MHC class II restricted neoantigen peptides predicted by clonal mutation analysis in lung adenocarcinoma patients: implications on prognostic immunological biomarker and vaccine design.
Noncovalent stabilization of the factor VIII A2 domain enhances efficacy in hemophilia A mouse vascular injury models.
Blood
Leong, Lilley L; Sim, Derek D; Patel, Chandra C; Tran, Katherine K; Liu, Perry P; Ho, Elena E; Thompson, Thomas T; Kretschmer, Peter J PJ; Wakabayashi, Hironao H; Fay, Philip J PJ; Murphy, John E JE
Role of hydrophobic mutations on the binding affinity and stability of blood coagulation factor VIIIa: a computational molecular dynamics and free-energy analysis.
Biochemical And Biophysical Research Communications
Enhanced factor VIIIa stability of A2 domain interface variants results from an increased apparent affinity for the A2 subunit. Results from an increased apparent affinity for the A2 subunit.
Thrombosis And Haemostasis
Monaghan, M M; Wakabayashi, H H; Griffiths, A A; Wintermute, J J; Fay, P J PJ