Three-dimensional microenvironment regulates gene expression, function, and tight junction dynamics of iPSC-derived blood-brain barrier microvessels.
Fluids And Barriers Of The Cns
Linville, Raleigh M RM; Sklar, Matthew B MB; Grifno, Gabrielle N GN; Nerenberg, Renée F RF; Zhou, Justin J; Ye, Robert R; DeStefano, Jackson G JG; Guo, Zhaobin Z; Jha, Ria R; Jamieson, John J JJ; Zhao, Nan N; Searson, Peter C PC
Keller, T C Stevenson TCS; Lechauve, Christophe C; Keller, Alexander S AS; Broseghini-Filho, Gilson Brás GB; Butcher, Joshua T JT; Askew Page, Henry R HR; Islam, Aditi A; Tan, Zhe Yin ZY; DeLalio, Leon J LJ; Brooks, Steven S; Sharma, Poonam P; Hong, Kwangseok K; Xu, Wenhao W; Padilha, Alessandra Simão AS; Ruddiman, Claire A CA; Best, Angela K AK; Macal, Edgar E; Kim-Shapiro, Daniel B DB; Christ, George G; Yan, Zhen Z; Cortese-Krott, Miriam M MM; Ricart, Karina K; Patel, Rakesh R; Bender, Timothy P TP; Sonkusare, Swapnil K SK; Weiss, Mitchell J MJ; Ackerman, Hans H; Columbus, Linda L; Isakson, Brant E BE
Acute lymphoblastic leukemia-derived extracellular vesicles affect quiescence of hematopoietic stem and progenitor cells.
Cell Death & Disease
Georgievski, Aleksandra A; Michel, Anaïs A; Thomas, Charles C; Mlamla, Zandile Z; Pais de Barros, Jean-Paul JP; Lemaire-Ewing, Stéphanie S; Garrido, Carmen C; Quéré, Ronan R
Bacillus Calmette-Guérin Treatment Changes the Tumor Microenvironment of Non-Muscle-Invasive Bladder Cancer.
Frontiers In Oncology
Su, Fei F; Liu, Ming M; Zhang, Wei W; Tang, Min M; Zhang, Jinsong J; Li, Hexin H; Zou, Lihui L; Zhang, Rui R; Liu, Yudong Y; Li, Lin L; Ma, Jie J; Zhang, Yaqun Y; Chen, Meng M; Xiao, Fei F
Selective Inhibition of the C-Domain of ACE (Angiotensin-Converting Enzyme) Combined With Inhibition of NEP (Neprilysin): A Potential New Therapy for Hypertension.
Hypertension (Dallas, Tex. : 1979)
Alves-Lopes, Rhéure R; Montezano, Augusto C AC; Neves, Karla B KB; Harvey, Adam A; Rios, Francisco J FJ; Skiba, Dominik S DS; Arendse, Lauren B LB; Guzik, Tomasz J TJ; Graham, Delyth D; Poglitsch, Marko M; Sturrock, Edward E; Touyz, Rhian M RM
Secondary resistance to anti-EGFR therapy by transcriptional reprogramming in patient-derived colorectal cancer models.
Genome Medicine
Vangala, Deepak D; Ladigan, Swetlana S; Liffers, Sven T ST; Noseir, Soha S; Maghnouj, Abdelouahid A; Götze, Tina-Maria TM; Verdoodt, Berlinda B; Klein-Scory, Susanne S; Godfrey, Laura L; Zowada, Martina K MK; Huerta, Mario M; Edelstein, Daniel L DL; de Villarreal, Jaime Martinez JM; Marqués, Miriam M; Kumbrink, Jörg J; Jung, Andreas A; Schiergens, Tobias T; Werner, Jens J; Heinemann, Volker V; Stintzing, Sebastian S; Lindoerfer, Doris D; Mansmann, Ulrich U; Pohl, Michael M; Teschendorf, Christian C; Bernhardt, Christiane C; Wolters, Heiner H; Stern, Josef J; Usta, Selami S; Viebahn, Richard R; Admard, Jacob J; Casadei, Nicolas N; Fröhling, Stefan S; Ball, Claudia R CR; Siveke, Jens T JT; Glimm, Hanno H; Tannapfel, Andrea A; Schmiegel, Wolff W; Hahn, Stephan A SA
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs: a single molecule perspective.
Biorxiv : The Preprint Server For Biology
Seifert, Mona M; Bera, Subhas Chandra SC; van Nies, Pauline P; Kirchdoerfer, Robert N RN; Shannon, Ashleigh A; Le, Thi-Tuyet-Nhung TT; Meng, Xiangzhi X; Xia, Hongjie H; Wood, James M JM; Harris, Lawrence D LD; Papini, Flávia S FS; Arnold, Jamie J JJ; Almo, Steven C SC; Grove, Tyler L TL; Shi, Pei-Yong PY; Xiang, Yan Y; Canard, Bruno B; Depken, Martin M; Cameron, Craig E CE; Dulin, David D
Design of a companion bioinformatic tool to detect the emergence and geographical distribution of SARS-CoV-2 Spike protein genetic variants.
Journal Of Translational Medicine
Massacci, Alice A; Sperandio, Eleonora E; D'Ambrosio, Lorenzo L; Maffei, Mariano M; Palombo, Fabio F; Aurisicchio, Luigi L; Ciliberto, Gennaro G; Pallocca, Matteo M
Integrated molecular drivers coordinate biological and clinical states in melanoma.
Nature Genetics
Conway, Jake R JR; Dietlein, Felix F; Taylor-Weiner, Amaro A; AlDubayan, Saud S; Vokes, Natalie N; Keenan, Tanya T; Reardon, Brendan B; He, Meng Xiao MX; Margolis, Claire A CA; Weirather, Jason L JL; Haq, Rizwan R; Schilling, Bastian B; Stephen Hodi, F F; Schadendorf, Dirk D; Liu, David D; Van Allen, Eliezer M EM
Expression and Mutation Patterns of PBRM1, BAP1 and SETD2 Mirror Specific Evolutionary Subtypes in Clear Cell Renal Cell Carcinoma.
Neoplasia (New York, N.Y.)
Bihr, Svenja S; Ohashi, Riuko R; Moore, Ariane L AL; Rüschoff, Jan H JH; Beisel, Christian C; Hermanns, Thomas T; Mischo, Axel A; Corrò, Claudia C; Beyer, Jörg J; Beerenwinkel, Niko N; Moch, Holger H; Schraml, Peter P
The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease.
Cancer Cell
Kosack, Lindsay L; Wingelhofer, Bettina B; Popa, Alexandra A; Orlova, Anna A; Agerer, Benedikt B; Vilagos, Bojan B; Majek, Peter P; Parapatics, Katja K; Lercher, Alexander A; Ringler, Anna A; Klughammer, Johanna J; Smyth, Mark M; Khamina, Kseniya K; Baazim, Hatoon H; de Araujo, Elvin D ED; Rosa, David A DA; Park, Jisung J; Tin, Gary G; Ahmar, Siawash S; Gunning, Patrick T PT; Bock, Christoph C; Siddle, Hannah V HV; Woods, Gregory M GM; Kubicek, Stefan S; Murchison, Elizabeth P EP; Bennett, Keiryn L KL; Moriggl, Richard R; Bergthaler, Andreas A
Recurrent inactivating RASA2 mutations in melanoma.
Nature Genetics
Arafeh, Rand R; Qutob, Nouar N; Emmanuel, Rafi R; Keren-Paz, Alona A; Madore, Jason J; Elkahloun, Abdel A; Wilmott, James S JS; Gartner, Jared J JJ; Di Pizio, Antonella A; Winograd-Katz, Sabina S; Sindiri, Sivasish S; Rotkopf, Ron R; Dutton-Regester, Ken K; Johansson, Peter P; Pritchard, Antonia L AL; Waddell, Nicola N; Hill, Victoria K VK; Lin, Jimmy C JC; Hevroni, Yael Y; Rosenberg, Steven A SA; Khan, Javed J; Ben-Dor, Shifra S; Niv, Masha Y MY; Ulitsky, Igor I; Mann, Graham J GJ; Scolyer, Richard A RA; Hayward, Nicholas K NK; Samuels, Yardena Y
Complex archaea that bridge the gap between prokaryotes and eukaryotes.
Nature
Spang, Anja A; Saw, Jimmy H JH; Jørgensen, Steffen L SL; Zaremba-Niedzwiedzka, Katarzyna K; Martijn, Joran J; Lind, Anders E AE; van Eijk, Roel R; Schleper, Christa C; Guy, Lionel L; Ettema, Thijs J G TJG