Mice expressing fluorescent PAR2 reveal that endocytosis mediates colonic inflammation and pain.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Latorre, Rocco R; Hegron, Alan A; Peach, Chloe J CJ; Teng, Shavonne S; Tonello, Raquel R; Retamal, Jeffri S JS; Klein-Cloud, Rafael R; Bok, Diana D; Jensen, Dane D DD; Gottesman-Katz, Lena L; Rientjes, Jeanette J; Veldhuis, Nicholas A NA; Poole, Daniel P DP; Schmidt, Brian L BL; Pothoulakis, Charalabos H CH; Rankin, Carl C; Xie, Ying Y; Koon, Hon Wai HW; Bunnett, Nigel W NW
Mice expressing fluorescent PAR2 reveal that endocytosis mediates colonic inflammation and pain.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Latorre, Rocco R; Hegron, Alan A; Peach, Chloe J CJ; Teng, Shavonne S; Tonello, Raquel R; Retamal, Jeffri S JS; Klein-Cloud, Rafael R; Bok, Diana D; Jensen, Dane D DD; Gottesman-Katz, Lena L; Rientjes, Jeanette J; Veldhuis, Nicholas A NA; Poole, Daniel P DP; Schmidt, Brian L BL; Pothoulakis, Charalabos H CH; Rankin, Carl C; Xie, Ying Y; Koon, Hon Wai HW; Bunnett, Nigel W NW
Increases in cytosolic Ca2+ induce dynamin- and calcineurin-dependent internalisation of CFTR.
Cellular And Molecular Life Sciences : Cmls
Patel, Waseema W; Moore, Patrick J PJ; Sassano, M Flori MF; Lopes-Pacheco, Miquéias M; Aleksandrov, Andrei A AA; Amaral, Margarida D MD; Tarran, Robert R; Gray, Michael A MA
Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture.
The Journal Of Cell Biology
Varlakhanova, Natalia V NV; Alvarez, Frances J D FJD; Brady, Tyler M TM; Tornabene, Bryan A BA; Hosford, Christopher J CJ; Chappie, Joshua S JS; Zhang, Peijun P; Ford, Marijn G J MGJ
Dynamin-2 mutations linked to Centronuclear Myopathy impair actin-dependent trafficking in muscle cells.
Scientific Reports
González-Jamett, Arlek M AM; Baez-Matus, Ximena X; Olivares, María José MJ; Hinostroza, Fernando F; Guerra-Fernández, Maria José MJ; Vasquez-Navarrete, Jacqueline J; Bui, Mai Thao MT; Guicheney, Pascale P; Romero, Norma Beatriz NB; Bevilacqua, Jorge A JA; Bitoun, Marc M; Caviedes, Pablo P; Cárdenas, Ana M AM
Recombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels.
Scientific Reports
Bobak, Nicole N; Feliciangeli, Sylvain S; Chen, Cheng-Chang CC; Ben Soussia, Ismail I; Bittner, Stefan S; Pagnotta, Sophie S; Ruck, Tobias T; Biel, Martin M; Wahl-Schott, Christian C; Grimm, Christian C; Meuth, Sven G SG; Lesage, Florian F
A rapid and affordable screening platform for membrane protein trafficking.
Bmc Biology
Snyder, Joshua C JC; Pack, Thomas F TF; Rochelle, Lauren K LK; Chakraborty, Subhasish K SK; Zhang, Ming M; Eaton, Andrew W AW; Bai, Yushi Y; Ernst, Lauren A LA; Barak, Larry S LS; Waggoner, Alan S AS; Caron, Marc G MG
Microtubule motors power plasma membrane tubulation in clathrin-independent endocytosis.
Traffic (Copenhagen, Denmark)
Day, Charles A CA; Baetz, Nicholas W NW; Copeland, Courtney A CA; Kraft, Lewis J LJ; Han, Bing B; Tiwari, Ajit A; Drake, Kimberly R KR; De Luca, Heidi H; Chinnapen, Daniel J-F DJ; Davidson, Michael W MW; Holmes, Randall K RK; Jobling, Michael G MG; Schroer, Trina A TA; Lencer, Wayne I WI; Kenworthy, Anne K AK
Flat clathrin lattices: stable features of the plasma membrane.
Molecular Biology Of The Cell
Grove, Joe J; Metcalf, Daniel J DJ; Knight, Alex E AE; Wavre-Shapton, Silène T ST; Sun, Tony T; Protonotarios, Emmanouil D ED; Griffin, Lewis D LD; Lippincott-Schwartz, Jennifer J; Marsh, Mark M
Trafficking of the Menkes copper transporter ATP7A is regulated by clathrin-, AP-2-, AP-1-, and Rab22-dependent steps.
Molecular Biology Of The Cell
Holloway, Zoe G ZG; Velayos-Baeza, Antonio A; Howell, Gareth J GJ; Levecque, Clotilde C; Ponnambalam, Sreenivasan S; Sztul, Elizabeth E; Monaco, Anthony P AP
Identification of an endocytosis motif in an intracellular loop of Wntless protein, essential for its recycling and the control of Wnt protein signaling.
The Journal Of Biological Chemistry
Gasnereau, Isabelle I; Herr, Patrick P; Chia, Pei Zhi Cheryl PZ; Basler, Konrad K; Gleeson, Paul A PA
The cytoskeletal protein Ndel1 regulates dynamin 2 GTPase activity.
Plos One
Chansard, Mathieu M; Wang, Jian J; Tran, Hong Chi HC; Neumayer, Gernot G; Shim, Su Yeon SY; Park, Young-Un YU; Belzil, Camille C; Le, Hoa Thi HT; Park, Sang Ki SK; Nguyen, Minh Dang MD
HIV-1 Nef binds a subpopulation of MHC-I throughout its trafficking itinerary and down-regulates MHC-I by perturbing both anterograde and retrograde trafficking.
The Journal Of Biological Chemistry
Yi, Ling L; Rosales, Tilman T; Rose, Jeremy J JJ; Chowdhury, Bhabadeb B; Chaudhury, Bhabhadeb B; Knutson, Jay R JR; Venkatesan, Sundararajan S
HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits.
Nature Immunology
Xu, Weifeng W; Santini, Paul A PA; Sullivan, John S JS; He, Bing B; Shan, Meimei M; Ball, Susan C SC; Dyer, Wayne B WB; Ketas, Thomas J TJ; Chadburn, Amy A; Cohen-Gould, Leona L; Knowles, Daniel M DM; Chiu, April A; Sanders, Rogier W RW; Chen, Kang K; Cerutti, Andrea A
Opposite roles of FAP-1 and dynamin in the regulation of Fas (CD95) translocation to the cell surface and susceptibility to Fas ligand-mediated apoptosis.
The Journal Of Biological Chemistry
Ivanov, Vladimir N VN; Ronai, Ze'ev Z; Hei, Tom K TK
Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells.
Molecular And Cellular Biology
Parsons, Maddy M; Monypenny, James J; Ameer-Beg, Simon M SM; Millard, Thomas H TH; Machesky, Laura M LM; Peter, Marion M; Keppler, Melanie D MD; Schiavo, Giampietro G; Watson, Rose R; Chernoff, Jonathan J; Zicha, Daniel D; Vojnovic, Borivoj B; Ng, Tony T
Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent.
The Embo Journal
Watson, Robert T RT; Khan, Ahmir H AH; Furukawa, Megumi M; Hou, June Chunqiu JC; Li, Lin L; Kanzaki, Makoto M; Okada, Shuichi S; Kandror, Konstantin V KV; Pessin, Jeffrey E JE
Direct binding of human immunodeficiency virus type 1 Nef to the major histocompatibility complex class I (MHC-I) cytoplasmic tail disrupts MHC-I trafficking.
Journal Of Virology
Williams, Maya M; Roeth, Jeremiah F JF; Kasper, Matthew R MR; Fleis, Rebekah I RI; Przybycin, Chris G CG; Collins, Kathleen L KL