TLR4 c.1318_1319delinsGC ;(p.F440A)

Variant ID: 9-120475724-TT-GC

NM_138554.4(TLR4):c.1318_1319delinsGC;(p.F440A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Synergy between 15-lipoxygenase and secreted PLA2 promotes inflammation by formation of TLR4 agonists from extracellular vesicles.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Ha, Van Thai VT; Lainšček, Duško D; Gesslbauer, Bernd B; Jarc-Jovičić, Eva E; Hyötyläinen, Tuulia T; Ilc, Nejc N; Lakota, Katja K; Tomšič, Matija M; van de Loo, Fons A J FAJ; Bochkov, Valery V; Petan, Toni T; Jerala, Roman R; Manček-Keber, Mateja M
Publication Date: 2020-10-13

Variant appearance in text: TLR4: F440A
PubMed Link: 32973091
Variant Present in the following documents:
  • Main text
View BVdb publication page



Bordetella pertussis Lipid A Recognition by Toll-like Receptor 4 and MD-2 Is Dependent on Distinct Charged and Uncharged Interfaces.

The Journal Of Biological Chemistry
Maeshima, Nina N; Evans-Atkinson, Tara T; Hajjar, Adeline M AM; Fernandez, Rachel C RC
Publication Date: 2015-05-22

Variant appearance in text: TLR4: F440A
PubMed Link: 25837248
Variant Present in the following documents:
  • Main text
View BVdb publication page



Essential roles of hydrophobic residues in both MD-2 and toll-like receptor 4 in activation by endotoxin.

The Journal Of Biological Chemistry
Resman, Nusa N; Vasl, Jozica J; Oblak, Alja A; Pristovsek, Primoz P; Gioannini, Theresa L TL; Weiss, Jerrold P JP; Jerala, Roman R
Publication Date: 2009-05-29

Variant appearance in text: TLR4: F440A
PubMed Link: 19321453
Variant Present in the following documents:
  • Main text
View BVdb publication page