Publications:

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Rare Dysfunctional Complement Factor I Genetic Variants and Progression to Advanced Age-Related Macular Degeneration.

Ophthalmology Science

Seddon, Johanna M JM; Rosner, Bernard B; De, Dikha D; Huan, Tianxiao T; Java, Anuja A; Atkinson, John J

Publication Date: 2023-06

Variant appearance in text: HR: E318D

PubMed Link: 36909148

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• Main text
• main.pdf

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Genetic Susceptibility, Diet Quality, and Two-Step Progression in Drusen Size.

Investigative Ophthalmology & Visual Science

Merle, Bénédicte M J BMJ; Rosner, Bernard B; Seddon, Johanna M JM

Publication Date: 2020-05-11

Variant appearance in text: HR: E318D

PubMed Link: 32407518

Variant Present in the following documents:

• iovs-61-5-17.pdf

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Validated Prediction Models for Macular Degeneration Progression and Predictors of Visual Acuity Loss Identify High-Risk Individuals.

American Journal Of Ophthalmology

Seddon, Johanna M JM; Rosner, Bernard B

Publication Date: 2019-02

Variant appearance in text: HR: E318D

PubMed Link: 30389371

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• Main text

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Macular Degeneration Epidemiology: Nature-Nurture, Lifestyle Factors, Genetic Risk, and Gene-Environment Interactions - The Weisenfeld Award Lecture.

Investigative Ophthalmology & Visual Science

Seddon, Johanna M JM

Publication Date: 2017-12-01

Variant appearance in text: HR: E318D

PubMed Link: 29288272

Variant Present in the following documents:

• Main text
• i1552-5783-58-14-6513.pdf

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A Landscape of Pharmacogenomic Interactions in Cancer.

Cell

Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ

Publication Date: 2016-07-28

Variant appearance in text: HR: 954G>T; E318D

PubMed Link: 27397505

Variant Present in the following documents:

• mmc3.xlsx, sheet 3

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Dietary folate, B vitamins, genetic susceptibility and progression to advanced nonexudative age-related macular degeneration with geographic atrophy: a prospective cohort study.

The American Journal Of Clinical Nutrition

Merle, Bénédicte M J BM; Silver, Rachel E RE; Rosner, Bernard B; Seddon, Johanna M JM

Publication Date: 2016-04

Variant appearance in text: HR: E318D

PubMed Link: 26961928

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• Main text

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Adherence to a Mediterranean diet, genetic susceptibility, and progression to advanced macular degeneration: a prospective cohort study.

The American Journal Of Clinical Nutrition

Merle, Bénédicte M J BM; Silver, Rachel E RE; Rosner, Bernard B; Seddon, Johanna M JM

Publication Date: 2015-11

Variant appearance in text: HR: E318D

PubMed Link: 26490493

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• Main text

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Risk Prediction for Progression of Macular Degeneration: 10 Common and Rare Genetic Variants, Demographic, Environmental, and Macular Covariates.

Investigative Ophthalmology & Visual Science

Seddon, Johanna M JM; Silver, Rachel E RE; Kwong, Manlik M; Rosner, Bernard B

Publication Date: 2015-04

Variant appearance in text: HR: E318D

PubMed Link: 25655794

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Three new genetic loci (R1210C in CFH, variants in COL8A1 and RAD51B) are independently related to progression to advanced macular degeneration.

Plos One

Seddon, Johanna M JM; Reynolds, Robyn R; Yu, Yi Y; Rosner, Bernard B

Publication Date: 2014

Variant appearance in text: HR: E318D

PubMed Link: 24498017

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• Main text
• pone.0087047.pdf

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Dietary omega-3 fatty acids, other fat intake, genetic susceptibility, and progression to incident geographic atrophy.

Ophthalmology

Reynolds, Robyn R; Rosner, Bernard B; Seddon, Johanna M JM

Publication Date: 2013-05

Variant appearance in text: HR: E318D

PubMed Link: 23481534

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• Main text

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Validation of a prediction algorithm for progression to advanced macular degeneration subtypes.

Jama Ophthalmology

Seddon, Johanna M JM; Reynolds, Robyn R; Yu, Yi Y; Rosner, Bernard B

Publication Date: 2013-04

Variant appearance in text: HR: E318D

PubMed Link: 23411794

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• Main text

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Susceptibility to advanced age-related macular degeneration and alleles of complement factor H, complement factor B, complement component 2, complement component 3, and age-related maculopathy susceptibility 2 genes in a Mexican population.

Molecular Vision

Buentello-Volante, Beatriz B; Rodriguez-Ruiz, Gabriela G; Miranda-Duarte, Antonio A; Pompa-Mera, Ericka N EN; Graue-Wiechers, Federico F; Bekker-Méndez, Carolina C; Ayala-Ramirez, Raul R; Quezada, Carlos C; Rodríguez-Loaiza, Jose L JL; Zenteno, Juan C JC

Publication Date: 2012

Variant appearance in text: HR: E318D

PubMed Link: 23112567

Variant Present in the following documents:

• mv-v18-2518.pdf

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Dephosphorylation of the core clock protein KaiC in the cyanobacterial KaiABC circadian oscillator proceeds via an ATP synthase mechanism.

Biochemistry

Egli, Martin M; Mori, Tetsuya T; Pattanayek, Rekha R; Xu, Yao Y; Qin, Ximing X; Johnson, Carl H CH

Publication Date: 2012-02-28

Variant appearance in text: HR: E318D

PubMed Link: 22304631

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• Main text

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Prospective assessment of genetic effects on progression to different stages of age-related macular degeneration using multistate Markov models.

Investigative Ophthalmology & Visual Science

Yu, Yi Y; Reynolds, Robyn R; Rosner, Bernard B; Daly, Mark J MJ; Seddon, Johanna M JM

Publication Date: 2012-03

Variant appearance in text: HR: E318D

PubMed Link: 22247473

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Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors.

Ophthalmology

Seddon, Johanna M JM; Reynolds, Robyn R; Yu, Yi Y; Daly, Mark J MJ; Rosner, Bernard B

Publication Date: 2011-11

Variant appearance in text: HR: E318D

PubMed Link: 21959373

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Structures of KaiC circadian clock mutant proteins: a new phosphorylation site at T426 and mechanisms of kinase, ATPase and phosphatase.

Plos One

Pattanayek, Rekha R; Mori, Tetsuya T; Xu, Yao Y; Pattanayek, Sabuj S; Johnson, Carl H CH; Egli, Martin M

Publication Date: 2009-11-26

Variant appearance in text: HR: E318D

PubMed Link: 19956664

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• Main text
• pone.0007529.pdf

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