Variant ID: 9-107664301-C-T

NM_005502.3(ABCA1):c.66+1594G>A

This variant was identified in 84 publications




Publications:


Genetic Susceptibility, Diet Quality, and Two-Step Progression in Drusen Size.

Investigative Ophthalmology & Visual Science
BMJ Merle, B Rosner, JM Seddon
Publication Date: 2020-05-11

Variant appearance in text: rs1883025
PMID: 32407518
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Risk factors for progression of age-related macular degeneration.

Ophthalmic & Physiological Optics : The Journal Of The British College Of Ophthalmic Opticians (Optometrists)
TJ Heesterbeek, L Lorés-Motta, CB Hoyng, YTE Lechanteur, AI den Hollander
Publication Date: 2020-02-25

Variant appearance in text: rs1883025
PMID: 32100327
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Association Between Perifoveal Drusen Burden Determined by OCT and Genetic Risk in Early and Intermediate Age-Related Macular Degeneration.

Investigative Ophthalmology & Visual Science
JM Seddon, JP Dossett, R Widjajahakim, B Rosner
Publication Date: 2019-10-01

Variant appearance in text: rs1883025
PMID: 31658355
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Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration.

Elife
F Storti, K Klee, V Todorova, R Steiner, A Othman, S van der Velde-Visser, M Samardzija, I Meneau, M Barben, D Karademir, V Pauzuolyte, SL Boye, F Blaser, C Ullmer, JL Dunaief, T Hornemann, L Rohrer, A den Hollander, A von Eckardstein, J Fingerle, C Maugeais, C Grimm
Publication Date: 2019-03-13

Variant appearance in text: rs1883025
PMID: 30864945
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Analysis of genetic polymorphisms for age-related macular degeneration (AMD) in Chinese Tujia ethnic minority group.

Bmc Medical Genetics
S Liu, M Wu, B Zhang, X Xiong, H Wang, X Zhou
Publication Date: 2019-01-29

Variant appearance in text: rs1883025
PMID: 30696427
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Identifying genetic markers associated with susceptibility to cardiovascular diseases.

Future Science Oa
H Shukla, JL Mason, A Sabyah
Publication Date: 2019-01

Variant appearance in text: rs1883025
PMID: 30652019
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Metabolic Syndrome Prediction Using Machine Learning Models with Genetic and Clinical Information from a Nonobese Healthy Population.

Genomics & Informatics
EK Choe, H Rhee, S Lee, E Shin, SW Oh, JE Lee, SH Choi
Publication Date: 2018-12

Variant appearance in text: rs1883025
PMID: 30602092
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Vitamin E Metabolic Effects and Genetic Variants: A Challenge for Precision Nutrition in Obesity and Associated Disturbances.

Nutrients
S Galmés, F Serra, A Palou
Publication Date: 2018-12-04

Variant appearance in text: rs1883025
PMID: 30518135
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Identification of 26 novel loci that confer susceptibility to early-onset coronary artery disease in a Japanese population.

Biomedical Reports
Y Yamada, Y Yasukochi, K Kato, M Oguri, H Horibe, T Fujimaki, I Takeuchi, J Sakuma
Publication Date: 2018-11

Variant appearance in text: rs1883025
PMID: 30402224
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Validated Prediction Models for Macular Degeneration Progression and Predictors of Visual Acuity Loss Identify High-Risk Individuals.

American Journal Of Ophthalmology
JM Seddon, B Rosner
Publication Date: 2019-02

Variant appearance in text: rs1883025
PMID: 30389371
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Genetic and secondary causes of severe HDL deficiency and cardiovascular disease.

Journal Of Lipid Research
AS Geller, EY Polisecki, MR Diffenderfer, BF Asztalos, SK Karathanasis, RA Hegele, EJ Schaefer
Publication Date: 2018-12

Variant appearance in text: rs1883025
PMID: 30333156
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Association of Genes in the High-Density Lipoprotein Metabolic Pathway with Polypoidal Choroidal Vasculopathy in Asian Population: A Systematic Review and Meta-Analysis.

Journal Of Ophthalmology
MZ Yuan, RA Han, CX Zhang, YX Chen
Publication Date: 2018

Variant appearance in text: rs1883025
PMID: 29977615
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Which Risk Factors Causally Influence Dementia? A Systematic Review of Mendelian Randomization Studies.

Journal Of Alzheimer'S Disease : Jad
E Kuźma, E Hannon, A Zhou, I Lourida, A Bethel, DA Levine, K Lunnon, J Thompson-Coon, E Hyppönen, DJ Llewellyn
Publication Date: 2018

Variant appearance in text: rs1883025
PMID: 29865062
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Interactions between Genetics and Sugar-Sweetened Beverage Consumption on Health Outcomes: A Review of Gene-Diet Interaction Studies.

Frontiers In Endocrinology
DE Haslam, NM McKeown, MA Herman, AH Lichtenstein, HS Dashti
Publication Date: 2017

Variant appearance in text: rs1883025
PMID: 29375475
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Genetic and environmental factors strongly influence risk, severity and progression of age-related macular degeneration.

Signal Transduction And Targeted Therapy
W Wang, K Gawlik, J Lopez, C Wen, J Zhu, F Wu, W Shi, S Scheibler, H Cai, R Vairavan, A Shi, W Haw, H Ferreyra, M Zhang, S Chang, K Zhang
Publication Date: 2016

Variant appearance in text: rs1883025
PMID: 29263899
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Genetic risk factors for late age-related macular degeneration in India.

The British Journal Of Ophthalmology
A Rajendran, P Dhoble, P Sundaresan, V Saravanan, P Vashist, D Nitsch, L Smeeth, U Chakravarthy, RD Ravindran, AE Fletcher
Publication Date: 2018-09

Variant appearance in text: rs1883025
PMID: 29259020
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Advances in Age-related Macular Degeneration Understanding and Therapy.

Us Ophthalmic Review
JW Miller, S Bagheri, DG Vavvas
Publication Date: 2017

Variant appearance in text: rs1883025
PMID: 29142592
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Genetic Polymorphisms of CFH and ARMS2 Do Not Predict Response to Antioxidants and Zinc in Patients with Age-Related Macular Degeneration: Independent Statistical Evaluations of Data from the Age-Related Eye Disease Study.

Ophthalmology
MJ Assel, F Li, Y Wang, AS Allen, KA Baggerly, AJ Vickers
Publication Date: 2018-03

Variant appearance in text: rs1883025
PMID: 29032853
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HDL-cholesterol levels and risk of age-related macular degeneration: a multiethnic genetic study using Mendelian randomization.

International Journal Of Epidemiology
Q Fan, JC Maranville, L Fritsche, X Sim, CMG Cheung, LJ Chen, M Gorski, K Yamashiro, J Ahn, A Laude, R Dorajoo, TH Lim, YY Teo, RO Blaustein, N Yoshimura, KH Park, CP Pang, ES Tai, CC Khor, TY Wong, H Runz, CY Cheng
Publication Date: 2017-12-01

Variant appearance in text: rs1883025
PMID: 29025108
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HDL-cholesterol concentration in pregnant Chinese Han women of late second trimester associated with genetic variants in CETP, ABCA1, APOC3, and GALNT2.

Oncotarget
M Cui, W Li, L Ma, F Ping, J Liu, X Wu, J Mao, X Wang, M Nie
Publication Date: 2017-08-22

Variant appearance in text: rs1883025
PMID: 28915626
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Polygenic determinants in extremes of high-density lipoprotein cholesterol.

Journal Of Lipid Research
JS Dron, J Wang, C Low-Kam, SA Khetarpal, JF Robinson, AD McIntyre, MR Ban, H Cao, D Rhainds, MP Dubé, DJ Rader, G Lettre, JC Tardif, RA Hegele
Publication Date: 2017-11

Variant appearance in text: rs1883025
PMID: 28870971
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Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.

Lipids In Health And Disease
CS Paththinige, ND Sirisena, V Dissanayake
Publication Date: 2017-06-02

Variant appearance in text: rs1883025
PMID: 28577571
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Mendelian Randomization Implicates High-Density Lipoprotein Cholesterol-Associated Mechanisms in Etiology of Age-Related Macular Degeneration.

Ophthalmology
S Burgess, G Davey Smith
Publication Date: 2017-08

Variant appearance in text: rs1883025
PMID: 28456421
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Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study.

Scientific Reports
S Christie, S Robiou-du-Pont, SS Anand, KM Morrison, SD McDonald, G Paré, SA Atkinson, KK Teo, D Meyre
Publication Date: 2017-03-06

Variant appearance in text: rs1883025
PMID: 28250428
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The Association between the Lipids Levels in Blood and Risk of Age-Related Macular Degeneration.

Nutrients
Y Wang, M Wang, X Zhang, Q Zhang, J Nie, M Zhang, X Liu, L Ma
Publication Date: 2016-10-22

Variant appearance in text: rs1883025
PMID: 27782072
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Associations of genetic variants for adult lipid levels with lipid levels in children. The Generation R Study.

Journal Of Lipid Research
A Latsuzbaia, VW Jaddoe, A Hofman, OH Franco, JF Felix
Publication Date: 2016-12

Variant appearance in text: rs1883025
PMID: 27777320
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The Association between LIPC rs493258 Polymorphism and the Susceptibility to Age-Related Macular Degeneration.

International Journal Of Environmental Research And Public Health
Y Wang, M Wang, X Zhang, J Nie, M Zhang, X Liu, L Ma
Publication Date: 2016-10-18

Variant appearance in text: rs1883025
PMID: 27763569
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Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.

Nature Genetics
V Iotchkova, J Huang, JA Morris, D Jain, C Barbieri, K Walter, JL Min, L Chen, W Astle, M Cocca, P Deelen, H Elding, AE Farmaki, CS Franklin, M Franberg, TR Gaunt, A Hofman, T Jiang, ME Kleber, G Lachance, J Luan, G Malerba, A Matchan, D Mead, Y Memari, I Ntalla, K Panoutsopoulou, R Pazoki, JRB Perry, F Rivadeneira, M Sabater-Lleal, B Sennblad, SY Shin, L Southam, M Traglia, F van Dijk, EM van Leeuwen, G Zaza, W Zhang, , N Amin, A Butterworth, JC Chambers, G Dedoussis, A Dehghan, OH Franco, L Franke, M Frontini, G Gambaro, P Gasparini, A Hamsten, A Issacs, JS Kooner, C Kooperberg, C Langenberg, W Marz, RA Scott, MA Swertz, D Toniolo, AG Uitterlinden, CM van Duijn, H Watkins, E Zeggini, MT Maurano, NJ Timpson, AP Reiner, PL Auer, N Soranzo
Publication Date: 2016-11

Variant appearance in text: rs1883025
PMID: 27668658
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CYP4F2 (rs2108622) Gene Polymorphism Association with Age-Related Macular Degeneration.

Advances In Medicine
R Sakiene, A Vilkeviciute, L Kriauciuniene, VJ Balciuniene, D Buteikiene, G Miniauskiene, R Liutkeviciene
Publication Date: 2016

Variant appearance in text: rs1883025
PMID: 27652291
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AMD-like retinopathy associated with intravenous iron.

Experimental Eye Research
D Song, LN Kanu, Y Li, KL Kelly, RK Bhuyan, T Aleman, JI Morgan, JL Dunaief
Publication Date: 2016-10

Variant appearance in text: rs1883025
PMID: 27565570
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Analysis with the exome array identifies multiple new independent variants in lipid loci.

Human Molecular Genetics
S Kanoni, NG Masca, KE Stirrups, TV Varga, HR Warren, RA Scott, L Southam, W Zhang, H Yaghootkar, M Müller-Nurasyid, A Couto Alves, RJ Strawbridge, L Lataniotis, N An Hashim, C Besse, A Boland, PS Braund, JM Connell, A Dominiczak, AE Farmaki, S Franks, H Grallert, JH Jansson, M Karaleftheri, S Keinänen-Kiukaanniemi, A Matchan, D Pasko, A Peters, N Poulter, NW Rayner, F Renström, O Rolandsson, M Sabater-Lleal, B Sennblad, P Sever, D Shields, A Silveira, AV Stanton, K Strauch, M Tomaszewski, E Tsafantakis, M Waldenberger, AI Blakemore, G Dedoussis, SA Escher, JS Kooner, MI McCarthy, CN Palmer, , A Hamsten, MJ Caulfield, TM Frayling, MD Tobin, MR Jarvelin, E Zeggini, C Gieger, JC Chambers, NJ Wareham, PB Munroe, PW Franks, NJ Samani, P Deloukas
Publication Date: 2016-09-15

Variant appearance in text: rs1883025
PMID: 27466198
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Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.

Scientific Reports
JE Below, EJ Parra, ER Gamazon, J Torres, S Krithika, S Candille, Y Lu, A Manichakul, J Peralta-Romero, Q Duan, Y Li, AP Morris, O Gottesman, E Bottinger, XQ Wang, KD Taylor, YD Ida Chen, JI Rotter, SS Rich, RJ Loos, H Tang, NJ Cox, M Cruz, CL Hanis, A Valladares-Salgado
Publication Date: 2016-01-19

Variant appearance in text: rs1883025
PMID: 26780889
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Predictors of Response to Intravitreal Anti-Vascular Endothelial Growth Factor Treatment of Age-Related Macular Degeneration.

American Journal Of Ophthalmology
AR Shah, S Williams, CR Baumal, B Rosner, JS Duker, JM Seddon
Publication Date: 2016-03

Variant appearance in text: rs1883025
PMID: 26705092
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Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians.

Diabetologia
AK Nair, P Piaggi, NA McLean, M Kaur, S Kobes, WC Knowler, C Bogardus, RL Hanson, LJ Baier
Publication Date: 2016-03

Variant appearance in text: rs1883025
PMID: 26670163
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Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.

Plos Medicine
SD Østergaard, S Mukherjee, SJ Sharp, P Proitsi, LA Lotta, F Day, JR Perry, KL Boehme, S Walter, JS Kauwe, LE Gibbons, , , , EB Larson, JF Powell, C Langenberg, PK Crane, NJ Wareham, RA Scott
Publication Date: 2015-06

Variant appearance in text: rs1883025
PMID: 26079503
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Association of OCT derived drusen measurements with AMD associated-genotypic SNPs in Amish population.

Journal Of Clinical Medicine
VR Chavali, B Diniz, J Huang, GS Ying, SR Sadda, D Stambolian
Publication Date: 2015

Variant appearance in text: rs1883025
PMID: 25893111
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Using multivariable Mendelian randomization to disentangle the causal effects of lipid fractions.

Plos One
S Burgess, DF Freitag, H Khan, DN Gorman, SG Thompson
Publication Date: 2014

Variant appearance in text: rs1883025
PMID: 25302496
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Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study.

Investigative Ophthalmology & Visual Science
NA Restrepo, KL Spencer, R Goodloe, TA Garrett, G Heiss, P Bůžková, N Jorgensen, RA Jensen, TC Matise, LA Hindorff, BE Klein, R Klein, TY Wong, CY Cheng, BK Cornes, ES Tai, MD Ritchie, JL Haines, DC Crawford
Publication Date: 2014-09-09

Variant appearance in text: rs1883025
PMID: 25205864
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Extension of GWAS results for lipid-related phenotypes to extreme obesity using electronic health record (EHR) data and the Metabochip.

Frontiers In Genetics
A Parihar, GC Wood, X Chu, Q Jin, G Argyropoulos, CD Still, AR Shuldiner, BD Mitchell, GS Gerhard
Publication Date: 2014

Variant appearance in text: rs1883025
PMID: 25147553
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Lipids, lipid genes, and incident age-related macular degeneration: the three continent age-related macular degeneration consortium.

American Journal Of Ophthalmology
R Klein, CE Myers, GH Buitendijk, E Rochtchina, X Gao, PT de Jong, TA Sivakumaran, G Burlutsky, R McKean-Cowdin, A Hofman, SK Iyengar, KE Lee, BH Stricker, JR Vingerling, P Mitchell, BE Klein, CC Klaver, JJ Wang
Publication Date: 2014-09

Variant appearance in text: rs1883025
PMID: 24879949
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Macular xanthophylls, lipoprotein-related genes, and age-related macular degeneration.

The American Journal Of Clinical Nutrition
E Koo, M Neuringer, JP SanGiovanni
Publication Date: 2014-07

Variant appearance in text: rs1883025
PMID: 24829491
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Cholesterol in the retina: the best is yet to come.

Progress In Retinal And Eye Research
IA Pikuleva, CA Curcio
Publication Date: 2014-07

Variant appearance in text: rs1883025
PMID: 24704580
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A Simple Scalable Association Hypothesis Test Combining Gene-wide Evidence From Multiple Polymorphisms.

British Journal Of Medicine And Medical Research
D Vaidya, LR Yanek, RA Mathias, TF Moy, DM Becker, LC Becker
Publication Date: 2014-03

Variant appearance in text: rs1883025
PMID: 24688980
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Elevated high-density lipoprotein cholesterol and age-related macular degeneration: the Alienor study.

Plos One
A Cougnard-Grégoire, MN Delyfer, JF Korobelnik, MB Rougier, M Le Goff, JF Dartigues, P Barberger-Gateau, C Delcourt
Publication Date: 2014

Variant appearance in text: rs1883025
PMID: 24608419
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Pathogenesis of coronary artery disease: focus on genetic risk factors and identification of genetic variants.

The Application Of Clinical Genetics
S Sayols-Baixeras, C Lluís-Ganella, G Lucas, R Elosua
Publication Date: 2014

Variant appearance in text: rs1883025
PMID: 24520200
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Three new genetic loci (R1210C in CFH, variants in COL8A1 and RAD51B) are independently related to progression to advanced macular degeneration.

Plos One
JM Seddon, R Reynolds, Y Yu, B Rosner
Publication Date: 2014

Variant appearance in text: rs1883025
PMID: 24498017
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Lipid trait-associated genetic variation is associated with gallstone disease in the diverse Third National Health and Nutrition Examination Survey (NHANES III).

Bmc Medical Genetics
R Goodloe, K Brown-Gentry, NB Gillani, H Jin, P Mayo, M Allen, B McClellan, J Boston, C Sutcliffe, N Schnetz-Boutaud, HH Dilks, DC Crawford
Publication Date: 2013-11-21

Variant appearance in text: rs1883025
PMID: 24256507
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Association of HDL-related loci with age-related macular degeneration and plasma lutein and zeaxanthin: the Alienor study.

Plos One
BM Merle, C Maubaret, JF Korobelnik, MN Delyfer, MB Rougier, JC Lambert, P Amouyel, F Malet, M Le Goff, JF Dartigues, P Barberger-Gateau, C Delcourt
Publication Date: 2013

Variant appearance in text: rs1883025
PMID: 24223199
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Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations.

Cerebrovascular Diseases (Basel, Switzerland)
SY Chou, JM Shulman, BT Keenan, EA Secor, AS Buchman, J Schneider, DA Bennett, PL De Jager
Publication Date: 2013

Variant appearance in text: rs1883025
PMID: 24135527
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Prediction of age-related macular degeneration in the general population: the Three Continent AMD Consortium.

Ophthalmology
GHS Buitendijk, E Rochtchina, C Myers, CM van Duijn, KE Lee, BEK Klein, SM Meuer, PTVM de Jong, EG Holliday, AG Tan, AG Uitterlinden, TS Sivakumaran, J Attia, A Hofman, P Mitchell, JR Vingerling, SK Iyengar, ACJW Janssens, JJ Wang, R Klein, CCW Klaver
Publication Date: 2013-12

Variant appearance in text: rs1883025
PMID: 24120328
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Common variants associated with plasma triglycerides and risk for coronary artery disease.

Nature Genetics
R Do, CJ Willer, EM Schmidt, S Sengupta, C Gao, GM Peloso, S Gustafsson, S Kanoni, A Ganna, J Chen, ML Buchkovich, S Mora, JS Beckmann, JL Bragg-Gresham, HY Chang, A Demirkan, HM Den Hertog, LA Donnelly, GB Ehret, T Esko, MF Feitosa, T Ferreira, K Fischer, P Fontanillas, RM Fraser, DF Freitag, D Gurdasani, K Heikkilä, E Hyppönen, A Isaacs, AU Jackson, A Johansson, T Johnson, M Kaakinen, J Kettunen, ME Kleber, X Li, J Luan, LP Lyytikäinen, PK Magnusson, M Mangino, E Mihailov, ME Montasser, M Müller-Nurasyid, IM Nolte, JR O'Connell, CD Palmer, M Perola, AK Petersen, S Sanna, R Saxena, SK Service, S Shah, D Shungin, C Sidore, C Song, RJ Strawbridge, I Surakka, T Tanaka, TM Teslovich, G Thorleifsson, EG Van den Herik, BF Voight, KA Volcik, LL Waite, A Wong, Y Wu, W Zhang, D Absher, G Asiki, I Barroso, LF Been, JL Bolton, LL Bonnycastle, P Brambilla, MS Burnett, G Cesana, M Dimitriou, AS Doney, A Döring, P Elliott, SE Epstein, GI Eyjolfsson, B Gigante, MO Goodarzi, H Grallert, ML Gravito, CJ Groves, G Hallmans, AL Hartikainen, C Hayward, D Hernandez, AA Hicks, H Holm, YJ Hung, T Illig, MR Jones, P Kaleebu, JJ Kastelein, KT Khaw, E Kim, N Klopp, P Komulainen, M Kumari, C Langenberg, T Lehtimäki, SY Lin, J Lindström, RJ Loos, F Mach, WL McArdle, C Meisinger, BD Mitchell, G Müller, R Nagaraja, N Narisu, TV Nieminen, RN Nsubuga, I Olafsson, KK Ong, A Palotie, T Papamarkou, C Pomilla, A Pouta, DJ Rader, MP Reilly, PM Ridker, F Rivadeneira, I Rudan, A Ruokonen, N Samani, H Scharnagl, J Seeley, K Silander, A Stančáková, K Stirrups, AJ Swift, L Tiret, AG Uitterlinden, LJ van Pelt, S Vedantam, N Wainwright, C Wijmenga, SH Wild, G Willemsen, T Wilsgaard, JF Wilson, EH Young, JH Zhao, LS Adair, D Arveiler, TL Assimes, S Bandinelli, F Bennett, M Bochud, BO Boehm, DI Boomsma, IB Borecki, SR Bornstein, P Bovet, M Burnier, H Campbell, A Chakravarti, JC Chambers, YD Chen, FS Collins, RS Cooper, J Danesh, G Dedoussis, U de Faire, AB Feranil, J Ferrières, L Ferrucci, NB Freimer, C Gieger, LC Groop, V Gudnason, U Gyllensten, A Hamsten, TB Harris, A Hingorani, JN Hirschhorn, A Hofman, GK Hovingh, CA Hsiung, SE Humphries, SC Hunt, K Hveem, C Iribarren, MR Järvelin, A Jula, M Kähönen, J Kaprio, A Kesäniemi, M Kivimaki, JS Kooner, PJ Koudstaal, RM Krauss, D Kuh, J Kuusisto, KO Kyvik, M Laakso, TA Lakka, L Lind, CM Lindgren, NG Martin, W März, MI McCarthy, CA McKenzie, P Meneton, A Metspalu, L Moilanen, AD Morris, PB Munroe, I Njølstad, NL Pedersen, C Power, PP Pramstaller, JF Price, BM Psaty, T Quertermous, R Rauramaa, D Saleheen, V Salomaa, DK Sanghera, J Saramies, PE Schwarz, WH Sheu, AR Shuldiner, A Siegbahn, TD Spector, K Stefansson, DP Strachan, BO Tayo, E Tremoli, J Tuomilehto, M Uusitupa, CM van Duijn, P Vollenweider, L Wallentin, NJ Wareham, JB Whitfield, BH Wolffenbuttel, D Altshuler, JM Ordovas, E Boerwinkle, CN Palmer, U Thorsteinsdottir, DI Chasman, JI Rotter, PW Franks, S Ripatti, LA Cupples, MS Sandhu, SS Rich, M Boehnke, P Deloukas, KL Mohlke, E Ingelsson, GR Abecasis, MJ Daly, BM Neale, S Kathiresan
Publication Date: 2013-11

Variant appearance in text: rs1883025
PMID: 24097064
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Genetics of lipid traits and relationship to coronary artery disease.

Current Cardiology Reports
TE Keenan, DJ Rader
Publication Date: 2013-09

Variant appearance in text: rs1883025
PMID: 23881580
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Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.

American Journal Of Human Genetics
MA Coram, Q Duan, TJ Hoffmann, T Thornton, JW Knowles, NA Johnson, HM Ochs-Balcom, TA Donlon, LW Martin, CB Eaton, JG Robinson, NJ Risch, X Zhu, C Kooperberg, Y Li, AP Reiner, H Tang
Publication Date: 2013-06-06

Variant appearance in text: rs1883025
PMID: 23726366
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Association analysis of dyslipidemia-related genes in diabetic nephropathy.

Plos One
GJ McKay, DA Savage, CC Patterson, G Lewis, AJ McKnight, AP Maxwell,
Publication Date: 2013

Variant appearance in text: rs1883025
PMID: 23555584
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Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained.

Plos Genetics
Y Wu, LL Waite, AU Jackson, WH Sheu, S Buyske, D Absher, DK Arnett, E Boerwinkle, LL Bonnycastle, CL Carty, I Cheng, B Cochran, DC Croteau-Chonka, L Dumitrescu, CB Eaton, N Franceschini, X Guo, BE Henderson, LA Hindorff, E Kim, L Kinnunen, P Komulainen, WJ Lee, L Le Marchand, Y Lin, J Lindström, O Lingaas-Holmen, SL Mitchell, N Narisu, JG Robinson, F Schumacher, A Stančáková, J Sundvall, YJ Sung, AJ Swift, WC Wang, L Wilkens, T Wilsgaard, AM Young, LS Adair, CM Ballantyne, P Bůžková, A Chakravarti, FS Collins, D Duggan, AB Feranil, LT Ho, YJ Hung, SC Hunt, K Hveem, JM Juang, AY Kesäniemi, J Kuusisto, M Laakso, TA Lakka, IT Lee, MF Leppert, TC Matise, L Moilanen, I Njølstad, U Peters, T Quertermous, R Rauramaa, JI Rotter, J Saramies, J Tuomilehto, M Uusitupa, TD Wang, M Boehnke, CA Haiman, YD Chen, C Kooperberg, TL Assimes, DC Crawford, CA Hsiung, KE North, KL Mohlke
Publication Date: 2013-03

Variant appearance in text: rs1883025
PMID: 23555291
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Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.

Journal Of Medical Genetics
D Weissglas-Volkov, CA Aguilar-Salinas, E Nikkola, KA Deere, I Cruz-Bautista, O Arellano-Campos, LL Muñoz-Hernandez, L Gomez-Munguia, ML Ordoñez-Sánchez, PM Reddy, AJ Lusis, N Matikainen, MR Taskinen, L Riba, RM Cantor, JS Sinsheimer, T Tusie-Luna, P Pajukanta
Publication Date: 2013-05

Variant appearance in text: rs1883025
PMID: 23505323
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Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study.

Cardiovascular Diabetology
CM Povel, JM Boer, NC Onland-Moret, ME Dollé, EJ Feskens, YT van der Schouw
Publication Date: 2012-10-29

Variant appearance in text: rs1883025
PMID: 23101478
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Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases.

Bmc Medical Genetics
S Huhn, M Bevier, A Rudolph, B Pardini, A Naccarati, R Hein, M Hoffmeister, L Vodickova, J Novotny, H Brenner, J Chang-Claude, K Hemminki, P Vodicka, A Försti
Publication Date: 2012-10-05

Variant appearance in text: rs1883025
PMID: 23036011
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Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes.

Ophthalmology
L Sobrin, S Ripke, Y Yu, J Fagerness, TR Bhangale, PL Tan, EH Souied, GH Buitendijk, JE Merriam, AJ Richardson, S Raychaudhuri, R Reynolds, KA Chin, AY Lee, N Leveziel, DJ Zack, P Campochiaro, RT Smith, GR Barile, RE Hogg, U Chakravarthy, TW Behrens, AG Uitterlinden, CM van Duijn, JR Vingerling, MA Brantley, PN Baird, CC Klaver, R Allikmets, N Katsanis, RR Graham, JP Ioannidis, MJ Daly, JM Seddon
Publication Date: 2012-09

Variant appearance in text: rs1883025
PMID: 22705344
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Genetic factors for choroidal neovascularization associated with high myopia.

Investigative Ophthalmology & Visual Science
N Leveziel, Y Yu, R Reynolds, A Tai, W Meng, V Caillaux, P Calvas, B Rosner, F Malecaze, EH Souied, JM Seddon
Publication Date: 2012-07-27

Variant appearance in text: rs1883025
PMID: 22678500
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Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.

Plos One
K Musunuru, SP Romaine, G Lettre, JG Wilson, KA Volcik, MY Tsai, HA Taylor, PJ Schreiner, JI Rotter, SS Rich, S Redline, BM Psaty, GJ Papanicolaou, JM Ordovas, K Liu, RM Krauss, NL Glazer, SB Gabriel, M Fornage, LA Cupples, SG Buxbaum, E Boerwinkle, CM Ballantyne, S Kathiresan, DJ Rader
Publication Date: 2012

Variant appearance in text: rs1883025
PMID: 22629316
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Prospective assessment of genetic effects on progression to different stages of age-related macular degeneration using multistate Markov models.

Investigative Ophthalmology & Visual Science
Y Yu, R Reynolds, B Rosner, MJ Daly, JM Seddon
Publication Date: 2012-03

Variant appearance in text: rs1883025
PMID: 22247473
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Association of genetic loci with blood lipids in the Chinese population.

Plos One
Z Zhang, L Tao, Z Chen, D Zhou, M Kan, D Zhang, C Li, L He, Y Liu
Publication Date: 2011

Variant appearance in text: rs1883025
PMID: 22073310
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Evaluation of new and established age-related macular degeneration susceptibility genes in the Women's Health Initiative Sight Exam (WHI-SE) Study.

American Journal Of Ophthalmology
I Peter, GS Huggins, JM Ordovas, M Haan, JM Seddon
Publication Date: 2011-12

Variant appearance in text: rs1883025
PMID: 21906714
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Implications of discoveries from genome-wide association studies in current cardiovascular practice.

World Journal Of Cardiology
P Jeemon, K Pettigrew, C Sainsbury, D Prabhakaran, S Padmanabhan
Publication Date: 2011-07-26

Variant appearance in text: rs1883025
PMID: 21860704
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Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study.

Plos Genetics
L Dumitrescu, CL Carty, K Taylor, FR Schumacher, LA Hindorff, JL Ambite, G Anderson, LG Best, K Brown-Gentry, P Bůžková, CS Carlson, B Cochran, SA Cole, RB Devereux, D Duggan, CB Eaton, M Fornage, N Franceschini, J Haessler, BV Howard, KC Johnson, S Laston, LN Kolonel, ET Lee, JW MacCluer, TA Manolio, SA Pendergrass, M Quibrera, RV Shohet, LR Wilkens, CA Haiman, L Le Marchand, S Buyske, C Kooperberg, KE North, DC Crawford
Publication Date: 2011-06

Variant appearance in text: rs1883025
PMID: 21738485
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Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration.

Human Molecular Genetics
Y Yu, TR Bhangale, J Fagerness, S Ripke, G Thorleifsson, PL Tan, EH Souied, AJ Richardson, JE Merriam, GH Buitendijk, R Reynolds, S Raychaudhuri, KA Chin, L Sobrin, E Evangelou, PH Lee, AY Lee, N Leveziel, DJ Zack, B Campochiaro, P Campochiaro, RT Smith, GR Barile, RH Guymer, R Hogg, U Chakravarthy, LD Robman, O Gustafsson, H Sigurdsson, W Ortmann, TW Behrens, K Stefansson, AG Uitterlinden, CM van Duijn, JR Vingerling, CC Klaver, R Allikmets, MA Brantley, PN Baird, N Katsanis, U Thorsteinsdottir, JP Ioannidis, MJ Daly, RR Graham, JM Seddon
Publication Date: 2011-09-15

Variant appearance in text: rs1883025
PMID: 21665990
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Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration.

Investigative Ophthalmology & Visual Science
Y Yu, R Reynolds, J Fagerness, B Rosner, MJ Daly, JM Seddon
Publication Date: 2011-06-28

Variant appearance in text: rs1883025
PMID: 21447678
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ARMS2/HTRA1 locus can confer differential susceptibility to the advanced subtypes of age-related macular degeneration.

American Journal Of Ophthalmology
L Sobrin, R Reynolds, Y Yu, J Fagerness, N Leveziel, PS Bernstein, EH Souied, MJ Daly, JM Seddon
Publication Date: 2011-02

Variant appearance in text: rs1883025
PMID: 21122828
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Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review.

American Journal Of Epidemiology
OA Panagiotou, E Evangelou, JP Ioannidis
Publication Date: 2010-10-15

Variant appearance in text: rs1883025
PMID: 20876667
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Association of common DNA sequence variants at 33 genetic loci with blood lipids in individuals of African ancestry from Jamaica.

Human Genetics
R Gupta, K Ejebe, J Butler, G Lettre, H Lyon, C Guiducci, R Wilks, F Bennett, T Forrester, B Tayo, K Musunuru, J Hirschhorn, S Kathiresan, RS Cooper, CA McKenzie
Publication Date: 2010-11

Variant appearance in text: rs1883025
PMID: 20839009
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Interpretation of association signals and identification of causal variants from genome-wide association studies.

American Journal Of Human Genetics
K Wang, SP Dickson, CA Stolle, ID Krantz, DB Goldstein, H Hakonarson
Publication Date: 2010-05-14

Variant appearance in text: rs1883025
PMID: 20434130
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Genetic causes of high and low serum HDL-cholesterol.

Journal Of Lipid Research
D Weissglas-Volkov, P Pajukanta
Publication Date: 2010-08

Variant appearance in text: rs1883025
PMID: 20421590
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The genetics of obesity and the metabolic syndrome.

Endocrine, Metabolic & Immune Disorders Drug Targets
KL Monda, KE North, SC Hunt, DC Rao, MA Province, AT Kraja
Publication Date: 2010-06

Variant appearance in text: rs1883025
PMID: 20406164
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Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).

Proceedings Of The National Academy Of Sciences Of The United States Of America
BM Neale, J Fagerness, R Reynolds, L Sobrin, M Parker, S Raychaudhuri, PL Tan, EC Oh, JE Merriam, E Souied, PS Bernstein, B Li, JM Frederick, K Zhang, MA Brantley, AY Lee, DJ Zack, B Campochiaro, P Campochiaro, S Ripke, RT Smith, GR Barile, N Katsanis, R Allikmets, MJ Daly, JM Seddon
Publication Date: 2010-04-20

Variant appearance in text: rs1883025
PMID: 20385826
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Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.

Proceedings Of The National Academy Of Sciences Of The United States Of America
W Chen, D Stambolian, AO Edwards, KE Branham, M Othman, J Jakobsdottir, N Tosakulwong, MA Pericak-Vance, PA Campochiaro, ML Klein, PL Tan, YP Conley, A Kanda, L Kopplin, Y Li, KJ Augustaitis, AJ Karoukis, WK Scott, A Agarwal, JL Kovach, SG Schwartz, EA Postel, M Brooks, KH Baratz, WL Brown, , AJ Brucker, A Orlin, G Brown, A Ho, C Regillo, L Donoso, L Tian, B Kaderli, D Hadley, SA Hagstrom, NS Peachey, R Klein, BE Klein, N Gotoh, K Yamashiro, F Ferris Iii, JA Fagerness, R Reynolds, LA Farrer, IK Kim, JW Miller, M Cortón, A Carracedo, M Sanchez-Salorio, EW Pugh, KF Doheny, M Brion, MM Deangelis, DE Weeks, DJ Zack, EY Chew, JR Heckenlively, N Yoshimura, SK Iyengar, PJ Francis, N Katsanis, JM Seddon, JL Haines, MB Gorin, GR Abecasis, A Swaroop
Publication Date: 2010-04-20

Variant appearance in text: rs1883025
PMID: 20385819
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Genome-wide association of lipid-lowering response to statins in combined study populations.

Plos One
MJ Barber, LM Mangravite, CL Hyde, DI Chasman, JD Smith, CA McCarty, X Li, RA Wilke, MJ Rieder, PT Williams, PM Ridker, A Chatterjee, JI Rotter, DA Nickerson, M Stephens, RM Krauss
Publication Date: 2010-03-22

Variant appearance in text: rs1883025
PMID: 20339536
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Genetics of lipid disorders.

Current Opinion In Cardiology
J Pirruccello, S Kathiresan
Publication Date: 2010-05

Variant appearance in text: rs1883025
PMID: 20224388
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Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples.

Circulation. Cardiovascular Genetics
D Weissglas-Volkov, CA Aguilar-Salinas, JS Sinsheimer, L Riba, A Huertas-Vazquez, ML Ordoñez-Sánchez, R Rodriguez-Guillen, RM Cantor, T Tusie-Luna, P Pajukanta
Publication Date: 2010-02

Variant appearance in text: rs1883025
PMID: 20160193
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Association between a literature-based genetic risk score and cardiovascular events in women.

Jama
NP Paynter, DI Chasman, G Paré, JE Buring, NR Cook, JP Miletich, PM Ridker
Publication Date: 2010-02-17

Variant appearance in text: rs1883025
PMID: 20159871
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Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.

Lipids In Health And Disease
J Ronald, R Rajagopalan, JE Ranchalis, JK Marshall, TS Hatsukami, PJ Heagerty, GP Jarvik
Publication Date: 2009-12-01

Variant appearance in text: rs1883025
PMID: 19951432
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Common variants at 30 loci contribute to polygenic dyslipidemia.

Nature Genetics
S Kathiresan, CJ Willer, GM Peloso, S Demissie, K Musunuru, EE Schadt, L Kaplan, D Bennett, Y Li, T Tanaka, BF Voight, LL Bonnycastle, AU Jackson, G Crawford, A Surti, C Guiducci, NP Burtt, S Parish, R Clarke, D Zelenika, KA Kubalanza, MA Morken, LJ Scott, HM Stringham, P Galan, AJ Swift, J Kuusisto, RN Bergman, J Sundvall, M Laakso, L Ferrucci, P Scheet, S Sanna, M Uda, Q Yang, KL Lunetta, J Dupuis, PI de Bakker, CJ O'Donnell, JC Chambers, JS Kooner, S Hercberg, P Meneton, EG Lakatta, A Scuteri, D Schlessinger, J Tuomilehto, FS Collins, L Groop, D Altshuler, R Collins, GM Lathrop, O Melander, V Salomaa, L Peltonen, M Orho-Melander, JM Ordovas, M Boehnke, GR Abecasis, KL Mohlke, LA Cupples
Publication Date: 2009-01

Variant appearance in text: rs1883025
PMID: 19060906
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Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms.

Molecular Neurodegeneration
SE Wahrle, AR Shah, AM Fagan, S Smemo, JS Kauwe, A Grupe, A Hinrichs, K Mayo, H Jiang, LJ Thal, AM Goate, DM Holtzman
Publication Date: 2007-04-12

Variant appearance in text: rs1883025
PMID: 17430597
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Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000374733.1 c.-114-12825G>A - intron_variant - 1/4
ENST00000374736.3 c.66+1594G>A - intron_variant - 2/49
ENST00000423487.2 c.66+1594G>A - intron_variant - 2/7
NM_005502.4 c.66+1594G>A - intron_variant - 2/49