Publications:

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Genetic architecture of human plasma lipidome and its link to cardiovascular disease.

Nature Communications

R Tabassum, JT Rämö, P Ripatti, JT Koskela, M Kurki, J Karjalainen, P Palta, S Hassan, J Nunez-Fontarnau, TTJ Kiiskinen, S Söderlund, N Matikainen, MJ Gerl, MA Surma, C Klose, NO Stitziel, H Laivuori, AS Havulinna, SK Service, V Salomaa, M Pirinen, , M Jauhiainen, MJ Daly, NB Freimer, A Palotie, MR Taskinen, K Simons, S Ripatti

Publication Date: 2019-09-24

Variant appearance in text: rs4149268

PubMed Link: 31551469

Variant Present in the following documents:

• 41467_2019_11954_MOESM13_ESM.xlsx

View BVdb publication page

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The transferability of lipid loci across African, Asian and European cohorts.

Nature Communications

K Kuchenbaecker, N Telkar, T Reiker, RG Walters, K Lin, A Eriksson, D Gurdasani, A Gilly, L Southam, E Tsafantakis, M Karaleftheri, J Seeley, A Kamali, G Asiki, IY Millwood, M Holmes, H Du, Y Guo, M Kumari, G Dedoussis, L Li, Z Chen, MS Sandhu, E Zeggini,

Publication Date: 2019-09-24

Variant appearance in text: rs4149268

PubMed Link: 31551420

Variant Present in the following documents:

• 41467_2019_12026_MOESM1_ESM.pdf

View BVdb publication page

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A Birth Cohort Study on the Genetic Modification of the Association of Prenatal Methylmercury With Child Cognitive Development.

American Journal Of Epidemiology

J Julvez, G Davey Smith, S Ring, P Grandjean

Publication Date: 2019-10-01

Variant appearance in text: rs4149268

PubMed Link: 31241132

Variant Present in the following documents:

• Main text
• kwz156_julvez_web_material_final.pdf

View BVdb publication page

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Allele-specific enhancers mediate associations between LCAT and ABCA1 polymorphisms and HDL metabolism.

Plos One

AD Howard, X Wang, M Prasad, AD Sahu, R Aniba, M Miller, S Hannenhalli, YC Chang

Publication Date: 2019

Variant appearance in text: rs4149268

PubMed Link: 31039173

Variant Present in the following documents:

• Main text

View BVdb publication page

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Vitamin E Metabolic Effects and Genetic Variants: A Challenge for Precision Nutrition in Obesity and Associated Disturbances.

Nutrients

S Galmés, F Serra, A Palou

Publication Date: 2018-12-04

Variant appearance in text: rs4149268

PubMed Link: 30518135

Variant Present in the following documents:

• Main text

View BVdb publication page

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Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.

Plos Genetics

JP Davis, JR Huyghe, AE Locke, AU Jackson, X Sim, HM Stringham, TM Teslovich, RP Welch, C Fuchsberger, N Narisu, PS Chines, AJ Kangas, P Soininen, M Ala-Korpela, J Kuusisto, FS Collins, M Laakso, M Boehnke, KL Mohlke

Publication Date: 2017-10

Variant appearance in text: rs4149268

PubMed Link: 29084231

Variant Present in the following documents:

• pgen.1007079.s010.xlsx
• pgen.1007079.s011.xlsx

View BVdb publication page

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Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.

Nature Genetics

X Lu, GM Peloso, DJ Liu, Y Wu, H Zhang, W Zhou, J Li, CS Tang, R Dorajoo, H Li, J Long, X Guo, M Xu, CN Spracklen, Y Chen, X Liu, Y Zhang, CC Khor, J Liu, L Sun, L Wang, YT Gao, Y Hu, K Yu, Y Wang, CYY Cheung, F Wang, J Huang, Q Fan, Q Cai, S Chen, J Shi, X Yang, W Zhao, WH Sheu, SS Cherny, M He, AB Feranil, LS Adair, P Gordon-Larsen, S Du, R Varma, YI Chen, XO Shu, KSL Lam, TY Wong, SK Ganesh, Z Mo, K Hveem, LG Fritsche, JB Nielsen, HF Tse, Y Huo, CY Cheng, YE Chen, W Zheng, ES Tai, W Gao, X Lin, W Huang, G Abecasis, , S Kathiresan, KL Mohlke, T Wu, PC Sham, D Gu, CJ Willer

Publication Date: 2017-12

Variant appearance in text: rs4149268

PubMed Link: 29083407

Variant Present in the following documents:

• NIHMS909133-supplement-2.xlsx

View BVdb publication page

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Data to genetic risk assessment on high-density cholesterol level associated polymorphisms in Hungarian general and Roma populations.

Data In Brief

P Pikó, S Fiatal, Z Kósa, J Sándor, R Ádány

Publication Date: 2017-10

Variant appearance in text: rs4149268

PubMed Link: 28795114

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.

Lipids In Health And Disease

CS Paththinige, ND Sirisena, V Dissanayake

Publication Date: 2017-06-02

Variant appearance in text: rs4149268

PubMed Link: 28577571

Variant Present in the following documents:

• 12944_2017_488_MOESM1_ESM.xlsx
• aaaaaMain text

View BVdb publication page

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Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.

Journal Of Cellular And Molecular Medicine

Y Zhu, D Zhang, D Zhou, Z Li, Z Li, L Fang, M Yang, Z Shan, H Li, J Chen, X Zhou, W Ye, S Yu, H Li, L Cai, C Liu, J Zhang, L Wang, Y Lai, L Ruan, Z Sun, S Zhang, H Wang, Y Liu, Y Xu, J Ling, C Xu, Y Zhang, D Lv, Z Yuan, J Zhang, Y Zhang, Y Shi, M Lai

Publication Date: 2017-06

Variant appearance in text: rs4149268

PubMed Link: 28371326

Variant Present in the following documents:

• JCMM-21-1106-s002.xlsx

View BVdb publication page

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Evaluation of transethnic fine mapping with population-specific and cosmopolitan imputation reference panels in diverse Asian populations.

European Journal Of Human Genetics : Ejhg

X Wang, CY Cheng, J Liao, X Sim, J Liu, KS Chia, ES Tai, P Little, CC Khor, T Aung, TY Wong, YY Teo

Publication Date: 2016-04

Variant appearance in text: rs4149268

PubMed Link: 26130488

Variant Present in the following documents:

• ejhg2015150x4.xls

View BVdb publication page

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Apolipoprotein E and protection against hepatitis E viral infection in American non-Hispanic blacks.

Hepatology (Baltimore, Md.)

L Zhang, A Yesupriya, MH Chang, E Teshale, CG Teo

Publication Date: 2015-11

Variant appearance in text: rs4149268

PubMed Link: 26096528

Variant Present in the following documents:

• NIHMS1043972-supplement-Supplemental.pdf

View BVdb publication page

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Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study.

Plos Genetics

MA Hall, A Verma, KD Brown-Gentry, R Goodloe, J Boston, S Wilson, B McClellan, C Sutcliffe, HH Dilks, NB Gillani, H Jin, P Mayo, M Allen, N Schnetz-Boutaud, DC Crawford, MD Ritchie, SA Pendergrass

Publication Date: 2014-12

Variant appearance in text: rs4149268

PubMed Link: 25474351

Variant Present in the following documents:

• pgen.1004678.s007.xlsx

View BVdb publication page

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Genetic loci associated with changes in lipid levels leading to constitution-based discrepancy in Koreans.

Bmc Complementary And Alternative Medicine

SK Chung, H Yu, AY Park, JY Kim, S Cha

Publication Date: 2014-07-09

Variant appearance in text: rs4149268

PubMed Link: 25005712

Variant Present in the following documents:

• 1472-6882-14-230-S1.xls

View BVdb publication page

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Genetic predisposition scores for dyslipidaemia influence plasma lipid concentrations at baseline, but not the changes after controlled intake of n-3 polyunsaturated fatty acids.

Genes & Nutrition

A AlSaleh, Z Maniou, FJ Lewis, WL Hall, TA Sanders, SD O'Dell

Publication Date: 2014-07

Variant appearance in text: rs4149268

PubMed Link: 24890013

Variant Present in the following documents:

• 12263_2014_412_MOESM1_ESM.pdf
• 12263_2014_412_MOESM2_ESM.pdf
• 12263_2014_412_MOESM3_ESM.pdf
• 12263_2014_412_MOESM4_ESM.pdf

View BVdb publication page

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Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study.

Circulation. Cardiovascular Genetics

JM Kocarnik, SA Pendergrass, CL Carty, JS Pankow, FR Schumacher, I Cheng, P Durda, JL Ambite, E Deelman, NR Cook, S Liu, J Wactawski-Wende, C Hutter, K Brown-Gentry, S Wilson, LG Best, N Pankratz, CP Hong, SA Cole, VS Voruganti, P Bůžkova, NW Jorgensen, NS Jenny, LR Wilkens, CA Haiman, LN Kolonel, A Lacroix, K North, R Jackson, L Le Marchand, LA Hindorff, DC Crawford, M Gross, U Peters

Publication Date: 2014-04

Variant appearance in text: rs4149268

PubMed Link: 24622110

Variant Present in the following documents:

• NIHMS575195-supplement-000173_-_Supplemental_Material.pdf

View BVdb publication page

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Lipid trait-associated genetic variation is associated with gallstone disease in the diverse Third National Health and Nutrition Examination Survey (NHANES III).

Bmc Medical Genetics

R Goodloe, K Brown-Gentry, NB Gillani, H Jin, P Mayo, M Allen, B McClellan, J Boston, C Sutcliffe, N Schnetz-Boutaud, HH Dilks, DC Crawford

Publication Date: 2013-11-21

Variant appearance in text: rs4149268

PubMed Link: 24256507

Variant Present in the following documents:

• 1471-2350-14-120-S1.doc
• aaaaaMain text

View BVdb publication page

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Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations.

Cerebrovascular Diseases (Basel, Switzerland)

SY Chou, JM Shulman, BT Keenan, EA Secor, AS Buchman, J Schneider, DA Bennett, PL De Jager

Publication Date: 2013

Variant appearance in text: rs4149268

PubMed Link: 24135527

Variant Present in the following documents:

• NIHMS527173-supplement-01.pdf

View BVdb publication page

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No evidence of interaction between known lipid-associated genetic variants and smoking in the multi-ethnic PAGE population.

Human Genetics

L Dumitrescu, CL Carty, N Franceschini, LA Hindorff, SA Cole, P Bůžková, FR Schumacher, CB Eaton, RJ Goodloe, DJ Duggan, J Haessler, B Cochran, BE Henderson, I Cheng, KC Johnson, CS Carlson, SA Love, K Brown-Gentry, AQ Nato, M Quibrera, RV Shohet, JL Ambite, LR Wilkens, L Le Marchand, CA Haiman, S Buyske, C Kooperberg, KE North, M Fornage, DC Crawford

Publication Date: 2013-12

Variant appearance in text: rs4149268

PubMed Link: 24100633

Variant Present in the following documents:

• NIHMS530028-supplement-439_2013_1375_MOESM1_ESM.docx

View BVdb publication page

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Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study.

Plos Biology

CS Carlson, TC Matise, KE North, CA Haiman, MD Fesinmeyer, S Buyske, FR Schumacher, U Peters, N Franceschini, MD Ritchie, DJ Duggan, KL Spencer, L Dumitrescu, CB Eaton, F Thomas, A Young, C Carty, G Heiss, L Le Marchand, DC Crawford, LA Hindorff, CL Kooperberg,

Publication Date: 2013-09

Variant appearance in text: rs4149268

PubMed Link: 24068893

Variant Present in the following documents:

• pbio.1001661.s003.xlsx
• pbio.1001661.s004.xlsx

View BVdb publication page

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Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study.

Bmc Genetics

KC Taylor, CL Carty, L Dumitrescu, P Bůžková, SA Cole, L Hindorff, FR Schumacher, LR Wilkens, RV Shohet, PM Quibrera, KC Johnson, BE Henderson, J Haessler, N Franceschini, CB Eaton, DJ Duggan, B Cochran, I Cheng, CS Carlson, K Brown-Gentry, G Anderson, JL Ambite, C Haiman, L Le Marchand, C Kooperberg, DC Crawford, S Buyske, KE North, M Fornage,

Publication Date: 2013-05-01

Variant appearance in text: rs4149268

PubMed Link: 23634756

Variant Present in the following documents:

• 1471-2156-14-33-S1.pdf

View BVdb publication page

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Genetic variants from lipid-related pathways and risk for incident myocardial infarction.

Plos One

C Song, NL Pedersen, CA Reynolds, M Sabater-Lleal, S Kanoni, C Willenborg, , AC Syvänen, H Watkins, A Hamsten, JA Prince, E Ingelsson

Publication Date: 2013

Variant appearance in text: rs4149268

PubMed Link: 23555974

Variant Present in the following documents:

• pone.0060454.s001.pdf

View BVdb publication page

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Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network.

Plos Genetics

SA Pendergrass, K Brown-Gentry, S Dudek, A Frase, ES Torstenson, R Goodloe, JL Ambite, CL Avery, S Buyske, P Bůžková, E Deelman, MD Fesinmeyer, CA Haiman, G Heiss, LA Hindorff, CN Hsu, RD Jackson, C Kooperberg, L Le Marchand, Y Lin, TC Matise, KR Monroe, L Moreland, SL Park, A Reiner, R Wallace, LR Wilkens, DC Crawford, MD Ritchie

Publication Date: 2013

Variant appearance in text: rs4149268

PubMed Link: 23382687

Variant Present in the following documents:

• pgen.1003087.s001.xlsx

View BVdb publication page

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Association of cardiovascular and metabolic disease genes with psoriasis.

The Journal Of Investigative Dermatology

Y Lu, H Chen, P Nikamo, H Qi Low, C Helms, M Seielstad, J Liu, AM Bowcock, M Stahle, W Liao

Publication Date: 2013-03

Variant appearance in text: rs4149268

PubMed Link: 23190900

Variant Present in the following documents:

• NIHMS404713-supplement-01.pdf

View BVdb publication page

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Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

American Journal Of Human Genetics

FW Asselbergs, Y Guo, EP van Iperen, S Sivapalaratnam, V Tragante, MB Lanktree, LA Lange, B Almoguera, YE Appelman, J Barnard, J Baumert, AL Beitelshees, TR Bhangale, YD Chen, TR Gaunt, Y Gong, JC Hopewell, T Johnson, ME Kleber, TY Langaee, M Li, YR Li, K Liu, CW McDonough, MF Meijs, RP Middelberg, K Musunuru, CP Nelson, JR O'Connell, S Padmanabhan, JS Pankow, N Pankratz, S Rafelt, R Rajagopalan, SP Romaine, NJ Schork, J Shaffer, H Shen, EN Smith, SE Tischfield, PJ van der Most, JV van Vliet-Ostaptchouk, N Verweij, KA Volcik, L Zhang, KR Bailey, KM Bailey, F Bauer, JM Boer, PS Braund, A Burt, PR Burton, SG Buxbaum, W Chen, RM Cooper-Dehoff, LA Cupples, JS deJong, C Delles, D Duggan, M Fornage, CE Furlong, N Glazer, JG Gums, C Hastie, MV Holmes, T Illig, SA Kirkland, M Kivimaki, R Klein, BE Klein, C Kooperberg, K Kottke-Marchant, M Kumari, AZ LaCroix, L Mallela, G Murugesan, J Ordovas, WH Ouwehand, WS Post, R Saxena, H Scharnagl, PJ Schreiner, T Shah, DC Shields, D Shimbo, SR Srinivasan, RP Stolk, DI Swerdlow, HA Taylor, EJ Topol, E Toskala, JL van Pelt, J van Setten, S Yusuf, JC Whittaker, AH Zwinderman, , SS Anand, AJ Balmforth, GS Berenson, CR Bezzina, BO Boehm, E Boerwinkle, JP Casas, MJ Caulfield, R Clarke, JM Connell, KJ Cruickshanks, KW Davidson, IN Day, PI de Bakker, PA Doevendans, AF Dominiczak, AS Hall, CA Hartman, C Hengstenberg, HL Hillege, MH Hofker, SE Humphries, GP Jarvik, JA Johnson, BM Kaess, S Kathiresan, W Koenig, DA Lawlor, W März, O Melander, BD Mitchell, GW Montgomery, PB Munroe, SS Murray, SJ Newhouse, NC Onland-Moret, N Poulter, B Psaty, S Redline, SS Rich, JI Rotter, H Schunkert, P Sever, AR Shuldiner, RL Silverstein, A Stanton, B Thorand, MD Trip, MY Tsai, P van der Harst, E van der Schoot, YT van der Schouw, WM Verschuren, H Watkins, AA Wilde, BH Wolffenbuttel, JB Whitfield, GK Hovingh, CM Ballantyne, C Wijmenga, MP Reilly, NG Martin, JG Wilson, DJ Rader, NJ Samani, AP Reiner, RA Hegele, JJ Kastelein, AD Hingorani, PJ Talmud, H Hakonarson, CC Elbers, BJ Keating, F Drenos

Publication Date: 2012-11-02

Variant appearance in text: rs4149268

PubMed Link: 23063622

Variant Present in the following documents:

• mmc4.xls
• mmc7.xls

View BVdb publication page

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Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals.

Plos One

F Takeuchi, M Isono, T Katsuya, M Yokota, K Yamamoto, T Nabika, K Shimokawa, E Nakashima, T Sugiyama, H Rakugi, S Yamaguchi, T Ogihara, Y Yamori, N Kato

Publication Date: 2012

Variant appearance in text: rs4149268

PubMed Link: 23050023

Variant Present in the following documents:

• pone.0046385.s002.xls
• pone.0046385.s003.xls
• pone.0046385.s004.xls
• pone.0046385.s005.xls

View BVdb publication page

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Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases.

Bmc Medical Genetics

S Huhn, M Bevier, A Rudolph, B Pardini, A Naccarati, R Hein, M Hoffmeister, L Vodickova, J Novotny, H Brenner, J Chang-Claude, K Hemminki, P Vodicka, A Försti

Publication Date: 2012-10-05

Variant appearance in text: rs4149268

PubMed Link: 23036011

Variant Present in the following documents:

• 1471-2350-13-94-S1.pdf
• aaaaaMain text

View BVdb publication page

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Hypothesis-based analysis of gene-gene interactions and risk of myocardial infarction.

Plos One

G Lucas, C Lluís-Ganella, I Subirana, MD Musameh, JR Gonzalez, CP Nelson, M Sentí, , , SM Schwartz, D Siscovick, CJ O'Donnell, O Melander, V Salomaa, S Purcell, D Altshuler, NJ Samani, S Kathiresan, R Elosua

Publication Date: 2012

Variant appearance in text: rs4149268

PubMed Link: 22876292

Variant Present in the following documents:

• pone.0041730.s001.pdf

View BVdb publication page

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Evolutionary responses to a constructed niche: ancient Mesoamericans as a model of gene-culture coevolution.

Plos One

T Hünemeier, CE Amorim, S Azevedo, V Contini, V Acuña-Alonzo, F Rothhammer, JM Dugoujon, S Mazières, R Barrantes, MT Villarreal-Molina, VR Paixão-Côrtes, FM Salzano, S Canizales-Quinteros, A Ruiz-Linares, MC Bortolini

Publication Date: 2012

Variant appearance in text: rs4149268

PubMed Link: 22768049

Variant Present in the following documents:

• Main text
• pone.0038862.s004.docx

View BVdb publication page

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Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain.

Neurobiology Of Disease

DG Hernandez, MA Nalls, M Moore, S Chong, A Dillman, D Trabzuni, JR Gibbs, M Ryten, S Arepalli, ME Weale, AB Zonderman, J Troncoso, R O'Brien, R Walker, C Smith, S Bandinelli, BJ Traynor, J Hardy, AB Singleton, MR Cookson

Publication Date: 2012-07

Variant appearance in text: rs4149268

PubMed Link: 22433082

Variant Present in the following documents:

• mmc1.xls

View BVdb publication page

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A genome-wide scan for common variants affecting the rate of age-related cognitive decline.

Neurobiology Of Aging

PL De Jager, JM Shulman, LB Chibnik, BT Keenan, T Raj, RS Wilson, L Yu, SE Leurgans, D Tran, C Aubin, CD Anderson, A Biffi, JJ Corneveaux, MJ Huentelman, , J Rosand, MJ Daly, AJ Myers, EM Reiman, DA Bennett, DA Evans

Publication Date: 2012-05

Variant appearance in text: rs4149268

PubMed Link: 22054870

Variant Present in the following documents:

• NIHMS328602-supplement-01.doc

View BVdb publication page

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Implications of discoveries from genome-wide association studies in current cardiovascular practice.

World Journal Of Cardiology

P Jeemon, K Pettigrew, C Sainsbury, D Prabhakaran, S Padmanabhan

Publication Date: 2011-07-26

Variant appearance in text: rs4149268

PubMed Link: 21860704

Variant Present in the following documents:

• Main text

View BVdb publication page

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Validation of candidate genes associated with cardiovascular risk factors in psychiatric patients.

Progress In Neuro-Psychopharmacology & Biological Psychiatry

A Windemuth, J de Leon, JW Goethe, HI Schwartz, S Woolley, M Susce, M Kocherla, K Bogaard, TR Holford, RL Seip, G Ruaño

Publication Date: 2012-03-30

Variant appearance in text: rs4149268

PubMed Link: 21851846

Variant Present in the following documents:

• Main text

View BVdb publication page

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Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA.

Plos Genetics

RS Fehrmann, RC Jansen, JH Veldink, HJ Westra, D Arends, MJ Bonder, J Fu, P Deelen, HJ Groen, A Smolonska, RK Weersma, RM Hofstra, WA Buurman, S Rensen, MG Wolfs, M Platteel, A Zhernakova, CC Elbers, EM Festen, G Trynka, MH Hofker, CG Saris, RA Ophoff, LH van den Berg, DA van Heel, C Wijmenga, GJ Te Meerman, L Franke

Publication Date: 2011-08

Variant appearance in text: rs4149268

PubMed Link: 21829388

Variant Present in the following documents:

• pgen.1002197.s016.xls

View BVdb publication page

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Evidence for age as a modifier of genetic associations for lipid levels.

Annals Of Human Genetics

L Dumitrescu, K Brown-Gentry, R Goodloe, K Glenn, W Yang, N Kornegay, CH Pui, MV Relling, DC Crawford

Publication Date: 2011-09

Variant appearance in text: rs4149268

PubMed Link: 21777205

Variant Present in the following documents:

• NIHMS304382-supplement-Supp_Table_S1-S4.doc

View BVdb publication page

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Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study.

Plos Genetics

L Dumitrescu, CL Carty, K Taylor, FR Schumacher, LA Hindorff, JL Ambite, G Anderson, LG Best, K Brown-Gentry, P Bůžková, CS Carlson, B Cochran, SA Cole, RB Devereux, D Duggan, CB Eaton, M Fornage, N Franceschini, J Haessler, BV Howard, KC Johnson, S Laston, LN Kolonel, ET Lee, JW MacCluer, TA Manolio, SA Pendergrass, M Quibrera, RV Shohet, LR Wilkens, CA Haiman, L Le Marchand, S Buyske, C Kooperberg, KE North, DC Crawford

Publication Date: 2011-06

Variant appearance in text: rs4149268

PubMed Link: 21738485

Variant Present in the following documents:

• Main text
• pgen.1002138.s015.doc

View BVdb publication page

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Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

Plos Genetics

G Lettre, CD Palmer, T Young, KG Ejebe, H Allayee, EJ Benjamin, F Bennett, DW Bowden, A Chakravarti, A Dreisbach, DN Farlow, AR Folsom, M Fornage, T Forrester, E Fox, CA Haiman, J Hartiala, TB Harris, SL Hazen, SR Heckbert, BE Henderson, JN Hirschhorn, BJ Keating, SB Kritchevsky, E Larkin, M Li, ME Rudock, CA McKenzie, JB Meigs, YA Meng, TH Mosley, AB Newman, CH Newton-Cheh, DN Paltoo, GJ Papanicolaou, N Patterson, WS Post, BM Psaty, AN Qasim, L Qu, DJ Rader, S Redline, MP Reilly, AP Reiner, SS Rich, JI Rotter, Y Liu, P Shrader, DS Siscovick, WH Tang, HA Taylor, RP Tracy, RS Vasan, KM Waters, R Wilks, JG Wilson, RR Fabsitz, SB Gabriel, S Kathiresan, E Boerwinkle

Publication Date: 2011-02-10

Variant appearance in text: rs4149268

PubMed Link: 21347282

Variant Present in the following documents:

• pgen.1001300.s016.doc
• pgen.1001300.s017.doc

View BVdb publication page

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Dense genotyping of candidate gene loci identifies variants associated with high-density lipoprotein cholesterol.

Circulation. Cardiovascular Genetics

AC Edmondson, PS Braund, IM Stylianou, AV Khera, CP Nelson, ML Wolfe, SL Derohannessian, BJ Keating, L Qu, J He, MD Tobin, M Tomaszewski, J Baumert, N Klopp, A Döring, B Thorand, M Li, MP Reilly, W Koenig, NJ Samani, DJ Rader

Publication Date: 2011-04

Variant appearance in text: rs4149268

PubMed Link: 21303902

Variant Present in the following documents:

• NIHMS280051-supplement-1.pdf

View BVdb publication page

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Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review.

American Journal Of Epidemiology

OA Panagiotou, E Evangelou, JP Ioannidis

Publication Date: 2010-10-15

Variant appearance in text: rs4149268

PubMed Link: 20876667

Variant Present in the following documents:

• Main text

View BVdb publication page

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Joint effects of common genetic variants from multiple genes and pathways on the risk of premature coronary artery disease.

American Heart Journal

JL Anderson, BD Horne, NJ Camp, JB Muhlestein, PN Hopkins, LA Cannon-Albright, CP Mower, JJ Park, JL Clarke, ZP Nicholas, JT McKinney, JF Carlquist

Publication Date: 2010-08

Variant appearance in text: rs4149268

PubMed Link: 20691829

Variant Present in the following documents:

• NIHMS209707-supplement-1.doc

View BVdb publication page

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Genetic causes of high and low serum HDL-cholesterol.

Journal Of Lipid Research

D Weissglas-Volkov, P Pajukanta

Publication Date: 2010-08

Variant appearance in text: rs4149268

PubMed Link: 20421590

Variant Present in the following documents:

• Main text

View BVdb publication page

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The genetics of obesity and the metabolic syndrome.

Endocrine, Metabolic & Immune Disorders Drug Targets

KL Monda, KE North, SC Hunt, DC Rao, MA Province, AT Kraja

Publication Date: 2010-06

Variant appearance in text: rs4149268

PubMed Link: 20406164

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genome-wide association of lipid-lowering response to statins in combined study populations.

Plos One

MJ Barber, LM Mangravite, CL Hyde, DI Chasman, JD Smith, CA McCarty, X Li, RA Wilke, MJ Rieder, PT Williams, PM Ridker, A Chatterjee, JI Rotter, DA Nickerson, M Stephens, RM Krauss

Publication Date: 2010-03-22

Variant appearance in text: rs4149268

PubMed Link: 20339536

Variant Present in the following documents:

• pone.0009763.s008.xls

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Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication.

Circulation. Cardiovascular Genetics

DI Chasman, G Paré, RY Zee, AN Parker, NR Cook, JE Buring, DJ Kwiatkowski, LM Rose, JD Smith, PT Williams, MJ Rieder, JI Rotter, DA Nickerson, RM Krauss, JP Miletich, PM Ridker

Publication Date: 2008-10

Variant appearance in text: rs4149268

PubMed Link: 19802338

Variant Present in the following documents:

• Main text

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A survey of ABCA1 sequence variation confirms association with dementia.

Human Mutation

CA Reynolds, MG Hong, UK Eriksson, K Blennow, AM Bennet, B Johansson, B Malmberg, S Berg, F Wiklund, M Gatz, NL Pedersen, JA Prince

Publication Date: 2009-09

Variant appearance in text: rs4149268

PubMed Link: 19606474

Variant Present in the following documents:

• Main text
• NIHMS143316-supplement-Supp_data_01.pdf

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Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.

European Heart Journal

A Murray, C Cluett, S Bandinelli, AM Corsi, L Ferrucci, J Guralnik, A Singleton, T Frayling, D Melzer

Publication Date: 2009-07

Variant appearance in text: rs4149268

PubMed Link: 19435741

Variant Present in the following documents:

• Main text

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Genome-wide linkage scan for plasma high density lipoprotein cholesterol, apolipoprotein A-1 and triglyceride variation among American Indian populations: the Strong Heart Family Study.

Journal Of Medical Genetics

X Li, KL Monda, HH Göring, K Haack, SA Cole, VP Diego, L Almasy, S Laston, BV Howard, NM Shara, ET Lee, LG Best, RR Fabsitz, JW MacCluer, KE North

Publication Date: 2009-07

Variant appearance in text: rs4149268

PubMed Link: 19429595

Variant Present in the following documents:

• Main text
• NIHMS312482-supplement-Supplemental_Tables.doc

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Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.

American Journal Of Human Genetics

L Ferrucci, JR Perry, A Matteini, M Perola, T Tanaka, K Silander, N Rice, D Melzer, A Murray, C Cluett, LP Fried, D Albanes, AM Corsi, A Cherubini, J Guralnik, S Bandinelli, A Singleton, J Virtamo, J Walston, RD Semba, TM Frayling

Publication Date: 2009-02

Variant appearance in text: rs4149268

PubMed Link: 19185284

Variant Present in the following documents:

• Main text

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Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.

Nature Genetics

C Sabatti, SK Service, AL Hartikainen, A Pouta, S Ripatti, J Brodsky, CG Jones, NA Zaitlen, T Varilo, M Kaakinen, U Sovio, A Ruokonen, J Laitinen, E Jakkula, L Coin, C Hoggart, A Collins, H Turunen, S Gabriel, P Elliot, MI McCarthy, MJ Daly, MR Järvelin, NB Freimer, L Peltonen

Publication Date: 2009-01

Variant appearance in text: rs4149268

PubMed Link: 19060910

Variant Present in the following documents:

• Main text

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Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.

Experimental Gerontology

E Boes, S Coassin, B Kollerits, IM Heid, F Kronenberg

Publication Date: 2009-03

Variant appearance in text: rs4149268

PubMed Link: 19041386

Variant Present in the following documents:

• Main text

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Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.

Human Molecular Genetics

KL Mohlke, M Boehnke, GR Abecasis

Publication Date: 2008-10-15

Variant appearance in text: rs4149268

PubMed Link: 18852197

Variant Present in the following documents:

• Main text

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Newly identified loci that influence lipid concentrations and risk of coronary artery disease.

Nature Genetics

CJ Willer, S Sanna, AU Jackson, A Scuteri, LL Bonnycastle, R Clarke, SC Heath, NJ Timpson, SS Najjar, HM Stringham, J Strait, WL Duren, A Maschio, F Busonero, A Mulas, G Albai, AJ Swift, MA Morken, N Narisu, D Bennett, S Parish, H Shen, P Galan, P Meneton, S Hercberg, D Zelenika, WM Chen, Y Li, LJ Scott, PA Scheet, J Sundvall, RM Watanabe, R Nagaraja, S Ebrahim, DA Lawlor, Y Ben-Shlomo, G Davey-Smith, AR Shuldiner, R Collins, RN Bergman, M Uda, J Tuomilehto, A Cao, FS Collins, E Lakatta, GM Lathrop, M Boehnke, D Schlessinger, KL Mohlke, GR Abecasis

Publication Date: 2008-02

Variant appearance in text: rs4149268

PubMed Link: 18193043

Variant Present in the following documents:

• Main text
• NIHMS836655-supplement-Supplementary_Material.pdf

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Alternative transcript annotations:

Transcript	cDNA	Protein	Consequence	Exon	Intron
ENST00000374733.1	c.-20-371G>A	-	intron_variant	-	2/4
ENST00000374736.3	c.161-371G>A	-	intron_variant	-	3/49
ENST00000423487.2	c.161-371G>A	-	intron_variant	-	3/7
NM_005502.4	c.161-371G>A	-	intron_variant	-	3/49