TLR4 c.2020_2021delinsGC ;(p.Y674A)

Variant ID: 9-120476426-TA-GC

NM_138554.4(TLR4):c.2020_2021delinsGC;(p.Y674A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


EGFR signaling augments TLR4 cell surface expression and function in macrophages via regulation of Rab5a activation.

Protein & Cell
Tang, Jing J; Zhou, Bowei B; Scott, Melanie J MJ; Chen, Linsong L; Lai, Dengming D; Fan, Erica K EK; Li, Yuehua Y; Wu, Qiang Q; Billiar, Timothy R TR; Wilson, Mark A MA; Wang, Ping P; Fan, Jie J
Publication Date: 2020-02

Variant appearance in text: TLR4: Y674A
PubMed Link: 31705388
Variant Present in the following documents:
  • 13238_2019_668_MOESM1_ESM.pdf
View BVdb publication page



Tyrosine 870 of TLR9 is critical for receptor maturation rather than phosphorylation-dependent ligand-induced signaling.

Plos One
Biswas, Chhanda C; Rao, Sheila S; Slade, Katharine K; Hyman, David D; Dersh, Devin D; Mantegazza, Adriana R AR; Zoltick, Philip W PW; Marks, Michael S MS; Argon, Yair Y; Behrens, Edward M EM
Publication Date: 2018

Variant appearance in text: TLR4: Y674A
PubMed Link: 30024926
Variant Present in the following documents:
  • Main text
  • pone.0200913.pdf
View BVdb publication page



Molecular mechanisms of regulation of Toll-like receptor signaling.

Journal Of Leukocyte Biology
Leifer, Cynthia A CA; Medvedev, Andrei E AE
Publication Date: 2016-11

Variant appearance in text: TLR4: Y674A
PubMed Link: 27343013
Variant Present in the following documents:
  • Main text
View BVdb publication page



Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling.

Cellular And Molecular Life Sciences : Cmls
Płóciennikowska, Agnieszka A; Hromada-Judycka, Aneta A; Borzęcka, Kinga K; Kwiatkowska, Katarzyna K
Publication Date: 2015-02

Variant appearance in text: TLR4: Y674A
PubMed Link: 25332099
Variant Present in the following documents:
  • Main text
  • 18_2014_Article_1762.pdf
View BVdb publication page



Tyrosine phosphorylation in Toll-like receptor signaling.

Cytokine & Growth Factor Reviews
Chattopadhyay, Saurabh S; Sen, Ganes C GC
Publication Date: 2014-10

Variant appearance in text: TLR4: Y674A
PubMed Link: 25022196
Variant Present in the following documents:
  • Main text
View BVdb publication page



Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance.

The Journal Of Biological Chemistry
Medvedev, Andrei E AE; Piao, Wenji W; Shoenfelt, Joanna J; Rhee, Sang Hoon SH; Chen, Haiyan H; Basu, Subhendu S; Wahl, Larry M LM; Fenton, Matthew J MJ; Vogel, Stefanie N SN
Publication Date: 2007-06-01

Variant appearance in text: TLR4: Y674A
PubMed Link: 17392283
Variant Present in the following documents:
  • Main text
View BVdb publication page