N-ethyl-N-nitrosourea-induced mutation in ubiquitin-specific peptidase 18 causes hyperactivation of IFN-αß signaling and suppresses STAT4-induced IFN-γ production, resulting in increased susceptibility to Salmonella typhimurium.
Journal Of Immunology (Baltimore, Md. : 1950)
Richer, Etienne E; Prendergast, Caitlin C; Zhang, Dong-Er DE; Qureshi, Salman T ST; Vidal, Silvia M SM; Malo, Danielle D