TLR4 c.2140C>G ;(p.P714A)

Variant ID: 9-120476546-C-G

NM_138554.4(TLR4):c.2140C>G;(p.P714A)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Src family kinase tyrosine phosphorylates Toll-like receptor 4 to dissociate MyD88 and Mal/Tirap, suppressing LPS-induced inflammatory responses.

Biochemical Pharmacology
Mitchell, Jonathon J; Kim, Su Jin SJ; Seelmann, Alexandra A; Veit, Brendan B; Shepard, Brooke B; Im, Eunok E; Rhee, Sang Hoon SH
Publication Date: 2018-01

Variant appearance in text: TLR4: P714A
PubMed Link: 29175418
Variant Present in the following documents:
  • Main text
View BVdb publication page



Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance.

The Journal Of Biological Chemistry
Medvedev, Andrei E AE; Piao, Wenji W; Shoenfelt, Joanna J; Rhee, Sang Hoon SH; Chen, Haiyan H; Basu, Subhendu S; Wahl, Larry M LM; Fenton, Matthew J MJ; Vogel, Stefanie N SN
Publication Date: 2007-06-01

Variant appearance in text: TLR4: P714A
PubMed Link: 17392283
Variant Present in the following documents:
  • Main text
View BVdb publication page