CLU c.97+306G>C

Variant ID: 8-27467686-C-G

NM_001831.3(CLU):c.97+306G>C

This variant was identified in 91 publications

View GRCh38 version.




Publications:


Complexity of Sex Differences and Their Impact on Alzheimer's Disease.

Biomedicines
Kadlecova, Marion M; Freude, Kristine K; Haukedal, Henriette H
Publication Date: 2023-04-24

Variant appearance in text: rs9331896
PubMed Link: 37238932
Variant Present in the following documents:
  • biomedicines-11-01261.pdf
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Association of candidate genetic variants and circulating levels of ApoE/ApoJ with common neuroimaging features of cerebral amyloid angiopathy.

Frontiers In Aging Neuroscience
Bonaterra-Pastra, Anna A; Benítez, Sònia S; Pancorbo, Olalla O; Rodríguez-Luna, David D; Vert, Carla C; Rovira, Alex A; Freijo, M Mar MM; Tur, Silvia S; Martínez-Zabaleta, Maite M; Cardona Portela, Pere P; Vera, Rocío R; Lebrato-Hernández, Lucia L; Arenillas, Juan F JF; Pérez-Sánchez, Soledad S; Domínguez-Mayoral, Ana A; Fàbregas, Joan Martí JM; Mauri, Gerard G; Montaner, Joan J; Sánchez-Quesada, Jose Luis JL; Hernández-Guillamon, Mar M
Publication Date: 2023

Variant appearance in text: rs9331896
PubMed Link: 37113571
Variant Present in the following documents:
  • Main text
  • fnagi-15-1134399.pdf
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Deep learning-based polygenic risk analysis for Alzheimer's disease prediction.

Communications Medicine
Zhou, Xiaopu X; Chen, Yu Y; Ip, Fanny C F FCF; Jiang, Yuanbing Y; Cao, Han H; Lv, Ge G; Zhong, Huan H; Chen, Jiahang J; Ye, Tao T; Chen, Yuewen Y; Zhang, Yulin Y; Ma, Shuangshuang S; Lo, Ronnie M N RMN; Tong, Estella P S EPS; , ; Mok, Vincent C T VCT; Kwok, Timothy C Y TCY; Guo, Qihao Q; Mok, Kin Y KY; Shoai, Maryam M; Hardy, John J; Chen, Lei L; Fu, Amy K Y AKY; Ip, Nancy Y NY
Publication Date: 2023-04-06

Variant appearance in text: rs9331896
PubMed Link: 37024668
Variant Present in the following documents:
  • Main text
  • 43856_2023_Article_269.pdf
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Cell type-specific histone acetylation profiling of Alzheimer's disease subjects and integration with genetics.

Frontiers In Molecular Neuroscience
Ramamurthy, Easwaran E; Welch, Gwyneth G; Cheng, Jemmie J; Yuan, Yixin Y; Gunsalus, Laura L; Bennett, David A DA; Tsai, Li-Huei LH; Pfenning, Andreas R AR
Publication Date: 2022

Variant appearance in text: rs9331896
PubMed Link: 36683855
Variant Present in the following documents:
  • Main text
  • fnmol-15-948456.pdf
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Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer's disease related proteins.

Molecular Neurodegeneration
Oatman, Stephanie R SR; Reddy, Joseph S JS; Quicksall, Zachary Z; Carrasquillo, Minerva M MM; Wang, Xue X; Liu, Chia-Chen CC; Yamazaki, Yu Y; Nguyen, Thuy T TT; Malphrus, Kimberly K; Heckman, Michael M; Biswas, Kristi K; Nho, Kwangsik K; Baker, Matthew M; Martens, Yuka A YA; Zhao, Na N; Kim, Jun Pyo JP; Risacher, Shannon L SL; Rademakers, Rosa R; Saykin, Andrew J AJ; DeTure, Michael M; Murray, Melissa E ME; Kanekiyo, Takahisa T; , ; Dickson, Dennis W DW; Bu, Guojun G; Allen, Mariet M; Ertekin-Taner, Nilüfer N
Publication Date: 2023-01-07

Variant appearance in text: rs9331896
PubMed Link: 36609403
Variant Present in the following documents:
  • Main text
  • 13024_2022_Article_592.pdf
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The impact of increasing levels of blood C-reactive protein on the inflammatory loci SPI1 and CD33 in Alzheimer's disease.

Translational Psychiatry
Huang, Jinghan J; Tao, Qiushan Q; Ang, Ting Fang Alvin TFA; Farrell, John J; Zhu, Congcong C; Wang, Yixuan Y; Stein, Thor D TD; Lunetta, Kathryn L KL; Massaro, Joseph J; Mez, Jesse J; Au, Rhoda R; Farrer, Lindsay A LA; Qiu, Wei Qiao WQ; Zhang, Xiaoling X; ,
Publication Date: 2022-12-22

Variant appearance in text: rs9331896
PubMed Link: 36550123
Variant Present in the following documents:
  • Main text
  • 41398_2022_Article_2281.pdf
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Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer's disease.

Cell Reports
Xu, Jielin J; Mao, Chengsheng C; Hou, Yuan Y; Luo, Yuan Y; Binder, Jessica L JL; Zhou, Yadi Y; Bekris, Lynn M LM; Shin, Jiyoung J; Hu, Ming M; Wang, Fei F; Eng, Charis C; Oprea, Tudor I TI; Flanagan, Margaret E ME; Pieper, Andrew A AA; Cummings, Jeffrey J; Leverenz, James B JB; Cheng, Feixiong F
Publication Date: 2022-11-29

Variant appearance in text: rs9331896
PubMed Link: 36450252
Variant Present in the following documents:
  • Main text
  • nihms-1854082.pdf
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A scalable Bayesian functional GWAS method accounting for multivariate quantitative functional annotations with applications for studying Alzheimer disease.

Hgg Advances
Chen, Junyu J; Wang, Lei L; De Jager, Philip L PL; Bennett, David A DA; Buchman, Aron S AS; Yang, Jingjing J
Publication Date: 2022-10-13

Variant appearance in text: rs9331896
PubMed Link: 36204489
Variant Present in the following documents:
  • Main text
  • mmc2.pdf
  • main.pdf
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The Influence of Clusterin Glycosylation Variability on Selected Pathophysiological Processes in the Human Body.

Oxidative Medicine And Cellular Longevity
Janiszewska, Ewa E; Kmieciak, Agnieszka A; Kacperczyk, Monika M; Witkowska, Aleksandra A; Kratz, Ewa Maria EM
Publication Date: 2022

Variant appearance in text: rs9331896
PubMed Link: 36071866
Variant Present in the following documents:
  • OMCL2022-7657876.pdf
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Identifying genetic markers enriched by brain imaging endophenotypes in Alzheimer's disease.

Bmc Medical Genomics
Kim, Mansu M; Wu, Ruiming R; Yao, Xiaohui X; Saykin, Andrew J AJ; Moore, Jason H JH; Shen, Li L; ,
Publication Date: 2022-08-01

Variant appearance in text: rs9331896
PubMed Link: 35915443
Variant Present in the following documents:
  • Main text
  • 12920_2022_Article_1323.pdf
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A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer's disease and gastrointestinal tract disorders.

Communications Biology
Adewuyi, Emmanuel O EO; O'Brien, Eleanor K EK; Nyholt, Dale R DR; Porter, Tenielle T; Laws, Simon M SM
Publication Date: 2022-07-18

Variant appearance in text: rs9331896
PubMed Link: 35851147
Variant Present in the following documents:
  • 42003_2022_3607_MOESM1_ESM.pdf
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Spatiotemporal Dynamics of the Molecular Expression Pattern and Intercellular Interactions in the Glial Scar Response to Spinal Cord Injury.

Neuroscience Bulletin
Gong, Leilei L; Gu, Yun Y; Han, Xiaoxiao X; Luan, Chengcheng C; Liu, Chang C; Wang, Xinghui X; Sun, Yufeng Y; Zheng, Mengru M; Fang, Mengya M; Yang, Shuhai S; Xu, Lai L; Sun, Hualin H; Yu, Bin B; Gu, Xiaosong X; Zhou, Songlin S
Publication Date: 2022-07-05

Variant appearance in text: rs9331896
PubMed Link: 35788904
Variant Present in the following documents:
  • Main text
  • 12264_2022_Article_897.pdf
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Association of APOE-Independent Alzheimer Disease Polygenic Risk Score With Brain Amyloid Deposition in Asymptomatic Older Adults.

Neurology
Xicota, Laura L; Gyorgy, Beata B; Grenier-Boley, Benjamin B; Lecoeur, Alexandre A; Fontaine, Gaà Lle GL; Danjou, Fabrice F; Gonzalez, Jorge Samper JS; Colliot, Olivier O; Amouyel, Philippe P; Martin, Garance G; Levy, Marcel M; Villain, Nicolas N; Habert, Marie-Odile MO; Dubois, Bruno B; Lambert, Jean-Charles JC; Potier, Marie-Claude MC; ,
Publication Date: 2022-05-23

Variant appearance in text: rs9331896
PubMed Link: 35606148
Variant Present in the following documents:
  • WNL-2022-200600.pdf
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Association of Genetic Variants Linked to Late-Onset Alzheimer Disease With Cognitive Test Performance by Midlife.

Jama Network Open
Zimmerman, Scott C SC; Brenowitz, Willa D WD; Calmasini, Camilla C; Ackley, Sarah F SF; Graff, Rebecca E RE; Asiimwe, Stephen B SB; Staffaroni, Adam M AM; Hoffmann, Thomas J TJ; Glymour, M Maria MM
Publication Date: 2022-04-01

Variant appearance in text: rs9331896
PubMed Link: 35377426
Variant Present in the following documents:
  • jamanetwopen-e225491-s001.pdf
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Identification of Genetic Networks Reveals Complex Associations and Risk Trajectory Linking Mild Cognitive Impairment to Alzheimer's Disease.

Frontiers In Aging Neuroscience
Strafella, Claudia C; Caputo, Valerio V; Termine, Andrea A; Fabrizio, Carlo C; Calvino, Giulia G; Megalizzi, Domenica D; Ruffo, Paola P; Toppi, Elisa E; Banaj, Nerisa N; Bassi, Andrea A; Bossù, Paola P; Caltagirone, Carlo C; Spalletta, Gianfranco G; Giardina, Emiliano E; Cascella, Raffaella R
Publication Date: 2022

Variant appearance in text: rs9331896
PubMed Link: 35250545
Variant Present in the following documents:
  • Main text
  • fnagi-14-821789.pdf
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Genetic Insights into the Impact of Complement in Alzheimer's Disease.

Genes
Torvell, Megan M; Carpanini, Sarah M SM; Daskoulidou, Nikoleta N; Byrne, Robert A J RAJ; Sims, Rebecca R; Morgan, B Paul BP
Publication Date: 2021-12-15

Variant appearance in text: rs9331896
PubMed Link: 34946939
Variant Present in the following documents:
  • Main text
  • genes-12-01990.pdf
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Genetic Insights into the Impact of Complement in Alzheimer's Disease.

Genes
Torvell, Megan M; Carpanini, Sarah M SM; Daskoulidou, Nikoleta N; Byrne, Robert A J RAJ; Sims, Rebecca R; Morgan, B Paul BP
Publication Date: 2021-12-15

Variant appearance in text: rs9331896
PubMed Link: 34946939
Variant Present in the following documents:
  • Main text
  • genes-12-01990.pdf
View BVdb publication page



Genomics and Functional Genomics of Alzheimer's Disease.

Neurotherapeutics : The Journal Of The American Society For Experimental Neurotherapeutics
Kamboh, M Ilyas MI
Publication Date: 2022-01

Variant appearance in text: rs9331896
PubMed Link: 34935119
Variant Present in the following documents:
  • Main text
  • 13311_2021_Article_1152.pdf
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Genetic signature of human longevity in PKC and NF-κB signaling.

Aging Cell
Ryu, Seungjin S; Han, Jeehae J; Norden-Krichmar, Trina M TM; Zhang, Quanwei Q; Lee, Seunggeun S; Zhang, Zhengdong Z; Atzmon, Gil G; Niedernhofer, Laura J LJ; Robbins, Paul D PD; Barzilai, Nir N; Schork, Nicholas J NJ; Suh, Yousin Y
Publication Date: 2021-07

Variant appearance in text: rs9331896
PubMed Link: 34197020
Variant Present in the following documents:
  • ACEL-20-e13362.pdf
View BVdb publication page



Immune System and Neuroinflammation in Idiopathic Parkinson's Disease: Association Analysis of Genetic Variants and miRNAs Interactions.

Frontiers In Genetics
Strafella, Claudia C; Caputo, Valerio V; Termine, Andrea A; Assogna, Francesca F; Pellicano, Clelia C; Pontieri, Francesco E FE; Macchiusi, Lucia L; Minozzi, Giulietta G; Gambardella, Stefano S; Centonze, Diego D; Bossù, Paola P; Spalletta, Gianfranco G; Caltagirone, Carlo C; Giardina, Emiliano E; Cascella, Raffaella R
Publication Date: 2021

Variant appearance in text: rs9331896
PubMed Link: 34149802
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic Determinants Highlight the Existence of Shared Etiopathogenetic Mechanisms Characterizing Age-Related Macular Degeneration and Neurodegenerative Disorders.

Frontiers In Neurology
Strafella, Claudia C; Caputo, Valerio V; Termine, Andrea A; Fabrizio, Carlo C; Ruffo, Paola P; Potenza, Saverio S; Cusumano, Andrea A; Ricci, Federico F; Caltagirone, Carlo C; Giardina, Emiliano E; Cascella, Raffaella R
Publication Date: 2021

Variant appearance in text: rs9331896
PubMed Link: 34135841
Variant Present in the following documents:
  • Main text
  • fneur-12-626066.pdf
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Novel Alzheimer's disease risk variants identified based on whole-genome sequencing of APOE ε4 carriers.

Translational Psychiatry
Park, Jong-Ho JH; Park, Inho I; Youm, Emilia Moonkyung EM; Lee, Sejoon S; Park, June-Hee JH; Lee, Jongan J; Lee, Dong Young DY; Byun, Min Soo MS; Lee, Jun Ho JH; Yi, Dahyun D; Chung, Sun Ju SJ; Park, Kye Won KW; Choi, Nari N; Kim, Seong Yoon SY; Yoon, Woon W; An, Hoyoung H; Kim, Ki Woong KW; Choi, Seong Hye SH; Jeong, Jee Hyang JH; Kim, Eun-Joo EJ; Kang, Hyojin H; Lee, Junehawk J; Kim, Younghoon Y; Lee, Eunjung Alice EA; Seo, Sang Won SW; Na, Duk L DL; Kim, Jong-Won JW
Publication Date: 2021-05-19

Variant appearance in text: rs9331896
PubMed Link: 34011927
Variant Present in the following documents:
  • Main text
  • 41398_2021_Article_1412.pdf
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Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue.

Translational Psychiatry
Patel, Devanshi D; Zhang, Xiaoling X; Farrell, John J JJ; Chung, Jaeyoon J; Stein, Thor D TD; Lunetta, Kathryn L KL; Farrer, Lindsay A LA
Publication Date: 2021-04-27

Variant appearance in text: rs9331896
PubMed Link: 33907181
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic Variability in Molecular Pathways Implicated in Alzheimer's Disease: A Comprehensive Review.

Frontiers In Aging Neuroscience
Vogrinc, David D; Goričar, Katja K; Dolžan, Vita V
Publication Date: 2021

Variant appearance in text: rs9331896
PubMed Link: 33815092
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Impact of Complement Genes on the Risk of Late-Onset Alzheimer's Disease.

Genes
Carpanini, Sarah M SM; Harwood, Janet C JC; Baker, Emily E; Torvell, Megan M; The Gerad Consortium, ; Sims, Rebecca R; Williams, Julie J; Morgan, B Paul BP
Publication Date: 2021-03-20

Variant appearance in text: rs9331896
PubMed Link: 33804666
Variant Present in the following documents:
  • Main text
  • genes-12-00443.pdf
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A Non-APOE Polygenic Risk Score for Alzheimer's Disease Is Associated With Cerebrospinal Fluid Neurofilament Light in a Representative Sample of Cognitively Unimpaired 70-Year Olds.

The Journals Of Gerontology. Series A, Biological Sciences And Medical Sciences
Skoog, Ingmar I; Kern, Silke S; Najar, Jenna J; Guerreiro, Rita R; Bras, Jose J; Waern, Margda M; Zetterberg, Henrik H; Blennow, Kaj K; Zettergren, Anna A
Publication Date: 2021-05-22

Variant appearance in text: rs9331896
PubMed Link: 33512503
Variant Present in the following documents:
  • glab030_suppl_supplementary_table_1.pdf
View BVdb publication page



HDL Proteome and Alzheimer's Disease: Evidence of a Link.

Antioxidants (Basel, Switzerland)
Marsillach, Judit J; Adorni, Maria Pia MP; Zimetti, Francesca F; Papotti, Bianca B; Zuliani, Giovanni G; Cervellati, Carlo C
Publication Date: 2020-12-03

Variant appearance in text: rs9331896
PubMed Link: 33287338
Variant Present in the following documents:
  • Main text
  • antioxidants-09-01224.pdf
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Polygenic Risk Score of Longevity Predicts Longer Survival Across an Age Continuum.

The Journals Of Gerontology. Series A, Biological Sciences And Medical Sciences
Tesi, Niccolo' N; van der Lee, Sven J SJ; Hulsman, Marc M; Jansen, Iris E IE; Stringa, Najada N; van Schoor, Natasja M NM; Scheltens, Philip P; van der Flier, Wiesje M WM; Huisman, Martijn M; Reinders, Marcel J T MJT; Holstege, Henne H
Publication Date: 2021-04-30

Variant appearance in text: rs9331896
PubMed Link: 33216869
Variant Present in the following documents:
  • Main text
View BVdb publication page



Screening for functional transcriptional and splicing regulatory variants with GenIE.

Nucleic Acids Research
Cooper, Sarah E SE; Schwartzentruber, Jeremy J; Bello, Erica E; Coomber, Eve L EL; Bassett, Andrew R AR
Publication Date: 2020-12-16

Variant appearance in text: rs9331896
PubMed Link: 33152068
Variant Present in the following documents:
  • gkaa960.pdf
View BVdb publication page



Impact of cardiovascular risk factors and genetics on 10-year absolute risk of dementia: risk charts for targeted prevention.

European Heart Journal
Juul Rasmussen, Ida I; Rasmussen, Katrine Laura KL; Nordestgaard, Børge G BG; Tybjærg-Hansen, Anne A; Frikke-Schmidt, Ruth R
Publication Date: 2020-11-01

Variant appearance in text: rs9331896
PubMed Link: 33022702
Variant Present in the following documents:
  • Main text
  • ehaa695.pdf
View BVdb publication page



Stroke and Alzheimer's Disease: A Mendelian Randomization Study.

Frontiers In Genetics
Wang, Tao T; Ni, Qing-Bin QB; Wang, Kun K; Han, Zhifa Z; Sun, Bao-Liang BL
Publication Date: 2020

Variant appearance in text: rs9331896
PubMed Link: 32760421
Variant Present in the following documents:
  • Main text
  • fgene-11-00581.pdf
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ADNC-RS, a clinical-genetic risk score, predicts Alzheimer's pathology in autopsy-confirmed Parkinson's disease and Dementia with Lewy bodies.

Acta Neuropathologica
Dai, David L DL; Tropea, Thomas F TF; Robinson, John L JL; Suh, Eunran E; Hurtig, Howard H; Weintraub, Daniel D; Van Deerlin, Vivianna V; Lee, Edward B EB; Trojanowski, John Q JQ; Chen-Plotkin, Alice S AS
Publication Date: 2020-10

Variant appearance in text: rs9331896
PubMed Link: 32749525
Variant Present in the following documents:
  • Main text
View BVdb publication page



MAPT haplotype-stratified GWAS reveals differential association for AD risk variants.

Alzheimer'S & Dementia : The Journal Of The Alzheimer'S Association
Strickland, Samantha L SL; Reddy, Joseph S JS; Allen, Mariet M; N'songo, Aurelie A; Burgess, Jeremy D JD; Corda, Morgane M MM; Ballard, Travis T; Wang, Xue X; Carrasquillo, Minerva M MM; Biernacka, Joanna M JM; Jenkins, Gregory D GD; Mukherjee, Shubhabrata S; Boehme, Kevin K; Crane, Paul P; Kauwe, John S JS; Ertekin-Taner, Nilüfer N; ,
Publication Date: 2020-07

Variant appearance in text: rs9331896
PubMed Link: 32400971
Variant Present in the following documents:
  • Main text
  • ALZ-16-983.pdf
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Genetic risk for Alzheimer disease in children: Evidence from early-life IQ and brain white-matter microstructure.

Genes, Brain, And Behavior
Vinueza-Veloz, María Fernanda MF; Martín-Román, Carlos C; Robalino-Valdivieso, María Paulina MP; White, Tonya T; Kushner, Steven A SA; De Zeeuw, Chris I CI
Publication Date: 2020-07

Variant appearance in text: rs9331896
PubMed Link: 32383552
Variant Present in the following documents:
  • Main text
View BVdb publication page



Brain-wide structural connectivity alterations under the control of Alzheimer risk genes.

International Journal Of Computational Biology And Drug Design
Yan, Jingwen J; Raja V, Vinesh V; Huang, Zhi Z; Amico, Enrico E; Nho, Kwangsik K; Fang, Shiaofeng S; Sporns, Olaf O; Wu, Yu-Chien YC; Saykin, Andrew A; Goni, Joaquin J; Shen, Li L; ,
Publication Date: 2020

Variant appearance in text: rs9331896
PubMed Link: 32095160
Variant Present in the following documents:
  • Main text
View BVdb publication page



Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs.

Plos Genetics
Ramdhani, Satesh S; Navarro, Elisa E; Udine, Evan E; Efthymiou, Anastasia G AG; Schilder, Brian M BM; Parks, Madison M; Goate, Alison A; Raj, Towfique T
Publication Date: 2020-02

Variant appearance in text: rs9331896
PubMed Link: 32012164
Variant Present in the following documents:
  • Main text
  • pgen.1008549.pdf
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Interpretation of risk loci from genome-wide association studies of Alzheimer's disease.

The Lancet. Neurology
Andrews, Shea J SJ; Fulton-Howard, Brian B; Goate, Alison A
Publication Date: 2020-04

Variant appearance in text: rs9331896
PubMed Link: 31986256
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mining Regional Imaging Genetic Associations via Voxel-wise Enrichment Analysis.

... Ieee-Embs International Conference On Biomedical And Health Informatics. Ieee-Embs International Conference On Biomedical And Health Informatics
Yao, Xiaohui X; Cong, Shan S; Yan, Jingwen J; Risacher, Shannon L SL; Saykin, Andrew J AJ; Moore, Jason H JH; Shen, Li L
Publication Date: 2019-05

Variant appearance in text: rs9331896
PubMed Link: 31742256
Variant Present in the following documents:
  • Main text
View BVdb publication page



Inferring the Molecular Mechanisms of Noncoding Alzheimer's Disease-Associated Genetic Variants.

Journal Of Alzheimer'S Disease : Jad
Amlie-Wolf, Alexandre A; Tang, Mitchell M; Way, Jessica J; Dombroski, Beth B; Jiang, Ming M; Vrettos, Nicholas N; Chou, Yi-Fan YF; Zhao, Yi Y; Kuzma, Amanda A; Mlynarski, Elisabeth E EE; Leung, Yuk Yee YY; Brown, Christopher D CD; Wang, Li-San LS; Schellenberg, Gerard D GD
Publication Date: 2019

Variant appearance in text: rs9331896
PubMed Link: 31561366
Variant Present in the following documents:
  • Main text
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Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer's disease.

Clinical Epigenetics
Konki, Mikko M; Malonzo, Maia M; Karlsson, Ida K IK; Lindgren, Noora N; Ghimire, Bishwa B; Smolander, Johannes J; Scheinin, Noora M NM; Ollikainen, Miina M; Laiho, Asta A; Elo, Laura L LL; Lönnberg, Tapio T; Röyttä, Matias M; Pedersen, Nancy L NL; Kaprio, Jaakko J; Lähdesmäki, Harri H; Rinne, Juha O JO; Lund, Riikka J RJ
Publication Date: 2019-09-02

Variant appearance in text: rs9331896
PubMed Link: 31477183
Variant Present in the following documents:
  • Main text
View BVdb publication page



The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion.

Acta Neuropathologica
Li, Zeran Z; Farias, Fabiana H G FHG; Dube, Umber U; Del-Aguila, Jorge L JL; Mihindukulasuriya, Kathie A KA; Fernandez, Maria Victoria MV; Ibanez, Laura L; Budde, John P JP; Wang, Fengxian F; Lake, Allison M AM; Deming, Yuetiva Y; Perez, James J; Yang, Chengran C; Bahena, Jorge A JA; Qin, Wei W; Bradley, Joseph L JL; Davenport, Richard R; Bergmann, Kristy K; Morris, John C JC; Perrin, Richard J RJ; Benitez, Bruno A BA; Dougherty, Joseph D JD; Harari, Oscar O; Cruchaga, Carlos C
Publication Date: 2020-01

Variant appearance in text: rs9331896
PubMed Link: 31456032
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic predisposition, modifiable-risk-factor profile and long-term dementia risk in the general population.

Nature Medicine
Licher, Silvan S; Ahmad, Shahzad S; Karamujić-Čomić, Hata H; Voortman, Trudy T; Leening, Maarten J G MJG; Ikram, M Arfan MA; Ikram, M Kamran MK
Publication Date: 2019-09

Variant appearance in text: rs9331896
PubMed Link: 31451782
Variant Present in the following documents:
  • EMS83726-supplement-1.pdf
View BVdb publication page



Evaluation of the Common Molecular Basis in Alzheimer's and Parkinson's Diseases.

International Journal Of Molecular Sciences
Rana, Pratip P; Franco, Edian F EF; Rao, Yug Y; Syed, Khajamoinuddin K; Barh, Debmalya D; Azevedo, Vasco V; Ramos, Rommel T J RTJ; Ghosh, Preetam P
Publication Date: 2019-07-30

Variant appearance in text: rs9331896
PubMed Link: 31366155
Variant Present in the following documents:
  • Main text
  • ijms-20-03730.pdf
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Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer's disease pathology and cognitive symptoms.

Nature Communications
Li, Peipei P; Marshall, Lee L; Oh, Gabriel G; Jakubowski, Jennifer L JL; Groot, Daniel D; He, Yu Y; Wang, Ting T; Petronis, Arturas A; Labrie, Viviane V
Publication Date: 2019-05-21

Variant appearance in text: rs9331896
PubMed Link: 31113950
Variant Present in the following documents:
  • 41467_2019_10101_MOESM1_ESM.pdf
View BVdb publication page



Clusterin in Alzheimer's Disease: Mechanisms, Genetics, and Lessons From Other Pathologies.

Frontiers In Neuroscience
Foster, Evangeline M EM; Dangla-Valls, Adrià A; Lovestone, Simon S; Ribe, Elena M EM; Buckley, Noel J NJ
Publication Date: 2019

Variant appearance in text: rs9331896
PubMed Link: 30872998
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Nature Genetics
Kunkle, Brian W BW; Grenier-Boley, Benjamin B; Sims, Rebecca R; Bis, Joshua C JC; Damotte, Vincent V; Naj, Adam C AC; Boland, Anne A; Vronskaya, Maria M; van der Lee, Sven J SJ; Amlie-Wolf, Alexandre A; Bellenguez, Céline C; Frizatti, Aura A; Chouraki, Vincent V; Martin, Eden R ER; Sleegers, Kristel K; Badarinarayan, Nandini N; Jakobsdottir, Johanna J; Hamilton-Nelson, Kara L KL; Moreno-Grau, Sonia S; Olaso, Robert R; Raybould, Rachel R; Chen, Yuning Y; Kuzma, Amanda B AB; Hiltunen, Mikko M; Morgan, Taniesha T; Ahmad, Shahzad S; Vardarajan, Badri N BN; Epelbaum, Jacques J; Hoffmann, Per P; Boada, Merce M; Beecham, Gary W GW; Garnier, Jean-Guillaume JG; Harold, Denise D; Fitzpatrick, Annette L AL; Valladares, Otto O; Moutet, Marie-Laure ML; Gerrish, Amy A; Smith, Albert V AV; Qu, Liming L; Bacq, Delphine D; Denning, Nicola N; Jian, Xueqiu X; Zhao, Yi Y; Del Zompo, Maria M; Fox, Nick C NC; Choi, Seung-Hoan SH; Mateo, Ignacio I; Hughes, Joseph T JT; Adams, Hieab H HH; Malamon, John J; Sanchez-Garcia, Florentino F; Patel, Yogen Y; Brody, Jennifer A JA; Dombroski, Beth A BA; Naranjo, Maria Candida Deniz MCD; Daniilidou, Makrina M; Eiriksdottir, Gudny G; Mukherjee, Shubhabrata S; Wallon, David D; Uphill, James J; Aspelund, Thor T; Cantwell, Laura B LB; Garzia, Fabienne F; Galimberti, Daniela D; Hofer, Edith E; Butkiewicz, Mariusz M; Fin, Bertrand B; Scarpini, Elio E; Sarnowski, Chloe C; Bush, Will S WS; Meslage, Stéphane S; Kornhuber, Johannes J; White, Charles C CC; Song, Yuenjoo Y; Barber, Robert C RC; Engelborghs, Sebastiaan S; Sordon, Sabrina S; Voijnovic, Dina D; Adams, Perrie M PM; Vandenberghe, Rik R; Mayhaus, Manuel M; Cupples, L Adrienne LA; Albert, Marilyn S MS; De Deyn, Peter P PP; Gu, Wei W; Himali, Jayanadra J JJ; Beekly, Duane D; Squassina, Alessio A; Hartmann, Annette M AM; Orellana, Adelina A; Blacker, Deborah D; Rodriguez-Rodriguez, Eloy E; Lovestone, Simon S; Garcia, Melissa E ME; Doody, Rachelle S RS; Munoz-Fernadez, Carmen C; Sussams, Rebecca R; Lin, Honghuang H; Fairchild, Thomas J TJ; Benito, Yolanda A YA; Holmes, Clive C; Karamujić-Čomić, Hata H; Frosch, Matthew P MP; Thonberg, Hakan H; Maier, Wolfgang W; Roshchupkin, Gennady G; Ghetti, Bernardino B; Giedraitis, Vilmantas V; Kawalia, Amit A; Li, Shuo S; Huebinger, Ryan M RM; Kilander, Lena L; Moebus, Susanne S; Hernández, Isabel I; Kamboh, M Ilyas MI; Brundin, RoseMarie R; Turton, James J; Yang, Qiong Q; Katz, Mindy J MJ; Concari, Letizia L; Lord, Jenny J; Beiser, Alexa S AS; Keene, C Dirk CD; Helisalmi, Seppo S; Kloszewska, Iwona I; Kukull, Walter A WA; Koivisto, Anne Maria AM; Lynch, Aoibhinn A; Tarraga, Lluís L; Larson, Eric B EB; Haapasalo, Annakaisa A; Lawlor, Brian B; Mosley, Thomas H TH; Lipton, Richard B RB; Solfrizzi, Vincenzo V; Gill, Michael M; Longstreth, W T WT; Montine, Thomas J TJ; Frisardi, Vincenza V; Diez-Fairen, Monica M; Rivadeneira, Fernando F; Petersen, Ronald C RC; Deramecourt, Vincent V; Alvarez, Ignacio I; Salani, Francesca F; Ciaramella, Antonio A; Boerwinkle, Eric E; Reiman, Eric M EM; Fievet, Nathalie N; Rotter, Jerome I JI; Reisch, Joan S JS; Hanon, Olivier O; Cupidi, Chiara C; Andre Uitterlinden, A G AG; Royall, Donald R DR; Dufouil, Carole C; Maletta, Raffaele Giovanni RG; de Rojas, Itziar I; Sano, Mary M; Brice, Alexis A; Cecchetti, Roberta R; George-Hyslop, Peter St PS; Ritchie, Karen K; Tsolaki, Magda M; Tsuang, Debby W DW; Dubois, Bruno B; Craig, David D; Wu, Chuang-Kuo CK; Soininen, Hilkka H; Avramidou, Despoina D; Albin, Roger L RL; Fratiglioni, Laura L; Germanou, Antonia A; Apostolova, Liana G LG; Keller, Lina L; Koutroumani, Maria M; Arnold, Steven E SE; Panza, Francesco F; Gkatzima, Olymbia O; Asthana, Sanjay S; Hannequin, Didier D; Whitehead, Patrice P; Atwood, Craig S CS; Caffarra, Paolo P; Hampel, Harald H; Quintela, Inés I; Carracedo, Ángel Á; Lannfelt, Lars L; Rubinsztein, David C DC; Barnes, Lisa L LL; Pasquier, Florence F; Frölich, Lutz L; Barral, Sandra S; McGuinness, Bernadette B; Beach, Thomas G TG; Johnston, Janet A JA; Becker, James T JT; Passmore, Peter P; Bigio, Eileen H EH; Schott, Jonathan M JM; Bird, Thomas D TD; Warren, Jason D JD; Boeve, Bradley F BF; Lupton, Michelle K MK; Bowen, James D JD; Proitsi, Petra P; Boxer, Adam A; Powell, John F JF; Burke, James R JR; Kauwe, John S K JSK; Burns, Jeffrey M JM; Mancuso, Michelangelo M; Buxbaum, Joseph D JD; Bonuccelli, Ubaldo U; Cairns, Nigel J NJ; McQuillin, Andrew A; Cao, Chuanhai C; Livingston, Gill G; Carlson, Chris S CS; Bass, Nicholas J NJ; Carlsson, Cynthia M CM; Hardy, John J; Carney, Regina M RM; Bras, Jose J; Carrasquillo, Minerva M MM; Guerreiro, Rita R; Allen, Mariet M; Chui, Helena C HC; Fisher, Elizabeth E; Masullo, Carlo C; Crocco, Elizabeth A EA; DeCarli, Charles C; Bisceglio, Gina G; Dick, Malcolm M; Ma, Li L; Duara, Ranjan R; Graff-Radford, Neill R NR; Evans, Denis A DA; Hodges, Angela A; Faber, Kelley M KM; Scherer, Martin M; Fallon, Kenneth B KB; Riemenschneider, Matthias M; Fardo, David W DW; Heun, Reinhard R; Farlow, Martin R MR; Kölsch, Heike H; Ferris, Steven S; Leber, Markus M; Foroud, Tatiana M TM; Heuser, Isabella I; Galasko, Douglas R DR; Giegling, Ina I; Gearing, Marla M; Hüll, Michael M; Geschwind, Daniel H DH; Gilbert, John R JR; Morris, John J; Green, Robert C RC; Mayo, Kevin K; Growdon, John H JH; Feulner, Thomas T; Hamilton, Ronald L RL; Harrell, Lindy E LE; Drichel, Dmitriy D; Honig, Lawrence S LS; Cushion, Thomas D TD; Huentelman, Matthew J MJ; Hollingworth, Paul P; Hulette, Christine M CM; Hyman, Bradley T BT; Marshall, Rachel R; Jarvik, Gail P GP; Meggy, Alun A; Abner, Erin E; Menzies, Georgina E GE; Jin, Lee-Way LW; Leonenko, Ganna G; Real, Luis M LM; Jun, Gyungah R GR; Baldwin, Clinton T CT; Grozeva, Detelina D; Karydas, Anna A; Russo, Giancarlo G; Kaye, Jeffrey A JA; Kim, Ronald R; Jessen, Frank F; Kowall, Neil W NW; Vellas, Bruno B; Kramer, Joel H JH; Vardy, Emma E; LaFerla, Frank M FM; Jöckel, Karl-Heinz KH; Lah, James J JJ; Dichgans, Martin M; Leverenz, James B JB; Mann, David D; Levey, Allan I AI; Pickering-Brown, Stuart S; Lieberman, Andrew P AP; Klopp, Norman N; Lunetta, Kathryn L KL; Wichmann, H-Erich HE; Lyketsos, Constantine G CG; Morgan, Kevin K; Marson, Daniel C DC; Brown, Kristelle K; Martiniuk, Frank F; Medway, Christopher C; Mash, Deborah C DC; Nöthen, Markus M MM; Masliah, Eliezer E; Hooper, Nigel M NM; McCormick, Wayne C WC; Daniele, Antonio A; McCurry, Susan M SM; Bayer, Anthony A; McDavid, Andrew N AN; Gallacher, John J; McKee, Ann C AC; van den Bussche, Hendrik H; Mesulam, Marsel M; Brayne, Carol C; Miller, Bruce L BL; Riedel-Heller, Steffi S; Miller, Carol A CA; Miller, Joshua W JW; Al-Chalabi, Ammar A; Morris, John C JC; Shaw, Christopher E CE; Myers, Amanda J AJ; Wiltfang, Jens J; O'Bryant, Sid S; Olichney, John M JM; Alvarez, Victoria V; Parisi, Joseph E JE; Singleton, Andrew B AB; Paulson, Henry L HL; Collinge, John J; Perry, William R WR; Mead, Simon S; Peskind, Elaine E; Cribbs, David H DH; Rossor, Martin M; Pierce, Aimee A; Ryan, Natalie S NS; Poon, Wayne W WW; Nacmias, Benedetta B; Potter, Huntington H; Sorbi, Sandro S; Quinn, Joseph F JF; Sacchinelli, Eleonora E; Raj, Ashok A; Spalletta, Gianfranco G; Raskind, Murray M; Caltagirone, Carlo C; Bossù, Paola P; Orfei, Maria Donata MD; Reisberg, Barry B; Clarke, Robert R; Reitz, Christiane C; Smith, A David AD; Ringman, John M JM; Warden, Donald D; Roberson, Erik D ED; Wilcock, Gordon G; Rogaeva, Ekaterina E; Bruni, Amalia Cecilia AC; Rosen, Howard J HJ; Gallo, Maura M; Rosenberg, Roger N RN; Ben-Shlomo, Yoav Y; Sager, Mark A MA; Mecocci, Patrizia P; Saykin, Andrew J AJ; Pastor, Pau P; Cuccaro, Michael L ML; Vance, Jeffery M JM; Schneider, Julie A JA; Schneider, Lori S LS; Slifer, Susan S; Seeley, William W WW; Smith, Amanda G AG; Sonnen, Joshua A JA; Spina, Salvatore S; Stern, Robert A RA; Swerdlow, Russell H RH; Tang, Mitchell M; Tanzi, Rudolph E RE; Trojanowski, John Q JQ; Troncoso, Juan C JC; Van Deerlin, Vivianna M VM; Van Eldik, Linda J LJ; Vinters, Harry V HV; Vonsattel, Jean Paul JP; Weintraub, Sandra S; Welsh-Bohmer, Kathleen A KA; Wilhelmsen, Kirk C KC; Williamson, Jennifer J; Wingo, Thomas S TS; Woltjer, Randall L RL; Wright, Clinton B CB; Yu, Chang-En CE; Yu, Lei L; Saba, Yasaman Y; Pilotto, Alberto A; Bullido, Maria J MJ; Peters, Oliver O; Crane, Paul K PK; Bennett, David D; Bosco, Paola P; Coto, Eliecer E; Boccardi, Virginia V; De Jager, Phil L PL; Lleo, Alberto A; Warner, Nick N; Lopez, Oscar L OL; Ingelsson, Martin M; Deloukas, Panagiotis P; Cruchaga, Carlos C; Graff, Caroline C; Gwilliam, Rhian R; Fornage, Myriam M; Goate, Alison M AM; Sanchez-Juan, Pascual P; Kehoe, Patrick G PG; Amin, Najaf N; Ertekin-Taner, Nilifur N; Berr, Claudine C; Debette, Stéphanie S; Love, Seth S; Launer, Lenore J LJ; Younkin, Steven G SG; Dartigues, Jean-Francois JF; Corcoran, Chris C; Ikram, M Arfan MA; Dickson, Dennis W DW; Nicolas, Gael G; Campion, Dominique D; Tschanz, JoAnn J; Schmidt, Helena H; Hakonarson, Hakon H; Clarimon, Jordi J; Munger, Ron R; Schmidt, Reinhold R; Farrer, Lindsay A LA; Van Broeckhoven, Christine C; C O'Donovan, Michael M; DeStefano, Anita L AL; Jones, Lesley L; Haines, Jonathan L JL; Deleuze, Jean-Francois JF; Owen, Michael J MJ; Gudnason, Vilmundur V; Mayeux, Richard R; Escott-Price, Valentina V; Psaty, Bruce M BM; Ramirez, Alfredo A; Wang, Li-San LS; Ruiz, Agustin A; van Duijn, Cornelia M CM; Holmans, Peter A PA; Seshadri, Sudha S; Williams, Julie J; Amouyel, Phillippe P; Schellenberg, Gerard D GD; Lambert, Jean-Charles JC; Pericak-Vance, Margaret A MA; , ; , ; , ; ,
Publication Date: 2019-03

Variant appearance in text: rs9331896
PubMed Link: 30820047
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Alzheimer's disease as a multistage process: an analysis from a population-based cohort study.

Aging
Licher, Silvan S; van der Willik, Kimberly D KD; Vinke, Elisabeth J EJ; Yilmaz, Pinar P; Fani, Lana L; Schagen, Sanne B SB; Ikram, M Arfan MA; Ikram, M Kamran MK
Publication Date: 2019-02-27

Variant appearance in text: rs9331896
PubMed Link: 30811346
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  • aging-11-101816-s001.pdf
  • aging-11-101816.pdf
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Age-Related Differences in Brain Morphology and the Modifiers in Middle-Aged and Older Adults.

Cerebral Cortex (New York, N.Y. : 1991)
Zhao, Lu L; Matloff, William W; Ning, Kaida K; Kim, Hosung H; Dinov, Ivo D ID; Toga, Arthur W AW
Publication Date: 2019-09-13

Variant appearance in text: rs9331896
PubMed Link: 30535294
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Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs.

Neurobiology Of Aging
Katsumata, Yuriko Y; Nelson, Peter T PT; Estus, Steven S; , ; Fardo, David W DW
Publication Date: 2019-02

Variant appearance in text: rs9331896
PubMed Link: 30448613
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Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome.

Alzheimer'S & Dementia : The Journal Of The Alzheimer'S Association
MahmoudianDehkordi, Siamak S; Arnold, Matthias M; Nho, Kwangsik K; Ahmad, Shahzad S; Jia, Wei W; Xie, Guoxiang G; Louie, Gregory G; Kueider-Paisley, Alexandra A; Moseley, M Arthur MA; Thompson, J Will JW; St John Williams, Lisa L; Tenenbaum, Jessica D JD; Blach, Colette C; Baillie, Rebecca R; Han, Xianlin X; Bhattacharyya, Sudeepa S; Toledo, Jon B JB; Schafferer, Simon S; Klein, Sebastian S; Koal, Therese T; Risacher, Shannon L SL; Kling, Mitchel Allan MA; Motsinger-Reif, Alison A; Rotroff, Daniel M DM; Jack, John J; Hankemeier, Thomas T; Bennett, David A DA; De Jager, Philip L PL; Trojanowski, John Q JQ; Shaw, Leslie M LM; Weiner, Michael W MW; Doraiswamy, P Murali PM; van Duijn, Cornelia M CM; Saykin, Andrew J AJ; Kastenmüller, Gabi G; Kaddurah-Daouk, Rima R; ,
Publication Date: 2019-01

Variant appearance in text: rs9331896
PubMed Link: 30337151
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Alzheimer's Disease and Rheumatoid Arthritis: A Mendelian Randomization Study.

Frontiers In Neuroscience
Cai, Qixuan Q; Xin, Zhuoyuan Z; Zuo, Lin L; Li, Fan F; Liu, Bin B
Publication Date: 2018

Variant appearance in text: rs9331896
PubMed Link: 30258348
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Alzheimer's genetic risk is reduced in primary age-related tauopathy: a potential model of resistance?

Annals Of Clinical And Translational Neurology
McMillan, Corey T CT; Lee, Edward B EB; Jefferson-George, Kyra K; Naj, Adam A; Van Deerlin, Vivianna M VM; Trojanowski, John Q JQ; Wolk, David A DA
Publication Date: 2018-08

Variant appearance in text: rs9331896
PubMed Link: 30128317
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  • Main text
  • ACN3-5-927.pdf
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Probing the role of PPARγ in the regulation of late-onset Alzheimer's disease-associated genes.

Plos One
Barrera, Julio J; Subramanian, Shobana S; Chiba-Falek, Ornit O
Publication Date: 2018

Variant appearance in text: rs9331896
PubMed Link: 29723294
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  • pone.0196943.pdf
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Genetic variation in clusterin and risk of dementia and ischemic vascular disease in the general population: cohort studies and meta-analyses of 362,338 individuals.

Bmc Medicine
Nordestgaard, Liv Tybjærg LT; Tybjærg-Hansen, Anne A; Rasmussen, Katrine Laura KL; Nordestgaard, Børge G BG; Frikke-Schmidt, Ruth R
Publication Date: 2018-03-14

Variant appearance in text: rs9331896
PubMed Link: 29534716
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Assessment of the Genetic Architecture of Alzheimer's Disease Risk in Rate of Memory Decline.

Journal Of Alzheimer'S Disease : Jad
Del-Aguila, Jorge L JL; Fernández, Maria Victoria MV; Schindler, Suzanne S; Ibanez, Laura L; Deming, Yuetiva Y; Ma, Shengmei S; Saef, Ben B; Black, Kathleen K; Budde, John J; Norton, Joanne J; Chasse, Rachel R; , ; Harari, Oscar O; Goate, Alison A; Xiong, Chengjie C; Morris, John C JC; Cruchaga, Carlos C
Publication Date: 2018

Variant appearance in text: rs9331896
PubMed Link: 29480181
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Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer's disease pathogenesis.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Zhou, Xiaopu X; Chen, Yu Y; Mok, Kin Y KY; Zhao, Qianhua Q; Chen, Keliang K; Chen, Yuewen Y; Hardy, John J; Li, Yun Y; Fu, Amy K Y AKY; Guo, Qihao Q; Ip, Nancy Y NY; ,
Publication Date: 2018-02-20

Variant appearance in text: rs9331896
PubMed Link: 29432188
Variant Present in the following documents:
  • pnas.1715554115.sapp.pdf
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Unraveling the genes implicated in Alzheimer's disease.

Biomedical Reports
Giri, Mohan M; Shah, Abhilasha A; Upreti, Bibhuti B; Rai, Jayanti Chamling JC
Publication Date: 2017-08

Variant appearance in text: rs9331896
PubMed Link: 28781776
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Genome-wide significant, replicated and functional risk variants for Alzheimer's disease.

Journal Of Neural Transmission (Vienna, Austria : 1996)
Guo, Xiaoyun X; Qiu, Wenying W; Garcia-Milian, Rolando R; Lin, Xiandong X; Zhang, Yong Y; Cao, Yuping Y; Tan, Yunlong Y; Wang, Zhiren Z; Shi, Jing J; Wang, Jijun J; Liu, Dengtang D; Song, Lisheng L; Xu, Yifeng Y; Wang, Xiaoping X; Liu, Na N; Sun, Tao T; Zheng, Jianming J; Luo, Justine J; Zhang, Huihao H; Xu, Jianying J; Kang, Longli L; Ma, Chao C; Wang, Kesheng K; Luo, Xingguang X
Publication Date: 2017-11

Variant appearance in text: rs9331896
PubMed Link: 28770390
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