Publications:

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The first prospective application of AIGS real-time fluorescence PCR in precise diagnosis and treatment of meningioma: Case report.

Frontiers In Neuroscience

Han, Zhe Z; Chi, Huizhong H; Li, Xueen X; Jia, Deze D; Li, Haiyan H; Ni, Shilei S; Zhang, Kailiang K; Feng, Zichao Z; Wang, Qingtong Q; Xue, Hao H; Li, Gang G

Publication Date: 2023

Variant appearance in text: KLF4: K409Q

PubMed Link: 37123372

Variant Present in the following documents:

• fnins-17-1158601.pdf

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KLF4 transcription factor in tumorigenesis.

Cell Death Discovery

He, Zhihong Z; He, Jie J; Xie, Keping K

Publication Date: 2023-04-08

Variant appearance in text: KLF4: K409Q

PubMed Link: 37031197

Variant Present in the following documents:

• Main text
• 41420_2023_Article_1416.pdf

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Specific gene expression signatures of low grade meningiomas.

Frontiers In Oncology

Tsitsikov, Erdyni N EN; Hameed, Sanaa S; Tavakol, Sherwin A SA; Stephens, Tressie M TM; Tsytsykova, Alla V AV; Garman, Lori L; Bi, Wenya Linda WL; Dunn, Ian F IF

Publication Date: 2023

Variant appearance in text: KLF4: K409Q

PubMed Link: 36937440

Variant Present in the following documents:

• Main text
• fonc-13-1126550.pdf

View BVdb publication page

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The multiomic landscape of meningiomas: a review and update.

Journal Of Neuro-Oncology

Wang, Justin Z JZ; Nassiri, Farshad F; Landry, Alexander P AP; Patil, Vikas V; Liu, Jeff J; Aldape, Kenneth K; Gao, Andrew A; Zadeh, Gelareh G

Publication Date: 2023-02-25

Variant appearance in text: KLF4: K409Q

PubMed Link: 36840836

Variant Present in the following documents:

• Main text
• 11060_2023_Article_4253.pdf

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Spinal meningiomas, from biology to management - A literature review.

Frontiers In Oncology

Serratrice, Nicolas N; Lameche, Imène I; Attieh, Christian C; Chalah, Moussa A MA; Faddoul, Joe J; Tarabay, Bilal B; Bou-Nassif, Rabih R; Ali, Youssef Y; Mattar, Joseph G JG; Nataf, François F; Ayache, Samar S SS; Abi Lahoud, Georges N GN

Publication Date: 2022

Variant appearance in text: KLF4: K409Q

PubMed Link: 36713513

Variant Present in the following documents:

• Main text
• fonc-12-1084404.pdf

View BVdb publication page

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Recent advances in the molecular prognostication of meningiomas.

Frontiers In Oncology

Wang, Elaina J EJ; Haddad, Alexander F AF; Young, Jacob S JS; Morshed, Ramin A RA; Wu, Joshua P H JPH; Salha, Diana M DM; Butowski, Nicholas N; Aghi, Manish K MK

Publication Date: 2022

Variant appearance in text: KLF4: K409Q

PubMed Link: 36686824

Variant Present in the following documents:

• Main text
• fonc-12-910199.pdf

View BVdb publication page

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The Role of Pharmacotherapy in Treatment of Meningioma: A Systematic Review.

Cancers

Shahbandi, Ataollah A; Shah, Darsh S DS; Hadley, Caroline C CC; Patel, Akash J AJ

Publication Date: 2023-01-12

Variant appearance in text: KLF4: K409Q

PubMed Link: 36672431

Variant Present in the following documents:

• cancers-15-00483.pdf

View BVdb publication page

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Signaling pathways in brain tumors and therapeutic interventions.

Signal Transduction And Targeted Therapy

Li, Shenglan S; Wang, Can C; Chen, Jinyi J; Lan, Yanjie Y; Zhang, Weichunbai W; Kang, Zhuang Z; Zheng, Yi Y; Zhang, Rong R; Yu, Jianyu J; Li, Wenbin W

Publication Date: 2023-01-04

Variant appearance in text: KLF4: K409Q

PubMed Link: 36596785

Variant Present in the following documents:

• 41392_2022_Article_1260.pdf

View BVdb publication page

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[Importancia pronóstica de las mutaciones del gen promotor de la transcriptasa inversa de la telomerasa en los meningiomas de alto grado].

Biomedica : Revista Del Instituto Nacional De Salud

Cañas, Alejandro A; Jiménez, Enrique E; Hakim, Fernando F; Mejía, Juan Armando JA; Ramón, Juan Fernando JF; Gómez, Diego D; Jaramillo-Velásquez, Daniel D; Bermúdez, Sonia S; Useche, Nicolás N; Pineda, Diego D; Cifuentes, Hernando H; Becerra, Antonio A; Muñoz, Álvaro Á; Santoyo, Nicolás N; Ruíz-Patiño, Alejandro A; Sotelo, Carolina C; Archila, Pilar P; Rodríguez, July J; Ávila, Jenny J; Ordoñez-Reyes, Camila C; García-Robledo, Juan Esteban JE; Ricaurte, Luisa L; Rojas, Leonardo L; Feo, Oscar O; Burgos, Remberto R; Ramírez, Carlos C; Arrieta, Oscar O; Zatarain-Barrón, Lucía L; Vargas, Carlos C; Carranza, Hernán H; Otero, Jorge J; Cardona, Andrés F AF

Publication Date: 2022-12-01

Variant appearance in text: KLF4: K409Q

PubMed Link: 36511679

Variant Present in the following documents:

• 2590-7379-bio-42-04-6100.pdf

View BVdb publication page

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Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor.

Cell Genomics

Islam, S M Ashiqul SMA; Díaz-Gay, Marcos M; Wu, Yang Y; Barnes, Mark M; Vangara, Raviteja R; Bergstrom, Erik N EN; He, Yudou Y; Vella, Mike M; Wang, Jingwei J; Teague, Jon W JW; Clapham, Peter P; Moody, Sarah S; Senkin, Sergey S; Li, Yun Rose YR; Riva, Laura L; Zhang, Tongwu T; Gruber, Andreas J AJ; Steele, Christopher D CD; Otlu, Burçak B; Khandekar, Azhar A; Abbasi, Ammal A; Humphreys, Laura L; Syulyukina, Natalia N; Brady, Samuel W SW; Alexandrov, Boian S BS; Pillay, Nischalan N; Zhang, Jinghui J; Adams, David J DJ; Martincorena, Iñigo I; Wedge, David C DC; Landi, Maria Teresa MT; Brennan, Paul P; Stratton, Michael R MR; Rozen, Steven G SG; Alexandrov, Ludmil B LB

Publication Date: 2022-11-09

Variant appearance in text: KLF4: K409Q

PubMed Link: 36388765

Variant Present in the following documents:

• mmc11.pdf
• main.pdf

View BVdb publication page

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Molecular diagnosis and treatment of meningiomas: an expert consensus (2022).

Chinese Medical Journal

Deng, Jiaojiao J; Hua, Lingyang L; Bian, Liuguan L; Chen, Hong H; Chen, Ligang L; Cheng, Hongwei H; Dou, Changwu C; Geng, Dangmurenjiapu D; Hong, Tao T; Ji, Hongming H; Jiang, Yugang Y; Lan, Qing Q; Li, Gang G; Liu, Zhixiong Z; Qi, Songtao S; Qu, Yan Y; Shi, Songsheng S; Sun, Xiaochuan X; Wang, Haijun H; You, Yongping Y; Yu, Hualin H; Yue, Shuyuan S; Zhang, Jianming J; Zhang, Xiaohua X; Wang, Shuo S; Mao, Ying Y; Zhong, Ping P; Gong, Ye Y; ,

Publication Date: 2022-08-20

Variant appearance in text: KLF4: 1225A>C; K409Q

PubMed Link: 36179152

Variant Present in the following documents:

• Main text
• cm9-135-1894.pdf

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CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience

Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X

Publication Date: 2022-09-16

Variant appearance in text: KLF4: K409Q

PubMed Link: 36117989

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

View BVdb publication page

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Comprehensive germline and somatic genomic profiles of Chinese patients with biliary tract cancer.

Frontiers In Oncology

Yu, Haipeng H; Xu, Yan Y; Gao, Wei W; Li, Mei M; He, Ji'an J; Deng, Xiaoqian X; Xing, Wenge W

Publication Date: 2022

Variant appearance in text: KLF4: K409Q

PubMed Link: 36072793

Variant Present in the following documents:

• Table_3.xlsx, sheet 1

View BVdb publication page

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Mutated KLF4(K409Q) in meningioma binds STRs and activates FGF3 gene expression.

Iscience

Tsytsykova, Alla V AV; Wiley, Graham G; Li, Chuang C; Pelikan, Richard C RC; Garman, Lori L; Acquah, Francis A FA; Mooers, Blaine H M BHM; Tsitsikov, Erdyni N EN; Dunn, Ian F IF

Publication Date: 2022-08-19

Variant appearance in text: KLF4: K409Q

PubMed Link: 35996584

Variant Present in the following documents:

• Main text
• mmc1.pdf
• main.pdf

View BVdb publication page

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Single-cell DNA sequencing reveals order of mutational acquisition in TRAF7/AKT1 and TRAF7/KLF4 mutant meningiomas.

Acta Neuropathologica

Dogan, Helin H; Blume, Christina C; Patel, Areeba A; Jungwirth, Gerhard G; Sogerer, Lisa L; Ratliff, Miriam M; Ketter, Ralf R; Herold-Mende, Christel C; Jones, David T W DTW; Wick, Wolfgang W; Vollmuth, Philipp P; Zweckberger, Klaus K; Reuss, David D; von Deimling, Andreas A; Sahm, Felix F

Publication Date: 2022-10

Variant appearance in text: KLF4: K409Q

PubMed Link: 35984495

Variant Present in the following documents:

• 401_2022_2485_MOESM4_ESM.xlsx, sheet 1
• 401_2022_2485_MOESM6_ESM.xlsx, sheet 1
• 401_2022_2485_MOESM4_ESM.xlsx, sheet 2

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Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications

Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A

Publication Date: 2022-07-13

Variant appearance in text: KLF4: 1225A>C; K409Q

PubMed Link: 35831314

Variant Present in the following documents:

• 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3

View BVdb publication page

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NF2 Alteration/22q Loss Is Associated with Recurrence in WHO Grade 1 Sphenoid Wing Meningiomas.

Cancers

Sakai, Yu Y; Miyawaki, Satoru S; Teranishi, Yu Y; Okano, Atsushi A; Ohara, Kenta K; Hongo, Hiroki H; Ishigami, Daiichiro D; Shimada, Daisuke D; Mitsui, Jun J; Nakatomi, Hirofumi H; Saito, Nobuhito N

Publication Date: 2022-06-29

Variant appearance in text: KLF4: K409Q

PubMed Link: 35804955

Variant Present in the following documents:

• Main text
• cancers-14-03183.pdf

View BVdb publication page

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Clinicopathologic Characteristics of Grade 2/3 Meningiomas: A Perspective on the Role of Next-Generation Sequencing.

Frontiers In Oncology

Kim, Junhyung J; Hwang, Kihwan K; Kwon, Hyun Jung HJ; Lee, Ji Eun JE; Lee, Kyu Sang KS; Choe, Gheeyoung G; Han, Jung Ho JH; Kim, Chae-Yong CY

Publication Date: 2022

Variant appearance in text: KLF4: 1225A>C; K409Q

PubMed Link: 35774130

Variant Present in the following documents:

• Main text
• fonc-12-885155.pdf

View BVdb publication page

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Potential Molecular Mechanisms of Recurrent and Progressive Meningiomas: A Review of the Latest Literature.

Frontiers In Oncology

Peng, Wenjie W; Wu, Pei P; Yuan, Minghao M; Yuan, Bo B; Zhu, Lian L; Zhou, Jiesong J; Li, Qian Q

Publication Date: 2022

Variant appearance in text: KLF4: K409Q

PubMed Link: 35712491

Variant Present in the following documents:

• fonc-12-850463.pdf

View BVdb publication page

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A Comprehensive Survey of Genomic Mutations in Breast Cancer Reveals Recurrent Neoantigens as Potential Therapeutic Targets.

Frontiers In Oncology

Zhou, Si S; Liu, Songming S; Zhao, Lijian L; Sun, Hai-Xi HX

Publication Date: 2022

Variant appearance in text: KLF4: K409Q

PubMed Link: 35387130

Variant Present in the following documents:

• Table_2.xlsx, sheet 1

View BVdb publication page

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Prognostic impact of genetic alterations and methylation classes in meningioma.

Brain Pathology (Zurich, Switzerland)

Berghoff, Anna S AS; Hielscher, Thomas T; Ricken, Gerda G; Furtner, Julia J; Schrimpf, Daniel D; Widhalm, Georg G; Rajky, Ursula U; Marosi, Christine C; Hainfellner, Johannes A JA; von Deimling, Andreas A; Sahm, Felix F; Preusser, Matthias M

Publication Date: 2022-03

Variant appearance in text: KLF4: K409Q

PubMed Link: 35213082

Variant Present in the following documents:

• BPA-32-e12970-s001.xlsx, sheet 1

View BVdb publication page

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A new amplicon-based gene panel for next generation sequencing characterization of meningiomas.

Brain Pathology (Zurich, Switzerland)

Mawrin, Christian C; Koch, Ralf R; Waldt, Natalie N; Sandalcioglu, I Erol IE; Braunsdorf, Werner E K WEK; Warnke, Jan-Peter JP; Goehre, Felix F; Meisel, Hans-Jürgen HJ; Ewald, Christian C; Neyazi, Sina S; Schüller, Ulrich U; Kirches, Elmar E

Publication Date: 2022-03

Variant appearance in text: KLF4: K409Q

PubMed Link: 35213080

Variant Present in the following documents:

• Main text
• BPA-32-e13046.pdf

View BVdb publication page

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Tumor-Derived Cell Culture Model for the Investigation of Meningioma Biology.

Journal Of Neuropathology And Experimental Neurology

Uhlmann, Erik J EJ; Rabinovsky, Rosalia R; Varma, Hemant H; El Fatimy, Rachid R; Kasper, Ekkehard M EM; Moore, Justin M JM; Vega, Rafael A RA; Thomas, Ajith J AJ; Alterman, Ronald L RL; Stippler, Martina M; Anderson, Matthew P MP; Uhlmann, Erik N EN; Kipper, Franciela C FC; Krichevsky, Anna M AM

Publication Date: 2021-11-28

Variant appearance in text: KLF4: K409Q

PubMed Link: 34850056

Variant Present in the following documents:

• Main text

View BVdb publication page

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The integrated multiomic diagnosis of sporadic meningiomas: a review of its clinical implications.

Journal Of Neuro-Oncology

Robert, Stephanie M SM; Vetsa, Shaurey S; Nadar, Arushii A; Vasandani, Sagar S; Youngblood, Mark W MW; Gorelick, Evan E; Jin, Lan L; Marianayanam, Neelan N; Erson-Omay, E Zeynep EZ; Günel, Murat M; Moliterno, Jennifer J

Publication Date: 2021-11-30

Variant appearance in text: KLF4: K409Q

PubMed Link: 34846640

Variant Present in the following documents:

• Main text
• 11060_2021_Article_3874.pdf

View BVdb publication page

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The integrated multiomic diagnosis of sporadic meningiomas: a review of its clinical implications.

Journal Of Neuro-Oncology

Robert, Stephanie M SM; Vetsa, Shaurey S; Nadar, Arushii A; Vasandani, Sagar S; Youngblood, Mark W MW; Gorelick, Evan E; Jin, Lan L; Marianayagam, Neelan N; Erson-Omay, E Zeynep EZ; Günel, Murat M; Moliterno, Jennifer J

Publication Date: 2022-01

Variant appearance in text: KLF4: K409Q

PubMed Link: 34846640

Variant Present in the following documents:

• Main text
• 11060_2021_Article_3874.pdf

View BVdb publication page

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Discovering the Molecular Landscape of Meningioma: The Struggle to Find New Therapeutic Targets.

Diagnostics (Basel, Switzerland)

Maggio, Ilaria I; Franceschi, Enrico E; Di Nunno, Vincenzo V; Gatto, Lidia L; Tosoni, Alicia A; Angelini, Daniele D; Bartolini, Stefania S; Lodi, Raffaele R; Brandes, Alba Ariela AA

Publication Date: 2021-10-08

Variant appearance in text: KLF4: K409Q

PubMed Link: 34679551

Variant Present in the following documents:

• Main text
• diagnostics-11-01852.pdf

View BVdb publication page

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Genomic Biomarkers of Meningioma: A Focused Review.

International Journal Of Molecular Sciences

Pawloski, Jacob A JA; Fadel, Hassan A HA; Huang, Yi-Wen YW; Lee, Ian Y IY

Publication Date: 2021-09-23

Variant appearance in text: KLF4: K409Q

PubMed Link: 34638590

Variant Present in the following documents:

• ijms-22-10222.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: KLF4: K409Q

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology

Maas, Sybren L N SLN; Stichel, Damian D; Hielscher, Thomas T; Sievers, Philipp P; Berghoff, Anna S AS; Schrimpf, Daniel D; Sill, Martin M; Euskirchen, Philipp P; Blume, Christina C; Patel, Areeba A; Dogan, Helin H; Reuss, David D; Dohmen, Hildegard H; Stein, Marco M; Reinhardt, Annekathrin A; Suwala, Abigail K AK; Wefers, Annika K AK; Baumgarten, Peter P; Ricklefs, Franz F; Rushing, Elisabeth J EJ; Bewerunge-Hudler, Melanie M; Ketter, Ralf R; Schittenhelm, Jens J; Jaunmuktane, Zane Z; Leu, Severina S; Greenway, Fay E A FEA; Bridges, Leslie R LR; Jones, Timothy T; Grady, Conor C; Serrano, Jonathan J; Golfinos, John J; Sen, Chandra C; Mawrin, Christian C; Jungk, Christine C; Hänggi, Daniel D; Westphal, Manfred M; Lamszus, Katrin K; Etminan, Nima N; Jungwirth, Gerhard G; Herold-Mende, Christel C; Unterberg, Andreas A; Harter, Patrick N PN; Wirsching, Hans-Georg HG; Neidert, Marian C MC; Ratliff, Miriam M; Platten, Michael M; Snuderl, Matija M; Aldape, Kenneth D KD; Brandner, Sebastian S; Hench, Jürgen J; Frank, Stephan S; Pfister, Stefan M SM; Jones, David T W DTW; Reifenberger, Guido G; Acker, Till T; Wick, Wolfgang W; Weller, Michael M; Preusser, Matthias M; von Deimling, Andreas A; Sahm, Felix F; ,

Publication Date: 2021-12-01

Variant appearance in text: KLF4: K409Q

PubMed Link: 34618539

Variant Present in the following documents:

• jco-39-3839.pdf

View BVdb publication page

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Molecular profiling of pediatric meningiomas shows tumor characteristics distinct from adult meningiomas.

Acta Neuropathologica

Kirches, Elmar E; Sahm, Felix F; Korshunov, Andrey A; Bluecher, Christina C; Waldt, Natalie N; Kropf, Siegfried S; Schrimpf, Daniel D; Sievers, Philipp P; Stichel, Damian D; Schüller, Ulrich U; Schittenhelm, Jens J; Riemenschneider, Markus J MJ; Karajannis, Matthias A MA; Perry, Arie A; Pietsch, Torsten T; Boekhoff, Svenja S; Capper, David D; Beck, Katja K; Paramasivam, Nagarajan N; Schlesner, Matthias M; Brastianos, Priscilla K PK; Müller, Hermann L HL; Pfister, Stefan M SM; Mawrin, Christian C

Publication Date: 2021-11

Variant appearance in text: KLF4: K409Q

PubMed Link: 34495383

Variant Present in the following documents:

• Main text
• 401_2021_Article_2351.pdf

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Advances in Multidisciplinary Management of Skull Base Meningiomas.

Cancers

Ius, Tamara T; Tel, Alessandro A; Minniti, Giuseppe G; Somma, Teresa T; Solari, Domenico D; Longhi, Michele M; De Bonis, Pasquale P; Scerrati, Alba A; Caccese, Mario M; Barresi, Valeria V; Fiorentino, Alba A; Gorgoglione, Leonardo L; Lombardi, Giuseppe G; Robiony, Massimo M

Publication Date: 2021-05-28

Variant appearance in text: KLF4: K409Q

PubMed Link: 34071391

Variant Present in the following documents:

• Main text

View BVdb publication page

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Comprehensive omic characterization of breast cancer in Mexican-Hispanic women.

Nature Communications

Romero-Cordoba, Sandra L SL; Salido-Guadarrama, Ivan I; Rebollar-Vega, Rosa R; Bautista-Piña, Veronica V; Dominguez-Reyes, Carlos C; Tenorio-Torres, Alberto A; Villegas-Carlos, Felipe F; Fernández-López, Juan C JC; Uribe-Figueroa, Laura L; Alfaro-Ruiz, Luis L; Hidalgo-Miranda, Alfredo A

Publication Date: 2021-04-14

Variant appearance in text: KLF4: K409Q

PubMed Link: 33854067

Variant Present in the following documents:

• 41467_2021_22478_MOESM8_ESM.xlsx, sheet 7

View BVdb publication page

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Associations of pathological diagnosis and genetic abnormalities in meningiomas with the embryological origins of the meninges.

Scientific Reports

Okano, Atsushi A; Miyawaki, Satoru S; Hongo, Hiroki H; Dofuku, Shogo S; Teranishi, Yu Y; Mitsui, Jun J; Tanaka, Michihiro M; Shin, Masahiro M; Nakatomi, Hirofumi H; Saito, Nobuhito N

Publication Date: 2021-03-26

Variant appearance in text: KLF4: Lys409Gln

PubMed Link: 33772057

Variant Present in the following documents:

• Main text
• 41598_2021_Article_86298.pdf

View BVdb publication page

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Neurofibromatosis Type 2 (NF2) and the Implications for Vestibular Schwannoma and Meningioma Pathogenesis.

International Journal Of Molecular Sciences

Bachir, Suha S; Shah, Sanjit S; Shapiro, Scott S; Koehler, Abigail A; Mahammedi, Abdelkader A; Samy, Ravi N RN; Zuccarello, Mario M; Schorry, Elizabeth E; Sengupta, Soma S

Publication Date: 2021-01-12

Variant appearance in text: KLF4: K409Q

PubMed Link: 33445724

Variant Present in the following documents:

• ijms-22-00690.pdf

View BVdb publication page

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Sporadic multiple meningiomas harbor distinct driver mutations.

Acta Neuropathologica Communications

Juratli, Tareq A TA; Prilop, Insa I; Saalfeld, Felix C FC; Herold, Sylvia S; Meinhardt, Matthias M; Wenzel, Carina C; Zeugner, Silke S; Aust, Daniela E DE; Barker, Fred G FG; Cahill, Daniel P DP; Brastianos, Priscilla K PK; Santagata, Sandro S; Schackert, Gabriele G; Pinzer, Thomas T

Publication Date: 2021-01-06

Variant appearance in text: KLF4: K409Q

PubMed Link: 33407897

Variant Present in the following documents:

• Main text

View BVdb publication page

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Advances in meningioma genomics, proteomics, and epigenetics: insights into biomarker identification and targeted therapies.

Oncotarget

Nazem, Ahmad A AA; Ruzevick, Jacob J; Ferreira, Manuel J MJ

Publication Date: 2020-12-08

Variant appearance in text: KLF4: K409Q

PubMed Link: 33346248

Variant Present in the following documents:

• Main text

View BVdb publication page

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The spatial phenotype of genotypically distinct meningiomas demonstrate potential implications of the embryology of the meninges.

Oncogene

Fountain, Daniel M DM; Smith, Miriam J MJ; O'Leary, Claire C; Pathmanaban, Omar N ON; Roncaroli, Federico F; Bobola, Nicoletta N; King, Andrew T AT; Evans, Dafydd Gareth DG

Publication Date: 2021-02

Variant appearance in text: KLF4: Lys409Gln

PubMed Link: 33262459

Variant Present in the following documents:

• Main text
• 41388_2020_Article_1568.pdf

View BVdb publication page

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Occurrence of Fibrotic Tumor Vessels in Grade I Meningiomas Is Strongly Associated with Vessel Density, Expression of VEGF, PlGF, IGFBP-3 and Tumor Recurrence.

Cancers

Hess, Katharina K; Spille, Dorothee Cäcilia DC; Adeli, Alborz A; Sporns, Peter B PB; Zitta, Karina K; Hummitzsch, Lars L; Pfarr, Julian J; Stummer, Walter W; Brokinkel, Benjamin B; Berndt, Rouven R; Albrecht, Martin M

Publication Date: 2020-10-21

Variant appearance in text: KLF4: K409Q

PubMed Link: 33096816

Variant Present in the following documents:

• cancers-12-03075.pdf

View BVdb publication page

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Associations of meningioma molecular subgroup and tumor recurrence.

Neuro-Oncology

Youngblood, Mark W MW; Miyagishima, Danielle F DF; Jin, Lan L; Gupte, Trisha T; Li, Chang C; Duran, Daniel D; Montejo, Julio D JD; Zhao, Amy A; Sheth, Amar A; Tyrtova, Evgeniya E; Özduman, Koray K; Iacoangeli, Francesco F; Peyre, Matthieu M; Boetto, Julien J; Pease, Matthew M; Avşar, Timuçin T; Huttner, Anita A; Bilguvar, Kaya K; Kilic, Türker T; Pamir, M Necmettin MN; Amankulor, Nduka N; Kalamarides, Michel M; Erson-Omay, E Zeynep EZ; Günel, Murat M; Moliterno, Jennifer J

Publication Date: 2021-05-05

Variant appearance in text: KLF4: K409Q

PubMed Link: 33068421

Variant Present in the following documents:

• Main text

View BVdb publication page

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Sensitivity of human meningioma cells to the cyclin-dependent kinase inhibitor, TG02.

Translational Oncology

von Achenbach, Caroline C; Le Rhun, Emilie E; Sahm, Felix F; Wang, Sophie S SS; Sievers, Philipp P; Neidert, Marian C MC; Rushing, Elisabeth J EJ; Lawhon, Tracy T; Schneider, Hannah H; von Deimling, Andreas A; Weller, Michael M

Publication Date: 2020-12

Variant appearance in text: KLF4: K409Q

PubMed Link: 32916418

Variant Present in the following documents:

• main.pdf

View BVdb publication page

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Genomic characterization of malignant progression in neoplastic pancreatic cysts.

Nature Communications

Noë, Michaël M; Niknafs, Noushin N; Fischer, Catherine G CG; Hackeng, Wenzel M WM; Beleva Guthrie, Violeta V; Hosoda, Waki W; Debeljak, Marija M; Papp, Eniko E; Adleff, Vilmos V; White, James R JR; Luchini, Claudio C; Pea, Antonio A; Scarpa, Aldo A; Butturini, Giovanni G; Zamboni, Giuseppe G; Castelli, Paola P; Hong, Seung-Mo SM; Yachida, Shinichi S; Hiraoka, Nobuyoshi N; Gill, Anthony J AJ; Samra, Jaswinder S JS; Offerhaus, G Johan A GJA; Hoorens, Anne A; Verheij, Joanne J; Jansen, Casper C; Adsay, N Volkan NV; Jiang, Wei W; Winter, Jordan J; Albores-Saavedra, Jorge J; Terris, Benoit B; Thompson, Elizabeth D ED; Roberts, Nicholas J NJ; Hruban, Ralph H RH; Karchin, Rachel R; Scharpf, Robert B RB; Brosens, Lodewijk A A LAA; Velculescu, Victor E VE; Wood, Laura D LD

Publication Date: 2020-08-14

Variant appearance in text: KLF4: K409Q

PubMed Link: 32796935

Variant Present in the following documents:

• 41467_2020_17917_MOESM7_ESM.xlsx, sheet 1

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Comparative clinical and genomic analysis of neurofibromatosis type 2-associated cranial and spinal meningiomas.

Scientific Reports

Pemov, Alexander A; Dewan, Ramita R; Hansen, Nancy F NF; Chandrasekharappa, Settara C SC; Ray-Chaudhury, Abhik A; Jones, Kristine K; Luo, Wen W; Heiss, John D JD; Mullikin, James C JC; Chittiboina, Prashant P; Stewart, Douglas R DR; Asthagiri, Ashok R AR

Publication Date: 2020-07-28

Variant appearance in text: KLF4: K409Q

PubMed Link: 32724039

Variant Present in the following documents:

• 41598_2020_Article_69074.pdf

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Brief CommunicationCirculating tumor DNA is present in the most aggressive meningiomas.

Neuro-Oncology Advances

Graillon, Thomas T; Roche, Catherine C; Basset, Noémie N; Mougel, Gregory G; Meyer, Mikael M; Farah, Kaissar K; Boissonneau, Sébastien S; Fuentes, Stéphane S; Tabouret, Emeline E; Campello, Chantal C; Appay, Romain R; Figarella-Branger, Dominique D; Chinot, Olivier O; Dufour, Henry H; Romanet, Pauline P; Barlier, Anne A

Publication Date: 2020

Variant appearance in text: KLF4: 1225A>C; Lys409Gln

PubMed Link: 32642718

Variant Present in the following documents:

• Main text
• vdaa068.pdf

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mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports

Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM

Publication Date: 2020-06-23

Variant appearance in text: KLF4: K409Q

PubMed Link: 32579932

Variant Present in the following documents:

• mmc5.xlsx, sheet 3

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KLF4K409Q-mutated meningiomas show enhanced hypoxia signaling and respond to mTORC1 inhibitor treatment.

Acta Neuropathologica Communications

von Spreckelsen, Niklas N; Waldt, Natalie N; Poetschke, Rebecca R; Kesseler, Christoph C; Dohmen, Hildegard H; Jiao, Hui-Ke HK; Nemeth, Attila A; Schob, Stefan S; Scherlach, Cordula C; Sandalcioglu, Ibrahim Erol IE; Deckert, Martina M; Angenstein, Frank F; Krischek, Boris B; Stavrinou, Pantelis P; Timmer, Marco M; Remke, Marc M; Kirches, Elmar E; Goldbrunner, Roland R; Chiocca, E Antonio EA; Huettelmaier, Stefan S; Acker, Till T; Mawrin, Christian C

Publication Date: 2020-04-03

Variant appearance in text: KLF4: K409Q

PubMed Link: 32245394

Variant Present in the following documents:

• Main text
• 40478_2020_Article_912.pdf

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: KLF4: K409Q

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

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A Rapid Robust Method for Subgrouping Non-NF2 Meningiomas According to Genotype and Detection of Lower Levels of M2 Macrophages in AKT1 E17K Mutated Tumours.

International Journal Of Molecular Sciences

Adams, Claire L CL; Ercolano, Emanuela E; Ferluga, Sara S; Sofela, Agbolahan A; Dave, Foram F; Negroni, Caterina C; Kurian, Kathreena M KM; Hilton, David A DA; Hanemann, C Oliver CO

Publication Date: 2020-02-13

Variant appearance in text: KLF4: K409Q

PubMed Link: 32070062

Variant Present in the following documents:

• Main text

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Recent Advances in Meningioma Immunogenetics.

Frontiers In Oncology

Al-Rashed, May M; Foshay, Kara K; Abedalthagafi, Malak M

Publication Date: 2019

Variant appearance in text: KLF4: K409Q

PubMed Link: 31970090

Variant Present in the following documents:

• Main text

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Molecular characteristics of meningiomas.

Journal Of Pathology And Translational Medicine

Lee, Young Suk YS; Lee, Youn Soo YS

Publication Date: 2020-01

Variant appearance in text: KLF4: Lys409Gln

PubMed Link: 31964111

Variant Present in the following documents:

• Main text
• jptm-2019-11-05.pdf

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