Publications:

The Architecture of the TIR Domain Signalosome in the Toll-like Receptor-4 Signaling Pathway.

Scientific Reports

Guven-Maiorov, Emine E; Keskin, Ozlem O; Gursoy, Attila A; VanWaes, Carter C; Chen, Zhong Z; Tsai, Chung-Jung CJ; Nussinov, Ruth R

Publication Date: 2015-08-21

Variant appearance in text: TLR4: C747S

PubMed Link: 26293885

Variant Present in the following documents:

• Main text
• srep13128.pdf

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Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model.

British Journal Of Pharmacology

Takashima, K K; Matsunaga, N N; Yoshimatsu, M M; Hazeki, K K; Kaisho, T T; Uekata, M M; Hazeki, O O; Akira, S S; Iizawa, Y Y; Ii, M M

Publication Date: 2009-08

Variant appearance in text: TLR4: C747S

PubMed Link: 19563534

Variant Present in the following documents:

• Main text

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A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins.

Plos One

Núñez Miguel, Ricardo R; Wong, Joyce J; Westoll, Julian F JF; Brooks, Heather J HJ; O'Neill, Luke A J LA; Gay, Nicholas J NJ; Bryant, Clare E CE; Monie, Tom P TP

Publication Date: 2007-08-29

Variant appearance in text: TLR4: C747S

PubMed Link: 17726518

Variant Present in the following documents:

• Main text
• pone.0000788.pdf

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