Publications:

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Differential plasma proteomes of the patients with Opisthorchiasis viverrini and cholangiocarcinoma identify a polymeric immunoglobulin receptor as a potential biomarker.

Heliyon

Prasopdee, Sattrachai S; Yingchutrakul, Yodying Y; Krobthong, Sucheewin S; Pholhelm, Montinee M; Wongtrakoongate, Patompon P; Butthongkomvong, Kritiya K; Kulsantiwong, Jutharat J; Phanaksri, Teva T; Kunjantarachot, Anthicha A; Sathavornmanee, Thanakrit T; Tesana, Smarn S; Thitapakorn, Veerachai V

Publication Date: 2022-10

Variant appearance in text: TLR4: R196C

PubMed Link: 36247154

Variant Present in the following documents:

• mmc3.pdf

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Structural Evolution of TIR-Domain Signalosomes.

Frontiers In Immunology

Nimma, Surekha S; Gu, Weixi W; Maruta, Natsumi N; Li, Yan Y; Pan, Mengqi M; Saikot, Forhad Karim FK; Lim, Bryan Y J BYJ; McGuinness, Helen Ying HY; Zaoti, Zannati Ferdous ZF; Li, Sulin S; Desa, Sneha S; Manik, Mohammad Kawsar MK; Nanson, Jeffrey D JD; Kobe, Bostjan B

Publication Date: 2021

Variant appearance in text: TLR4: R196C

PubMed Link: 34868065

Variant Present in the following documents:

• Main text
• fimmu-12-784484.pdf

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Toll-Like Receptor Signaling in the Establishment and Function of the Immune System.

Cells

Aluri, Jahnavi J; Cooper, Megan A MA; Schuettpelz, Laura G LG

Publication Date: 2021-06-02

Variant appearance in text: TLR4: R196C

PubMed Link: 34199501

Variant Present in the following documents:

• Main text
• cells-10-01374.pdf

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Development of a Novel Backbone Cyclic Peptide Inhibitor of the Innate Immune TLR/IL1R Signaling Protein MyD88.

Scientific Reports

Dishon, Shira S; Schumacher, Adi A; Fanous, Joseph J; Talhami, Alaa A; Kassis, Ibrahim I; Karussis, Dimitrios D; Gilon, Chaim C; Hoffman, Amnon A; Nussbaum, Gabriel G

Publication Date: 2018-06-21

Variant appearance in text: TLR4: R196C

PubMed Link: 29930295

Variant Present in the following documents:

• Main text
• 41598_2018_Article_27773.pdf

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Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma.

Nature Communications

Lauss, Martin M; Donia, Marco M; Harbst, Katja K; Andersen, Rikke R; Mitra, Shamik S; Rosengren, Frida F; Salim, Maryem M; Vallon-Christersson, Johan J; Törngren, Therese T; Kvist, Anders A; Ringnér, Markus M; Svane, Inge Marie IM; Jönsson, Göran G

Publication Date: 2017-11-23

Variant appearance in text: TLR4: R196C

PubMed Link: 29170503

Variant Present in the following documents:

• 41467_2017_1460_MOESM6_ESM.xlsx, sheet 1

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Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling.

Nature Structural & Molecular Biology

Ve, Thomas T; Vajjhala, Parimala R PR; Hedger, Andrew A; Croll, Tristan T; DiMaio, Frank F; Horsefield, Shane S; Yu, Xiong X; Lavrencic, Peter P; Hassan, Zahid Z; Morgan, Garry P GP; Mansell, Ashley A; Mobli, Mehdi M; O'Carroll, Ailis A; Chauvin, Brieuc B; Gambin, Yann Y; Sierecki, Emma E; Landsberg, Michael J MJ; Stacey, Katryn J KJ; Egelman, Edward H EH; Kobe, Bostjan B

Publication Date: 2017-09

Variant appearance in text: TLR4: R196C

PubMed Link: 28759049

Variant Present in the following documents:

• Main text

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Toll-like receptors and human disease: lessons from single nucleotide polymorphisms.

Current Genomics

Lin, Yi-Tzu YT; Verma, Amanda A; Hodgkinson, Conrad P CP

Publication Date: 2012-12

Variant appearance in text: TLR4: Arg196Cys

PubMed Link: 23730203

Variant Present in the following documents:

• Main text
• CG-13-633.pdf

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Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Snyder, Greg A GA; Cirl, Christine C; Jiang, Jiansheng J; Chen, Kang K; Waldhuber, Anna A; Smith, Patrick P; Römmler, Franziska F; Snyder, Nathaniel N; Fresquez, Theresa T; Dürr, Susanne S; Tjandra, Nico N; Miethke, Thomas T; Xiao, Tsan Sam TS

Publication Date: 2013-04-23

Variant appearance in text: TLR4: R196C

PubMed Link: 23569230

Variant Present in the following documents:

• Main text

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TRAM is involved in IL-18 signaling and functions as a sorting adaptor for MyD88.

Plos One

Ohnishi, Hidenori H; Tochio, Hidehito H; Kato, Zenichiro Z; Kawamoto, Norio N; Kimura, Takeshi T; Kubota, Kazuo K; Yamamoto, Takahiro T; Funasaka, Tatsuyoshi T; Nakano, Hiroshi H; Wong, Richard W RW; Shirakawa, Masahiro M; Kondo, Naomi N

Publication Date: 2012

Variant appearance in text: TLR4: R196C

PubMed Link: 22685567

Variant Present in the following documents:

• Main text
• pone.0038423.pdf

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Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Valkov, Eugene E; Stamp, Anna A; Dimaio, Frank F; Baker, David D; Verstak, Brett B; Roversi, Pietro P; Kellie, Stuart S; Sweet, Matthew J MJ; Mansell, Ashley A; Gay, Nicholas J NJ; Martin, Jennifer L JL; Kobe, Bostjan B

Publication Date: 2011-09-06

Variant appearance in text: TLR4: R196C

PubMed Link: 21873236

Variant Present in the following documents:

• Main text

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Two human MYD88 variants, S34Y and R98C, interfere with MyD88-IRAK4-myddosome assembly.

The Journal Of Biological Chemistry

George, Julie J; Motshwene, Precious G PG; Wang, Hui H; Kubarenko, Andriy V AV; Rautanen, Anna A; Mills, Tara C TC; Hill, Adrian V S AV; Gay, Nicholas J NJ; Weber, Alexander N R AN

Publication Date: 2011-01-14

Variant appearance in text: TLR4: R196C

PubMed Link: 20966070

Variant Present in the following documents:

• Main text
• zbc1341.pdf

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Identification of critical residues of the MyD88 death domain involved in the recruitment of downstream kinases.

The Journal Of Biological Chemistry

Loiarro, Maria M; Gallo, Grazia G; Fantò, Nicola N; De Santis, Rita R; Carminati, Paolo P; Ruggiero, Vito V; Sette, Claudio C

Publication Date: 2009-10-09

Variant appearance in text: TLR4: R196C

PubMed Link: 19679662

Variant Present in the following documents:

• Main text

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Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Ohnishi, Hidenori H; Tochio, Hidehito H; Kato, Zenichiro Z; Orii, Kenji E KE; Li, Ailian A; Kimura, Takeshi T; Hiroaki, Hidekazu H; Kondo, Naomi N; Shirakawa, Masahiro M

Publication Date: 2009-06-23

Variant appearance in text: TLR4: R196C

PubMed Link: 19506249

Variant Present in the following documents:

• Main text

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