Publications:

---

Why We Need to Take a Closer Look at Genetic Contributions to CYP3A Activity.

Frontiers In Pharmacology

Zhai, Qinglian Q; van der Lee, Maaike M; van Gelder, Teun T; Swen, Jesse J JJ

Publication Date: 2022

Variant appearance in text: CYP3A4: V170I; rs72552798

PubMed Link: 35784699

Variant Present in the following documents:

• Main text
• fphar-13-912618.pdf

View BVdb publication page

---

Enzymatic Activities of CYP3A4 Allelic Variants on Quinine 3-Hydroxylation In Vitro.

Frontiers In Pharmacology

Zhou, Xiao-Yang XY; Hu, Xiao-Xia XX; Wang, Chen-Chen CC; Lu, Xiang-Ran XR; Chen, Zhe Z; Liu, Qian Q; Hu, Guo-Xin GX; Cai, Jian-Ping JP

Publication Date: 2019

Variant appearance in text: CYP3A4: V170I

PubMed Link: 31214030

Variant Present in the following documents:

• Main text
• fphar-10-00591.pdf

View BVdb publication page

---

Polymorphism in Cytochrome P450 3A4 Is Ethnicity Related.

Frontiers In Genetics

Guttman, Yelena Y; Nudel, Adi A; Kerem, Zohar Z

Publication Date: 2019

Variant appearance in text: rs72552798

PubMed Link: 30941162

Variant Present in the following documents:

• Table_2.xlsx, sheet 8
• Table_2.xlsx, sheet 3
• Table_2.xlsx, sheet 7

View BVdb publication page

---

Influence of Genetic Variants on Steady-State Etonogestrel Concentrations Among Contraceptive Implant Users.

Obstetrics And Gynecology

Lazorwitz, Aaron A; Aquilante, Christina L CL; Oreschak, Kris K; Sheeder, Jeanelle J; Guiahi, Maryam M; Teal, Stephanie S

Publication Date: 2019-04

Variant appearance in text: rs72552798

PubMed Link: 30870275

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Functional assessment of CYP3A4 allelic variants on lidocaine metabolism in vitro.

Drug Design, Development And Therapy

Fang, Ping P; Tang, Peng-Fei PF; Xu, Ren-Ai RA; Zheng, Xiang X; Wen, Jian J; Bao, Su-Su SS; Cai, Jian-Ping JP; Hu, Guo-Xin GX

Publication Date: 2017

Variant appearance in text: CYP3A4: V170I

PubMed Link: 29263648

Variant Present in the following documents:

• Main text
• dddt-11-3503.pdf

View BVdb publication page

---

Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

Clinical Pharmacology And Therapeutics

Zhou, Y Y; Ingelman-Sundberg, M M; Lauschke, V M VM

Publication Date: 2017-10

Variant appearance in text: CYP3A4: V170I; rs72552798

PubMed Link: 28378927

Variant Present in the following documents:

• Main text
• CPT-102-688.pdf

View BVdb publication page

---

Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics

Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR

Publication Date: 2017-03

Variant appearance in text: rs72552798

PubMed Link: 27984508

Variant Present in the following documents:

• fpc-27-089-s005.xlsx, sheet 2

View BVdb publication page

---

GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: CYP3A4: V170I

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 1

View BVdb publication page

---

The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy.

Journal Of Personalized Medicine

Wang, Danxin D; Sadee, Wolfgang W

Publication Date: 2012-10-29

Variant appearance in text: CYP3A4: V170I; rs72552798

PubMed Link: 24466438

Variant Present in the following documents:

• Main text
• jpm-02-00175.pdf

View BVdb publication page

---

Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem.

Frontiers In Genetics

Klein, Kathrin K; Zanger, Ulrich M UM

Publication Date: 2013

Variant appearance in text: rs72552798

PubMed Link: 23444277

Variant Present in the following documents:

• Main text
• fgene-04-00012.pdf

View BVdb publication page

---

Reduced methylprednisolone clearance causing prolonged pharmacodynamics in a healthy subject was not associated with CYP3A5*3 allele or a change in diet composition.

Journal Of Clinical Pharmacology

Lee, Su-Jun SJ; Jusko, William J WJ; Salaita, Christine G CG; Calis, Karim A KA; Jann, Michael W MW; Spratlin, Vicky E VE; Goldstein, Joyce A JA; Hon, Yuen Yi YY

Publication Date: 2006-05

Variant appearance in text: CYP3A4: Val170Ile

PubMed Link: 16638735

Variant Present in the following documents:

• Main text

View BVdb publication page

---