HR c.2535G>C ;(p.L845F)

Variant ID: 8-21978304-C-G

NM_005144.4(HR):c.2535G>C;(p.L845F)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


The Evolution of Therapies Targeting Bruton Tyrosine Kinase for the Treatment of Chronic Lymphocytic Leukaemia: Future Perspectives.

Cancers
Eyre, Toby A TA; Riches, John C JC
Publication Date: 2023-05-03

Variant appearance in text: HR: L845F
PubMed Link: 37174062
Variant Present in the following documents:
  • Main text
  • cancers-15-02596.pdf
View BVdb publication page



Small molecule inhibitors targeting the cancers.

Medcomm
Liu, Gui-Hong GH; Chen, Tao T; Zhang, Xin X; Ma, Xue-Lei XL; Shi, Hua-Shan HS
Publication Date: 2022-12

Variant appearance in text: HR: L845F
PubMed Link: 36254250
Variant Present in the following documents:
  • Main text
  • MCO2-3-e181.pdf
View BVdb publication page



Revolution of Chronic Lymphocytic Leukemia Therapy: the Chemo-Free Treatment Paradigm.

Current Oncology Reports
Scheffold, Annika A; Stilgenbauer, Stephan S
Publication Date: 2020-02-05

Variant appearance in text: HR: L845F
PubMed Link: 32025827
Variant Present in the following documents:
  • 11912_2020_Article_881.pdf
View BVdb publication page



Functional and clinical relevance of VLA-4 (CD49d/CD29) in ibrutinib-treated chronic lymphocytic leukemia.

The Journal Of Experimental Medicine
Tissino, Erika E; Benedetti, Dania D; Herman, Sarah E M SEM; Ten Hacken, Elisa E; Ahn, Inhye E IE; Chaffee, Kari G KG; Rossi, Francesca Maria FM; Dal Bo, Michele M; Bulian, Pietro P; Bomben, Riccardo R; Bayer, Elisabeth E; Härzschel, Andrea A; Gutjahr, Julia Christine JC; Postorino, Massimiliano M; Santinelli, Enrico E; Ayed, Ayed A; Zaja, Francesco F; Chiarenza, Annalisa A; Pozzato, Gabriele G; Chigaev, Alexandre A; Sklar, Larry A LA; Burger, Jan A JA; Ferrajoli, Alessandra A; Shanafelt, Tait D TD; Wiestner, Adrian A; Del Poeta, Giovanni G; Hartmann, Tanja Nicole TN; Gattei, Valter V; Zucchetto, Antonella A
Publication Date: 2018-02-05

Variant appearance in text: HR: L845F
PubMed Link: 29301866
Variant Present in the following documents:
  • Main text
  • JEM_20171288.pdf
View BVdb publication page



PI3K Signaling in Normal B Cells and Chronic Lymphocytic Leukemia (CLL).

Current Topics In Microbiology And Immunology
Okkenhaug, Klaus K; Burger, Jan A JA
Publication Date: 2016

Variant appearance in text: HR: L845F
PubMed Link: 26350103
Variant Present in the following documents:
  • 978-3-319-26133-1_Chapter_484.pdf
View BVdb publication page



Etiology of Ibrutinib Therapy Discontinuation and Outcomes in Patients With Chronic Lymphocytic Leukemia.

Jama Oncology
Maddocks, Kami J KJ; Ruppert, Amy S AS; Lozanski, Gerard G; Heerema, Nyla A NA; Zhao, Weiqiang W; Abruzzo, Lynne L; Lozanski, Arletta A; Davis, Melanie M; Gordon, Amber A; Smith, Lisa L LL; Mantel, Rose R; Jones, Jeffrey A JA; Flynn, Joseph M JM; Jaglowski, Samantha M SM; Andritsos, Leslie A LA; Awan, Farrukh F; Blum, Kristie A KA; Grever, Michael R MR; Johnson, Amy J AJ; Byrd, John C JC; Woyach, Jennifer A JA
Publication Date: 2015-04

Variant appearance in text: HR: L845F
PubMed Link: 26182309
Variant Present in the following documents:
  • Main text
View BVdb publication page