TLR4 c.2269_2270delinsGC ;(p.W757A)

Variant ID: 9-120476675-TG-GC

NM_138554.4(TLR4):c.2269_2270delinsGC;(p.W757A)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Identification of interaction sites for dimerization and adapter recruitment in Toll/interleukin-1 receptor (TIR) domain of Toll-like receptor 4.

The Journal Of Biological Chemistry
Bovijn, Celia C; Ulrichts, Peter P; De Smet, Anne-Sophie AS; Catteeuw, Dominiek D; Beyaert, Rudi R; Tavernier, Jan J; Peelman, Frank F
Publication Date: 2012-02-03

Variant appearance in text: TLR4: W757A
PubMed Link: 22139835
Variant Present in the following documents:
  • Main text
View BVdb publication page



A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins.

Plos One
Núñez Miguel, Ricardo R; Wong, Joyce J; Westoll, Julian F JF; Brooks, Heather J HJ; O'Neill, Luke A J LA; Gay, Nicholas J NJ; Bryant, Clare E CE; Monie, Tom P TP
Publication Date: 2007-08-29

Variant appearance in text: TLR4: Trp757Ala
PubMed Link: 17726518
Variant Present in the following documents:
  • Main text
  • pone.0000788.pdf
View BVdb publication page