TLR4 c.269T>A ;(p.I90N)

Variant ID: 9-120474675-T-A

NM_138554.4(TLR4):c.269T>A;(p.I90N)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Forward genetic dissection of innate response to infection in inbred mouse strains: selected success stories.

Clinical And Experimental Immunology
Gruenheid, S S; Gros, P P
Publication Date: 2010-12

Variant appearance in text: TLR-4: I90N
PubMed Link: 21070206
Variant Present in the following documents:
  • Main text
View BVdb publication page



N-ethyl-N-nitrosourea-induced mutation in ubiquitin-specific peptidase 18 causes hyperactivation of IFN-αß signaling and suppresses STAT4-induced IFN-γ production, resulting in increased susceptibility to Salmonella typhimurium.

Journal Of Immunology (Baltimore, Md. : 1950)
Richer, Etienne E; Prendergast, Caitlin C; Zhang, Dong-Er DE; Qureshi, Salman T ST; Vidal, Silvia M SM; Malo, Danielle D
Publication Date: 2010-09-15

Variant appearance in text: TLR4: I90N
PubMed Link: 20693420
Variant Present in the following documents:
  • Main text
View BVdb publication page