Publications:

Integrated molecular characterization reveals potential therapeutic strategies for pulmonary sarcomatoid carcinoma.

Nature Communications

Yang, Zhenlin Z; Xu, Jiachen J; Li, Lin L; Li, Renda R; Wang, Yalong Y; Tian, Yanhua Y; Guo, Wei W; Wang, Zhijie Z; Tan, Fengwei F; Ying, Jianming J; Jiao, Yuchen Y; Gao, Shugeng S; Wang, Jie J; Gao, Yibo Y; He, Jie J

Publication Date: 2020-09-28

Variant appearance in text: TLR4: 2240G>C; Cys747Ser

PubMed Link: 32985499

Variant Present in the following documents:

• 41467_2020_18702_MOESM5_ESM.xlsx, sheet 1

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The Architecture of the TIR Domain Signalosome in the Toll-like Receptor-4 Signaling Pathway.

Scientific Reports

Guven-Maiorov, Emine E; Keskin, Ozlem O; Gursoy, Attila A; VanWaes, Carter C; Chen, Zhong Z; Tsai, Chung-Jung CJ; Nussinov, Ruth R

Publication Date: 2015-08-21

Variant appearance in text: TLR4: C747S

PubMed Link: 26293885

Variant Present in the following documents:

• Main text
• srep13128.pdf

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Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model.

British Journal Of Pharmacology

Takashima, K K; Matsunaga, N N; Yoshimatsu, M M; Hazeki, K K; Kaisho, T T; Uekata, M M; Hazeki, O O; Akira, S S; Iizawa, Y Y; Ii, M M

Publication Date: 2009-08

Variant appearance in text: TLR4: C747S

PubMed Link: 19563534

Variant Present in the following documents:

• Main text

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A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins.

Plos One

Núñez Miguel, Ricardo R; Wong, Joyce J; Westoll, Julian F JF; Brooks, Heather J HJ; O'Neill, Luke A J LA; Gay, Nicholas J NJ; Bryant, Clare E CE; Monie, Tom P TP

Publication Date: 2007-08-29

Variant appearance in text: TLR4: C747S

PubMed Link: 17726518

Variant Present in the following documents:

• Main text
• pone.0000788.pdf

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