A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Jang, H Josh HJ; Hostetter, Galen G; MacFarlane, Alexander W AW; Madaj, Zachary Z; Ross, Eric A EA; Hinoue, Toshinori T; Kulchycki, Justin R JR; Burgos, Ryan S RS; Tafseer, Mahvish M; Alpaugh, R Katherine RK; Schwebel, Candice L CL; Kokate, Rutika R; Geynisman, Daniel M DM; Zibelman, Matthew R MR; Ghatalia, Pooja P; Nichols, Peter W PW; Chung, Woonbok W; Madzo, Jozef J; Hahn, Noah M NM; Quinn, David I DI; Issa, Jean-Pierre J JJ; Topper, Michael J MJ; Baylin, Stephen B SB; Shen, Hui H; Campbell, Kerry S KS; Jones, Peter A PA; Plimack, Elizabeth R ER
Response prediction in patients with gastric and esophagogastric adenocarcinoma under neoadjuvant chemotherapy using targeted gene expression analysis and next-generation sequencing in pre-therapeutic biopsies.
Journal Of Cancer Research And Clinical Oncology
Kleo, Karsten K; Jovanovic, Vladimir M VM; Arndold, Alexander A; Lehmann, Annika A; Lammert, Hedwig H; Berg, Erika E; Harloff, Hannah H; Treese, Christoph C; Hummel, Michael M; Daum, Severin S
The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes.
British Journal Of Cancer
Salas-Benito, Diego D; Conde, Enrique E; Tamayo-Uria, Ibon I; Mancheño, Uxua U; Elizalde, Edurne E; Garcia-Ros, David D; Aramendia, Jose M JM; Muruzabal, Juan C JC; Alcaide, Julia J; Guillen-Grima, Francisco F; Minguez, Jose A JA; Amores-Tirado, Jose J; Gonzalez-Martin, Antonio A; Sarobe, Pablo P; Lasarte, Juan J JJ; Ponz-Sarvise, Mariano M; De Andrea, Carlos E CE; Hervas-Stubbs, Sandra S
Publication Date: 2021-03
Variant appearance in text: NRG1: 866T>C; Met289Thr; rs10503929
NRG1, PIP4K2A, and HTR2C as Potential Candidate Biomarker Genes for Several Clinical Subphenotypes of Depression and Bipolar Disorder.
Frontiers In Genetics
Levchenko, Anastasia A; Vyalova, Natalia M NM; Nurgaliev, Timur T; Pozhidaev, Ivan V IV; Simutkin, German G GG; Bokhan, Nikolay A NA; Ivanova, Svetlana A SA
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Publication Date: 2019-10-09
Variant appearance in text: NRG1: M289T; rs10503929
A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Scientific Reports
Stringer, Brett W BW; Day, Bryan W BW; D'Souza, Rochelle C J RCJ; Jamieson, Paul R PR; Ensbey, Kathleen S KS; Bruce, Zara C ZC; Lim, Yi Chieh YC; Goasdoué, Kate K; Offenhäuser, Carolin C; Akgül, Seçkin S; Allan, Suzanne S; Robertson, Thomas T; Lucas, Peter P; Tollesson, Gert G; Campbell, Scott S; Winter, Craig C; Do, Hongdo H; Dobrovic, Alexander A; Inglis, Po-Ling PL; Jeffree, Rosalind L RL; Johns, Terrance G TG; Boyd, Andrew W AW
Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.
Cell Death & Disease
Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D
Prediction Analysis for Transition to Schizophrenia in Individuals at Clinical High Risk for Psychosis: The Relationship of DAO, DAOA, and NRG1 Variants with Negative Symptoms and Cognitive Deficits.
Frontiers In Psychiatry
Jagannath, Vinita V; Theodoridou, Anastasia A; Gerstenberg, Miriam M; Franscini, Maurizia M; Heekeren, Karsten K; Correll, Christoph U CU; Rössler, Wulf W; Grünblatt, Edna E; Walitza, Susanne S
Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.
The Journal Of Pathology
Maguire, Sarah L SL; Peck, Barrie B; Wai, Patty T PT; Campbell, James J; Barker, Holly H; Gulati, Aditi A; Daley, Frances F; Vyse, Simon S; Huang, Paul P; Lord, Christopher J CJ; Farnie, Gillian G; Brennan, Keith K; Natrajan, Rachael R
Publication Date: 2016-11
Variant appearance in text: NRG1: M289T; rs10503929
Hierarchical Classes Analysis (HICLAS): A novel data reduction method to examine associations between biallelic SNPs and perceptual organization phenotypes in schizophrenia.
Schizophrenia Research. Cognition
Joseph, Jamie J; Gara, Michael A MA; Silverstein, Steven M SM
Investigation of gene effects and epistatic interactions between Akt1 and neuregulin 1 in the regulation of behavioral phenotypes and social functions in genetic mouse models of schizophrenia.
Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Publication Date: 2014
Variant appearance in text: NRG1: M289T; rs10503929
Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium.
Human Genetics
Li, Qing Q; Wojciechowski, Robert R; Simpson, Claire L CL; Hysi, Pirro G PG; Verhoeven, Virginie J M VJ; Ikram, Mohammad Kamran MK; Höhn, René R; Vitart, Veronique V; Hewitt, Alex W AW; Oexle, Konrad K; Mäkelä, Kari-Matti KM; MacGregor, Stuart S; Pirastu, Mario M; Fan, Qiao Q; Cheng, Ching-Yu CY; St Pourcain, Beaté B; McMahon, George G; Kemp, John P JP; Northstone, Kate K; Rahi, Jugnoo S JS; Cumberland, Phillippa M PM; Martin, Nicholas G NG; Sanfilippo, Paul G PG; Lu, Yi Y; Wang, Ya Xing YX; Hayward, Caroline C; Polašek, Ozren O; Campbell, Harry H; Bencic, Goran G; Wright, Alan F AF; Wedenoja, Juho J; Zeller, Tanja T; Schillert, Arne A; Mirshahi, Alireza A; Lackner, Karl K; Yip, Shea Ping SP; Yap, Maurice K H MK; Ried, Janina S JS; Gieger, Christian C; Murgia, Federico F; Wilson, James F JF; Fleck, Brian B; Yazar, Seyhan S; Vingerling, Johannes R JR; Hofman, Albert A; Uitterlinden, André A; Rivadeneira, Fernando F; Amin, Najaf N; Karssen, Lennart L; Oostra, Ben A BA; Zhou, Xin X; Teo, Yik-Ying YY; Tai, E Shyong ES; Vithana, Eranga E; Barathi, Veluchamy V; Zheng, Yingfeng Y; Siantar, Rosalynn Grace RG; Neelam, Kumari K; Shin, Youchan Y; Lam, Janice J; Yonova-Doing, Ekaterina E; Venturini, Cristina C; Hosseini, S Mohsen SM; Wong, Hoi-Suen HS; Lehtimäki, Terho T; Kähönen, Mika M; Raitakari, Olli O; Timpson, Nicholas J NJ; Evans, David M DM; Khor, Chiea-Chuen CC; Aung, Tin T; Young, Terri L TL; Mitchell, Paul P; Klein, Barbara B; van Duijn, Cornelia M CM; Meitinger, Thomas T; Jonas, Jost B JB; Baird, Paul N PN; Mackey, David A DA; Wong, Tien Yin TY; Saw, Seang-Mei SM; Pärssinen, Olavi O; Stambolian, Dwight D; Hammond, Christopher J CJ; Klaver, Caroline C W CC; Williams, Cathy C; Paterson, Andrew D AD; Bailey-Wilson, Joan E JE; Guggenheim, Jeremy A JA; ,
Analysis of schizophrenia-related genes and electrophysiological measures reveals ZNF804A association with amplitude of P300b elicited by novel sounds.
Translational Psychiatry
Del Re, E C EC; Bergen, S E SE; Mesholam-Gately, R I RI; Niznikiewicz, M A MA; Goldstein, J M JM; Woo, T U TU; Shenton, M E ME; Seidman, L J LJ; McCarley, R W RW; Petryshen, T L TL
Comprehensive analysis of NRG1 common and rare variants in Hirschsprung patients.
Plos One
Luzón-Toro, Berta B; Torroglosa, Ana A; Núñez-Torres, Rocío R; Enguix-Riego, María Valle MV; Fernández, Raquel María RM; de Agustín, Juan Carlos JC; Antiñolo, Guillermo G; Borrego, Salud S
Genetic associations between neuregulin-1 SNPs and neurocognitive function in multigenerational, multiplex schizophrenia families.
Psychiatric Genetics
Yokley, Jessica L JL; Prasad, Konasale M KM; Chowdari, Kodavali V KV; Talkowski, Michael E ME; Wood, Joel J; Gur, Ruben C RC; Gur, Raquel E RE; Almasy, Laura L; Nimgaonkar, Vishwajit L VL; Pogue-Geile, Michael F MF
Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls.
Archives Of General Psychiatry
Nicodemus, Kristin K KK; Law, Amanda J AJ; Radulescu, Eugenia E; Luna, Augustin A; Kolachana, Bhaskar B; Vakkalanka, Radhakrishna R; Rujescu, Dan D; Giegling, Ina I; Straub, Richard E RE; McGee, Kate K; Gold, Bert B; Dean, Michael M; Muglia, Pierandrea P; Callicott, Joseph H JH; Tan, Hao-Yang HY; Weinberger, Daniel R DR