EPHX2 c.307C>T ;(p.R103C)

Variant ID: 8-27361241-C-T

NM_001979.5(EPHX2):c.307C>T;(p.R103C)

This variant was identified in 17 publications

View GRCh38 version.




Publications:


Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient.

Cancer Research Communications
Valentine, Henkel H; Aiken, William W; Morrison, Belinda B; Zhao, Ziran Z; Fowle, Holly H; Wasserman, Jason S JS; Thompson, Elon E; Chin, Warren W; Young, Mark M; Clarke, Shannique S; Gibbs, Denise D; Harrison, Sharon S; McLaughlin, Wayne W; Kwok, Tim T; Jin, Fang F; Campbell, Kerry S KS; Horvath, Anelia A; Thompson, Rory R; Lee, Norman H NH; Zhou, Yan Y; Graña, Xavier X; Ragin, Camille C; Badal, Simone S
Publication Date: 2022-11

Variant appearance in text: EPHX2: R103C; rs17057255
PubMed Link: 36643868
Variant Present in the following documents:
  • crc-22-0245-s07.xlsx, sheet 1
View BVdb publication page



Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Translational And Clinical Pharmacology
Kim, Byungwook B; Yoon, Deok Yong DY; Lee, SeungHwan S; Jang, In-Jin IJ; Yu, Kyung-Sang KS; Cho, Joo-Youn JY; Oh, Jaeseong J
Publication Date: 2021-09

Variant appearance in text: EPHX2: 307C>T; R103C; rs17057255
PubMed Link: 34621706
Variant Present in the following documents:
  • tcp-29-135-s001.xls, sheet 1
View BVdb publication page



The Co-existence of ADHD With Autism in Saudi Children: An Analysis Using Next-Generation DNA Sequencing.

Frontiers In Genetics
Bogari, Neda M NM; Al-Allaf, Faisal A FA; Aljohani, Ashwag A; Taher, Mohiuddin M MM; Qutub, Nermeen A NA; Alhelfawi, Suhair S; Alobaidi, Amal A; Alqudah, Derar M DM; Banni, Hussain H; Dairi, Ghida G; Amin, Amr A AA
Publication Date: 2020

Variant appearance in text: EPHX2: 307C>T; Arg103Cys; rs17057255
PubMed Link: 33384710
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Multifaceted Role of Epoxide Hydrolases in Human Health and Disease.

International Journal Of Molecular Sciences
Gautheron, Jérémie J; Jéru, Isabelle I
Publication Date: 2020-12-22

Variant appearance in text: EPHX2: 307C>T; Arg103Cys
PubMed Link: 33374956
Variant Present in the following documents:
  • Main text
View BVdb publication page



Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products.

Journal Of Medicinal Chemistry
Sun, Cheng-Peng CP; Zhang, Xin-Yue XY; Morisseau, Christophe C; Hwang, Sung Hee SH; Zhang, Zhan-Jun ZJ; Hammock, Bruce D BD; Ma, Xiao-Chi XC
Publication Date: 2021-01-14

Variant appearance in text: EPHX2: R103C
PubMed Link: 33369424
Variant Present in the following documents:
  • Main text
View BVdb publication page



Epoxy Fatty Acids Are Promising Targets for Treatment of Pain, Cardiovascular Disease and Other Indications Characterized by Mitochondrial Dysfunction, Endoplasmic Stress and Inflammation.

Advances In Experimental Medicine And Biology
McReynolds, Cindy C; Morisseau, Christophe C; Wagner, Karen K; Hammock, Bruce B
Publication Date: 2020

Variant appearance in text: EPHX2: R103C
PubMed Link: 32894508
Variant Present in the following documents:
  • Main text
View BVdb publication page



A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.

Scientific Reports
Stringer, Brett W BW; Day, Bryan W BW; D'Souza, Rochelle C J RCJ; Jamieson, Paul R PR; Ensbey, Kathleen S KS; Bruce, Zara C ZC; Lim, Yi Chieh YC; Goasdoué, Kate K; Offenhäuser, Carolin C; Akgül, Seçkin S; Allan, Suzanne S; Robertson, Thomas T; Lucas, Peter P; Tollesson, Gert G; Campbell, Scott S; Winter, Craig C; Do, Hongdo H; Dobrovic, Alexander A; Inglis, Po-Ling PL; Jeffree, Rosalind L RL; Johns, Terrance G TG; Boyd, Andrew W AW
Publication Date: 2019-03-20

Variant appearance in text: EPHX2: R103C; rs17057255
PubMed Link: 30894629
Variant Present in the following documents:
  • 41598_2019_41277_MOESM4_ESM.xlsx, sheet 2
View BVdb publication page



Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One
Holehouse, Alex S AS; Naegle, Kristen M KM
Publication Date: 2015

Variant appearance in text: rs17057255
PubMed Link: 26659599
Variant Present in the following documents:
  • pone.0144692.s002.xlsx, sheet 1
View BVdb publication page



The Affymetrix DMET Plus platform reveals unique distribution of ADME-related variants in ethnic Arabs.

Disease Markers
Wakil, Salma M SM; Nguyen, Cao C; Muiya, Nzioka P NP; Andres, Editha E; Lykowska-Tarnowska, Agnieszka A; Baz, Batoul B; Tahir, Asma I AI; Meyer, Brian F BF; Morahan, Grant G; Dzimiri, Nduna N
Publication Date: 2015

Variant appearance in text: rs17057255
PubMed Link: 25802476
Variant Present in the following documents:
  • 542543.f1.xlsx, sheet 1
View BVdb publication page



Whole-genome sequencing of the world's oldest people.

Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Publication Date: 2014

Variant appearance in text: EPHX2: R103C; rs17057255
PubMed Link: 25390934
Variant Present in the following documents:
  • pone.0112430.s004.xlsx, sheet 1
View BVdb publication page



De novo mutations in moderate or severe intellectual disability.

Plos Genetics
Hamdan, Fadi F FF; Srour, Myriam M; Capo-Chichi, Jose-Mario JM; Daoud, Hussein H; Nassif, Christina C; Patry, Lysanne L; Massicotte, Christine C; Ambalavanan, Amirthagowri A; Spiegelman, Dan D; Diallo, Ousmane O; Henrion, Edouard E; Dionne-Laporte, Alexandre A; Fougerat, Anne A; Pshezhetsky, Alexey V AV; Venkateswaran, Sunita S; Rouleau, Guy A GA; Michaud, Jacques L JL
Publication Date: 2014-10

Variant appearance in text: EPHX2: R103C; rs17057255
PubMed Link: 25356899
Variant Present in the following documents:
  • pgen.1004772.s004.xlsx, sheet 19
View BVdb publication page



The RPTEC/TERT1 cell line models key renal cell responses to the environmental toxicants, benzo[a]pyrene and cadmium.

Toxicology Reports
Simon, B R BR; Wilson, M J MJ; Wickliffe, J K JK
Publication Date: 2014

Variant appearance in text: rs17057255
PubMed Link: 25126521
Variant Present in the following documents:
  • mmc1.xls, sheet 1
View BVdb publication page



Inhibition of soluble epoxide hydrolase preserves cardiomyocytes: role of STAT3 signaling.

American Journal Of Physiology. Heart And Circulatory Physiology
Merkel, Matthias J MJ; Liu, Lijuan L; Cao, Zhiping Z; Packwood, William W; Young, Jennifer J; Alkayed, Nabil J NJ; Van Winkle, Donna M DM
Publication Date: 2010-02

Variant appearance in text: EPHX2: Arg103Cys
PubMed Link: 20008276
Variant Present in the following documents:
  • Main text
View BVdb publication page



Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience
Koerner, Ines P IP; Jacks, Rachel R; DeBarber, Andrea E AE; Koop, Dennis D; Mao, Peizhong P; Grant, David F DF; Alkayed, Nabil J NJ
Publication Date: 2007-04-25

Variant appearance in text: EPHX2: Arg103Cys
PubMed Link: 17460077
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study.

Human Molecular Genetics
Lee, Craig R CR; North, Kari E KE; Bray, Molly S MS; Fornage, Myriam M; Seubert, John M JM; Newman, John W JW; Hammock, Bruce D BD; Couper, David J DJ; Heiss, Gerardo G; Zeldin, Darryl C DC
Publication Date: 2006-05-15

Variant appearance in text: EPHX2: R103C
PubMed Link: 16595607
Variant Present in the following documents:
  • Main text
View BVdb publication page



The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke.

Human Molecular Genetics
Fornage, Myriam M; Lee, Craig R CR; Doris, Peter A PA; Bray, Molly S MS; Heiss, Gerardo G; Zeldin, Darryl C DC; Boerwinkle, Eric E
Publication Date: 2005-10-01

Variant appearance in text: EPHX2: R103C
PubMed Link: 16115816
Variant Present in the following documents:
  • Main text
View BVdb publication page