Activating NOTCH1 Mutations Define a Distinct Subgroup of Patients With Adenoid Cystic Carcinoma Who Have Poor Prognosis, Propensity to Bone and Liver Metastasis, and Potential Responsiveness to Notch1 Inhibitors.
Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology
Ferrarotto, Renata R; Mitani, Yoshitsugu Y; Diao, Lixia L; Guijarro, Irene I; Wang, Jing J; Zweidler-McKay, Patrick P; Bell, Diana D; William, William N WN; Glisson, Bonnie S BS; Wick, Michael J MJ; Kapoun, Ann M AM; Patnaik, Amita A; Eckhardt, Gail G; Munster, Pamela P; Faoro, Leonardo L; Dupont, Jakob J; Lee, J Jack JJ; Futreal, Andrew A; El-Naggar, Adel K AK; Heymach, John V JV
Whole exome sequencing of adenoid cystic carcinoma.
The Journal Of Clinical Investigation
Stephens, Philip J PJ; Davies, Helen R HR; Mitani, Yoshitsugu Y; Van Loo, Peter P; Shlien, Adam A; Tarpey, Patrick S PS; Papaemmanuil, Elli E; Cheverton, Angela A; Bignell, Graham R GR; Butler, Adam P AP; Gamble, John J; Gamble, Stephen S; Hardy, Claire C; Hinton, Jonathan J; Jia, Mingming M; Jayakumar, Alagu A; Jones, David D; Latimer, Calli C; McLaren, Stuart S; McBride, David J DJ; Menzies, Andrew A; Mudie, Laura L; Maddison, Mark M; Raine, Keiran K; Nik-Zainal, Serena S; O'Meara, Sarah S; Teague, Jon W JW; Varela, Ignacio I; Wedge, David C DC; Whitmore, Ian I; Lippman, Scott M SM; McDermott, Ultan U; Stratton, Michael R MR; Campbell, Peter J PJ; El-Naggar, Adel K AK; Futreal, P Andrew PA