TG c.436A>C ;(p.M146L)

Variant ID: 8-133883754-A-C

NM_003235.4(TG):c.436A>C;(p.M146L)

This variant was identified in 24 publications

View GRCh38 version.




Publications:


HaploCoV: unsupervised classification and rapid detection of novel emerging variants of SARS-CoV-2.

Communications Biology
Chiara, Matteo M; Horner, David S DS; Ferrandi, Erika E; Gissi, Carmela C; Pesole, Graziano G
Publication Date: 2023-04-22

Variant appearance in text: TG: 436A>C
PubMed Link: 37087497
Variant Present in the following documents:
  • 42003_2023_4784_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Rickettsia felis DNA recovered from a child who lived in southern Africa 2000 years ago.

Communications Biology
Rifkin, Riaan F RF; Vikram, Surendra S; Alcorta, Jaime J; Ramond, Jean-Baptiste JB; Cowan, Don A DA; Jakobsson, Mattias M; Schlebusch, Carina M CM; Lombard, Marlize M
Publication Date: 2023-03-03

Variant appearance in text: TG: 436A>C
PubMed Link: 36869137
Variant Present in the following documents:
  • 42003_2023_4582_MOESM4_ESM.xlsx, sheet 8
  • 42003_2023_4582_MOESM4_ESM.xlsx, sheet 9
View BVdb publication page



An Ultra-Low Dose of ∆9-Tetrahydrocannabinol Alleviates Alzheimer's Disease-Related Cognitive Impairments and Modulates TrkB Receptor Expression in a 5XFAD Mouse Model.

International Journal Of Molecular Sciences
Nitzan, Keren K; Ellenbogen, Leah L; Bentulila, Ziv Z; David, Dekel D; Franko, Motty M; Break, Emanuela P EP; Zoharetz, Michal M; Shamir, Alon A; Sarne, Yosef Y; Doron, Ravid R
Publication Date: 2022-08-21

Variant appearance in text: TG: M146L
PubMed Link: 36012711
Variant Present in the following documents:
  • ijms-23-09449.pdf
View BVdb publication page



Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes.

Nature Communications
Akbari, Parsa P; Sosina, Olukayode A OA; Bovijn, Jonas J; Landheer, Karl K; Nielsen, Jonas B JB; Kim, Minhee M; Aykul, Senem S; De, Tanima T; Haas, Mary E ME; Hindy, George G; Lin, Nan N; Dinsmore, Ian R IR; Luo, Jonathan Z JZ; Hectors, Stefanie S; Geraghty, Benjamin B; Germino, Mary M; Panagis, Lampros L; Parasoglou, Prodromos P; Walls, Johnathon R JR; Halasz, Gabor G; Atwal, Gurinder S GS; , ; , ; Jones, Marcus M; LeBlanc, Michelle G MG; Still, Christopher D CD; Carey, David J DJ; Giontella, Alice A; Orho-Melander, Marju M; Berumen, Jaime J; Kuri-Morales, Pablo P; Alegre-Díaz, Jesus J; Torres, Jason M JM; Emberson, Jonathan R JR; Collins, Rory R; Rader, Daniel J DJ; Zambrowicz, Brian B; Murphy, Andrew J AJ; Balasubramanian, Suganthi S; Overton, John D JD; Reid, Jeffrey G JG; Shuldiner, Alan R AR; Cantor, Michael M; Abecasis, Goncalo R GR; Ferreira, Manuel A R MAR; Sleeman, Mark W MW; Gusarova, Viktoria V; Altarejos, Judith J; Harris, Charles C; Economides, Aris N AN; Idone, Vincent V; Karalis, Katia K; Della Gatta, Giusy G; Mirshahi, Tooraj T; Yancopoulos, George D GD; Melander, Olle O; Marchini, Jonathan J; Tapia-Conyer, Roberto R; Locke, Adam E AE; Baras, Aris A; Verweij, Niek N; Lotta, Luca A LA
Publication Date: 2022-08-23

Variant appearance in text: TG: 436A>C
PubMed Link: 35999217
Variant Present in the following documents:
  • 41467_2022_32398_MOESM4_ESM.xlsx, sheet 4
View BVdb publication page



Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer's disease.

Journal Of Neuroinflammation
Banik, Avijit A; Amaradhi, Radhika R; Lee, Daniel D; Sau, Michael M; Wang, Wenyi W; Dingledine, Raymond R; Ganesh, Thota T
Publication Date: 2021-11-20

Variant appearance in text: TG: M146L
PubMed Link: 34801055
Variant Present in the following documents:
  • Main text
View BVdb publication page



Effects of far infrared light on Alzheimer's disease-transgenic mice.

Plos One
Fukui, Koji K; Kimura, Shunsuke S; Kato, Yugo Y; Kohno, Masahiro M
Publication Date: 2021

Variant appearance in text: TG: M146L
PubMed Link: 34138944
Variant Present in the following documents:
  • pone.0253320.pdf
View BVdb publication page



Genomics of an endemic cystic fibrosis Burkholderia multivorans strain reveals low within-patient evolution but high between-patient diversity.

Plos Pathogens
Lood, Cédric C; Peeters, Charlotte C; Lamy-Besnier, Quentin Q; Wagemans, Jeroen J; De Vos, Daniel D; Proesmans, Marijke M; Pirnay, Jean-Paul JP; Echahidi, Fedoua F; Piérard, Denis D; Thimmesch, Matthieu M; Boeras, Anca A; Lagrou, Katrien K; De Canck, Evelien E; De Wachter, Elke E; van Noort, Vera V; Lavigne, Rob R; Vandamme, Peter P
Publication Date: 2021-03

Variant appearance in text: TG: 436A>C
PubMed Link: 33720991
Variant Present in the following documents:
  • ppat.1009418.s005.xlsx, sheet 9
View BVdb publication page



Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model.

Plos One
Kim, DaWon D; Lee, Jeong Hwa JH; Kim, Hye Yun HY; Shin, Jisu J; Kim, Kyeonghwan K; Lee, Sejin S; Park, Jinwoo J; Kim, JinIkyon J; Kim, YoungSoo Y
Publication Date: 2020

Variant appearance in text: TG: M146L
PubMed Link: 33362250
Variant Present in the following documents:
  • pone.0243041.pdf
View BVdb publication page



K-Ras-Activated Cells Can Develop into Lung Tumors When Runx3-Mediated Tumor Suppressor Pathways Are Abrogated.

Molecules And Cells
Lee, You-Soub YS; Lee, Ja-Yeol JY; Song, Soo-Hyun SH; Kim, Da-Mi DM; Lee, Jung-Won JW; Chi, Xin-Zi XZ; Ito, Yoshiaki Y; Bae, Suk-Chul SC
Publication Date: 2020-10-31

Variant appearance in text: TG: 436A>C; Met146Leu
PubMed Link: 33115981
Variant Present in the following documents:
  • molce-43-889_Supple.xlsx, sheet 1
View BVdb publication page



Inhibition of Colony-Stimulating Factor 1 Receptor by PLX3397 Prevents Amyloid Beta Pathology and Rescues Dopaminergic Signaling in Aging 5xFAD Mice.

International Journal Of Molecular Sciences
Son, Yeonghoon Y; Jeong, Ye Ji YJ; Shin, Na-Rae NR; Oh, Se Jong SJ; Nam, Kyung Rok KR; Choi, Hyung-Do HD; Choi, Jae Yong JY; Lee, Hae-June HJ
Publication Date: 2020-08-03

Variant appearance in text: TG: M146L
PubMed Link: 32756440
Variant Present in the following documents:
  • ijms-21-05553.pdf
View BVdb publication page



2-Hydroxy-Docosahexaenoic Acid Is Converted Into Heneicosapentaenoic Acid via α-Oxidation: Implications for Alzheimer's Disease Therapy.

Frontiers In Cell And Developmental Biology
Parets, Sebastià S; Irigoyen, Ángel Á; Ordinas, Margarita M; Cabot, Joan J; Miralles, Marc M; Arbona, Laura L; Péter, Mária M; Balogh, Gábor G; Fernández-García, Paula P; Busquets, Xavier X; Lladó, Victoria V; Escribá, Pablo V PV; Torres, Manuel M
Publication Date: 2020

Variant appearance in text: TG: M146L
PubMed Link: 32292781
Variant Present in the following documents:
  • Main text
  • fcell-08-00164.pdf
View BVdb publication page



Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease.

Plos One
Kwak, Da Eun DE; Ko, Taeho T; Koh, Han Seok HS; Ji, Yong Woo YW; Shin, Jisu J; Kim, Kyeonghwan K; Kim, Hye Yun HY; Lee, Hyung-Keun HK; Kim, YoungSoo Y
Publication Date: 2020

Variant appearance in text: TG: M146L
PubMed Link: 31923257
Variant Present in the following documents:
  • pone.0227618.pdf
View BVdb publication page



Inhibition of Polo-like kinase 2 ameliorates pathogenesis in Alzheimer's disease model mice.

Plos One
Lee, Ji Soo JS; Lee, Yeunkum Y; André, Emily A EA; Lee, Kea Joo KJ; Nguyen, Thien T; Feng, Yang Y; Jia, Nuo N; Harris, Brent T BT; Burns, Mark P MP; Pak, Daniel T S DTS
Publication Date: 2019

Variant appearance in text: TG: M146L
PubMed Link: 31306446
Variant Present in the following documents:
  • pone.0219691.pdf
View BVdb publication page



Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis.

Genome Research
Goodwin, Leslie O LO; Splinter, Erik E; Davis, Tiffany L TL; Urban, Rachel R; He, Hao H; Braun, Robert E RE; Chesler, Elissa J EJ; Kumar, Vivek V; van Min, Max M; Ndukum, Juliet J; Philip, Vivek M VM; Reinholdt, Laura G LG; Svenson, Karen K; White, Jacqueline K JK; Sasner, Michael M; Lutz, Cathleen C; Murray, Stephen A SA
Publication Date: 2019-03

Variant appearance in text: TG: M146L
PubMed Link: 30659012
Variant Present in the following documents:
  • 494.pdf
View BVdb publication page



Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo.

Cell Reports
Jeong, Mira M; Park, Hyun Jung HJ; Celik, Hamza H; Ostrander, Elizabeth L EL; Reyes, Jaime M JM; Guzman, Anna A; Rodriguez, Benjamin B; Lei, Yong Y; Lee, Yeojin Y; Ding, Lei L; Guryanova, Olga A OA; Li, Wei W; Goodell, Margaret A MA; Challen, Grant A GA
Publication Date: 2018-04-03

Variant appearance in text: TG: 436A>C
PubMed Link: 29617651
Variant Present in the following documents:
  • NIHMS958971-supplement-5.xlsx, sheet 2
View BVdb publication page



Whole-Genome Resequencing Identifies the Molecular Genetic Cause for the Absence of a Gy5 Glycinin Protein in Soybean PI 603408.

G3 (Bethesda, Md.)
Gillman, Jason D JD; Kim, Won-Seok WS; Song, Bo B; Oehrle, Nathan W NW; Tawari, Nilesh R NR; Liu, Shanshan S; Krishnan, Hari B HB
Publication Date: 2017-07-05

Variant appearance in text: TG: Met146Leu
PubMed Link: 28592556
Variant Present in the following documents:
  • 2345FileS1.xlsx, sheet 1
View BVdb publication page



Involvement of the Bradykinin B1 Receptor in Microglial Activation: In Vitro and In Vivo Studies.

Frontiers In Endocrinology
Asraf, Keren K; Torika, Nofar N; Danon, Abraham A; Fleisher-Berkovich, Sigal S
Publication Date: 2017

Variant appearance in text: TG: M146L
PubMed Link: 28469598
Variant Present in the following documents:
  • Main text
  • fendo-08-00082.pdf
View BVdb publication page



Amyloid Plaque-Associated Oxidative Degradation of Uniformly Radiolabeled Arachidonic Acid.

Acs Chemical Neuroscience
Furman, Ran R; Murray, Ian V J IV; Schall, Hayley E HE; Liu, Qiwei Q; Ghiwot, Yonatan Y; Axelsen, Paul H PH
Publication Date: 2016-03-16

Variant appearance in text: TG: M146L
PubMed Link: 26800372
Variant Present in the following documents:
  • Main text
View BVdb publication page



Acute ER stress regulates amyloid precursor protein processing through ubiquitin-dependent degradation.

Scientific Reports
Jung, Eun Sun ES; Hong, HyunSeok H; Kim, Chaeyoung C; Mook-Jung, Inhee I
Publication Date: 2015-03-05

Variant appearance in text: TGN: M146L
PubMed Link: 25740315
Variant Present in the following documents:
  • Main text
  • srep08805.pdf
View BVdb publication page



Traditional used Plants against Cognitive Decline and Alzheimer Disease.

Frontiers In Pharmacology
Eckert, Gunter Peter GP
Publication Date: 2010

Variant appearance in text: TG: M146L
PubMed Link: 21833177
Variant Present in the following documents:
  • Main text
  • fphar-01-00138.pdf
View BVdb publication page



Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease.

Journal Of Neuroinflammation
Paris, Daniel D; Ganey, Nowell J NJ; Laporte, Vincent V; Patel, Nikunj S NS; Beaulieu-Abdelahad, David D; Bachmeier, Corbin C; March, Amelia A; Ait-Ghezala, Ghania G; Mullan, Michael J MJ
Publication Date: 2010-03-08

Variant appearance in text: TG: M146L
PubMed Link: 20211007
Variant Present in the following documents:
  • 1742-2094-7-17.pdf
View BVdb publication page



Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease--a review.

Journal Of Lipid Research
Ariga, Toshio T; McDonald, Michael P MP; Yu, Robert K RK
Publication Date: 2008-06

Variant appearance in text: TG: M146L
PubMed Link: 18334715
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mostly separate distributions of CLAC- versus Abeta40- or thioflavin S-reactivities in senile plaques reveal two distinct subpopulations of beta-amyloid deposits.

The American Journal Of Pathology
Kowa, Hisatomo H; Sakakura, Tomoko T; Matsuura, Yusuke Y; Wakabayashi, Tomoko T; Mann, David M A DM; Duff, Karen K; Tsuji, Shoji S; Hashimoto, Tadafumi T; Iwatsubo, Takeshi T
Publication Date: 2004-07

Variant appearance in text: TG: M146L
PubMed Link: 15215182
Variant Present in the following documents:
  • Main text
View BVdb publication page