Publications:

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Toll-Like Receptor 4: A Promising Therapeutic Target for Alzheimer's Disease.

Mediators Of Inflammation

Wu, Linyu L; Xian, Xiaohui X; Xu, Guangyu G; Tan, Zixuan Z; Dong, Fang F; Zhang, Min M; Zhang, Feng F

Publication Date: 2022

Variant appearance in text: rs12377632

PubMed Link: 36046763

Variant Present in the following documents:

• MI2022-7924199.pdf

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Asian Race and Primary Open-Angle Glaucoma: Where Do We Stand?

Journal Of Clinical Medicine

Belamkar, Aditya A; Harris, Alon A; Oddone, Francesco F; Verticchio Vercellin, Alice A; Fabczak-Kubicka, Anna A; Siesky, Brent B

Publication Date: 2022-04-28

Variant appearance in text: rs12377632

PubMed Link: 35566612

Variant Present in the following documents:

• jcm-11-02486.pdf

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Association of toll-like receptors single nucleotide polymorphisms with HBV and HCV infection: research status.

Peerj

Xu, Yaxin Y; Xue, Wentao W; Gao, Hongwei H; Cui, Jiabo J; Zhao, Lingzhi L; You, Chongge C

Publication Date: 2022

Variant appearance in text: rs12377632

PubMed Link: 35462764

Variant Present in the following documents:

• Main text
• peerj-10-13335.pdf

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Toll-Like Receptors (TLRs): Structure, Functions, Signaling, and Role of Their Polymorphisms in Colorectal Cancer Susceptibility.

Biomed Research International

Sameer, Aga Syed AS; Nissar, Saniya S

Publication Date: 2021

Variant appearance in text: rs12377632

PubMed Link: 34552981

Variant Present in the following documents:

• Main text
• BMRI2021-1157023.pdf

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Germline Genetic Variants of Viral Entry and Innate Immunity May Influence Susceptibility to SARS-CoV-2 Infection: Toward a Polygenic Risk Score for Risk Stratification.

Frontiers In Immunology

Grolmusz, Vince Kornél VK; Bozsik, Anikó A; Papp, János J; Patócs, Attila A

Publication Date: 2021

Variant appearance in text: rs12377632

PubMed Link: 33763088

Variant Present in the following documents:

• Main text

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Innate and Adaptive Gene Single Nucleotide Polymorphisms Associated With Susceptibility of Severe Inflammatory Complications in Acanthamoeba Keratitis.

Investigative Ophthalmology & Visual Science

Carnt, Nicole A NA; Pang, Ignatius I; Burdon, Kathryn P KP; Calder, Virginia V; Dart, John K JK; Subedi, Dinesh D; Hardcastle, Alison J AJ

Publication Date: 2021-03-01

Variant appearance in text: rs12377632

PubMed Link: 33755043

Variant Present in the following documents:

• Main text
• iovs-62-3-33.pdf

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TLR4 Targeting as a Promising Therapeutic Strategy for Alzheimer Disease Treatment.

Frontiers In Neuroscience

Zhou, Yongji Y; Chen, Yanxing Y; Xu, Congcong C; Zhang, Hao H; Lin, Caixiu C

Publication Date: 2020

Variant appearance in text: rs12377632

PubMed Link: 33390886

Variant Present in the following documents:

• Main text
• fnins-14-602508.pdf

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Polymorphisms of TLR2, TLR4 and TOLLIP and tuberculosis in two independent studies.

Bioscience Reports

Wu, Shouquan S; Liu, Xiangmin X; Chen, Ling L; Wang, Yu Y; Zhang, Miaomiao M; Wang, Minggui M; He, Jian-Qing JQ

Publication Date: 2020-08-28

Variant appearance in text: rs12377632

PubMed Link: 32648572

Variant Present in the following documents:

• Main text

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Fibronectin extra domain A (FN-EDA) elevates intraocular pressure through Toll-like receptor 4 signaling.

Scientific Reports

Roberts, Amanda L AL; Mavlyutov, Timur A TA; Perlmutter, Tanisha E TE; Curry, Stacy M SM; Harris, Sherri L SL; Chauhan, Anil K AK; McDowell, Colleen M CM

Publication Date: 2020-06-17

Variant appearance in text: rs12377632

PubMed Link: 32555351

Variant Present in the following documents:

• Main text
• 41598_2020_Article_66756.pdf

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Genomics of Otitis Media (OM): Molecular Genetics Approaches to Characterize Disease Pathophysiology.

Frontiers In Genetics

Giese, Arnaud P J APJ; Ali, Saadat S; Isaiah, Amal A; Aziz, Ishrat I; Riazuddin, Saima S; Ahmed, Zubair M ZM

Publication Date: 2020

Variant appearance in text: rs12377632

PubMed Link: 32391049

Variant Present in the following documents:

• Main text
• fgene-11-00313.pdf

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Associations between TLR4 Polymorphisms and Open Angle Glaucoma: A Meta-Analysis.

Biomed Research International

Lin, Zhongjing Z; Huang, Shouyue S; Sun, Jun J; Xie, Bing B; Zhong, Yisheng Y

Publication Date: 2019

Variant appearance in text: rs12377632

PubMed Link: 31428642

Variant Present in the following documents:

• Main text
• BMRI2019-6707650.pdf

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The association of toll-like receptor 4 gene polymorphisms with primary open angle glaucoma susceptibility: a meta-analysis.

Bioscience Reports

Chaiwiang, Narttaya N; Poyomtip, Teera T

Publication Date: 2019-04-30

Variant appearance in text: rs12377632

PubMed Link: 30877182

Variant Present in the following documents:

• Main text
• bsr-39-bsr20190029.pdf

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Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis.

Bmc Medical Genetics

Sode, Jacob J; Bank, Steffen S; Vogel, Ulla U; Andersen, Paal Skytt PS; Sørensen, Signe Bek SB; Bojesen, Anders Bo AB; Andersen, Malene Rohr MR; Brandslund, Ivan I; Dessau, Ram Benny RB; Hoffmann, Hans Jürgen HJ; Glintborg, Bente B; Hetland, Merete Lund ML; Locht, Henning H; Heegaard, Niels Henrik NH; Andersen, Vibeke V

Publication Date: 2018-09-12

Variant appearance in text: rs12377632

PubMed Link: 30208882

Variant Present in the following documents:

• Main text
• 12881_2018_Article_680.pdf

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Genetic variations in the TLR3 locus are associated with eosinophilic esophagitis.

United European Gastroenterology Journal

Ávila-Castellano, Robledo R; García-Lozano, José-Raúl JR; Cimbollek, Stefan S; Lucendo, Alfredo J AJ; Bozada, Juan-Manuel JM; Quiralte, Joaquín J

Publication Date: 2018-04

Variant appearance in text: rs12377632

PubMed Link: 29774148

Variant Present in the following documents:

• Main text

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The association analysis of TLR2 and TLR4 gene with tuberculosis in the Tibetan Chinese population.

Oncotarget

Xue, Xin X; Qiu, Yi Y; Jiang, Dong D; Jin, Tianbo T; Yan, Mengdan M; Zhu, Xikang X; Chu, Yonglie Y

Publication Date: 2017-12-22

Variant appearance in text: rs12377632

PubMed Link: 29348888

Variant Present in the following documents:

• Main text
• oncotarget-08-113082.pdf

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Genetic polymorphism related to monocyte-macrophage function is associated with graft-versus-host disease.

Scientific Reports

Hyvärinen, Kati K; Ritari, Jarmo J; Koskela, Satu S; Niittyvuopio, Riitta R; Nihtinen, Anne A; Volin, Liisa L; Gallardo, David D; Partanen, Jukka J

Publication Date: 2017-11-15

Variant appearance in text: rs12377632

PubMed Link: 29142307

Variant Present in the following documents:

• Main text
• 41598_2017_Article_15915.pdf

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Genetic dissection of host immune response in pneumonia development and progression.

Scientific Reports

Smelaya, Tamara V TV; Belopolskaya, Olesya B OB; Smirnova, Svetlana V SV; Kuzovlev, Artem N AN; Moroz, Viktor V VV; Golubev, Arkadiy M AM; Pabalan, Noel A NA; Salnikova, Lyubov E LE

Publication Date: 2016-10-11

Variant appearance in text: rs12377632

PubMed Link: 27725770

Variant Present in the following documents:

• srep35021-s1.pdf

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The role of genetics and antibodies in sepsis.

Annals Of Translational Medicine

Giamarellos-Bourboulis, Evangelos J EJ; Opal, Steven M SM

Publication Date: 2016-09

Variant appearance in text: rs12377632

PubMed Link: 27713886

Variant Present in the following documents:

• Main text

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Glaucoma Risk Alleles in the Ocular Hypertension Treatment Study.

Ophthalmology

Scheetz, Todd E TE; Faga, Ben B; Ortega, Lizette L; Roos, Ben R BR; Gordon, Mae O MO; Kass, Michael A MA; Wang, Kai K; Fingert, John H JH

Publication Date: 2016-12

Variant appearance in text: rs12377632

PubMed Link: 27707548

Variant Present in the following documents:

• Main text

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Systematic review: genetic biomarkers associated with anti-TNF treatment response in inflammatory bowel diseases.

Alimentary Pharmacology & Therapeutics

Bek, S S; Nielsen, J V JV; Bojesen, A B AB; Franke, A A; Bank, S S; Vogel, U U; Andersen, V V

Publication Date: 2016-09

Variant appearance in text: rs12377632

PubMed Link: 27417569

Variant Present in the following documents:

• Main text
• APT-44-554.pdf

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Association between Genetic Polymorphisms and Response to Anti-TNFs in Patients with Inflammatory Bowel Disease.

International Journal Of Molecular Sciences

Prieto-Pérez, Rocío R; Almoguera, Berta B; Cabaleiro, Teresa T; Hakonarson, Hakon H; Abad-Santos, Francisco F

Publication Date: 2016-02-06

Variant appearance in text: rs12377632

PubMed Link: 26861312

Variant Present in the following documents:

• Main text

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Molecular Regulation of Toll-like Receptors in Asthma and COPD.

Frontiers In Physiology

Zuo, Li L; Lucas, Kurt K; Fortuna, Christopher A CA; Chuang, Chia-Chen CC; Best, Thomas M TM

Publication Date: 2015

Variant appearance in text: rs12377632

PubMed Link: 26617525

Variant Present in the following documents:

• Main text
• fphys-06-00312.pdf

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The association of polymorphisms of TLR4 and CD14 genes with susceptibility to sepsis in a Chinese population.

Bmc Medical Genetics

Wang, Haiyan H; Wei, Yesheng Y; Zeng, Yi Y; Qin, Yueqiu Y; Xiong, Bin B; Qin, Gang G; Li, Jun J; Hu, Donghai D; Qiu, Xiaowen X; Sooranna, Suren R SR; Pinhu, Liao L

Publication Date: 2014-11-14

Variant appearance in text: rs12377632

PubMed Link: 25394369

Variant Present in the following documents:

• Main text
• 12881_2014_Article_123.pdf

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Polymorphisms in the inflammatory pathway genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG are associated with susceptibility of inflammatory bowel disease in a Danish cohort.

Plos One

Bank, Steffen S; Skytt Andersen, Paal P; Burisch, Johan J; Pedersen, Natalia N; Roug, Stine S; Galsgaard, Julie J; Ydegaard Turino, Stine S; Brodersen, Jacob Broder JB; Rashid, Shaista S; Kaiser Rasmussen, Britt B; Avlund, Sara S; Bastholm Olesen, Thomas T; Jürgen Hoffmann, Hans H; Kragh Thomsen, Marianne M; Ostergaard Thomsen, Vibeke V; Frydenberg, Morten M; Andersen Nexø, Bjørn B; Sode, Jacob J; Vogel, Ulla U; Andersen, Vibeke V

Publication Date: 2014

Variant appearance in text: rs12377632

PubMed Link: 24971461

Variant Present in the following documents:

• Main text

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Anti-TNF treatment response in rheumatoid arthritis patients is associated with genetic variation in the NLRP3-inflammasome.

Plos One

Sode, Jacob J; Vogel, Ulla U; Bank, Steffen S; Andersen, Paal Skytt PS; Thomsen, Marianne Kragh MK; Hetland, Merete Lund ML; Locht, Henning H; Heegaard, Niels H H NH; Andersen, Vibeke V

Publication Date: 2014

Variant appearance in text: rs12377632

PubMed Link: 24967817

Variant Present in the following documents:

• Main text
• pone.0100361.pdf

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Toll-like receptor (TLR2 and TLR4) polymorphisms and chronic obstructive pulmonary disease.

Plos One

Budulac, Simona E SE; Boezen, H Marike HM; Hiemstra, Pieter S PS; Lapperre, Therese S TS; Vonk, Judith M JM; Timens, Wim W; Postma, Dirkje S DS; ,

Publication Date: 2012

Variant appearance in text: rs12377632

PubMed Link: 22952638

Variant Present in the following documents:

• Main text
• pone.0043124.pdf

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Are Toll-like receptor gene polymorphisms associated with prostate cancer?

Cancer Management And Research

Kutikhin, Anton G AG; Yuzhalin, Arseniy E AE

Publication Date: 2012

Variant appearance in text: rs12377632

PubMed Link: 22359464

Variant Present in the following documents:

• Main text

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The association of Toll-like receptor 4 gene polymorphisms with the development of emphysema in Japanese subjects: a case control study.

Bmc Research Notes

Ito, Michiko M; Hanaoka, Masayuki M; Droma, Yunden Y; Kobayashi, Nobumitsu N; Yasuo, Masanori M; Kitaguchi, Yoshiaki Y; Horiuchi, Toshimichi T; Ikegawa, Kayoko K; Katsuyama, Yoshihiko Y; Kubo, Keishi K; Ota, Masao M

Publication Date: 2012-01-18

Variant appearance in text: rs12377632

PubMed Link: 22251849

Variant Present in the following documents:

• Main text

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Toll-like receptor 4 gene polymorphisms do not associate with normal tension glaucoma in a Korean population.

Molecular Vision

Suh, Wool W; Kim, Sungmin S; Ki, Chang-Seok CS; Kee, Changwon C

Publication Date: 2011

Variant appearance in text: rs12377632

PubMed Link: 21921986

Variant Present in the following documents:

• Main text

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Toll-like receptor genes and their association with colon and rectal cancer development and prognosis.

International Journal Of Cancer

Slattery, Martha L ML; Herrick, Jennifer S JS; Bondurant, Kristina L KL; Wolff, Roger K RK

Publication Date: 2012-06-15

Variant appearance in text: rs12377632

PubMed Link: 21792899

Variant Present in the following documents:

• Main text

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Single nucleotide polymorphisms of Toll-like receptor 4 decrease the risk of development of hepatocellular carcinoma.

Plos One

Minmin, Shi S; Xiaoqian, Xu X; Hao, Chen C; Baiyong, Shen S; Xiaxing, Deng D; Junjie, Xie X; Xi, Zhan Z; Jianquan, Zhao Z; Songyao, Jiang J

Publication Date: 2011-04-29

Variant appearance in text: rs12377632

PubMed Link: 21559380

Variant Present in the following documents:

• Main text
• pone.0019466.pdf

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Lack of association between toll-like receptor 4 gene polymorphisms and sarcoidosis-related uveitis in Japan.

Molecular Vision

Asukata, Yuri Y; Ota, Masao M; Meguro, Akira A; Katsuyama, Yoshihiko Y; Ishihara, Mami M; Namba, Kenichi K; Kitaichi, Nobuyoshi N; Morimoto, Shin-Ichiro S; Kaburaki, Toshikatsu T; Ando, Yasutaka Y; Takenaka, Shinobu S; Inoko, Hidetoshi H; Ohno, Shigeaki S; Mizuki, Nobuhisa N

Publication Date: 2009-12-10

Variant appearance in text: rs12377632

PubMed Link: 20011079

Variant Present in the following documents:

• Main text
• mv-v15-2673.pdf

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Association of SLC11A1 with tuberculosis and interactions with NOS2A and TLR2 in African-Americans and Caucasians.

The International Journal Of Tuberculosis And Lung Disease : The Official Journal Of The International Union Against Tuberculosis And Lung Disease

Velez, D R DR; Hulme, W F WF; Myers, J L JL; Stryjewski, M E ME; Abbate, E E; Estevan, R R; Patillo, S G SG; Gilbert, J R JR; Hamilton, C D CD; Scott, W K WK

Publication Date: 2009-09

Variant appearance in text: rs12377632

PubMed Link: 19723394

Variant Present in the following documents:

• Main text

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