Publications:

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NAT2 global landscape: Genetic diversity and acetylation statuses from a systematic review.

Plos One

Gutiérrez-Virgen, Jorge E JE; Piña-Pozas, Maricela M; Hernández-Tobías, Esther A EA; Taja-Chayeb, Lucia L; López-González, Ma de Lourdes ML; Meraz-Ríos, Marco A MA; Gómez, Rocío R

Publication Date: 2023

Variant appearance in text: rs1801279

PubMed Link: 37023111

Variant Present in the following documents:

• Main text
• pone.0283726.pdf
• pone.0283726.s016.xlsx, sheet 1
• pone.0283726.s015.xlsx, sheet 1

View BVdb publication page

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Identification of PCSK9-like human gene knockouts using metabolomics, proteomics, and whole-genome sequencing in a consanguineous population.

Cell Genomics

Belkadi, Aziz A; Thareja, Gaurav G; Abbaszadeh, Fatemeh F; Badii, Ramin R; Fauman, Eric E; Albagha, Omar M E OME; , ; Suhre, Karsten K

Publication Date: 2023-01-11

Variant appearance in text: NAT2: Arg64Gln; rs1801279

PubMed Link: 36777185

Variant Present in the following documents:

• mmc6.xlsx, sheet 2

View BVdb publication page

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Association between cigarette smoking and ovarian reserve among women seeking fertility care.

Plos One

Oladipupo, Islamiat I; Ali, T'shura T; Hein, David W DW; Pagidas, Kelly K; Bohler, Henry H; Doll, Mark A MA; Mann, Merry Lynn ML; Gentry, Adrienne A; Chiang, Jasmine L JL; Pierson, Rebecca C RC; Torres, Sashia S; Reece, Emily E; Taylor, Kira C KC

Publication Date: 2022

Variant appearance in text: rs1801279

PubMed Link: 36512605

Variant Present in the following documents:

• Main text
• pone.0278998.pdf

View BVdb publication page

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Quantitative Analysis of Isoniazid and Its Four Primary Metabolites in Plasma of Tuberculosis Patients Using LC-MS/MS.

Molecules (Basel, Switzerland)

Ky Anh, Nguyen N; My Tung, Pham P; Kim, Min Jung MJ; Phuoc Long, Nguyen N; Cho, Yong-Soon YS; Kim, Dong-Hyun DH; Shin, Jae-Gook JG

Publication Date: 2022-12-06

Variant appearance in text: NAT2: 191G>A

PubMed Link: 36500699

Variant Present in the following documents:

• Main text
• molecules-27-08607.pdf

View BVdb publication page

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Global estimates and determinants of antituberculosis drug pharmacokinetics in children and adolescents: a systematic review and individual patient data meta-analysis.

The European Respiratory Journal

Gafar, Fajri F; Wasmann, Roeland E RE; McIlleron, Helen M HM; Aarnoutse, Rob E RE; Schaaf, H Simon HS; Marais, Ben J BJ; Agarwal, Dipti D; Antwi, Sampson S; Bang, Nguyen D ND; Bekker, Adrie A; Bell, David J DJ; Chabala, Chishala C; Choo, Louise L; Davies, Geraint R GR; Day, Jeremy N JN; Dayal, Rajeshwar R; Denti, Paolo P; Donald, Peter R PR; Engidawork, Ephrem E; Garcia-Prats, Anthony J AJ; Gibb, Diana D; Graham, Stephen M SM; Hesseling, Anneke C AC; Heysell, Scott K SK; Idris, Misgana I MI; Kabra, Sushil K SK; Kinikar, Aarti A; Hemanth Kumar, Agibothu K AK; Kwara, Awewura A; Lodha, Rakesh R; Magis-Escurra, Cecile C; Martinez, Nilza N; Mathew, Binu S BS; Mave, Vidya V; Mduma, Estomih E; Mlotha-Mitole, Rachel R; Mpagama, Stellah G SG; Mukherjee, Aparna A; Nataprawira, Heda M HM; Peloquin, Charles A CA; Pouplin, Thomas T; Ramachandran, Geetha G; Ranjalkar, Jaya J; Roy, Vandana V; Ruslami, Rovina R; Shah, Ira I; Singh, Yatish Y; Sturkenboom, Marieke G G MGG; Svensson, Elin M EM; Swaminathan, Soumya S; Thatte, Urmila U; Thee, Stephanie S; Thomas, Tania A TA; Tikiso, Tjokosela T; Touw, Daan J DJ; Turkova, Anna A; Velpandian, Thirumurthy T; Verhagen, Lilly M LM; Winckler, Jana L JL; Yang, Hongmei H; Yunivita, Vycke V; Taxis, Katja K; Stevens, Jasper J; Alffenaar, Jan-Willem C JC; ,

Publication Date: 2022-11-03

Variant appearance in text: rs1801279

PubMed Link: 36328357

Variant Present in the following documents:

• ERJ-01596-2022.Supplement.pdf

View BVdb publication page

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Genetic susceptibility of bladder cancer in the Lebanese population.

Bmc Medical Genomics

Kourie, Hampig Raphael HR; Succar, Bahaa B; Chouery, Eliane E; Mehawej, Cybel C; Ahmadieh, Nizar N; Zouein, Joseph J; Mardirossian, Avedis A; Jalkh, Nadine N; Sleilaty, Ghassan G; Kattan, Joseph J; Nemr, Elie E

Publication Date: 2022-10-17

Variant appearance in text: NAT2: 191G>A; Arg64Gln; rs1801279

PubMed Link: 36253817

Variant Present in the following documents:

• 12920_2022_1372_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Influence of N-acetyltransferase 2 (NAT2) genotype/single nucleotide polymorphisms on clearance of isoniazid in tuberculosis patients: a systematic review of population pharmacokinetic models.

European Journal Of Clinical Pharmacology

Thomas, Levin L; Raju, Arun Prasath AP; Chaithra, ; M, Sonal Sekhar SS; Varma, Muralidhar M; Saravu, Kavitha K; Banerjee, Mithu M; Sv, Chidananda Sanju CS; Mallayasamy, Surulivelrajan S; Rao, Mahadev M

Publication Date: 2022-10

Variant appearance in text: NAT2: 191G>A; rs1801279

PubMed Link: 35852584

Variant Present in the following documents:

• Main text
• 228_2022_Article_3362.pdf

View BVdb publication page

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Homozygotes NAT2*5B slow acetylators are highly associated with hepatotoxicity induced by anti-tuberculosis drugs.

Memorias Do Instituto Oswaldo Cruz

El-Jaick, Kenia Balbi KB; Ribeiro-Alves, Marcelo M; Soares, Marcos Vinícius Guimarães MVG; Araujo, Gabriela Eduardo França de GEF; Pereira, Gabriel Rodrigues Coutinho GRC; Rolla, Valeria Cavalcanti VC; Mesquita, Joelma Freire De JF; De Castro, Liane L

Publication Date: 2022

Variant appearance in text: NAT2: 191G>A; rs1801279

PubMed Link: 35588539

Variant Present in the following documents:

• Main text
• 1678-8060-mioc-117-e210328.pdf

View BVdb publication page

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Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.

Nature Neuroscience

Baxi, Emily G EG; Thompson, Terri T; Li, Jonathan J; Kaye, Julia A JA; Lim, Ryan G RG; Wu, Jie J; Ramamoorthy, Divya D; Lima, Leandro L; Vaibhav, Vineet V; Matlock, Andrea A; Frank, Aaron A; Coyne, Alyssa N AN; Landin, Barry B; Ornelas, Loren L; Mosmiller, Elizabeth E; Thrower, Sara S; Farr, S Michelle SM; Panther, Lindsey L; Gomez, Emilda E; Galvez, Erick E; Perez, Daniel D; Meepe, Imara I; Lei, Susan S; Mandefro, Berhan B; Trost, Hannah H; Pinedo, Louis L; Banuelos, Maria G MG; Liu, Chunyan C; Moran, Ruby R; Garcia, Veronica V; Workman, Michael M; Ho, Richie R; Wyman, Stacia S; Roggenbuck, Jennifer J; Harms, Matthew B MB; Stocksdale, Jennifer J; Miramontes, Ricardo R; Wang, Keona K; Venkatraman, Vidya V; Holewenski, Ronald R; Sundararaman, Niveda N; Pandey, Rakhi R; Manalo, Danica-Mae DM; Donde, Aneesh A; Huynh, Nhan N; Adam, Miriam M; Wassie, Brook T BT; Vertudes, Edward E; Amirani, Naufa N; Raja, Krishna K; Thomas, Reuben R; Hayes, Lindsey L; Lenail, Alex A; Cerezo, Aianna A; Luppino, Sarah S; Farrar, Alanna A; Pothier, Lindsay L; Prina, Carolyn C; Morgan, Todd T; Jamil, Arish A; Heintzman, Sarah S; Jockel-Balsarotti, Jennifer J; Karanja, Elizabeth E; Markway, Jesse J; McCallum, Molly M; Joslin, Ben B; Alibazoglu, Deniz D; Kolb, Stephen S; Ajroud-Driss, Senda S; Baloh, Robert R; Heitzman, Daragh D; Miller, Tim T; Glass, Jonathan D JD; Patel-Murray, Natasha Leanna NL; Yu, Hong H; Sinani, Ervin E; Vigneswaran, Prasha P; Sherman, Alexander V AV; Ahmad, Omar O; Roy, Promit P; Beavers, Jay C JC; Zeiler, Steven S; Krakauer, John W JW; Agurto, Carla C; Cecchi, Guillermo G; Bellard, Mary M; Raghav, Yogindra Y; Sachs, Karen K; Ehrenberger, Tobias T; Bruce, Elizabeth E; Cudkowicz, Merit E ME; Maragakis, Nicholas N; Norel, Raquel R; Van Eyk, Jennifer E JE; Finkbeiner, Steven S; Berry, James J; Sareen, Dhruv D; Thompson, Leslie M LM; Fraenkel, Ernest E; Svendsen, Clive N CN; Rothstein, Jeffrey D JD

Publication Date: 2022-02

Variant appearance in text: NAT2: R64Q; rs1801279

PubMed Link: 35115730

Variant Present in the following documents:

• 41593_2021_1006_MOESM4_ESM.xlsx, sheet 9

View BVdb publication page

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Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Translational And Clinical Pharmacology

Kim, Byungwook B; Yoon, Deok Yong DY; Lee, SeungHwan S; Jang, In-Jin IJ; Yu, Kyung-Sang KS; Cho, Joo-Youn JY; Oh, Jaeseong J

Publication Date: 2021-09

Variant appearance in text: NAT2: 191G>A; R64Q; rs1801279

PubMed Link: 34621706

Variant Present in the following documents:

• tcp-29-135-s001.xls, sheet 1

View BVdb publication page

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Population Genetic Difference of Pharmacogenomic VIP Variants in the Tibetan Population.

Pharmacogenomics And Personalized Medicine

He, Chunjuan C; Peng, Linna L; Xing, Shishi S; Li, Dandan D; Wang, Li L; Jin, Tianbo T

Publication Date: 2021

Variant appearance in text: rs1801279

PubMed Link: 34429635

Variant Present in the following documents:

• Main text
• pgpm-14-1027.pdf

View BVdb publication page

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Current concepts and molecular mechanisms in pharmacogenetics of essential hypertension.

Indian Journal Of Pharmacology

Rahman, Farhana F; Muthaiah, Nagasundaram N; Kumaramanickavel, Govindasamy G

Publication Date: 2021

Variant appearance in text: NAT2: Arg64Gln; rs1801279

PubMed Link: 34414909

Variant Present in the following documents:

• Main text

View BVdb publication page

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Acetylator Status Among Newly Diagnosed and Recurrent Tuberculosis Patients from Kupang, Eastern Part of Indonesia.

Pharmacogenomics And Personalized Medicine

Sahiratmadja, Edhyana E; Rini, Ika Agus IA; Penggoam, Simeon S; Charles, Afandi A; Maskoen, Ani Melani AM; Parwati, Ida I

Publication Date: 2021

Variant appearance in text: NAT2: R64Q; rs1801279

PubMed Link: 34188520

Variant Present in the following documents:

• Main text
• pgpm-14-737.pdf

View BVdb publication page

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Functional Characterization of the Effects of N-acetyltransferase 2 Alleles on N-acetylation of Eight Drugs and Worldwide Distribution of Substrate-Specific Diversity.

Frontiers In Genetics

Fukunaga, Koya K; Kato, Ken K; Okusaka, Takuji T; Saito, Takeo T; Ikeda, Masashi M; Yoshida, Teruhiko T; Zembutsu, Hitoshi H; Iwata, Nakao N; Mushiroda, Taisei T

Publication Date: 2021

Variant appearance in text: NAT2: 191G>A; rs1801279

PubMed Link: 33815485

Variant Present in the following documents:

• Main text
• fgene-12-652704.pdf

View BVdb publication page

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Genetic Diversity of Drug-Related Genes in Native Americans of the Brazilian Amazon.

Pharmacogenomics And Personalized Medicine

Fernandes, Marianne Rodrigues MR; Rodrigues, Juliana Carla Gomes JCG; Maroñas, Olalla O; Latorre-Pellicer, Ana A; Cruz, Raquel R; Guerreiro, João Farias JF; Burbano, Rommel Mario Rodriguez RMR; de Assumpção, Paulo Pimentel PP; Ribeiro-Dos-Santos, Andrea A; Dos Santos, Sidney Emanuel Batista SEB; Carracedo, Angel A; Dos Santos, Ney Pereira Carneiro NPC

Publication Date: 2021

Variant appearance in text: rs1801279

PubMed Link: 33519226

Variant Present in the following documents:

• Main text
• pgpm-14-117.pdf

View BVdb publication page

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Defining eligible patients for allele-selective chemotherapies targeting NAT2 in colorectal cancer.

Scientific Reports

Rendo, Veronica V; Kundu, Snehangshu S; Rameika, Natallia N; Ljungström, Viktor V; Svensson, Richard R; Palin, Kimmo K; Aaltonen, Lauri L; Stoimenov, Ivaylo I; Sjöblom, Tobias T

Publication Date: 2020-12-31

Variant appearance in text: rs1801279

PubMed Link: 33384440

Variant Present in the following documents:

• Main text
• 41598_2020_80288_MOESM2_ESM.xlsx, sheet 1
• 41598_2020_Article_80288.pdf

View BVdb publication page

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Arylamine N-acetyltransferase acetylation polymorphisms: paradigm for pharmacogenomic-guided therapy- a focused review.

Expert Opinion On Drug Metabolism & Toxicology

Hein, David W DW; Millner, Lori M LM

Publication Date: 2021-01

Variant appearance in text: NAT2: R64Q; rs1801279

PubMed Link: 33094670

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genotype-Environment Interaction Analysis of NQO1, CYP2E1, and NAT2 Polymorphisms and the Risk of Childhood Acute Lymphoblastic Leukemia: A Report From the Mexican Interinstitutional Group for the Identification of the Causes of Childhood Leukemia.

Frontiers In Oncology

Medina-Sanson, Aurora A; Núñez-Enríquez, Juan Carlos JC; Hurtado-Cordova, Eduardo E; Pérez-Saldivar, María Luisa ML; Martínez-García, Anayeli A; Jiménez-Hernández, Elva E; Fernández-López, Juan Carlos JC; Martín-Trejo, Jorge Alfonso JA; Pérez-Lorenzana, Héctor H; Flores-Lujano, Janet J; Amador-Sánchez, Raquel R; Mora-Ríos, Felix Gustavo FG; Peñaloza-González, José Gabriel JG; Duarte-Rodríguez, David Aldebarán DA; Torres-Nava, José Refugio JR; Flores-Bautista, Juan Eduardo JE; Espinosa-Elizondo, Rosa Martha RM; Román-Zepeda, Pedro Francisco PF; Flores-Villegas, Luz Victoria LV; González-Ulivarri, Juana Esther JE; Martínez-Silva, Sofía Irene SI; Espinoza-Anrubio, Gilberto G; Almeida-Hernández, Carolina C; Ramírez-Colorado, Rosario R; Hernández-Mora, Luis L; García-López, Luis Ramiro LR; Cruz-Ojeda, Gabriela Adriana GA; Godoy-Esquivel, Arturo Emilio AE; Contreras-Hernández, Iris I; Medina-Hernández, Abraham A; López-Caballero, María Guadalupe MG; Hernández-Pineda, Norma Angélica NA; Granados-Kraulles, Jorge J; Rodríguez-Vázquez, María Adriana MA; Torres-Valle, Delfino D; Cortés-Reyes, Carlos C; Medrano-López, Francisco F; Pérez-Gómez, Jessica Arleet JA; Martínez-Ríos, Annel A; Aguilar-De Los Santos, Antonio A; Serafin-Díaz, Berenice B; Bekker-Méndez, Vilma Carolina VC; Mata-Rocha, Minerva M; Morales-Castillo, Blanca Angélica BA; Sepúlveda-Robles, Omar Alejandro OA; Ramírez-Bello, Julián J; Rosas-Vargas, Haydeé H; Hidalgo-Miranda, Alfredo A; Mejía-Aranguré, Juan Manuel JM; Jiménez-Morales, Silvia S

Publication Date: 2020

Variant appearance in text: rs1801279

PubMed Link: 33072605

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genotype-Guided Hydralazine Therapy.

American Journal Of Nephrology

Collins, Kimberly S KS; Raviele, Anthony L J ALJ; Elchynski, Amanda L AL; Woodcock, Alexander M AM; Zhao, Yang Y; Cooper-DeHoff, Rhonda M RM; Eadon, Michael T MT

Publication Date: 2020

Variant appearance in text: rs1801279

PubMed Link: 32927458

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmacokinetics and Drug-Drug Interactions of Isoniazid and Efavirenz in Pregnant Women Living With HIV in High TB Incidence Settings: Importance of Genotyping.

Clinical Pharmacology And Therapeutics

Gausi, Kamunkhwala K; Wiesner, Lubbe L; Norman, Jennifer J; Wallis, Carole L CL; Onyango-Makumbi, Carolyne C; Chipato, Tsungai T; Haas, David W DW; Browning, Renee R; Chakhtoura, Nahida N; Montepiedra, Grace G; Aaron, Lisa L; McCarthy, Katie K; Bradford, Sarah S; Vhembo, Tichaona T; Stranix-Chibanda, Lynda L; Masheto, Gaerolwe R GR; Violari, Avy A; Mmbaga, Blandina T BT; Aurpibul, Linda L; Bhosale, Ramesh R; Nevrekhar, Neetal N; Rouzier, Vanessa V; Kabugho, Enid E; Mutambanengwe, Mercy M; Chanaiwa, Vongai V; Nyati, Mandisa M; Mhembere, Tsungai T; Tongprasert, Fuanglada F; Hesseling, Anneke A; Shin, Katherine K; Zimmer, Bonnie B; Costello, Diane D; Jean-Philippe, Patrick P; Sterling, Timothy R TR; Theron, Gerhard G; Weinberg, Adriana A; Gupta, Amita A; Denti, Paolo P; ,

Publication Date: 2021-04

Variant appearance in text: rs1801279

PubMed Link: 32909316

Variant Present in the following documents:

• Main text

View BVdb publication page

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Effects of Pregnancy and Isoniazid Preventive Therapy on Mycobacterium tuberculosis Interferon Gamma Response Assays in Women With HIV.

Clinical Infectious Diseases : An Official Publication Of The Infectious Diseases Society Of America

Weinberg, Adriana A; Aaron, Lisa L; Montepiedra, Grace G; Sterling, Timothy R TR; Browning, Renee R; Mmbaga, Blandina B; Vhembo, Tichaona T; Naik, Shilpa S; Kabugho, Enid E; Masheto, Gaerolwe G; Pahwa, Savita S; Mathad, Jyoti S JS; LaCourse, Sylvia M SM; McCarthy, Katie K; Bradford, Sarah S; Theron, Gerhard G; Costello, Diane D; Zimmer, Bonnie B; Pierre, Marie F MF; Gausi, Kamunkhwala K; Denti, Paolo P; Haas, David W DW; Gupta, Amita A; ,

Publication Date: 2021-11-02

Variant appearance in text: rs1801279

PubMed Link: 32720695

Variant Present in the following documents:

• Main text

View BVdb publication page

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Study on Genotyping Polymorphism and Sequencing of N-Acetyltransferase 2 (NAT2) among Al-Ahsa Population.

Biomed Research International

Zahra, Mohammad Abu MA; Kandeel, Mahmoud M; Aldossary, Sara A SA; Al-Taher, Abdulla A

Publication Date: 2020

Variant appearance in text: NAT2: Arg64Gln; rs1801279

PubMed Link: 32626768

Variant Present in the following documents:

• Main text

View BVdb publication page

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Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing.

Clinical Pharmacokinetics

Yin, Anyue A; Ettaieb, Madeleine H T MHT; Swen, Jesse J JJ; van Deun, Liselotte L; Kerkhofs, Thomas M A TMA; van der Straaten, Robert J H M RJHM; Corssmit, Eleonora P M EPM; Gelderblom, Hans H; Kerstens, Michiel N MN; Feelders, Richard A RA; Eekhoff, Marelise M; Timmers, Henri J L M HJLM; D'Avolio, Antonio A; Cusato, Jessica J; Guchelaar, Henk-Jan HJ; Haak, Harm R HR; Moes, Dirk Jan A R DJAR

Publication Date: 2021-01

Variant appearance in text: NAT2: 191G>A; R64Q; rs1801279

PubMed Link: 32607875

Variant Present in the following documents:

• 40262_2020_913_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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A Scoping Review of Interactions between Omega-3 Long-Chain Polyunsaturated Fatty Acids and Genetic Variation in Relation to Cancer Risk.

Nutrients

Yurko-Mauro, Karin K; Van Elswyk, Mary M; Teo, Lynn L

Publication Date: 2020-06-02

Variant appearance in text: NAT2: Arg64Gln; rs1801279

PubMed Link: 32498320

Variant Present in the following documents:

• Main text
• nutrients-12-01647.pdf

View BVdb publication page

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Haplotype-specific PCR for NAT2 diplotyping.

Human Genome Variation

Wichukchinda, Nuanjun N; Pakdee, Jirapa J; Kunhapan, Punna P; Imunchot, Wimala W; Toyo-Oka, Licht L; Tokunaga, Katsushi K; Mahasirimongkol, Surakameth S

Publication Date: 2020

Variant appearance in text: NAT2: R64Q; rs1801279

PubMed Link: 32411379

Variant Present in the following documents:

• Main text

View BVdb publication page

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Implementation of a Renal Precision Medicine Program: Clinician Attitudes and Acceptance.

Life (Basel, Switzerland)

Spiech, Katherine M KM; Tripathy, Purnima R PR; Woodcock, Alex M AM; Sheth, Nehal A NA; Collins, Kimberly S KS; Kannegolla, Karthik K; Sinha, Arjun D AD; Sharfuddin, Asif A AA; Pratt, Victoria M VM; Khalid, Myda M; Hains, David S DS; Moe, Sharon M SM; Skaar, Todd C TC; Moorthi, Ranjani N RN; Eadon, Michael T MT

Publication Date: 2020-03-26

Variant appearance in text: rs1801279

PubMed Link: 32224869

Variant Present in the following documents:

• Main text
• life-10-00032.pdf

View BVdb publication page

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The association between NAT2 acetylator status and adverse drug reactions of sulfasalazine: a systematic review and meta-analysis.

Scientific Reports

Yee, Jeong J; Kim, So Min SM; Han, Ji Min JM; Lee, Nari N; Yoon, Ha Young HY; Gwak, Hye Sun HS

Publication Date: 2020-02-27

Variant appearance in text: rs1801279

PubMed Link: 32107440

Variant Present in the following documents:

• Main text
• 41598_2020_Article_60467.pdf

View BVdb publication page

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Population Pharmacokinetics of Isoniazid, Pyrazinamide, and Ethambutol in Pregnant South African Women with Tuberculosis and HIV.

Antimicrobial Agents And Chemotherapy

Abdelwahab, Mahmoud Tareq MT; Leisegang, Rory R; Dooley, Kelly E KE; Mathad, Jyoti S JS; Wiesner, Lubbe L; McIlleron, Helen H; Martinson, Neil N; Waja, Ziyaad Z; Letutu, Matebogo M; Chaisson, Richard E RE; Denti, Paolo P

Publication Date: 2020-02-21

Variant appearance in text: rs1801279

PubMed Link: 31844002

Variant Present in the following documents:

• Main text

View BVdb publication page

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Systematic Review of Genetic Factors in the Etiology of Esophageal Squamous Cell Carcinoma in African Populations.

Frontiers In Genetics

Simba, Hannah H; Kuivaniemi, Helena H; Lutje, Vittoria V; Tromp, Gerard G; Sewram, Vikash V

Publication Date: 2019

Variant appearance in text: rs1801279

PubMed Link: 31428123

Variant Present in the following documents:

• Main text

View BVdb publication page

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Mitochondrial DNA Variants in Patients with Liver Injury Due to Anti-Tuberculosis Drugs.

Journal Of Clinical Medicine

Lee, Li-Na LN; Huang, Chun-Ta CT; Hsu, Chia-Lin CL; Chang, Hsiu-Ching HC; Jan, I-Shiow IS; Liu, Jia-Luen JL; Sheu, Jin-Chuan JC; Wang, Jann-Tay JT; Liu, Wei-Lun WL; Wu, Huei-Shu HS; Chang, Ching-Nien CN; Wang, Jann-Yuan JY

Publication Date: 2019-08-13

Variant appearance in text: NAT2: R64Q

PubMed Link: 31412578

Variant Present in the following documents:

• jcm-08-01207-s001.pdf

View BVdb publication page

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Effect of N-Acetyltransferase 2 Genotype on the Pharmacokinetics of Hydralazine During Pregnancy.

Journal Of Clinical Pharmacology

Han, Lyrialle W LW; Ryu, Rachel J RJ; Cusumano, Michael M; Easterling, Thomas R TR; Phillips, Brian R BR; Risler, Linda J LJ; Shen, Danny D DD; Hebert, Mary F MF

Publication Date: 2019-12

Variant appearance in text: NAT2: 191G>A; rs1801279

PubMed Link: 31257615

Variant Present in the following documents:

• Main text

View BVdb publication page

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Isoniazid Concentration and NAT2 Genotype Predict Risk of Systemic Drug Reactions during 3HP for LTBI.

Journal Of Clinical Medicine

Lee, Meng-Rui MR; Huang, Hung-Ling HL; Lin, Shu-Wen SW; Cheng, Meng-Hsuan MH; Lin, Ya-Ting YT; Chang, So-Yi SY; Yan, Bo-Shiun BS; Kuo, Ching-Hua CH; Lu, Po-Liang PL; Wang, Jann-Yuan JY; Chong, Inn-Wen IW

Publication Date: 2019-06-06

Variant appearance in text: rs1801279

PubMed Link: 31174321

Variant Present in the following documents:

• jcm-08-00812-s001.pdf

View BVdb publication page

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N-acetyltransferase 2 enzyme genotype-phenotype discordances in both HIV-negative and HIV-positive Nigerians.

Pharmacogenetics And Genomics

Kotila, Olayinka A OA; Fawole, Olufunmilayo I OI; Olopade, Olufunmilayo I OI; Ayede, Adejumoke I AI; Falusi, Adeyinka G AG; Babalola, Chinedum P CP

Publication Date: 2019-07

Variant appearance in text: rs1801279

PubMed Link: 30882558

Variant Present in the following documents:

• Main text

View BVdb publication page

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NAT2 variants and toxicity related to anti-tuberculosis agents: a systematic review and meta-analysis.

The International Journal Of Tuberculosis And Lung Disease : The Official Journal Of The International Union Against Tuberculosis And Lung Disease

Richardson, M M; Kirkham, J J; Dwan, K K; Sloan, D J DJ; Davies, G G; Jorgensen, A L AL

Publication Date: 2019-03-01

Variant appearance in text: rs1801279

PubMed Link: 30871660

Variant Present in the following documents:

• Main text
• i1027-3719-23-3-293.pdf

View BVdb publication page

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Effects of genetic variability on rifampicin and isoniazid pharmacokinetics in South African patients with recurrent tuberculosis.

Pharmacogenomics

Naidoo, Anushka A; Chirehwa, Maxwell M; Ramsuran, Veron V; McIlleron, Helen H; Naidoo, Kogieleum K; Yende-Zuma, Nonhlanhla N; Singh, Ravesh R; Ncgapu, Sinaye S; Adamson, John J; Govender, Katya K; Denti, Paolo P; Padayatchi, Nesri N

Publication Date: 2019-03

Variant appearance in text: rs1801279

PubMed Link: 30767706

Variant Present in the following documents:

• Main text

View BVdb publication page

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Population genetic difference of pharmacogenomic VIP gene variants in the Lisu population from Yunnan Province.

Medicine

Zhang, Chan C; Jiang, Xiaochun X; Chen, Wanlu W; Li, Qi Q; Yun, Fubin F; Yang, Xin X; Dai, Run R; Cheng, Yujing Y

Publication Date: 2018-12

Variant appearance in text: NAT2: Arg64Gln; rs1801279

PubMed Link: 30593137

Variant Present in the following documents:

• medi-97-e13674.pdf

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Analytical validity of a genotyping assay for use with personalized antihypertensive and chronic kidney disease therapy.

Pharmacogenetics And Genomics

Collins, Kimberly S KS; Pratt, Victoria M VM; Stansberry, Wesley M WM; Medeiros, Elizabeth B EB; Kannegolla, Karthik K; Swart, Marelize M; Skaar, Todd C TC; Chapman, Arlene B AB; Decker, Brian S BS; Moorthi, Ranjani N RN; Eadon, Michael T MT

Publication Date: 2019-01

Variant appearance in text: NAT2: 191G>A; rs1801279

PubMed Link: 30489456

Variant Present in the following documents:

• Main text

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Non-alcoholic fatty liver disease: a narrative review of genetics.

Journal Of Biomedical Research

Danford, Christopher J CJ; Yao, Ze-Min ZM; Jiang, Z Gordon ZG

Publication Date: 2018-11-20

Variant appearance in text: rs1801279

PubMed Link: 30355853

Variant Present in the following documents:

• Main text
• jbr-32-6-389.pdf

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An optimized prediction framework to assess the functional impact of pharmacogenetic variants.

The Pharmacogenomics Journal

Zhou, Yitian Y; Mkrtchian, Souren S; Kumondai, Masaki M; Hiratsuka, Masahiro M; Lauschke, Volker M VM

Publication Date: 2019-04

Variant appearance in text: NAT2: R64Q; rs1801279

PubMed Link: 30206299

Variant Present in the following documents:

• 41397_2018_44_MOESM5_ESM.xlsx, sheet 1

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Evaluation of the Adequacy of WHO Revised Dosages of the First-Line Antituberculosis Drugs in Children with Tuberculosis Using Population Pharmacokinetic Modeling and Simulations.

Antimicrobial Agents And Chemotherapy

Horita, Yasuhiro Y; Alsultan, Abdullah A; Kwara, Awewura A; Antwi, Sampson S; Enimil, Antony A; Ortsin, Antoinette A; Dompreh, Albert A; Yang, Hongmei H; Wiesner, Lubbe L; Peloquin, Charles A CA

Publication Date: 2018-09

Variant appearance in text: rs1801279

PubMed Link: 29914960

Variant Present in the following documents:

• Main text

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Disease burden and the role of pharmacogenomics in African populations.

Global Health, Epidemiology And Genomics

Mpye, K L KL; Matimba, A A; Dzobo, K K; Chirikure, S S; Wonkam, A A; Dandara, C C

Publication Date: 2017

Variant appearance in text: NAT2: 191G>A

PubMed Link: 29868213

Variant Present in the following documents:

• Main text

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N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians.

European Journal Of Clinical Pharmacology

Aklillu, Eleni E; Carrillo, Juan Antonio JA; Makonnen, Eyasu E; Bertilsson, Leif L; Djordjevic, Natasa N

Publication Date: 2018-07

Variant appearance in text: rs1801279

PubMed Link: 29589062

Variant Present in the following documents:

• Main text

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Population genomic analysis of elongated skulls reveals extensive female-biased immigration in Early Medieval Bavaria.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Veeramah, Krishna R KR; Rott, Andreas A; Groß, Melanie M; van Dorp, Lucy L; López, Saioa S; Kirsanow, Karola K; Sell, Christian C; Blöcher, Jens J; Wegmann, Daniel D; Link, Vivian V; Hofmanová, Zuzana Z; Peters, Joris J; Trautmann, Bernd B; Gairhos, Anja A; Haberstroh, Jochen J; Päffgen, Bernd B; Hellenthal, Garrett G; Haas-Gebhard, Brigitte B; Harbeck, Michaela M; Burger, Joachim J

Publication Date: 2018-03-27

Variant appearance in text: rs1801279

PubMed Link: 29531040

Variant Present in the following documents:

• pnas.1719880115.sapp.pdf

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Population genomics of Mesolithic Scandinavia: Investigating early postglacial migration routes and high-latitude adaptation.

Plos Biology

Günther, Torsten T; Malmström, Helena H; Svensson, Emma M EM; Omrak, Ayça A; Sánchez-Quinto, Federico F; Kılınç, Gülşah M GM; Krzewińska, Maja M; Eriksson, Gunilla G; Fraser, Magdalena M; Edlund, Hanna H; Munters, Arielle R AR; Coutinho, Alexandra A; Simões, Luciana G LG; Vicente, Mário M; Sjölander, Anders A; Jansen Sellevold, Berit B; Jørgensen, Roger R; Claes, Peter P; Shriver, Mark D MD; Valdiosera, Cristina C; Netea, Mihai G MG; Apel, Jan J; Lidén, Kerstin K; Skar, Birgitte B; Storå, Jan J; Götherström, Anders A; Jakobsson, Mattias M

Publication Date: 2018-01

Variant appearance in text: rs1801279

PubMed Link: 29315301

Variant Present in the following documents:

• pbio.2003703.s001.xlsx, sheet 1

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Genetic variation in human drug-related genes.

Genome Medicine

Schärfe, Charlotta Pauline Irmgard CPI; Tremmel, Roman R; Schwab, Matthias M; Kohlbacher, Oliver O; Marks, Debora Susan DS

Publication Date: 2017-12-22

Variant appearance in text: rs1801279

PubMed Link: 29273096

Variant Present in the following documents:

• 13073_2017_502_MOESM2_ESM.xlsx, sheet 2

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Effect of Genetic Variation of NAT2 on Isoniazid and SLCO1B1 and CES2 on Rifampin Pharmacokinetics in Ghanaian Children with Tuberculosis.

Antimicrobial Agents And Chemotherapy

Dompreh, Albert A; Tang, Xiaoli X; Zhou, Jianlin J; Yang, Hongmei H; Topletz, Ariel A; Adu Ahwireng, Eugene E; Antwi, Sampson S; Enimil, Antony A; Langaee, Taimour T; Peloquin, Charles A CA; Court, Michael H MH; Kwara, Awewura A

Publication Date: 2018-03

Variant appearance in text: NAT2: Arg64Gln; rs1801279

PubMed Link: 29263072

Variant Present in the following documents:

• Main text

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Sequence analysis of the N-acetyltransferase 2 gene (NAT2) among Jordanian volunteers.

The Libyan Journal Of Medicine

Jarrar, Yazun Bashir YB; Balasmeh, Ayat Ahmed AA; Jarrar, Wassan W

Publication Date: 2018-12

Variant appearance in text: NAT2: Arg64Gln

PubMed Link: 29173142

Variant Present in the following documents:

• Main text
• zljm-13-1408381.pdf

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Association and clinical utility of NAT2 in the prediction of isoniazid-induced liver injury in Singaporean patients.

Plos One

Chan, Sze Ling SL; Chua, Angeline Poh Gek APG; Aminkeng, Folefac F; Chee, Cynthia Bin Eng CBE; Jin, Shengnan S; Loh, Marie M; Gan, Suay Hong SH; Wang, Yee Tang YT; Brunham, Liam R LR

Publication Date: 2017

Variant appearance in text: rs1801279

PubMed Link: 29036176

Variant Present in the following documents:

• Main text
• pone.0186200.pdf

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Exploring public genomics data for population pharmacogenomics.

Plos One

Lakiotaki, Kleanthi K; Kanterakis, Alexandros A; Kartsaki, Evgenia E; Katsila, Theodora T; Patrinos, George P GP; Potamias, George G

Publication Date: 2017

Variant appearance in text: rs1801279

PubMed Link: 28771511

Variant Present in the following documents:

• Main text
• pone.0182138.pdf

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Evaluation of the Adequacy of the 2010 Revised World Health Organization Recommended Dosages of the First-line Antituberculosis Drugs for Children: Adequacy of Revised Dosages of TB Drugs for Children.

The Pediatric Infectious Disease Journal

Yang, Hongmei H; Enimil, Anthony A; Gillani, Fizza S FS; Antwi, Sampson S; Dompreh, Albert A; Ortsin, Antoinette A; Adu Awhireng, Eugene E; Owusu, Maxwell M; Wiesner, Lubbe L; Peloquin, Charles A CA; Kwara, Awewura A

Publication Date: 2018-01

Variant appearance in text: rs1801279

PubMed Link: 28719501

Variant Present in the following documents:

• Main text

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Catalytic properties and heat stabilities of novel recombinant human N-acetyltransferase 2 allozymes support existence of genetic heterogeneity within the slow acetylator phenotype.

Archives Of Toxicology

Hein, David W DW; Doll, Mark A MA

Publication Date: 2017-08

Variant appearance in text: NAT2: R64Q

PubMed Link: 28523442

Variant Present in the following documents:

• Main text

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Genetic heterogeneity among slow acetylator N-acetyltransferase 2 phenotypes in cryopreserved human hepatocytes.

Archives Of Toxicology

Doll, Mark A MA; Hein, David W DW

Publication Date: 2017-07

Variant appearance in text: rs1801279

PubMed Link: 28516247

Variant Present in the following documents:

• Main text

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Logistic Bayesian LASSO for genetic association analysis of data from complex sampling designs.

Journal Of Human Genetics

Zhang, Yuan Y; Hofmann, Jonathan N JN; Purdue, Mark P MP; Lin, Shili S; Biswas, Swati S

Publication Date: 2017-09

Variant appearance in text: rs1801279

PubMed Link: 28424482

Variant Present in the following documents:

• Main text
• nihms862047.pdf

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Recommendations for Optimizing Tuberculosis Treatment: Therapeutic Drug Monitoring, Pharmacogenetics, and Nutritional Status Considerations.

Annals Of Laboratory Medicine

Choi, Rihwa R; Jeong, Byeong Ho BH; Koh, Won Jung WJ; Lee, Soo Youn SY

Publication Date: 2017-03

Variant appearance in text: NAT2: 191G>A; rs1801279

PubMed Link: 28028995

Variant Present in the following documents:

• Main text

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Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics

Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR

Publication Date: 2017-03

Variant appearance in text: rs1801279

PubMed Link: 27984508

Variant Present in the following documents:

• fpc-27-089-s005.xlsx, sheet 2
• fpc-27-089-s004.xlsx, sheet 2

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Optimization of Clonazepam Therapy Adjusted to Patient's CYP3A Status and NAT2 Genotype.

The International Journal Of Neuropsychopharmacology

Tóth, Katalin K; Csukly, Gábor G; Sirok, Dávid D; Belic, Ales A; Kiss, Ádám Á; Háfra, Edit E; Déri, Máté M; Menus, Ádám Á; Bitter, István I; Monostory, Katalin K

Publication Date: 2016-12

Variant appearance in text: rs1801279

PubMed Link: 27639091

Variant Present in the following documents:

• Main text

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