Multiple signals at the extended 8p23 locus are associated with susceptibility to systemic lupus erythematosus.
Journal Of Medical Genetics
Demirci, F Yesim FY; Wang, Xingbin X; Morris, David L DL; Feingold, Eleanor E; Bernatsky, Sasha S; Pineau, Christian C; Clarke, Ann A; Ramsey-Goldman, Rosalind R; Manzi, Susan S; Vyse, Timothy J TJ; Kamboh, M I MI
Extension of GWAS results for lipid-related phenotypes to extreme obesity using electronic health record (EHR) data and the Metabochip.
Frontiers In Genetics
Parihar, Ankita A; Wood, G Craig GC; Chu, Xin X; Jin, Qunjan Q; Argyropoulos, George G; Still, Christopher D CD; Shuldiner, Alan R AR; Mitchell, Braxton D BD; Gerhard, Glenn S GS
LipidSeq: a next-generation clinical resequencing panel for monogenic dyslipidemias.
Journal Of Lipid Research
Johansen, Christopher T CT; Dubé, Joseph B JB; Loyzer, Melissa N MN; MacDonald, Austin A; Carter, David E DE; McIntyre, Adam D AD; Cao, Henian H; Wang, Jian J; Robinson, John F JF; Hegele, Robert A RA
Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases.
Bmc Medical Genetics
Huhn, Stefanie S; Bevier, Melanie M; Rudolph, Anja A; Pardini, Barbara B; Naccarati, Alessio A; Hein, Rebecca R; Hoffmeister, Michael M; Vodickova, Ludmila L; Novotny, Jan J; Brenner, Hermann H; Chang-Claude, Jenny J; Hemminki, Kari K; Vodicka, Pavel P; Försti, Asta A
Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance.
Diabetes
De Silva, N Maneka G NM; Freathy, Rachel M RM; Palmer, Tom M TM; Donnelly, Louise A LA; Luan, Jian'an J; Gaunt, Tom T; Langenberg, Claudia C; Weedon, Michael N MN; Shields, Beverley B; Knight, Beatrice A BA; Ward, Kirsten J KJ; Sandhu, Manjinder S MS; Harbord, Roger M RM; McCarthy, Mark I MI; Smith, George Davey GD; Ebrahim, Shah S; Hattersley, Andrew T AT; Wareham, Nicholas N; Lawlor, Debbie A DA; Morris, Andrew D AD; Palmer, Colin N A CN; Frayling, Timothy M TM
Association of common DNA sequence variants at 33 genetic loci with blood lipids in individuals of African ancestry from Jamaica.
Human Genetics
Gupta, R R; Ejebe, K K; Butler, J J; Lettre, G G; Lyon, H H; Guiducci, C C; Wilks, R R; Bennett, F F; Forrester, T T; Tayo, B B; Musunuru, K K; Hirschhorn, J J; Kathiresan, S S; Cooper, R S RS; McKenzie, C A CA
Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.
Plos Genetics
Smith, Erin N EN; Chen, Wei W; Kähönen, Mika M; Kettunen, Johannes J; Lehtimäki, Terho T; Peltonen, Leena L; Raitakari, Olli T OT; Salem, Rany M RM; Schork, Nicholas J NJ; Shaw, Marian M; Srinivasan, Sathanur R SR; Topol, Eric J EJ; Viikari, Jorma S JS; Berenson, Gerald S GS; Murray, Sarah S SS
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.
Nature Genetics
Johansen, Christopher T CT; Wang, Jian J; Lanktree, Matthew B MB; Cao, Henian H; McIntyre, Adam D AD; Ban, Matthew R MR; Martins, Rebecca A RA; Kennedy, Brooke A BA; Hassell, Reina G RG; Visser, Maartje E ME; Schwartz, Stephen M SM; Voight, Benjamin F BF; Elosua, Roberto R; Salomaa, Veikko V; O'Donnell, Christopher J CJ; Dallinga-Thie, Geesje M GM; Anand, Sonia S SS; Yusuf, Salim S; Huff, Murray W MW; Kathiresan, Sekar S; Hegele, Robert A RA
Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.
Plos Genetics
Scherag, André A; Dina, Christian C; Hinney, Anke A; Vatin, Vincent V; Scherag, Susann S; Vogel, Carla I G CI; Müller, Timo D TD; Grallert, Harald H; Wichmann, H-Erich HE; Balkau, Beverley B; Heude, Barbara B; Jarvelin, Marjo-Riitta MR; Hartikainen, Anna-Liisa AL; Levy-Marchal, Claire C; Weill, Jacques J; Delplanque, Jérôme J; Körner, Antje A; Kiess, Wieland W; Kovacs, Peter P; Rayner, Nigel W NW; Prokopenko, Inga I; McCarthy, Mark I MI; Schäfer, Helmut H; Jarick, Ivonne I; Boeing, Heiner H; Fisher, Eva E; Reinehr, Thomas T; Heinrich, Joachim J; Rzehak, Peter P; Berdel, Dietrich D; Borte, Michael M; Biebermann, Heike H; Krude, Heiko H; Rosskopf, Dieter D; Rimmbach, Christian C; Rief, Winfried W; Fromme, Tobias T; Klingenspor, Martin M; Schürmann, Annette A; Schulz, Nadja N; Nöthen, Markus M MM; Mühleisen, Thomas W TW; Erbel, Raimund R; Jöckel, Karl-Heinz KH; Moebus, Susanne S; Boes, Tanja T; Illig, Thomas T; Froguel, Philippe P; Hebebrand, Johannes J; Meyre, David D
Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples.
Circulation. Cardiovascular Genetics
Weissglas-Volkov, Daphna D; Aguilar-Salinas, Carlos A CA; Sinsheimer, Janet S JS; Riba, Laura L; Huertas-Vazquez, Adriana A; Ordoñez-Sánchez, Maria L ML; Rodriguez-Guillen, Rosario R; Cantor, Rita M RM; Tusie-Luna, Teresa T; Pajukanta, Päivi P
Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.
Plos Genetics
Chasman, Daniel I DI; Paré, Guillaume G; Mora, Samia S; Hopewell, Jemma C JC; Peloso, Gina G; Clarke, Robert R; Cupples, L Adrienne LA; Hamsten, Anders A; Kathiresan, Sekar S; Mälarstig, Anders A; Ordovas, José M JM; Ripatti, Samuli S; Parker, Alex N AN; Miletich, Joseph P JP; Ridker, Paul M PM
The effect of a novel intergenic polymorphism (rs11774572) on HDL-cholesterol concentrations depends on TaqIB polymorphism in the cholesterol ester transfer protein gene.
Nutrition, Metabolism, And Cardiovascular Diseases : Nmcd
Junyent, M M; Lee, Y-C YC; Smith, C E CE; Arnett, D K DK; Tsai, M Y MY; Kabagambe, E K EK; Straka, R J RJ; Province, M M; An, P P; Lai, C-Q CQ; Parnell, L D LD; Shen, J J; Borecki, I I; Ordovas, J M JM
Common variants at 30 loci contribute to polygenic dyslipidemia.
Nature Genetics
Kathiresan, Sekar S; Willer, Cristen J CJ; Peloso, Gina M GM; Demissie, Serkalem S; Musunuru, Kiran K; Schadt, Eric E EE; Kaplan, Lee L; Bennett, Derrick D; Li, Yun Y; Tanaka, Toshiko T; Voight, Benjamin F BF; Bonnycastle, Lori L LL; Jackson, Anne U AU; Crawford, Gabriel G; Surti, Aarti A; Guiducci, Candace C; Burtt, Noel P NP; Parish, Sarah S; Clarke, Robert R; Zelenika, Diana D; Kubalanza, Kari A KA; Morken, Mario A MA; Scott, Laura J LJ; Stringham, Heather M HM; Galan, Pilar P; Swift, Amy J AJ; Kuusisto, Johanna J; Bergman, Richard N RN; Sundvall, Jouko J; Laakso, Markku M; Ferrucci, Luigi L; Scheet, Paul P; Sanna, Serena S; Uda, Manuela M; Yang, Qiong Q; Lunetta, Kathryn L KL; Dupuis, Josée J; de Bakker, Paul I W PI; O'Donnell, Christopher J CJ; Chambers, John C JC; Kooner, Jaspal S JS; Hercberg, Serge S; Meneton, Pierre P; Lakatta, Edward G EG; Scuteri, Angelo A; Schlessinger, David D; Tuomilehto, Jaakko J; Collins, Francis S FS; Groop, Leif L; Altshuler, David D; Collins, Rory R; Lathrop, G Mark GM; Melander, Olle O; Salomaa, Veikko V; Peltonen, Leena L; Orho-Melander, Marju M; Ordovas, Jose M JM; Boehnke, Michael M; Abecasis, Gonçalo R GR; Mohlke, Karen L KL; Cupples, L Adrienne LA