TLR4 c.*2010G>C

Variant ID: 9-120478936-G-C

NM_138554.4(TLR4):c.*2010G>C

This variant was identified in 58 publications

View GRCh38 version.




Publications:


Association of Toll-like Receptors 1, 2, 4, 6, 8, 9 and 10 Genes Polymorphisms and Susceptibility to Pulmonary Tuberculosis in Sudanese Patients.

Immunotargets And Therapy
Mhmoud, Najwa A NA
Publication Date: 2023

Variant appearance in text: rs7873784
PubMed Link: 37051380
Variant Present in the following documents:
  • Main text
  • itt-12-47.pdf
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Polymorphisms in Genes Involved in Inflammation and Periodontitis: A Narrative Review.

Biomolecules
Brodzikowska, Aniela A; Górski, Bartłomiej B
Publication Date: 2022-04-07

Variant appearance in text: rs7873784
PubMed Link: 35454140
Variant Present in the following documents:
  • Main text
  • biomolecules-12-00552.pdf
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A Meta-Analysis for Association of XRCC3 rs861539, MTHFR rs1801133, IL-6 rs1800795, IL-12B rs3212227, TNF-α rs1800629, and TLR9 rs352140 Polymorphisms with Susceptibility to Cervical Carcinoma.

Asian Pacific Journal Of Cancer Prevention : Apjcp
Parsaeian, Seyedeh Fatemeh SF; Asadian, Fatemeh F; Karimi-Zarchi, Mojgan M; Setayesh, Sepideh S; Javaheri, Atiyeh A; Tabatabaie, Razieh Sadat RS; Dastgheib, Seyed Alireza SA; Golestanpour, Hossein H; Neamatzadeh, Hossein H
Publication Date: 2021-11-01

Variant appearance in text: rs7873784
PubMed Link: 34837895
Variant Present in the following documents:
  • Main text
  • APJCP-22-3419.pdf
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Disease-associated genetic variants in the regulatory regions of human genes: mechanisms of action on transcription and genomic resources for dissecting these mechanisms.

Vavilovskii Zhurnal Genetiki I Selektsii
Ignatieva, E V EV; Matrosova, E A EA
Publication Date: 2021-02

Variant appearance in text: rs7873784
PubMed Link: 34541447
Variant Present in the following documents:
  • Main text
  • VJGB-25-21003.pdf
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Association Between NR4A2 Gene Polymorphism and Depressive Symptoms and Antidepressant Effect.

Neuropsychiatric Disease And Treatment
Song, Xiaotong X; Sun, Ning N; Zhang, Aixia A; Lei, Lei L; Li, Xinrong X; Liu, Zhifen Z; Wang, Yanfang Y; Yang, Chunxia C; Zhang, Kerang K
Publication Date: 2021

Variant appearance in text: rs7873784
PubMed Link: 34408421
Variant Present in the following documents:
  • Main text
  • ndt-17-2613.pdf
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Regulatory SNPs: Altered Transcription Factor Binding Sites Implicated in Complex Traits and Diseases.

International Journal Of Molecular Sciences
Degtyareva, Arina O AO; Antontseva, Elena V EV; Merkulova, Tatiana I TI
Publication Date: 2021-06-16

Variant appearance in text: rs7873784
PubMed Link: 34208629
Variant Present in the following documents:
  • ijms-22-06454.pdf
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Correlation between TLR4 gene polymorphism and acute respiratory distress syndrome after esophageal cancer surgery.

American Journal Of Translational Research
Wang, Tongxin T; Wang, Lijun L; Zhu, Xiaojie X; Liu, Gengxi G
Publication Date: 2021

Variant appearance in text: rs7873784
PubMed Link: 34017507
Variant Present in the following documents:
  • Main text
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No association of genetic variants in TLR4, TNF-α, IL10, IFN-γ, and IL37 in cytomegalovirus-positive renal allograft recipients with active CMV infection-Subanalysis of the prospective randomised VIPP study.

Plos One
Mazzola, Pascale P; Schaeffeler, Elke E; Witzke, Oliver O; Nitschke, Martin M; Kliem, Volker V; Zortel, Max M; Wagner, Eva-Maria EM; Schwab, Matthias M; Hauser, Ingeborg A IA
Publication Date: 2021

Variant appearance in text: rs7873784
PubMed Link: 33861738
Variant Present in the following documents:
  • Main text
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Germline Genetic Variants of Viral Entry and Innate Immunity May Influence Susceptibility to SARS-CoV-2 Infection: Toward a Polygenic Risk Score for Risk Stratification.

Frontiers In Immunology
Grolmusz, Vince Kornél VK; Bozsik, Anikó A; Papp, János J; Patócs, Attila A
Publication Date: 2021

Variant appearance in text: rs7873784
PubMed Link: 33763088
Variant Present in the following documents:
  • Main text
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Innate and Adaptive Gene Single Nucleotide Polymorphisms Associated With Susceptibility of Severe Inflammatory Complications in Acanthamoeba Keratitis.

Investigative Ophthalmology & Visual Science
Carnt, Nicole A NA; Pang, Ignatius I; Burdon, Kathryn P KP; Calder, Virginia V; Dart, John K JK; Subedi, Dinesh D; Hardcastle, Alison J AJ
Publication Date: 2021-03-01

Variant appearance in text: rs7873784
PubMed Link: 33755043
Variant Present in the following documents:
  • Main text
  • iovs-62-3-33.pdf
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TLR4 promoter rs1927914 variant contributes to the susceptibility of esophageal squamous cell carcinoma in the Chinese population.

Peerj
Li, Jiaying J; Wu, Hongjiao H; Gao, Hui H; Kou, Ruihuan R; Xie, Yuning Y; Zhang, Zhi Z; Zhang, Xuemei X
Publication Date: 2021

Variant appearance in text: rs7873784
PubMed Link: 33585082
Variant Present in the following documents:
  • Main text
  • peerj-09-10754.pdf
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Single Nucleotide Polymorphisms Associated With Gut Homeostasis Influence Risk and Age-at-Onset of Parkinson's Disease.

Frontiers In Aging Neuroscience
Gorecki, Anastazja M AM; Bakeberg, Megan C MC; Theunissen, Frances F; Kenna, Jade E JE; Hoes, Madison E ME; Pfaff, Abigail L AL; Akkari, P Anthony PA; Dunlop, Sarah A SA; Kõks, Sulev S; Mastaglia, Frank L FL; Anderton, Ryan S RS
Publication Date: 2020

Variant appearance in text: rs7873784
PubMed Link: 33328979
Variant Present in the following documents:
  • Main text
  • fnagi-12-603849.pdf
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Polymorphisms of TLR2, TLR4 and TOLLIP and tuberculosis in two independent studies.

Bioscience Reports
Wu, Shouquan S; Liu, Xiangmin X; Chen, Ling L; Wang, Yu Y; Zhang, Miaomiao M; Wang, Minggui M; He, Jian-Qing JQ
Publication Date: 2020-08-28

Variant appearance in text: rs7873784
PubMed Link: 32648572
Variant Present in the following documents:
  • Main text
  • bsr-40-bsr20193141.pdf
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TLR4 polymorphisms may increase susceptibility to periodontitis in Pg-positive individuals.

Peerj
Li, Wenjing W; Cao, Xiaojing X; He, Lu L; Meng, Huanxin H; Yang, Bingtao B; Liao, Yanting Y
Publication Date: 2019

Variant appearance in text: rs7873784
PubMed Link: 31772831
Variant Present in the following documents:
  • Main text
  • peerj-07-7828.pdf
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Functional variations of the TLR4 gene in association with chronic obstructive pulmonary disease and pulmonary tuberculosis.

Bmc Pulmonary Medicine
Li, Zhongqi Z; Mao, Xuhua X; Liu, Qiao Q; Song, Huan H; He, Biyu B; Shi, Peiyi P; Zhang, Qun Q; Li, Xiaona X; Wang, Jianming J
Publication Date: 2019-10-22

Variant appearance in text: rs7873784
PubMed Link: 31640653
Variant Present in the following documents:
  • Main text
  • 12890_2019_Article_939.pdf
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Pathogenesis of Important Virulence Factors of Porphyromonas gingivalis via Toll-Like Receptors.

Frontiers In Cellular And Infection Microbiology
Jia, Lu L; Han, Nannan N; Du, Juan J; Guo, Lijia L; Luo, Zhenhua Z; Liu, Yi Y
Publication Date: 2019

Variant appearance in text: rs7873784
PubMed Link: 31380305
Variant Present in the following documents:
  • Main text
  • fcimb-09-00262.pdf
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Association of TLR4 and TLR9 polymorphisms and haplotypes with cervical cancer susceptibility.

Scientific Reports
Pandey, Nilesh O NO; Chauhan, Alex V AV; Raithatha, Nitin S NS; Patel, Purvi K PK; Khandelwal, Ronak R; Desai, Ajesh N AN; Choxi, Yesha Y; Kapadia, Rutul S RS; Jain, Neeraj D ND
Publication Date: 2019-07-05

Variant appearance in text: rs7873784
PubMed Link: 31278284
Variant Present in the following documents:
  • Main text
  • 41598_2019_Article_46077.pdf
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The predictive role of toll-like receptor-4 genetic polymorphisms in susceptibility to and prognosis of prostatic hyperplasia.

Iranian Journal Of Basic Medical Sciences
Qiu, Yunhua Y; Zheng, Jinzhou J; Yang, Jianfeng J; Li, Feng F; Zhou, Xiqiu X; Song, Xiaoyun X
Publication Date: 2019-01

Variant appearance in text: rs7873784
PubMed Link: 30944713
Variant Present in the following documents:
  • Main text
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The Role of Polymorphisms in Genes of PI3K/Akt Signaling Pathway on Prostate.

Journal Of Cancer
Xu, Wei W; Ni, Zhihao Z; Zhang, Meng M; Chen, Jinbo J; Zhang, Li L; Wu, Song S; Liang, Chaozhao C
Publication Date: 2019

Variant appearance in text: rs7873784
PubMed Link: 30854108
Variant Present in the following documents:
  • Main text
View BVdb publication page



Oral Mucosal Epithelial Cells.

Frontiers In Immunology
Groeger, Sabine S; Meyle, Joerg J
Publication Date: 2019

Variant appearance in text: rs7873784
PubMed Link: 30837987
Variant Present in the following documents:
  • Main text
  • fimmu-10-00208.pdf
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Influence of Genetic Polymorphism Towards Pulmonary Tuberculosis Susceptibility.

Frontiers In Medicine
Harishankar, Murugesan M; Selvaraj, Paramasivam P; Bethunaickan, Ramalingam R
Publication Date: 2018

Variant appearance in text: rs7873784
PubMed Link: 30167433
Variant Present in the following documents:
  • Main text
  • fmed-05-00213.pdf
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A preliminary assessment of Toll-like receptor and β-defensin gene polymorphisms in Papua New Guinea - what does it mean for HIV/AIDS?

Papua And New Guinea Medical Journal
Willie, Barne B; Gare, Janet J; King, Christopher L CL; Zimmerman, Peter A PA; Mehlotra, Rajeev K RK
Publication Date: 2017

Variant appearance in text: rs7873784
PubMed Link: 30147152
Variant Present in the following documents:
  • Main text
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Genetic variations in the TLR3 locus are associated with eosinophilic esophagitis.

United European Gastroenterology Journal
Ávila-Castellano, Robledo R; García-Lozano, José-Raúl JR; Cimbollek, Stefan S; Lucendo, Alfredo J AJ; Bozada, Juan-Manuel JM; Quiralte, Joaquín J
Publication Date: 2018-04

Variant appearance in text: rs7873784
PubMed Link: 29774148
Variant Present in the following documents:
  • Main text
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The association analysis of TLR2 and TLR4 gene with tuberculosis in the Tibetan Chinese population.

Oncotarget
Xue, Xin X; Qiu, Yi Y; Jiang, Dong D; Jin, Tianbo T; Yan, Mengdan M; Zhu, Xikang X; Chu, Yonglie Y
Publication Date: 2017-12-22

Variant appearance in text: rs7873784
PubMed Link: 29348888
Variant Present in the following documents:
  • Main text
  • oncotarget-08-113082.pdf
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Expression level of human TLR4 rather than sequence is the key determinant of LPS responsiveness.

Plos One
Hajjar, Adeline M AM; Ernst, Robert K RK; Yi, Jaehun J; Yam, Cathy S CS; Miller, Samuel I SI
Publication Date: 2017

Variant appearance in text: rs7873784
PubMed Link: 29020088
Variant Present in the following documents:
  • Main text
  • pone.0186308.pdf
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Periodontal Initial Radiological Findings of Genetically Predisposed Finnish Adolescents.

Journal Of Clinical And Diagnostic Research : Jcdr
Heikkinen, Anna Maria AM; Pakbaznejad Esmaeili, Elmira E; Kovanen, Leena L; Ruokonen, Hellevi H; Kettunen, Kaisa K; Haukka, Jari J; Tervahartiala, Taina T; Sorsa, Timo T
Publication Date: 2017-07

Variant appearance in text: rs7873784
PubMed Link: 28893037
Variant Present in the following documents:
  • Main text
View BVdb publication page



Immune-related gene polymorphisms in pulmonary diseases.

Toxicology
Singh, Dhirendra P DP; Bagam, Prathyusha P; Sahoo, Malaya K MK; Batra, Sanjay S
Publication Date: 2017-05-15

Variant appearance in text: rs7873784
PubMed Link: 28366820
Variant Present in the following documents:
  • Main text
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TLR4 rs41426344 increases susceptibility of rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) in a central south Chinese Han population.

Pediatric Rheumatology Online Journal
Wang, Yan Y; Chen, Lianghui L; Li, Fang F; Bao, Meihua M; Zeng, Jie J; Xiang, Ju J; Luo, Huaiqing H; Li, Jianming J; Tang, Liang L
Publication Date: 2017-02-21

Variant appearance in text: rs7873784
PubMed Link: 28222760
Variant Present in the following documents:
  • Main text
View BVdb publication page



Promoter Polymorphism of Toll-Like Receptor 4 is Associated with a Decreased Risk of Coronary Artery Disease: A Case-Control Study in the Chinese Han Population.

Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research
Sun, Dandan D; Sun, Liping L; Xu, Qian Q; Wang, Honghu H; Yang, Jun J; Yuan, Yuan Y
Publication Date: 2017-01-16

Variant appearance in text: rs7873784
PubMed Link: 28092654
Variant Present in the following documents:
  • Main text
  • medscimonit-23-276.pdf
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The role of genetics and antibodies in sepsis.

Annals Of Translational Medicine
Giamarellos-Bourboulis, Evangelos J EJ; Opal, Steven M SM
Publication Date: 2016-09

Variant appearance in text: rs7873784
PubMed Link: 27713886
Variant Present in the following documents:
  • Main text
View BVdb publication page



TLR4 polymorphism and periodontitis susceptibility: A meta-analysis.

Medicine
Jin, Su-Han SH; Guan, Xiao-Yan XY; Liang, Wen-Hong WH; Bai, Guo-Hui GH; Liu, Jian-Guo JG
Publication Date: 2016-09

Variant appearance in text: rs7873784
PubMed Link: 27603404
Variant Present in the following documents:
  • Main text
  • medi-95-e4845.pdf
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Genetic polymorphisms of IL-17A, IL-17F, TLR4 and miR-146a in association with the risk of pulmonary tuberculosis.

Scientific Reports
Wang, Min M; Xu, Guisheng G; Lü, Lingshuang L; Xu, Kun K; Chen, Yongzhong Y; Pan, Hongqiu H; Burstrom, Bo B; Burstrom, Kristina K; Wang, Jianming J
Publication Date: 2016-06-24

Variant appearance in text: rs7873784
PubMed Link: 27339100
Variant Present in the following documents:
  • Main text
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Association between Toll-Like Receptor 4 and Occurrence of Type 2 Diabetes Mellitus Susceptible to Pulmonary Tuberculosis in Northeast China.

Stem Cells International
Li, Yuze Y; Li, Dianzhong D; Zhang, Jinfeng J; Liu, Shurui S; Chen, Haijun H; Wu, Kun K
Publication Date: 2016

Variant appearance in text: rs7873784
PubMed Link: 27123010
Variant Present in the following documents:
  • Main text
  • SCI2016-8160318.pdf
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Molecular Genetic of Atopic dermatitis: An Update.

International Journal Of Health Sciences
Al-Shobaili, Hani A HA; Ahmed, Ahmed A AA; Alnomair, Naief N; Alobead, Zeiad Abdulaziz ZA; Rasheed, Zafar Z
Publication Date: 2016-01

Variant appearance in text: rs7873784
PubMed Link: 27004062
Variant Present in the following documents:
  • Main text
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Association of Toll-like receptor 4 (TLR4) with chronic plaque type psoriasis and psoriatic arthritis.

Archives Of Dermatological Research
Smith, Rh Ll RL; Hébert, H L HL; Massey, J J; Bowes, J J; Marzo-Ortega, H H; Ho, P P; McHugh, N J NJ; Worthington, J J; Barton, A A; Griffiths, C E M CE; Warren, R B RB
Publication Date: 2016-04

Variant appearance in text: rs7873784
PubMed Link: 26830904
Variant Present in the following documents:
  • Main text
  • 403_2016_Article_1620.pdf
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Genetic Variants in the Insulin-like Growth Factor Pathway and Colorectal Cancer Risk in the Netherlands Cohort Study.

Scientific Reports
Simons, Colinda C J M CC; Schouten, Leo J LJ; Godschalk, Roger W L RW; van Engeland, Manon M; van den Brandt, Piet A PA; van Schooten, Frederik J FJ; Weijenberg, Matty P MP
Publication Date: 2015-09-18

Variant appearance in text: rs7873784
PubMed Link: 26381944
Variant Present in the following documents:
View BVdb publication page



Toll-like receptor 4 gene polymorphism is associated with chronic periodontitis.

International Journal Of Clinical And Experimental Medicine
Ding, Yuan-Sheng YS; Zhao, Yue Y; Xiao, Yuan-Yuan YY; Zhao, Gang G
Publication Date: 2015

Variant appearance in text: rs7873784
PubMed Link: 26131223
Variant Present in the following documents:
  • Main text
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Screening toll-like receptor markers to predict latent tuberculosis infection and subsequent tuberculosis disease in a Chinese population.

Bmc Medical Genetics
Wu, Linlin L; Hu, Yi Y; Li, Dange D; Jiang, Weili W; Xu, Biao B
Publication Date: 2015-04-01

Variant appearance in text: rs7873784
PubMed Link: 25928077
Variant Present in the following documents:
  • Main text
View BVdb publication page



The association of polymorphisms of TLR4 and CD14 genes with susceptibility to sepsis in a Chinese population.

Bmc Medical Genetics
Wang, Haiyan H; Wei, Yesheng Y; Zeng, Yi Y; Qin, Yueqiu Y; Xiong, Bin B; Qin, Gang G; Li, Jun J; Hu, Donghai D; Qiu, Xiaowen X; Sooranna, Suren R SR; Pinhu, Liao L
Publication Date: 2014-11-14

Variant appearance in text: rs7873784
PubMed Link: 25394369
Variant Present in the following documents:
  • Main text
View BVdb publication page



Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis.

Plos One
Weng, Pei-Hsuan PH; Huang, Yi-Ling YL; Page, John H JH; Chen, Jen-Hau JH; Xu, Jianfeng J; Koutros, Stella S; Berndt, Sonja S; Chanock, Stephen S; Yeager, Meredith M; Witte, John S JS; Eeles, Rosalind A RA; Easton, Douglas F DF; Neal, David E DE; Donovan, Jenny J; Hamdy, Freddie C FC; Muir, Kenneth R KR; Giles, Graham G; Severi, Gianluca G; Smith, Jeffrey R JR; Balistreri, Carmela R CR; Shui, Irene M IM; Chen, Yen-Ching YC
Publication Date: 2014

Variant appearance in text: rs7873784
PubMed Link: 25360682
Variant Present in the following documents:
  • Main text
  • pone.0110569.pdf
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Association of Toll-like receptor polymorphisms with HIV status in North Americans.

Genes And Immunity
Willie, B B; Hall, N B NB; Stein, C M CM; Jurevic, R J RJ; Weinberg, A A; Mehlotra, R K RK; Zimmerman, P A PA
Publication Date: 2014-12

Variant appearance in text: rs7873784
PubMed Link: 25253287
Variant Present in the following documents:
  • Main text
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Association of variants in genes related to the immune response and obesity with BPH in CLUE II.

Prostate Cancer And Prostatic Diseases
Lopez, D S DS; Peskoe, S B SB; Tsilidis, K K KK; Hoffman-Bolton, J J; Helzlsouer, K J KJ; Isaacs, W B WB; Smith, M W MW; Platz, E A EA
Publication Date: 2014-12

Variant appearance in text: rs7873784
PubMed Link: 25224558
Variant Present in the following documents:
  • Main text
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Inflammatory genetic markers of prostate cancer risk.

Cancers
Tindall, Elizabeth A EA; Hayes, Vanessa M VM; Petersen, Desiree C DC
Publication Date: 2010-06-08

Variant appearance in text: rs7873784
PubMed Link: 24281113
Variant Present in the following documents:
  • Main text
  • cancers-02-01198.pdf
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Sequence variants of toll like receptor 4 and late-onset Alzheimer's disease.

Plos One
Chen, Yen-Ching YC; Yip, Ping-Keung PK; Huang, Yi-Ling YL; Sun, Yu Y; Wen, Li-Li LL; Chu, Yi-Min YM; Chen, Ta-Fu TF
Publication Date: 2012

Variant appearance in text: rs7873784
PubMed Link: 23272070
Variant Present in the following documents:
  • Main text
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Genetic variation in TLR genes in Ugandan and South African populations and comparison with HapMap data.

Plos One
Baker, Allison R AR; Qiu, Feiyou F; Randhawa, April Kaur AK; Horne, David J DJ; Adams, Mark D MD; Shey, Muki M; Barnholtz-Sloan, Jill J; Mayanja-Kizza, Harriet H; Kaplan, Gilla G; Hanekom, Willem A WA; Boom, W Henry WH; Hawn, Thomas R TR; Stein, Catherine M CM; ,
Publication Date: 2012

Variant appearance in text: rs7873784
PubMed Link: 23112821
Variant Present in the following documents:
  • Main text
  • pone.0047597.pdf
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Donor polymorphisms of toll-like receptor 4 associated with graft failure in liver transplant recipients.

Liver Transplantation : Official Publication Of The American Association For The Study Of Liver Diseases And The International Liver Transplantation Society
Oetting, William S WS; Guan, Weihua W; Schladt, David P DP; Leduc, Robert E RE; Jacobson, Pamala A PA; Matas, Arthur J AJ; Chinnakotla, Srinath S; Schröppel, Bernd B; Murphy, Barbara T BT; Israni, Ajay K AK
Publication Date: 2012-12

Variant appearance in text: rs7873784
PubMed Link: 22987288
Variant Present in the following documents:
  • Main text
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Inherited variation in pattern recognition receptors and cancer: dangerous liaisons?

Cancer Management And Research
Kutikhin, Anton G AG; Yuzhalin, Arseniy E AE
Publication Date: 2012

Variant appearance in text: rs7873784
PubMed Link: 22427729
Variant Present in the following documents:
  • cmar-4-031.pdf
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