CYP3A4 c.600A>T ;(p.Q200H)

Variant ID: 7-99366047-T-A

NM_017460.5(CYP3A4):c.600A>T;(p.Q200H)

This variant was identified in 9 publications

View GRCh38 version.




Publications:


Why We Need to Take a Closer Look at Genetic Contributions to CYP3A Activity.

Frontiers In Pharmacology
Zhai, Qinglian Q; van der Lee, Maaike M; van Gelder, Teun T; Swen, Jesse J JJ
Publication Date: 2022

Variant appearance in text: CYP3A4: Q200H; rs113667357
PubMed Link: 35784699
Variant Present in the following documents:
  • Main text
  • fphar-13-912618.pdf
View BVdb publication page



Pharmacogenetics of Breast Cancer Treatments: A Sub-Saharan Africa Perspective.

Pharmacogenomics And Personalized Medicine
Nthontho, Keneuoe Cecilia KC; Ndlovu, Andrew Khulekani AK; Sharma, Kirthana K; Kasvosve, Ishmael I; Hertz, Daniel Louis DL; Paganotti, Giacomo Maria GM
Publication Date: 2022

Variant appearance in text: CYP3A4: Q200H; rs113667357
PubMed Link: 35761855
Variant Present in the following documents:
  • Main text
  • pgpm-15-613.pdf
View BVdb publication page



Functional Measurement of CYP2C9 and CYP3A4 Allelic Polymorphism on Sildenafil Metabolism.

Drug Design, Development And Therapy
Tang, Peng-Fei PF; Zheng, Xiang X; Hu, Xiao-Xia XX; Yang, Cheng-Cheng CC; Chen, Zhe Z; Qian, Jian-Chang JC; Cai, Jian-Ping JP; Hu, Guo-Xin GX
Publication Date: 2020

Variant appearance in text: CYP3A4: Q200H
PubMed Link: 33262574
Variant Present in the following documents:
  • Main text
  • dddt-14-5129.pdf
View BVdb publication page



Enzymatic Activities of CYP3A4 Allelic Variants on Quinine 3-Hydroxylation In Vitro.

Frontiers In Pharmacology
Zhou, Xiao-Yang XY; Hu, Xiao-Xia XX; Wang, Chen-Chen CC; Lu, Xiang-Ran XR; Chen, Zhe Z; Liu, Qian Q; Hu, Guo-Xin GX; Cai, Jian-Ping JP
Publication Date: 2019

Variant appearance in text: CYP3A4: Q200H
PubMed Link: 31214030
Variant Present in the following documents:
  • Main text
  • fphar-10-00591.pdf
View BVdb publication page



Polymorphism in Cytochrome P450 3A4 Is Ethnicity Related.

Frontiers In Genetics
Guttman, Yelena Y; Nudel, Adi A; Kerem, Zohar Z
Publication Date: 2019

Variant appearance in text: rs113667357
PubMed Link: 30941162
Variant Present in the following documents:
  • Table_2.xlsx, sheet 2
  • Table_2.xlsx, sheet 7
View BVdb publication page



Functional assessment of CYP3A4 allelic variants on lidocaine metabolism in vitro.

Drug Design, Development And Therapy
Fang, Ping P; Tang, Peng-Fei PF; Xu, Ren-Ai RA; Zheng, Xiang X; Wen, Jian J; Bao, Su-Su SS; Cai, Jian-Ping JP; Hu, Guo-Xin GX
Publication Date: 2017

Variant appearance in text: CYP3A4: Q200H
PubMed Link: 29263648
Variant Present in the following documents:
  • Main text
  • dddt-11-3503.pdf
View BVdb publication page



Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics
Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR
Publication Date: 2017-03

Variant appearance in text: rs113667357
PubMed Link: 27984508
Variant Present in the following documents:
  • fpc-27-089-s005.xlsx, sheet 2
View BVdb publication page



Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem.

Frontiers In Genetics
Klein, Kathrin K; Zanger, Ulrich M UM
Publication Date: 2013

Variant appearance in text: rs113667357
PubMed Link: 23444277
Variant Present in the following documents:
  • Main text
  • fgene-04-00012.pdf
View BVdb publication page



Characterization of the genetic variation present in CYP3A4 in three South African populations.

Frontiers In Genetics
Drögemöller, Britt B; Plummer, Marieth M; Korkie, Lundi L; Agenbag, Gloudi G; Dunaiski, Anke A; Niehaus, Dana D; Koen, Liezl L; Gebhardt, Stefan S; Schneider, Nicol N; Olckers, Antonel A; Wright, Galen G; Warnich, Louise L
Publication Date: 2013

Variant appearance in text: CYP3A4: Q200H; rs113667357
PubMed Link: 23423246
Variant Present in the following documents:
  • Main text
  • fgene-04-00017.pdf
View BVdb publication page