Genetic variations that influence paclitaxel pharmacokinetics and intracellular effects that may contribute to chemotherapy-induced neuropathy: A narrative review.
Frontiers In Pain Research (Lausanne, Switzerland)
Johnson, Ken B KB; Sharma, Anukriti A; Henry, N Lynn NL; Wei, Mei M; Bie, Bihua B; Hershberger, Courtney E CE; Rhoades, Emily E EE; Sen, Alper A; Johnson, Ryan E RE; Steenblik, Jacob J; Hockings, Jennifer J; Budd, G Thomas GT; Eng, Charis C; Foss, Joseph J; Rotroff, Daniel M DM
Influence of germline variations in drug transporters ABCB1 and ABCG2 on intracerebral osimertinib efficacy in patients with non-small cell lung cancer.
Eclinicalmedicine
Veerman, G D Marijn GDM; Boosman, Rene J RJ; Jebbink, Merel M; Oomen-de Hoop, Esther E; van der Wekken, Anthonie J AJ; Bahce, Idris I; Hendriks, Lizza E L LEL; Croes, Sander S; Steendam, Christi M J CMJ; de Jonge, Evert E; Koolen, Stijn L W SLW; Steeghs, Neeltje N; van Schaik, Ron H N RHN; Smit, Egbert F EF; Dingemans, Anne-Marie C AC; Huitema, Alwin D R ADR; Mathijssen, Ron H J RHJ
Effects of CYP3A4*22 and CYP3A5 on clinical outcome in patients treated with ticagrelor for ST-segment elevation myocardial infarction: POPular Genetics sub-study.
Frontiers In Pharmacology
Azzahhafi, Jaouad J; Bergmeijer, Thomas O TO; van den Broek, Wout W A WWA; Chan Pin Yin, Dean R P P DRPP; Rayhi, Senna S; Peper, Joyce J; Bor, Willem L WL; Claassens, Daniel M F DMF; van Schaik, Ron H N RHN; Ten Berg, Jurriën M JM
Eight pharmacokinetic genetic variants are not associated with the risk of bleeding from direct oral anticoagulants in non-valvular atrial fibrillation patients.
Frontiers In Pharmacology
Campos-Staffico, Alessandra M AM; Dorsch, Michael P MP; Barnes, Geoffrey D GD; Zhu, Hao-Jie HJ; Limdi, Nita A NA; Luzum, Jasmine A JA
Genome-wide microRNA profiles identify miR-107 as a top miRNA associating with expression of the CYP3As and other drug metabolizing cytochrome P450 enzymes in the liver.
Frontiers In Pharmacology
Tantawy, Marwa M; Collins, Joseph M JM; Wang, Danxin D
Organic Anion Transporter Gene Variants Associated With Plasma Exposure and Long-Term Response to Atrasentan in Patients With Diabetic Kidney Disease.
Clinical Pharmacology And Therapeutics
Smeijer, J David JD; Koomen, Jeroen V JV; Kohan, Donald E DE; McMurray, John J V JJV; Bakris, George L GL; Correa-Rotter, Ricardo R; Hou, Fan-Fan FF; Kitzman, Dalane W DW; Makino, Hirofumi H; Mayer, Gert G; Nowicki, Michal M; Perkovic, Vlado V; Rossing, Peter P; Tobe, Sheldon S; Parving, Hans-Henrik HH; de Zeeuw, Dick D; Heerspink, Hiddo J L HJL
Pharmacogenetics of taxane-induced neurotoxicity in breast cancer: Systematic review and meta-analysis.
Clinical And Translational Science
Guijosa, Alberto A; Freyria, Ana A; Espinosa-Fernandez, Jose Rodrigo JR; Estrada-Mena, Francisco J FJ; Armenta-Quiroga, Ana Sofía AS; Ortega-Treviño, Maria Fernanda MF; Catalán, Rodrigo R; Antonio-Aguirre, Bani B; Villarreal-Garza, Cynthia C; Perez-Ortiz, Andric C AC
Pharmacogenetic Analysis of Voriconazole Treatment in Children.
Pharmaceutics
Tilen, Romy R; Paioni, Paolo P; Goetschi, Aljoscha N AN; Goers, Roland R; Seibert, Isabell I; Müller, Daniel D; Bielicki, Julia A JA; Berger, Christoph C; Krämer, Stefanie D SD; Meyer Zu Schwabedissen, Henriette E HE
Genomewide Association Study of Simvastatin Pharmacokinetics.
Clinical Pharmacology And Therapeutics
Mykkänen, Anssi J H AJH; Taskinen, Suvi S; Neuvonen, Mikko M; Paile-Hyvärinen, Maria M; Tarkiainen, E Katriina EK; Lilius, Tuomas T; Tapaninen, Tuija T; Backman, Janne T JT; Tornio, Aleksi A; Niemi, Mikko M
Single-nucleotide polymorphisms and the effectiveness of taxane-based chemotherapy in premenopausal breast cancer: a population-based cohort study in Denmark.
Breast Cancer Research And Treatment
Hjorth, Cathrine F CF; Damkier, Per P; Stage, Tore B TB; Feddersen, Søren S; Hamilton-Dutoit, Stephen S; Rørth, Mikael M; Ejlertsen, Bent B; Lash, Timothy L TL; Ahern, Thomas P TP; Sørensen, Henrik T HT; Cronin-Fenton, Deirdre D
Candidate genetic variants and antidepressant-related fall risk in middle-aged and older adults.
Plos One
Pronk, A C AC; Seppala, L J LJ; Trajanoska, K K; Stringa, N N; van de Loo, B B; de Groot, L C P G M LCPGM; van Schoor, N M NM; Koskeridis, F F; Markozannes, G G; Ntzani, E E; Uitterlinden, A G AG; Rivadeneira, F F; Stricker, B H BH; van der Velde, N N
Development of the ADFICE_IT Models for Predicting Falls and Recurrent Falls in Community-Dwelling Older Adults: Pooled Analyses of European Cohorts With Special Attention to Medication.
The Journals Of Gerontology. Series A, Biological Sciences And Medical Sciences
van de Loo, Bob B; Seppala, Lotta J LJ; van der Velde, Nathalie N; Medlock, Stephanie S; Denkinger, Michael M; de Groot, Lisette Cpgm LC; Kenny, Rose-Anne RA; Moriarty, Frank F; Rothenbacher, Dietrich D; Stricker, Bruno B; Uitterlinden, André A; Abu-Hanna, Ameen A; Heymans, Martijn W MW; van Schoor, Natasja N
Role of Pharmacogenetics in the Treatment of Acute Myeloid Leukemia: Systematic Review and Future Perspectives.
Pharmaceutics
Pinto-Merino, Álvaro Á; Labrador, Jorge J; Zubiaur, Pablo P; Alcaraz, Raquel R; Herrero, María José MJ; Montesinos, Pau P; Abad-Santos, Francisco F; Saiz-Rodríguez, Miriam M
Warfarin Pharmacogenomics for Precision Medicine in Real-Life Clinical Practice in Southern Africa: Harnessing 73 Variants in 29 Pharmacogenes.
Omics : A Journal Of Integrative Biology
Muyambo, Sarudzai S; Ndadza, Arinao A; Soko, Nyarai D ND; Kruger, Bianca B; Kadzirange, Gerard G; Chimusa, Emile E; Masimirembwa, Collen M CM; Ntsekhe, Mpiko M; Nhachi, Charles F B CFB; Dandara, Collet C
Warfarin Pharmacogenomics for Precision Medicine in Real-Life Clinical Practice in Southern Africa: Harnessing 73 Variants in 29 Pharmacogenes.
Omics : A Journal Of Integrative Biology
Muyambo, Sarudzai S; Ndadza, Arinao A; Soko, Nyarai D ND; Kruger, Bianca B; Kadzirange, Gerard G; Chimusa, Emile E; Masimirembwa, Collen M CM; Ntsekhe, Mpiko M; Nhachi, Charles F B CFB; Dandara, Collet C
Effect of CYP3A4, CYP3A5, MDR1 and POR Genetic Polymorphisms in Immunosuppressive Treatment in Chilean Kidney Transplanted Patients.
Frontiers In Pharmacology
Contreras-Castillo, Stephania S; Plaza, Anita A; Stojanova, Jana J; Navarro, Gustavo G; Carmona, Rodolfo R; Corvalán, Fernando F; Cerpa, Leslie L; Sandoval, Christopher C; Muñoz, Daniel D; Leiva, Marina M; Castañeda, Luis E LE; Farias, Nayaret N; Alvarez, Carolina C; Llull, Gabriel G; Mezzano, Sergio S; Ardiles, Leopoldo L; Varela, Nelson N; Rodríguez, María S MS; Flores, Claudio C; Cayún, Juan Pablo JP; Krall, Paola P; Quiñones, Luis A LA
SwissPKcdw - A clinical data warehouse for the optimization of pediatric dosing regimens.
Cpt: Pharmacometrics & Systems Pharmacology
Goers, Roland R; Coman Schmid, Diana D; Jäggi, Vera F VF; Paioni, Paolo P; Okoniewski, Michal J MJ; Parker, Althea A; Bangerter, Beat B; Georgakopoulou, Sofia S; Sengstag, Thierry T; Bielicki, Julia J; Tilen, Romy R; Vermeul, Swen S; Krämer, Stefanie D SD; Berger, Christoph C; Rinn, Bernd B; Meyer Zu Schwabedissen, Henriette E HE
SwissPKcdw - A clinical data warehouse for the optimization of pediatric dosing regimens.
Cpt: Pharmacometrics & Systems Pharmacology
Goers, Roland R; Coman Schmid, Diana D; Jäggi, Vera F VF; Paioni, Paolo P; Okoniewski, Michal J MJ; Parker, Althea A; Bangerter, Beat B; Georgakopoulou, Sofia S; Sengstag, Thierry T; Bielicki, Julia J; Tilen, Romy R; Vermeul, Swen S; Krämer, Stefanie D SD; Berger, Christoph C; Rinn, Bernd B; Meyer Zu Schwabedissen, Henriette E HE
CYP3A-status is associated with blood concentration and dose-requirement of tacrolimus in heart transplant recipients.
Scientific Reports
Déri, Máté M; Szakál-Tóth, Zsófia Z; Fekete, Ferenc F; Mangó, Katalin K; Incze, Evelyn E; Minus, Annamária A; Merkely, Béla B; Sax, Balázs B; Monostory, Katalin K
Effects of Cytochrome P450 and Transporter Polymorphisms on the Bioavailability and Safety of Dutasteride and Tamsulosin.
Frontiers In Pharmacology
Villapalos-García, Gonzalo G; Zubiaur, Pablo P; Navares-Gómez, Marcos M; Saiz-Rodríguez, Miriam M; Mejía-Abril, Gina G; Martín-Vílchez, Samuel S; Román, Manuel M; Ochoa, Dolores D; Abad-Santos, Francisco F
Variants in COMT, CYP3A5, CYP2B6, and ABCG2 Alter Quetiapine Pharmacokinetics.
Pharmaceutics
Zubiaur, Pablo P; Fernández-Campos, Paula P; Navares-Gómez, Marcos M; Soria-Chacartegui, Paula P; Villapalos-García, Gonzalo G; Román, Manuel M; Mejía-Abril, Gina G; Ochoa, Dolores D; Abad-Santos, Francisco F
Effect of Genetic Variation in CYP450 on Gonadal Impairment in a European Cohort of Female Childhood Cancer Survivors, Based on a Candidate Gene Approach: Results from the PanCareLIFE Study.
Cancers
van der Perk, M E Madeleine MEM; Broer, Linda L; Yasui, Yutaka Y; Robison, Leslie L LL; Hudson, Melissa M MM; Laven, Joop S E JSE; van der Pal, Helena J HJ; Tissing, Wim J E WJE; Versluys, Birgitta B; Bresters, Dorine D; Kaspers, Gertjan J L GJL; de Vries, Andrica C H ACH; Lambalk, Cornelis B CB; Overbeek, Annelies A; Loonen, Jacqueline J JJ; Beerendonk, Catharina C M CCM; Byrne, Julianne J; Berger, Claire C; Clemens, Eva E; Dirksen, Uta U; Falck Winther, Jeanette J; Fosså, Sophie D SD; Grabow, Desiree D; Muraca, Monica M; Kaiser, Melanie M; Kepák, Tomáš T; Kruseova, Jarmila J; Modan-Moses, Dalit D; Spix, Claudia C; Zolk, Oliver O; Kaatsch, Peter P; Krijthe, Jesse H JH; Kremer, Leontien C M LCM; Brooke, Russell J RJ; Baedke, Jessica L JL; van Schaik, Ron H N RHN; van den Anker, John N JN; Uitterlinden, André G AG; Bos, Annelies M E AME; van Leeuwen, Flora E FE; van Dulmen-den Broeder, Eline E; van der Kooi, Anne-Lotte L F ALF; van den Heuvel-Eibrink, Marry M MM; On Behalf Of The PanCareLIFE Consortium,
PriME-PGx: La Princesa University Hospital Multidisciplinary Initiative for the Implementation of Pharmacogenetics.
Journal Of Clinical Medicine
Zubiaur, Pablo P; Mejía-Abril, Gina G; Navares-Gómez, Marcos M; Villapalos-García, Gonzalo G; Soria-Chacartegui, Paula P; Saiz-Rodríguez, Miriam M; Ochoa, Dolores D; Abad-Santos, Francisco F