
Variant Present in the following documents:
  • Main text
  • MGG3-7-e574.pdf
View BVdb publication page



Polymorphism in Cytochrome P450 3A4 Is Ethnicity Related.

Frontiers In Genetics
Guttman, Yelena Y; Nudel, Adi A; Kerem, Zohar Z
Publication Date: 2019

Variant appearance in text: rs4986909
PubMed Link: 30941162
Variant Present in the following documents:
  • Table_2.xlsx, sheet 8
  • Table_2.xlsx, sheet 3
  • Table_2.xlsx, sheet 2
  • Table_2.xlsx, sheet 7
View BVdb publication page



Influence of Genetic Variants on Steady-State Etonogestrel Concentrations Among Contraceptive Implant Users.

Obstetrics And Gynecology
Lazorwitz, Aaron A; Aquilante, Christina L CL; Oreschak, Kris K; Sheeder, Jeanelle J; Guiahi, Maryam M; Teal, Stephanie S
Publication Date: 2019-04

Variant appearance in text: rs4986909
PubMed Link: 30870275
Variant Present in the following documents:
  • Main text
View BVdb publication page



Biological Predictors of Clozapine Response: A Systematic Review.

Frontiers In Psychiatry
Samanaite, Ruta R; Gillespie, Amy A; Sendt, Kyra-Verena KV; McQueen, Grant G; MacCabe, James H JH; Egerton, Alice A
Publication Date: 2018

Variant appearance in text: rs4986909
PubMed Link: 30093869
Variant Present in the following documents:
  • fpsyt-09-00327.pdf
View BVdb publication page



Genetic polymorphisms in very important pharmacogenomic variants in the Zhuang ethnic group of Southwestern China: A cohort study in the Zhuang population.

Medicine
Li, Jing J; Guo, Chenghao C; Yan, Mengdan M; Niu, Fanglin F; Chen, Peng P; Li, Bin B; Jin, Tianbo T
Publication Date: 2018-04

Variant appearance in text: rs4986909
PubMed Link: 29703042
Variant Present in the following documents:
  • medi-97-e0559.pdf
View BVdb publication page



Genetic variation in human drug-related genes.

Genome Medicine
Schärfe, Charlotta Pauline Irmgard CPI; Tremmel, Roman R; Schwab, Matthias M; Kohlbacher, Oliver O; Marks, Debora Susan DS
Publication Date: 2017-12-22

Variant appearance in text: rs4986909
PubMed Link: 29273096
Variant Present in the following documents:
  • 13073_2017_502_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Genetic polymorphisms of pharmacogenomic VIP variants in the Mongol of Northwestern China.

Bmc Genetics
Jin, Tianbo T; Shi, Xugang X; Wang, Li L; Wang, Huijuan H; Feng, Tian T; Kang, Longli L
Publication Date: 2016-05-28

Variant appearance in text: rs4986909
PubMed Link: 27233804
Variant Present in the following documents:
  • Main text
View BVdb publication page



Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One
Holehouse, Alex S AS; Naegle, Kristen M KM
Publication Date: 2015

Variant appearance in text: rs4986909
PubMed Link: 26659599
Variant Present in the following documents:
  • pone.0144692.s002.xlsx, sheet 1
View BVdb publication page



Genetic polymorphisms of pharmacogenomic VIP variants in the Uygur population from northwestern China.

Bmc Genetics
Wang, Li L; Aikemu, Ainiwaer A; Yibulayin, Ayiguli A; Du, Shuli S; Geng, Tingting T; Wang, Bo B; Zhang, Yuan Y; Jin, Tianbo T; Yang, Jie J
Publication Date: 2015-06-20

Variant appearance in text: rs4986909
PubMed Link: 26091847
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Affymetrix DMET Plus platform reveals unique distribution of ADME-related variants in ethnic Arabs.

Disease Markers
Wakil, Salma M SM; Nguyen, Cao C; Muiya, Nzioka P NP; Andres, Editha E; Lykowska-Tarnowska, Agnieszka A; Baz, Batoul B; Tahir, Asma I AI; Meyer, Brian F BF; Morahan, Grant G; Dzimiri, Nduna N
Publication Date: 2015

Variant appearance in text: rs4986909
PubMed Link: 25802476
Variant Present in the following documents:
  • 542543.f1.xlsx, sheet 1
View BVdb publication page



Genetic polymorphisms of VIP variants in the Tajik ethnic group of northwest China.

Bmc Genetics
Zhang, Jiayi J; Jin, Tianbo T; Yunus, Zulfiya Z; Li, Xiaolan X; Geng, Tingting T; Wang, Hong H; Cui, Yali Y; Chen, Chao C
Publication Date: 2014-09-30

Variant appearance in text: rs4986909
PubMed Link: 25266489
Variant Present in the following documents:
  • Main text
  • 12863_2014_Article_102.pdf
View BVdb publication page



The RPTEC/TERT1 cell line models key renal cell responses to the environmental toxicants, benzo[a]pyrene and cadmium.

Toxicology Reports
Simon, B R BR; Wilson, M J MJ; Wickliffe, J K JK
Publication Date: 2014

Variant appearance in text: rs4986909
PubMed Link: 25126521
Variant Present in the following documents:
  • mmc1.xls, sheet 1
View BVdb publication page



Pharmacogenetics in American Indian populations: analysis of CYP2D6, CYP3A4, CYP3A5, and CYP2C9 in the Confederated Salish and Kootenai Tribes.

Pharmacogenetics And Genomics
Fohner, Alison A; Muzquiz, LeeAnna I LI; Austin, Melissa A MA; Gaedigk, Andrea A; Gordon, Adam A; Thornton, Timothy T; Rieder, Mark J MJ; Pershouse, Mark A MA; Putnam, Elizabeth A EA; Howlett, Kevin K; Beatty, Patrick P; Thummel, Kenneth E KE; Woodahl, Erica L EL
Publication Date: 2013-08

Variant appearance in text: rs4986909
PubMed Link: 23778323
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem.

Frontiers In Genetics
Klein, Kathrin K; Zanger, Ulrich M UM
Publication Date: 2013

Variant appearance in text: rs4986909
PubMed Link: 23444277
Variant Present in the following documents:
  • Main text
  • fgene-04-00012.pdf
View BVdb publication page



Genotyping panel for assessing response to cancer chemotherapy.

Bmc Medical Genomics
Dai, Zunyan Z; Papp, Audrey C AC; Wang, Danxin D; Hampel, Heather H; Sadee, Wolfgang W
Publication Date: 2008-06-11

Variant appearance in text: rs4986909
PubMed Link: 18547414
Variant Present in the following documents:
  • 1755-8794-1-24-S1.xls, sheet 1
View BVdb publication page