HR c.209A>G ;(p.K70R)

Variant ID: 8-21986475-T-C

NM_005144.4(HR):c.209A>G;(p.K70R)

This variant was identified in 29 publications

View GRCh38 version.




Publications:


Improving ethanol tolerance of ethyl carbamate hydrolase by diphasic high pressure molecular dynamic simulations.

Amb Express
Zan, Qijia Q; Long, Mengfei M; Zheng, Nan N; Zhang, Zehua Z; Zhou, Huimin H; Xu, Xinjie X; Osire, Tolbert T; Xia, Xiaole X
Publication Date: 2023-03-15

Variant appearance in text: HR: K70R
PubMed Link: 36920541
Variant Present in the following documents:
  • 13568_2023_Article_1538.pdf
View BVdb publication page



Magnitude and predictors of HIV-Drug resistance in Africa: A protocol for systematic review and meta-analysis.

Plos One
Melku, Mulugeta M; Gesesew, Hailay Abrha HA; Ward, Paul R PR
Publication Date: 2022

Variant appearance in text: HR: K70R
PubMed Link: 35442975
Variant Present in the following documents:
  • Main text
  • pone.0267159.pdf
View BVdb publication page



Highlights from the virtual conference on retroviruses and opportunistic infections (CROI) 2021: SARS-CoV-2 pathogenesis, new data about antiretroviral treatments, HIV-associated comorbidities, pediatrics and pregnancy.

Journal Of Virus Eradication
Psomas, Christina K CK; Waters, Laura J LJ; Barber, Tristan T
Publication Date: 2021-06

Variant appearance in text: HR: K70R
PubMed Link: 34249372
Variant Present in the following documents:
  • Main text
View BVdb publication page



Survival among antiretroviral-experienced HIV-2 patients experiencing virologic failure with drug resistance mutations in Cote d'Ivoire West Africa.

Plos One
Tchounga, Boris K BK; Charpentier, Charlotte C; Coffie, Patrick A PA; Dabis, François F; Descamps, Diane D; Eholie, Serge P SP; Ekouevi, Didier K DK
Publication Date: 2020

Variant appearance in text: HR: K70R
PubMed Link: 32756581
Variant Present in the following documents:
  • Main text
  • pone.0236642.pdf
View BVdb publication page



Minority and majority pretreatment HIV-1 drug resistance associated with failure of first-line nonnucleoside reverse-transcriptase inhibitor antiretroviral therapy in Kenyan women.

Aids (London, England)
Milne, Ross S RS; Silverman, Rachel A RA; Beck, Ingrid A IA; Mckernan-Mullin, Jennifer J; Deng, Wenjie W; Sibley, Thomas R TR; Dross, Sandra S; Kiarie, James N JN; Sakr, Samah R SR; Coombs, Robert W RW; Chung, Michael H MH; Frenkel, Lisa M LM
Publication Date: 2019-05-01

Variant appearance in text: HR: K70R
PubMed Link: 30946148
Variant Present in the following documents:
  • Main text
View BVdb publication page



Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.

Cell Death & Disease
Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D
Publication Date: 2019-02-27

Variant appearance in text: HR: 209A>G; Lys70Arg
PubMed Link: 30814510
Variant Present in the following documents:
  • 41419_2019_1453_MOESM27_ESM.xlsx, sheet 3
View BVdb publication page



Virological outcomes of boosted protease inhibitor-based first-line ART in subjects harbouring thymidine analogue-associated mutations as the sole form of transmitted drug resistance.

The Journal Of Antimicrobial Chemotherapy
Geretti, Anna Maria AM; White, Ellen E; Orkin, Chloe C; Tostevin, Anna A; Tilston, Peter P; Chadwick, David D; Leen, Clifford C; Sabin, Caroline C; Dunn, David T DT; ,
Publication Date: 2019-03-01

Variant appearance in text: HR: K70R
PubMed Link: 30544247
Variant Present in the following documents:
  • Main text
  • dky468.pdf
View BVdb publication page



Risk factors and outcomes for the Q151M and T69 insertion HIV-1 resistance mutations in historic UK data.

Aids Research And Therapy
Stirrup, Oliver T OT; Dunn, David T DT; Tostevin, Anna A; Sabin, Caroline A CA; Pozniak, Anton A; Asboe, David D; Cox, Alison A; Orkin, Chloe C; Martin, Fabiola F; Cane, Patricia P; , ; ,
Publication Date: 2018-04-16

Variant appearance in text: HR: K70R
PubMed Link: 29661246
Variant Present in the following documents:
  • Main text
  • 12981_2018_Article_198.pdf
View BVdb publication page



The Xanthomonas euvesicatoria type III effector XopAU is an active protein kinase that manipulates plant MAP kinase signaling.

Plos Pathogens
Teper, Doron D; Girija, Anil Madhusoodana AM; Bosis, Eran E; Popov, Georgy G; Savidor, Alon A; Sessa, Guido G
Publication Date: 2018-01

Variant appearance in text: HR: K70R
PubMed Link: 29377937
Variant Present in the following documents:
  • Main text
View BVdb publication page



HIV-1 genetic diversity and antiretroviral drug resistance among individuals from Roraima state, northern Brazil.

Plos One
Corado, André de Lima Guerra AL; Bello, Gonzalo G; Leão, Renato Augusto Carvalho RA; Granja, Fabiana F; Naveca, Felipe Gomes FG
Publication Date: 2017

Variant appearance in text: HR: K70R
PubMed Link: 28301548
Variant Present in the following documents:
  • pone.0173894.pdf
View BVdb publication page



Treatment Outcomes and Resistance Patterns of Children and Adolescents on Second-Line Antiretroviral Therapy in Asia.

Journal Of Acquired Immune Deficiency Syndromes (1999)
Prasitsuebsai, Wasana W; Teeraananchai, Sirinya S; Singtoroj, Thida T; Truong, Khanh Huu KH; Ananworanich, Jintanat J; Do, Viet Chau VC; Nguyen, Lam Van LV; Kosalaraksa, Pope P; Kurniati, Nia N; Sudjaritruk, Tavitiya T; Chokephaibulkit, Kulkanya K; Kerr, Stephen J SJ; Sohn, Annette H AH
Publication Date: 2016-08-01

Variant appearance in text: HR: K70R
PubMed Link: 27355415
Variant Present in the following documents:
  • Main text
View BVdb publication page



Outcome of patients on second line antiretroviral therapy under programmatic condition in India.

Bmc Infectious Diseases
Chakravarty, Jaya J; Sundar, Shyam S; Chourasia, Ankita A; Singh, Pallav Narayan PN; Kurle, Swarali S; Tripathy, Srikanth P SP; Chaturbhuj, Devidas N DN; Rai, Madhukar M; Agarwal, Amit Kumar AK; Mishra, Rabindra Nath RN; Paranjape, Ramesh S RS
Publication Date: 2015-11-14

Variant appearance in text: HR: K70R
PubMed Link: 26572102
Variant Present in the following documents:
  • Main text
  • 12879_2015_Article_1270.pdf
View BVdb publication page



Effectiveness of a Treatment Switch to Nevirapine plus Tenofovir and Emtricitabine (or Lamivudine) in Adults with HIV-1 Suppressed Viremia.

Plos One
Llibre, Josep M JM; Bravo, Isabel I; Ornelas, Arelly A; Santos, José R JR; Puig, Jordi J; Martin-Iguacel, Raquel R; Paredes, Roger R; Clotet, Bonaventura B
Publication Date: 2015

Variant appearance in text: HR: K70R
PubMed Link: 26107265
Variant Present in the following documents:
  • Main text
View BVdb publication page



High prevalence of the K65R mutation in HIV-1 subtype C infected patients failing tenofovir-based first-line regimens in South Africa.

Plos One
Skhosana, Lindiwe L; Steegen, Kim K; Bronze, Michelle M; Lukhwareni, Azwidowi A; Letsoalo, Esrom E; Papathanasopoulos, Maria A MA; Carmona, Sergio C SC; Stevens, Wendy S WS
Publication Date: 2015

Variant appearance in text: HR: K70R
PubMed Link: 25659108
Variant Present in the following documents:
  • Main text
  • pone.0118145.pdf
View BVdb publication page



Inflammatory responses to infection: the Dutch contribution.

Immunology Letters
Nolte, Martijn A MA; van der Meer, Jos W M JW
Publication Date: 2014-12

Variant appearance in text: HR: K70R
PubMed Link: 25455597
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Efficacy and safety of maraviroc vs. efavirenz in treatment-naive patients with HIV-1: 5-year findings.

Aids (London, England)
Cooper, David A DA; Heera, Jayvant J; Ive, Prudence P; Botes, Mariette M; Dejesus, Edwin E; Burnside, Robert R; Clumeck, Nathan N; Walmsley, Sharon S; Lazzarin, Adriano A; Mukwaya, Geoffrey G; Saag, Michael M; van Der Ryst, Elna E
Publication Date: 2014-03-13

Variant appearance in text: HR: K70R
PubMed Link: 24983542
Variant Present in the following documents:
  • aids-28-717.pdf
View BVdb publication page



Impact of HIV drug resistance on virologic and immunologic failure and mortality in a cohort of patients on antiretroviral therapy in China.

Aids (London, England)
Liao, Lingjie L; Xing, Hui H; Su, Bin B; Wang, Zhe Z; Ruan, Yuhua Y; Wang, Xia X; Liu, Zhendong Z; Lu, Yanan Y; Yang, Shimei S; Zhao, Quanbi Q; Vermund, Sten H SH; Chen, Ray Y RY; Shao, Yiming Y
Publication Date: 2013-07-17

Variant appearance in text: HR: K70R
PubMed Link: 23803794
Variant Present in the following documents:
  • Main text
  • aids-27-1815.pdf
View BVdb publication page



Long-term virologic response and genotypic resistance mutations in HIV-1 infected Kenyan children on combination antiretroviral therapy.

Journal Of Acquired Immune Deficiency Syndromes (1999)
Wamalwa, Dalton C DC; Lehman, Dara A DA; Benki-Nugent, Sarah S; Gasper, Melanie A MA; Gichohi, Richard R; Maleche-Obimbo, Elizabeth E; Farquhar, Carey C; John-Stewart, Grace C GC; Overbaugh, Julie J
Publication Date: 2013-03-01

Variant appearance in text: HR: K70R
PubMed Link: 23196827
Variant Present in the following documents:
  • Main text
View BVdb publication page



Advances in antiretroviral therapy.

Topics In Antiviral Medicine
Olender, Susan S; Wilkin, Timothy J TJ; Taylor, Barbara S BS; Hammer, Scott M SM
Publication Date: 2012

Variant appearance in text: HR: K70R
PubMed Link: 22710908
Variant Present in the following documents:
  • Main text
View BVdb publication page



It is time to consider third-line options in antiretroviral-experienced paediatric patients?

Journal Of The International Aids Society
Zyl, Gert U van GU; Rabie, Helena H; Nuttall, James J JJ; Cotton, Mark F MF
Publication Date: 2011-11-15

Variant appearance in text: HR: K70R
PubMed Link: 22085598
Variant Present in the following documents:
  • Main text
  • 1758-2652-14-55.pdf
View BVdb publication page



Abacavir/lamivudine versus tenofovir DF/emtricitabine as part of combination regimens for initial treatment of HIV: final results.

The Journal Of Infectious Diseases
Sax, Paul E PE; Tierney, Camlin C; Collier, Ann C AC; Daar, Eric S ES; Mollan, Katie K; Budhathoki, Chakra C; Godfrey, Catherine C; Jahed, Nasreen C NC; Myers, Laurie L; Katzenstein, David D; Farajallah, Awny A; Rooney, James F JF; Ha, Belinda B; Woodward, William C WC; Feinberg, Judith J; Tashima, Karen K; Murphy, Robert L RL; Fischl, Margaret A MA; ,
Publication Date: 2011-10-15

Variant appearance in text: HR: K70R
PubMed Link: 21917892
Variant Present in the following documents:
  • Main text
View BVdb publication page



Risk of triple-class virological failure in children with HIV: a retrospective cohort study.

Lancet (London, England)
, ; Castro, Hannah H; Judd, Ali A; Gibb, Diana M DM; Butler, Karina K; Lodwick, Rebecca K RK; van Sighem, Ard A; Ramos, Jose T JT; Warsawski, Josiane J; Thorne, Claire C; Noguera-Julian, Antoni A; Obel, Niels N; Costagliola, Dominique D; Tookey, Pat A PA; Colin, Céline C; Kjaer, Jesper J; Grarup, Jesper J; Chene, Genevieve G; Phillips, Andrew A
Publication Date: 2011-05-07

Variant appearance in text: HR: K70R
PubMed Link: 21511330
Variant Present in the following documents:
  • Main text
View BVdb publication page



Outcomes of Universal Access to Antiretroviral Therapy (ART) in Georgia.

Aids Research And Treatment
Tsertsvadze, Tengiz T; Chkhartishvili, Nikoloz N; Sharvadze, Lali L; Dvali, Natia N; Chokoshvili, Otar O; Gabunia, Pati P; Abutidze, Akaki A; Nelson, Kenrad K; Dehovitz, Jack J; Del Rio, Carlos C
Publication Date: 2011

Variant appearance in text: HR: K70R
PubMed Link: 21490781
Variant Present in the following documents:
  • Main text
  • ART2011-621078.pdf
View BVdb publication page



The role of toxicity-related regimen changes in the development of antiretroviral resistance.

Aids Research And Human Retroviruses
Nevin, Christa R CR; Ye, Jiatao J; Aban, Inmaculada I; Mugavero, Michael J MJ; Jackson, David D; Lin, Hui-Yi HY; Allison, Jeroan J; Raper, James L JL; Saag, Michael S MS; Willig, James H JH
Publication Date: 2011-09

Variant appearance in text: HR: K70R
PubMed Link: 21342052
Variant Present in the following documents:
  • Main text
View BVdb publication page



Atazanavir plus ritonavir or efavirenz as part of a 3-drug regimen for initial treatment of HIV-1.

Annals Of Internal Medicine
Daar, Eric S ES; Tierney, Camlin C; Fischl, Margaret A MA; Sax, Paul E PE; Mollan, Katie K; Budhathoki, Chakra C; Godfrey, Catherine C; Jahed, Nasreen C NC; Myers, Laurie L; Katzenstein, David D; Farajallah, Awny A; Rooney, James F JF; Pappa, Keith A KA; Woodward, William C WC; Patterson, Kristine K; Bolivar, Hector H; Benson, Constance A CA; Collier, Ann C AC; ,
Publication Date: 2011-04-05

Variant appearance in text: HR: K70R
PubMed Link: 21320923
Variant Present in the following documents:
  • Main text
View BVdb publication page



Utilization of a deoxynucleoside diphosphate substrate by HIV reverse transcriptase.

Plos One
Garforth, Scott J SJ; Parniak, Michael A MA; Prasad, Vinayaka R VR
Publication Date: 2008-04-30

Variant appearance in text: HR: K70R
PubMed Link: 18446195
Variant Present in the following documents:
  • Main text
  • pone.0002074.pdf
View BVdb publication page



Impact of genotypic drug resistance mutations on clinical and immunological outcomes in HIV-infected adults on HAART in West Africa.

Aids (London, England)
Seyler, Catherine C; Adjé-Touré, Christiane C; Messou, Eugène E; Dakoury-Dogbo, Nicole N; Rouet, François F; Gabillard, Delphine D; Nolan, Monica M; Toure, Siaka S; Anglaret, Xavier X
Publication Date: 2007-05-31

Variant appearance in text: HR: K70R
PubMed Link: 17502726
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mechanism of anti-human immunodeficiency virus activity of beta-D-6-cyclopropylamino-2',3'-didehydro-2',3'-dideoxyguanosine.

Antimicrobial Agents And Chemotherapy
Ray, Adrian S AS; Hernandez-Santiago, Brenda I BI; Mathew, Judy S JS; Murakami, Eisuke E; Bozeman, Carey C; Xie, Meng-Yu MY; Dutschman, Ginger E GE; Gullen, Elizabeth E; Yang, Zhenjun Z; Hurwitz, Selwyn S; Cheng, Yung-Chi YC; Chu, Chung K CK; McClure, Harold H; Schinazi, Raymond F RF; Anderson, Karen S KS
Publication Date: 2005-05

Variant appearance in text: HR: K70R
PubMed Link: 15855524
Variant Present in the following documents:
  • Main text
View BVdb publication page