NOTCH1 c.944C>T ;(p.T315I)

Variant ID: 9-139413198-G-A

NM_017617.3(NOTCH1):c.944C>T;(p.T315I)

This variant was identified in 21 publications

View GRCh38 version.




Publications:


A generalizable machine learning framework for classifying DNA repair defects using ctDNA exomes.

Npj Precision Oncology
Ritch, Elie J EJ; Herberts, Cameron C; Warner, Evan W EW; Ng, Sarah W S SWS; Kwan, Edmond M EM; Bacon, Jack V W JVW; Bernales, Cecily Q CQ; Schönlau, Elena E; Fonseca, Nicolette M NM; Giri, Veda N VN; Maurice-Dror, Corinne C; Vandekerkhove, Gillian G; Jones, Steven J M SJM; Chi, Kim N KN; Wyatt, Alexander W AW
Publication Date: 2023-03-13

Variant appearance in text: NOTCH1: T315I
PubMed Link: 36914848
Variant Present in the following documents:
  • 41698_2023_366_MOESM2_ESM.xlsx, sheet 4
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The association of complex genetic background with the prognosis of acute leukemia with ambiguous lineage.

Scientific Reports
Huang, Jin J; Zhou, Jing J; Xiao, Min M; Mao, Xia X; Zhu, Li L; Liu, Songya S; Li, Qinlu Q; Wang, Jin J; Zhou, Jianfeng J; Cai, Haodong H; Wang, Gaoxiang G
Publication Date: 2021-12-21

Variant appearance in text: NOTCH1: T315I
PubMed Link: 34934076
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_3709.pdf
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The association of complex genetic background with the prognosis of acute leukemia with ambiguous lineage.

Scientific Reports
Huang, Jin J; Zhou, Jing J; Xiao, Min M; Mao, Xia X; Zhu, Li L; Liu, Songya S; Li, Qinlu Q; Wang, Jin J; Zhou, Jianfeng J; Cai, Haodong H; Wang, Gaoxiang G
Publication Date: 2021-12-21

Variant appearance in text: NOTCH1: T315I
PubMed Link: 34934076
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_3709.pdf
View BVdb publication page



Pharmacological Modulation of Ubiquitin-Proteasome Pathways in Oncogenic Signaling.

International Journal Of Molecular Sciences
Sharma, Anmol A; Khan, Heena H; Singh, Thakur Gurjeet TG; Grewal, Amarjot Kaur AK; Najda, Agnieszka A; Kawecka-Radomska, Małgorzata M; Kamel, Mohamed M; Altyar, Ahmed E AE; Abdel-Daim, Mohamed M MM
Publication Date: 2021-11-04

Variant appearance in text: NOTCH1: T315I
PubMed Link: 34769401
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacological Modulation of Ubiquitin-Proteasome Pathways in Oncogenic Signaling.

International Journal Of Molecular Sciences
Sharma, Anmol A; Khan, Heena H; Singh, Thakur Gurjeet TG; Grewal, Amarjot Kaur AK; Najda, Agnieszka A; Kawecka-Radomska, Małgorzata M; Kamel, Mohamed M; Altyar, Ahmed E AE; Del-Daim, Mohamed M MM
Publication Date: 2021-11-04

Variant appearance in text: NOTCH1: T315I
PubMed Link: 34769401
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeted Therapy in Acute Lymphoblastic Leukaemia.

Journal Of Personalized Medicine
Salvaris, Ross R; Fedele, Pasquale Luke PL
Publication Date: 2021-07-25

Variant appearance in text: NOTCH1: T315I
PubMed Link: 34442359
Variant Present in the following documents:
  • Main text
View BVdb publication page



Gene Expression Profiling Predicts Sensitivity of Chronic Lymphocytic Leukemia Cells to Dasatinib.

Hemasphere
Blätte, Tamara J TJ; Machnicki, Marcin M MM; Glodkowska-Mrowka, Eliza E; Dolnik, Anna A; Karp, Marta M; Karczmarczyk, Agnieszka A; Giannopoulos, Krzysztof K; Bullinger, Lars L; Stoklosa, Tomasz T
Publication Date: 2021-01

Variant appearance in text: NOTCH1: T315I
PubMed Link: 33354656
Variant Present in the following documents:
  • hs9-5-e514.pdf
View BVdb publication page



A chemogenomic approach to identify personalized therapy for patients with relapse or refractory acute myeloid leukemia: results of a prospective feasibility study.

Blood Cancer Journal
Collignon, A A; Hospital, M A MA; Montersino, C C; Courtier, F F; Charbonnier, A A; Saillard, C C; D'Incan, E E; Mohty, B B; Guille, A A; Adelaïde, J J; Carbuccia, N N; Garnier, S S; Mozziconacci, M J MJ; Zemmour, C C; Pakradouni, J J; Restouin, A A; Castellano, R R; Chaffanet, M M; Birnbaum, D D; Collette, Y Y; Vey, N N
Publication Date: 2020-06-03

Variant appearance in text: NOTCH1: T315I
PubMed Link: 32488055
Variant Present in the following documents:
  • 41408_2020_330_MOESM1_ESM.pdf
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[Safety and efficacy of patients with refractory B-lymphoblastic leukemia treated with anti-CD19 CAR-T cell bridging to allogeneic hematopoietic stem cell transplantation].

Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi
Ai, H H; Yin, Q S QS; Wang, Q Q; Fu, Y W YW; Wei, X D XD; Song, Y P YP
Publication Date: 2020-03-14

Variant appearance in text: NOTCH1: T315I
PubMed Link: 32311895
Variant Present in the following documents:
  • Main text
  • cjh-41-03-239.pdf
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Role of protein kinase CK2 in antitumor drug resistance.

Journal Of Experimental & Clinical Cancer Research : Cr
Borgo, Christian C; Ruzzene, Maria M
Publication Date: 2019-07-05

Variant appearance in text: NOTCH1: T315I
PubMed Link: 31277672
Variant Present in the following documents:
  • Main text
  • 13046_2019_Article_1292.pdf
View BVdb publication page



The use of technical replication for detection of low-level somatic mutations in next-generation sequencing.

Nature Communications
Kim, Junho J; Kim, Dachan D; Lim, Jae Seok JS; Maeng, Ju Heon JH; Son, Hyeonju H; Kang, Hoon-Chul HC; Nam, Hojung H; Lee, Jeong Ho JH; Kim, Sangwoo S
Publication Date: 2019-03-05

Variant appearance in text: NOTCH1: T315I
PubMed Link: 30837471
Variant Present in the following documents:
  • 41467_2019_Article_9026.pdf
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A Convergence-Based Framework for Cancer Drug Resistance.

Cancer Cell
Konieczkowski, David J DJ; Johannessen, Cory M CM; Garraway, Levi A LA
Publication Date: 2018-05-14

Variant appearance in text: NOTCH1: T315I
PubMed Link: 29763622
Variant Present in the following documents:
  • Main text
View BVdb publication page



Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs.

Aging
McCubrey, James A JA; Lertpiriyapong, Kvin K; Steelman, Linda S LS; Abrams, Steve L SL; Yang, Li V LV; Murata, Ramiro M RM; Rosalen, Pedro L PL; Scalisi, Aurora A; Neri, Luca M LM; Cocco, Lucio L; Ratti, Stefano S; Martelli, Alberto M AM; Laidler, Piotr P; Dulińska-Litewka, Joanna J; Rakus, Dariusz D; Gizak, Agnieszka A; Lombardi, Paolo P; Nicoletti, Ferdinando F; Candido, Saverio S; Libra, Massimo M; Montalto, Giuseppe G; Cervello, Melchiorre M
Publication Date: 2017-06-12

Variant appearance in text: NOTCH1: T315I
PubMed Link: 28611316
Variant Present in the following documents:
  • Main text
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NF-κB in Hematological Malignancies.

Biomedicines
Imbert, Véronique V; Peyron, Jean-François JF
Publication Date: 2017-05-31

Variant appearance in text: NOTCH1: T315I
PubMed Link: 28561798
Variant Present in the following documents:
  • Main text
  • biomedicines-05-00027.pdf
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Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset.

Oncotarget
Padi, Sathish K R SKR; Luevano, Libia A LA; An, Ningfei N; Pandey, Ritu R; Singh, Neha N; Song, Jin H JH; Aster, Jon C JC; Yu, Xue-Zhong XZ; Mehrotra, Shikhar S; Kraft, Andrew S AS
Publication Date: 2017-05-02

Variant appearance in text: NOTCH1: T315I
PubMed Link: 28415816
Variant Present in the following documents:
  • oncotarget-08-30199.pdf
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Physicians Abstracts.

Bone Marrow Transplantation
Publication Date: 2016-03

Variant appearance in text: NOTCH1: T315I
PubMed Link: 26999536
Variant Present in the following documents:
  • 41409_2016_Article_BFbmt201646.pdf
View BVdb publication page



SRC family kinase (SFK) inhibition reduces rhabdomyosarcoma cell growth in vitro and in vivo and triggers p38 MAP kinase-mediated differentiation.

Oncotarget
Casini, Nadia N; Forte, Iris Maria IM; Mastrogiovanni, Gianmarco G; Pentimalli, Francesca F; Angelucci, Adriano A; Festuccia, Claudio C; Tomei, Valentina V; Ceccherini, Elisa E; Di Marzo, Domenico D; Schenone, Silvia S; Botta, Maurizio M; Giordano, Antonio A; Indovina, Paola P
Publication Date: 2015-05-20

Variant appearance in text: NOTCH1: T315I
PubMed Link: 25762618
Variant Present in the following documents:
  • oncotarget-06-12421.pdf
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Comparison of the cytotoxicity of cladribine and clofarabine when combined with fludarabine and busulfan in AML cells: Enhancement of cytotoxicity with epigenetic modulators.

Experimental Hematology
Valdez, Benigno C BC; Li, Yang Y; Murray, David D; Ji, Jie J; Liu, Yan Y; Popat, Uday U; Champlin, Richard E RE; Andersson, Borje S BS
Publication Date: 2015-06

Variant appearance in text: NOTCH1: Thr315Ile
PubMed Link: 25704054
Variant Present in the following documents:
  • Main text
View BVdb publication page



NF-κB in T-cell Acute Lymphoblastic Leukemia: Oncogenic Functions in Leukemic and in Microenvironmental Cells.

Cancers
Dos Santos, Nuno R NR; Ghezzo, Marinella N MN; da Silva, Ricardo C RC; Fernandes, Mónica T MT
Publication Date: 2010-11-05

Variant appearance in text: NOTCH1: T315I
PubMed Link: 24281204
Variant Present in the following documents:
  • cancers-02-01838.pdf
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Novel agents and biomarkers for acute lymphoid leukemia.

Journal Of Hematology & Oncology
Zhao, Yanmin Y; Huang, He H; Wei, Guoqing G
Publication Date: 2013-06-18

Variant appearance in text: NOTCH1: T315I
PubMed Link: 23773228
Variant Present in the following documents:
  • Main text
  • 1756-8722-6-40.pdf
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High chromosome number in hematological cancer cell lines is a negative predictor of response to the inhibition of Aurora B and C by GSK1070916.

Journal Of Translational Medicine
Moy, Christopher C; Oleykowski, Catherine A CA; Plant, Ramona R; Greshock, Joel J; Jing, Junping J; Bachman, Kurtis K; Hardwicke, Mary Ann MA; Wooster, Richard R; Degenhardt, Yan Y
Publication Date: 2011-07-15

Variant appearance in text: NOTCH1: T315I
PubMed Link: 21762492
Variant Present in the following documents:
  • 1479-5876-9-110.pdf
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Pediatric developmental therapies: interesting new drugs now in early-stage clinical trials.

Current Oncology Reports
Macy, Margaret E ME; Sawczyn, Kelly K KK; Garrington, Timothy P TP; Graham, Douglas K DK; Gore, Lia L
Publication Date: 2008-11

Variant appearance in text: NOTCH1: T315I
PubMed Link: 18928662
Variant Present in the following documents:
  • Main text
View BVdb publication page