Artificial Intelligence Predictive Models of Response to Cytotoxic Chemotherapy Alone or Combined to Targeted Therapy for Metastatic Colorectal Cancer Patients: A Systematic Review and Meta-Analysis.
Cancers
Russo, Valentina V; Lallo, Eleonora E; Munnia, Armelle A; Spedicato, Miriana M; Messerini, Luca L; D'Aurizio, Romina R; Ceroni, Elia Giuseppe EG; Brunelli, Giulia G; Galvano, Antonio A; Russo, Antonio A; Landini, Ida I; Nobili, Stefania S; Ceppi, Marcello M; Bruzzone, Marco M; Cianchi, Fabio F; Staderini, Fabio F; Roselli, Mario M; Riondino, Silvia S; Ferroni, Patrizia P; Guadagni, Fiorella F; Mini, Enrico E; Peluso, Marco M
Identification of 22 susceptibility loci associated with testicular germ cell tumors.
Nature Communications
Pluta, John J; Pyle, Louise C LC; Nead, Kevin T KT; Wilf, Rona R; Li, Mingyao M; Mitra, Nandita N; Weathers, Benita B; D'Andrea, Kurt K; Almstrup, Kristian K; Anson-Cartwright, Lynn L; Benitez, Javier J; Brown, Christopher D CD; Chanock, Stephen S; Chen, Chu C; Cortessis, Victoria K VK; Ferlin, Alberto A; Foresta, Carlo C; Gamulin, Marija M; Gietema, Jourik A JA; Grasso, Chiara C; Greene, Mark H MH; Grotmol, Tom T; Hamilton, Robert J RJ; Haugen, Trine B TB; Hauser, Russ R; Hildebrandt, Michelle A T MAT; Johnson, Matthew E ME; Karlsson, Robert R; Kiemeney, Lambertus A LA; Lessel, Davor D; Lothe, Ragnhild A RA; Loud, Jennifer T JT; Loveday, Chey C; Martin-Gimeno, Paloma P; Meijer, Coby C; Nsengimana, Jérémie J; Quinn, David I DI; Rafnar, Thorunn T; Ramdas, Shweta S; Richiardi, Lorenzo L; Skotheim, Rolf I RI; Stefansson, Kari K; Turnbull, Clare C; Vaughn, David J DJ; Wiklund, Fredrik F; Wu, Xifeng X; Yang, Daphne D; Zheng, Tongzhang T; Wells, Andrew D AD; Grant, Struan F A SFA; Rajpert-De Meyts, Ewa E; Schwartz, Stephen M SM; Bishop, D Timothy DT; McGlynn, Katherine A KA; Kanetsky, Peter A PA; Nathanson, Katherine L KL; ,
Random survival forests identify pathways with polymorphisms predictive of survival in KRAS mutant and KRAS wild-type metastatic colorectal cancer patients.
Scientific Reports
Naseem, Madiha M; Cao, Shu S; Yang, Dongyun D; Millstein, Joshua J; Puccini, Alberto A; Loupakis, Fotios F; Stintzing, Sebastian S; Cremolini, Chiara C; Tokunaga, Ryuma R; Battaglin, Francesca F; Soni, Shivani S; Berger, Martin D MD; Barzi, Afsaneh A; Zhang, Wu W; Falcone, Alfredo A; Heinemann, Volker V; Lenz, Heinz-Josef HJ
Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways.
Nature Communications
Duffy, David L DL; Zhu, Gu G; Li, Xin X; Sanna, Marianna M; Iles, Mark M MM; Jacobs, Leonie C LC; Evans, David M DM; Yazar, Seyhan S; Beesley, Jonathan J; Law, Matthew H MH; Kraft, Peter P; Visconti, Alessia A; Taylor, John C JC; Liu, Fan F; Wright, Margaret J MJ; Henders, Anjali K AK; Bowdler, Lisa L; Glass, Dan D; Ikram, M Arfan MA; Uitterlinden, André G AG; Madden, Pamela A PA; Heath, Andrew C AC; Nelson, Elliot C EC; Green, Adele C AC; Chanock, Stephen S; Barrett, Jennifer H JH; Brown, Matthew A MA; Hayward, Nicholas K NK; MacGregor, Stuart S; Sturm, Richard A RA; Hewitt, Alex W AW; , ; Kayser, Manfred M; Hunter, David J DJ; Newton Bishop, Julia A JA; Spector, Timothy D TD; Montgomery, Grant W GW; Mackey, David A DA; Smith, George Davey GD; Nijsten, Tamar E TE; Bishop, D Timothy DT; Bataille, Veronique V; Falchi, Mario M; Han, Jiali J; Martin, Nicholas G NG
Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor.
Nature Genetics
Wang, Zhaoming Z; McGlynn, Katherine A KA; Rajpert-De Meyts, Ewa E; Bishop, D Timothy DT; Chung, Charles C CC; Dalgaard, Marlene D MD; Greene, Mark H MH; Gupta, Ramneek R; Grotmol, Tom T; Haugen, Trine B TB; Karlsson, Robert R; Litchfield, Kevin K; Mitra, Nandita N; Nielsen, Kasper K; Pyle, Louise C LC; Schwartz, Stephen M SM; Thorsson, Vésteinn V; Vardhanabhuti, Saran S; Wiklund, Fredrik F; Turnbull, Clare C; Chanock, Stephen J SJ; Kanetsky, Peter A PA; Nathanson, Katherine L KL; ,
Variants in BAK1, SPRY4, and GAB2 are associated with pediatric germ cell tumors: A report from the children's oncology group.
Genes, Chromosomes & Cancer
Marcotte, Erin L EL; Pankratz, Nathan N; Amatruda, James F JF; Frazier, A Lindsay AL; Krailo, Mark M; Davies, Stella S; Starr, Jacqueline R JR; Lau, Ching C CC; Roesler, Michelle M; Langer, Erica E; Hallstrom, Caroline C; Hooten, Anthony J AJ; Poynter, Jenny N JN
Cross platform analysis of methylation, miRNA and stem cell gene expression data in germ cell tumors highlights characteristic differences by tumor histology.
Bmc Cancer
Poynter, Jenny N JN; Bestrashniy, Jessica R B M JR; Silverstein, Kevin A T KA; Hooten, Anthony J AJ; Lees, Christopher C; Ross, Julie A JA; Tolar, Jakub J
Pathway-based analysis of GWAs data identifies association of sex determination genes with susceptibility to testicular germ cell tumors.
Human Molecular Genetics
Koster, Roelof R; Mitra, Nandita N; D'Andrea, Kurt K; Vardhanabhuti, Saran S; Chung, Charles C CC; Wang, Zhaoming Z; Loren Erickson, R R; Vaughn, David J DJ; Litchfield, Kevin K; Rahman, Nazneen N; Greene, Mark H MH; McGlynn, Katherine A KA; Turnbull, Clare C; Chanock, Stephen J SJ; Nathanson, Katherine L KL; Kanetsky, Peter A PA
Variants in or near KITLG, BAK1, DMRT1, and TERT-CLPTM1L predispose to familial testicular germ cell tumour.
Journal Of Medical Genetics
Kratz, Christian P CP; Han, Summer S SS; Rosenberg, Philip S PS; Berndt, Sonja I SI; Burdett, Laurie L; Yeager, Meredith M; Korde, Larissa A LA; Mai, Phuong L PL; Pfeiffer, Ruth R; Greene, Mark H MH
A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility.
Human Molecular Genetics
Kanetsky, Peter A PA; Mitra, Nandita N; Vardhanabhuti, Saran S; Vaughn, David J DJ; Li, Mingyao M; Ciosek, Stephanie L SL; Letrero, Richard R; D'Andrea, Kurt K; Vaddi, Madhavi M; Doody, David R DR; Weaver, Joellen J; Chen, Chu C; Starr, Jacqueline R JR; Håkonarson, Håkon H; Rader, Daniel J DJ; Godwin, Andrew K AK; Reilly, Muredach P MP; Schwartz, Stephen M SM; Nathanson, Katherine L KL
Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.
Nature Genetics
Turnbull, Clare C; Rapley, Elizabeth A EA; Seal, Sheila S; Pernet, David D; Renwick, Anthony A; Hughes, Deborah D; Ricketts, Michelle M; Linger, Rachel R; Nsengimana, Jeremie J; Deloukas, Panagiotis P; Huddart, Robert A RA; Bishop, D Timothy DT; Easton, Douglas F DF; Stratton, Michael R MR; Rahman, Nazneen N; ,