CYP3A4 c.520G>A ;(p.D174N)

Variant ID: 7-99367392-C-T

NM_017460.5(CYP3A4):c.520G>A;(p.D174N)

This variant was identified in 12 publications

View GRCh38 version.




Publications:


Why We Need to Take a Closer Look at Genetic Contributions to CYP3A Activity.

Frontiers In Pharmacology
Zhai, Qinglian Q; van der Lee, Maaike M; van Gelder, Teun T; Swen, Jesse J JJ
Publication Date: 2022

Variant appearance in text: rs4986908
PubMed Link: 35784699
Variant Present in the following documents:
  • fphar-13-912618.pdf
View BVdb publication page



Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Saudi Journal Of Biological Sciences
Aboul-Soud, Mourad A M MAM; Alzahrani, Alhussain J AJ; Mahmoud, Amer A
Publication Date: 2021-01

Variant appearance in text: rs4986908
PubMed Link: 33424349
Variant Present in the following documents:
  • mmc1.xlsx, sheet 1
View BVdb publication page



Targeted next generation sequencing as a tool for precision medicine.

Bmc Medical Genomics
Gulilat, Markus M; Lamb, Tyler T; Teft, Wendy A WA; Wang, Jian J; Dron, Jacqueline S JS; Robinson, John F JF; Tirona, Rommel G RG; Hegele, Robert A RA; Kim, Richard B RB; Schwarz, Ute I UI
Publication Date: 2019-06-03

Variant appearance in text: rs4986908
PubMed Link: 31159795
Variant Present in the following documents:
  • 12920_2019_527_MOESM1_ESM.xlsx, sheet 6
View BVdb publication page



Polymorphism in Cytochrome P450 3A4 Is Ethnicity Related.

Frontiers In Genetics
Guttman, Yelena Y; Nudel, Adi A; Kerem, Zohar Z
Publication Date: 2019

Variant appearance in text: rs4986908
PubMed Link: 30941162
Variant Present in the following documents:
  • Table_2.xlsx, sheet 5
  • Table_2.xlsx, sheet 7
  • Table_2.xlsx, sheet 8
  • Table_2.xlsx, sheet 4
  • Table_2.xlsx, sheet 6
  • Table_2.xlsx, sheet 2
  • Table_2.xlsx, sheet 3
View BVdb publication page



Population genetic difference of pharmacogenomic VIP gene variants in the Lisu population from Yunnan Province.

Medicine
Zhang, Chan C; Jiang, Xiaochun X; Chen, Wanlu W; Li, Qi Q; Yun, Fubin F; Yang, Xin X; Dai, Run R; Cheng, Yujing Y
Publication Date: 2018-12

Variant appearance in text: CYP3A4: Asp174Asn; rs4986908
PubMed Link: 30593137
Variant Present in the following documents:
  • medi-97-e13674.pdf
View BVdb publication page



iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports
Wang, Meng M; Wei, Liping L
Publication Date: 2016-08-16

Variant appearance in text: CYP3A4: D174N
PubMed Link: 27527004
Variant Present in the following documents:
  • srep31321-s3.xls, sheet 1
View BVdb publication page



Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One
Holehouse, Alex S AS; Naegle, Kristen M KM
Publication Date: 2015

Variant appearance in text: rs4986908
PubMed Link: 26659599
Variant Present in the following documents:
  • pone.0144692.s002.xlsx, sheet 1
View BVdb publication page



The Affymetrix DMET Plus platform reveals unique distribution of ADME-related variants in ethnic Arabs.

Disease Markers
Wakil, Salma M SM; Nguyen, Cao C; Muiya, Nzioka P NP; Andres, Editha E; Lykowska-Tarnowska, Agnieszka A; Baz, Batoul B; Tahir, Asma I AI; Meyer, Brian F BF; Morahan, Grant G; Dzimiri, Nduna N
Publication Date: 2015

Variant appearance in text: rs4986908
PubMed Link: 25802476
Variant Present in the following documents:
  • 542543.f1.xlsx, sheet 1
View BVdb publication page



The RPTEC/TERT1 cell line models key renal cell responses to the environmental toxicants, benzo[a]pyrene and cadmium.

Toxicology Reports
Simon, B R BR; Wilson, M J MJ; Wickliffe, J K JK
Publication Date: 2014

Variant appearance in text: rs4986908
PubMed Link: 25126521
Variant Present in the following documents:
  • mmc1.xls, sheet 1
View BVdb publication page



The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy.

Journal Of Personalized Medicine
Wang, Danxin D; Sadee, Wolfgang W
Publication Date: 2012-10-29

Variant appearance in text: CYP3A4: D174N; rs4986908
PubMed Link: 24466438
Variant Present in the following documents:
  • Main text
View BVdb publication page



Screening of Genetic Polymorphisms of CYP3A4 and CYP3A5 Genes.

The Korean Journal Of Physiology & Pharmacology : Official Journal Of The Korean Physiological Society And The Korean Society Of Pharmacology
Lee, Jin Sol JS; Cheong, Hyun Sub HS; Kim, Lyoung Hyo LH; Kim, Ji On JO; Seo, Doo Won DW; Kim, Young Hoon YH; Chung, Myeon Woo MW; Han, Soon Young SY; Shin, Hyoung Doo HD
Publication Date: 2013-12

Variant appearance in text: CYP3A4: D174N; rs4986908
PubMed Link: 24381495
Variant Present in the following documents:
  • kjpp-17-479.pdf
View BVdb publication page



Genotyping panel for assessing response to cancer chemotherapy.

Bmc Medical Genomics
Dai, Zunyan Z; Papp, Audrey C AC; Wang, Danxin D; Hampel, Heather H; Sadee, Wolfgang W
Publication Date: 2008-06-11

Variant appearance in text: rs4986908
PubMed Link: 18547414
Variant Present in the following documents:
  • 1755-8794-1-24-S1.xls, sheet 1
View BVdb publication page