Publications:

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Integrated analysis of genomic and transcriptomic data for the discovery of splice-associated variants in cancer.

Nature Communications

Cotto, Kelsy C KC; Feng, Yang-Yang YY; Ramu, Avinash A; Richters, Megan M; Freshour, Sharon L SL; Skidmore, Zachary L ZL; Xia, Huiming H; McMichael, Joshua F JF; Kunisaki, Jason J; Campbell, Katie M KM; Chen, Timothy Hung-Po TH; Rozycki, Emily B EB; Adkins, Douglas D; Devarakonda, Siddhartha S; Sankararaman, Sumithra S; Lin, Yiing Y; Chapman, William C WC; Maher, Christopher A CA; Arora, Vivek V; Dunn, Gavin P GP; Uppaluri, Ravindra R; Govindan, Ramaswamy R; Griffith, Obi L OL; Griffith, Malachi M

Publication Date: 2023-03-22

Variant appearance in text: PTEN: 477G>T; Arg159Ser

PubMed Link: 36949070

Variant Present in the following documents:

• 41467_2023_37266_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: rs1057519724

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 6

View BVdb publication page

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Calibration of computational tools for missense variant pathogenicity classification and ClinGen recommendations for PP3/BP4 criteria.

American Journal Of Human Genetics

Pejaver, Vikas V; Byrne, Alicia B AB; Feng, Bing-Jian BJ; Pagel, Kymberleigh A KA; Mooney, Sean D SD; Karchin, Rachel R; O'Donnell-Luria, Anne A; Harrison, Steven M SM; Tavtigian, Sean V SV; Greenblatt, Marc S MS; Biesecker, Leslie G LG; Radivojac, Predrag P; Brenner, Steven E SE; ,

Publication Date: 2022-12-01

Variant appearance in text: PTEN: R159S; rs1057519724

PubMed Link: 36413997

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

View BVdb publication page

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: PTEN: R159S

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: PTEN: 477G>T; R159S

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

View BVdb publication page

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Integrating thousands of PTEN variant activity and abundance measurements reveals variant subgroups and new dominant negatives in cancers.

Genome Medicine

Matreyek, Kenneth A KA; Stephany, Jason J JJ; Ahler, Ethan E; Fowler, Douglas M DM

Publication Date: 2021-10-14

Variant appearance in text: PTEN: Arg159Ser

PubMed Link: 34649609

Variant Present in the following documents:

• Main text
• 13073_2021_Article_984.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: PTEN: R159S

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Assessment of Clinical Benefit of Integrative Genomic Profiling in Advanced Solid Tumors.

Jama Oncology

Cobain, Erin F EF; Wu, Yi-Mi YM; Vats, Pankaj P; Chugh, Rashmi R; Worden, Francis F; Smith, David C DC; Schuetze, Scott M SM; Zalupski, Mark M MM; Sahai, Vaibhav V; Alva, Ajjai A; Schott, Anne F AF; Caram, Megan E V MEV; Hayes, Daniel F DF; Stoffel, Elena M EM; Jacobs, Michelle F MF; Kumar-Sinha, Chandan C; Cao, Xuhong X; Wang, Rui R; Lucas, David D; Ning, Yu Y; Rabban, Erica E; Bell, Janice J; Camelo-Piragua, Sandra S; Udager, Aaron M AM; Cieslik, Marcin M; Lonigro, Robert J RJ; Kunju, Lakshmi P LP; Robinson, Dan R DR; Talpaz, Moshe M; Chinnaiyan, Arul M AM

Publication Date: 2021-04-01

Variant appearance in text: PTEN: R159S

PubMed Link: 33630025

Variant Present in the following documents:

• jamaoncol-e207987-s004.xlsx, sheet 2

View BVdb publication page

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The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study.

Frontiers In Immunology

Punta, Marco M; Jennings, Victoria A VA; Melcher, Alan A AA; Lise, Stefano S

Publication Date: 2020

Variant appearance in text: PTEN: R159S

PubMed Link: 33133066

Variant Present in the following documents:

• Table_6.xlsx, sheet 9
• Table_1.xlsx, sheet 4
• Table_1.xlsx, sheet 8
• Table_2.xlsx, sheet 7
• Table_2.xlsx, sheet 1
• Table_6.xlsx, sheet 4
• Table_2.xlsx, sheet 2

View BVdb publication page

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Molecular correlates and therapeutic targets in T cell-inflamed versus non-T cell-inflamed tumors across cancer types.

Genome Medicine

Bao, Riyue R; Stapor, Daniel D; Luke, Jason J JJ

Publication Date: 2020-10-27

Variant appearance in text: PTEN: R159S

PubMed Link: 33106165

Variant Present in the following documents:

• 13073_2020_787_MOESM1_ESM.xlsx, sheet 9

View BVdb publication page

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mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports

Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM

Publication Date: 2020-06-23

Variant appearance in text: PTEN: R159S

PubMed Link: 32579932

Variant Present in the following documents:

• mmc5.xlsx, sheet 3

View BVdb publication page

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Phase and context shape the function of composite oncogenic mutations.

Nature

Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS

Publication Date: 2020-06

Variant appearance in text: PTEN: R159S

PubMed Link: 32461694

Variant Present in the following documents:

• NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx, sheet 2

View BVdb publication page

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OncoOmics approaches to reveal essential genes in breast cancer: a panoramic view from pathogenesis to precision medicine.

Scientific Reports

López-Cortés, Andrés A; Paz-Y-Miño, César C; Guerrero, Santiago S; Cabrera-Andrade, Alejandro A; Barigye, Stephen J SJ; Munteanu, Cristian R CR; González-Díaz, Humberto H; Pazos, Alejandro A; Pérez-Castillo, Yunierkis Y; Tejera, Eduardo E

Publication Date: 2020-03-24

Variant appearance in text: PTEN: R159S

PubMed Link: 32210335

Variant Present in the following documents:

• 41598_2020_62279_MOESM2_ESM.xlsx, sheet 33

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: PTEN: R159S

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 2
• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology

Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M

Publication Date: 2020-01-07

Variant appearance in text: PTEN: 477G>T; R159S

PubMed Link: 31925297

Variant Present in the following documents:

• 42003_2019_736_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Refinement of evolutionary medicine predictions based on clinical evidence for the manifestations of Mendelian diseases.

Scientific Reports

Šimčíková, Daniela D; Heneberg, Petr P

Publication Date: 2019-12-09

Variant appearance in text: PTEN: R159S

PubMed Link: 31819097

Variant Present in the following documents:

• 41598_2019_54976_MOESM2_ESM.xlsx, sheet 8

View BVdb publication page

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Development and validation of a targeted gene sequencing panel for application to disparate cancers.

Scientific Reports

McCabe, Mark J MJ; Gauthier, Marie-Emilie A MA; Chan, Chia-Ling CL; Thompson, Tanya J TJ; De Sousa, Sunita M C SMC; Puttick, Clare C; Grady, John P JP; Gayevskiy, Velimir V; Tao, Jiang J; Ying, Kevin K; Cipponi, Arcadi A; Deng, Niantao N; Swarbrick, Alex A; Thomas, Melissa L ML; Lord, Reginald V RV; Johns, Amber L AL; Kohonen-Corish, Maija M; O'Toole, Sandra A SA; Clark, Jonathan J; Mueller, Simon A SA; Gupta, Ruta R; McCormack, Ann I AI; Dinger, Marcel E ME; Cowley, Mark J MJ; ,

Publication Date: 2019-11-19

Variant appearance in text: PTEN: 477G>T; R159S

PubMed Link: 31745186

Variant Present in the following documents:

• 41598_2019_52000_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Validation and Clinical Applications of a Comprehensive Next Generation Sequencing System for Molecular Characterization of Solid Cancer Tissues.

Frontiers In Molecular Biosciences

Dehghani, Mehdi M; Rosenblatt, Kevin P KP; Li, Lei L; Rakhade, Mrudula M; Amato, Robert J RJ

Publication Date: 2019

Variant appearance in text: PTEN: Arg159Ser

PubMed Link: 31681791

Variant Present in the following documents:

• Data_Sheet_5.pdf

View BVdb publication page

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Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health.

Pharmacological Reviews

Cheng, Feixiong F; Liang, Han H; Butte, Atul J AJ; Eng, Charis C; Nussinov, Ruth R

Publication Date: 2019-01

Variant appearance in text: PTEN: R159S

PubMed Link: 30545954

Variant Present in the following documents:

• Main text

View BVdb publication page

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Systematic Analysis of Splice-Site-Creating Mutations in Cancer.

Cell Reports

Jayasinghe, Reyka G RG; Cao, Song S; Gao, Qingsong Q; Wendl, Michael C MC; Vo, Nam Sy NS; Reynolds, Sheila M SM; Zhao, Yanyan Y; Climente-González, Héctor H; Chai, Shengjie S; Wang, Fang F; Varghese, Rajees R; Huang, Mo M; Liang, Wen-Wei WW; Wyczalkowski, Matthew A MA; Sengupta, Sohini S; Li, Zhi Z; Payne, Samuel H SH; Fenyö, David D; Miner, Jeffrey H JH; Walter, Matthew J MJ; , ; Vincent, Benjamin B; Eyras, Eduardo E; Chen, Ken K; Shmulevich, Ilya I; Chen, Feng F; Ding, Li L

Publication Date: 2018-04-03

Variant appearance in text: PTEN: 477G>T; Arg159Ser

PubMed Link: 29617666

Variant Present in the following documents:

• NIHMS958979-supplement-1.pdf
• NIHMS958979-supplement-6.pdf

View BVdb publication page

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Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations.

Genome Medicine

Tamborero, David D; Rubio-Perez, Carlota C; Deu-Pons, Jordi J; Schroeder, Michael P MP; Vivancos, Ana A; Rovira, Ana A; Tusquets, Ignasi I; Albanell, Joan J; Rodon, Jordi J; Tabernero, Josep J; de Torres, Carmen C; Dienstmann, Rodrigo R; Gonzalez-Perez, Abel A; Lopez-Bigas, Nuria N

Publication Date: 2018-03-28

Variant appearance in text: PTEN: R159S

PubMed Link: 29592813

Variant Present in the following documents:

• 13073_2018_531_MOESM2_ESM.pdf

View BVdb publication page

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Prevalence and detection of low-allele-fraction variants in clinical cancer samples.

Nature Communications

Shin, Hyun-Tae HT; Choi, Yoon-La YL; Yun, Jae Won JW; Kim, Nayoung K D NKD; Kim, Sook-Young SY; Jeon, Hyo Jeong HJ; Nam, Jae-Yong JY; Lee, Chung C; Ryu, Daeun D; Kim, Sang Cheol SC; Park, Kyunghee K; Lee, Eunjin E; Bae, Joon Seol JS; Son, Dae Soon DS; Joung, Je-Gun JG; Lee, Jeeyun J; Kim, Seung Tae ST; Ahn, Myung-Ju MJ; Lee, Se-Hoon SH; Ahn, Jin Seok JS; Lee, Woo Yong WY; Oh, Bo Young BY; Park, Yeon Hee YH; Lee, Jeong Eon JE; Lee, Kwang Hyuk KH; Kim, Hee Cheol HC; Kim, Kyoung-Mee KM; Im, Young-Hyuck YH; Park, Keunchil K; Park, Peter J PJ; Park, Woong-Yang WY

Publication Date: 2017-11-09

Variant appearance in text: PTEN: R159S

PubMed Link: 29123093

Variant Present in the following documents:

• 41467_2017_1470_MOESM11_ESM.xlsx, sheet 1

View BVdb publication page

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Prediction of a highly deleterious mutation E17K in AKT-1 gene: An in silico approach.

Biochemistry And Biophysics Reports

Khan, Imran I; Ansari, Irfan A IA

Publication Date: 2017-07

Variant appearance in text: PTEN: R159S

PubMed Link: 29114575

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Genomic markers of ovarian adenocarcinoma and its relevancy to the effectiveness of chemotherapy.

Oncology Letters

Englert-Golon, Monika M; Burchardt, Bartosz B; Budny, Bartlomiej B; Dębicki, Szymon S; Majchrzycka, Blanka B; Wrotkowska, Elzbieta E; Jasiński, Piotr P; Ziemnicka, Katarzyna K; Słopień, Radosław R; Ruchała, Marek M; Sajdak, Stefan S

Publication Date: 2017-09

Variant appearance in text: PTEN: 477G>T; R159S

PubMed Link: 28927094

Variant Present in the following documents:

• ol-14-03-3401.pdf

View BVdb publication page

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Comparing mutation calls in fixed tumour samples between the affymetrix OncoScan® array and PCR based next-generation sequencing.

Bmc Medical Genomics

Wood, Henry M HM; Foster, Joseph M JM; Taylor, Morag M; Tinkler-Hundal, Emma E; Togneri, Fiona S FS; Wojtowicz, Paula P; Oumie, Assa A; Spink, Karen G KG; Brew, Fiona F; Quirke, Philip P

Publication Date: 2017-03-18

Variant appearance in text: PTEN: 477G>T; R159S

PubMed Link: 28315634

Variant Present in the following documents:

• Main text
• 12920_2017_254_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Functional KRAS mutations and a potential role for PI3K/AKT activation in Wilms tumors.

Molecular Oncology

Polosukhina, Dina D; Love, Harold D HD; Correa, Hernan H; Su, Zengliu Z; Dahlman, Kimberly B KB; Pao, William W; Moses, Harold L HL; Arteaga, Carlos L CL; Lovvorn, Harold N HN; Zent, Roy R; Clark, Peter E PE

Publication Date: 2017-04

Variant appearance in text: PTEN: 477G>T; R159S

PubMed Link: 28188683

Variant Present in the following documents:

View BVdb publication page

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A Landscape of Pharmacogenomic Interactions in Cancer.

Cell

Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ

Publication Date: 2016-07-28

Variant appearance in text: PTEN: 477G>T; R159S

PubMed Link: 27397505

Variant Present in the following documents:

• mmc3.xlsx, sheet 3
• mmc3.xlsx, sheet 2

View BVdb publication page

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Genetic heterogeneity of RPMI-8402, a T-acute lymphoblastic leukemia cell line.

Oncology Letters

Stoczynska-Fidelus, Ewelina E; Piaskowski, Sylwester S; Pawlowska, Roza R; Szybka, Malgorzata M; Peciak, Joanna J; Hulas-Bigoszewska, Krystyna K; Winiecka-Klimek, Marta M; Rieske, Piotr P

Publication Date: 2016-01

Variant appearance in text: PTEN: R159S

PubMed Link: 26870252

Variant Present in the following documents:

• Main text
• ol-11-01-0593.pdf

View BVdb publication page

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Whole Exome Sequencing Identifies Frequent Somatic Mutations in Cell-Cell Adhesion Genes in Chinese Patients with Lung Squamous Cell Carcinoma.

Scientific Reports

Li, Chenguang C; Gao, Zhibo Z; Li, Fei F; Li, Xiangchun X; Sun, Yihua Y; Wang, Mengyun M; Li, Dan D; Wang, Rui R; Li, Fuming F; Fang, Rong R; Pan, Yunjian Y; Luo, Xiaoyang X; He, Jing J; Zheng, Liangtao L; Xia, Jufeng J; Qiu, Lixin L; He, Jun J; Ye, Ting T; Zhang, Ruoxin R; He, Minghui M; Zhu, Meiling M; Hu, Haichuan H; Shi, Tingyan T; Zhou, Xiaoyan X; Sun, Menghong M; Tian, Shilin S; Zhou, Yong Y; Wang, Qiaoxiu Q; Chen, Longyun L; Yin, Guangliang G; Lu, Jingya J; Wu, Renhua R; Guo, Guangwu G; Li, Yingrui Y; Hu, Xueda X; Li, Lin L; Asan, ; Wang, Qin Q; Yin, Ye Y; Feng, Qiang Q; Wang, Bin B; Wang, Hang H; Wang, Mingbang M; Yang, Xiaonan X; Zhang, Xiuqing X; Yang, Huanming H; Jin, Li L; Wang, Cun-Yu CY; Ji, Hongbin H; Chen, Haiquan H; Wang, Jun J; Wei, Qingyi Q

Publication Date: 2015-10-27

Variant appearance in text: PTEN: R159S

PubMed Link: 26503331

Variant Present in the following documents:

• srep14237-s6.xls, sheet 1

View BVdb publication page

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Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma.

The Journal Of Clinical Investigation

Kwong, Lawrence N LN; Boland, Genevieve M GM; Frederick, Dennie T DT; Helms, Timothy L TL; Akid, Ahmad T AT; Miller, John P JP; Jiang, Shan S; Cooper, Zachary A ZA; Song, Xingzhi X; Seth, Sahil S; Kamara, Jennifer J; Protopopov, Alexei A; Mills, Gordon B GB; Flaherty, Keith T KT; Wargo, Jennifer A JA; Chin, Lynda L

Publication Date: 2015-04

Variant appearance in text: PTEN: R159S

PubMed Link: 25705882

Variant Present in the following documents:

• Main text

View BVdb publication page

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Molecular characteristics of endometrial cancer coexisting with peritoneal malignant mesothelioma in Li-Fraumeni-like syndrome.

Bmc Cancer

Chao, Angel A; Lai, Chyong-Huey CH; Lee, Yun-Shien YS; Ueng, Shir-Hwa SH; Lin, Chiao-Yun CY; Wang, Tzu-Hao TH

Publication Date: 2015-01-15

Variant appearance in text: PTEN: 477G>T; R159S

PubMed Link: 25588929

Variant Present in the following documents:

View BVdb publication page

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Age-related mutations associated with clonal hematopoietic expansion and malignancies.

Nature Medicine

Xie, Mingchao M; Lu, Charles C; Wang, Jiayin J; McLellan, Michael D MD; Johnson, Kimberly J KJ; Wendl, Michael C MC; McMichael, Joshua F JF; Schmidt, Heather K HK; Yellapantula, Venkata V; Miller, Christopher A CA; Ozenberger, Bradley A BA; Welch, John S JS; Link, Daniel C DC; Walter, Matthew J MJ; Mardis, Elaine R ER; Dipersio, John F JF; Chen, Feng F; Wilson, Richard K RK; Ley, Timothy J TJ; Ding, Li L

Publication Date: 2014-12

Variant appearance in text: PTEN: R159S

PubMed Link: 25326804

Variant Present in the following documents:

• NIHMS630249-supplement-6.xlsx, sheet 1
• NIHMS630249-supplement-5.xlsx, sheet 1

View BVdb publication page

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Stand up to cancer phase Ib study of pan-phosphoinositide-3-kinase inhibitor buparlisib with letrozole in estrogen receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology

Mayer, Ingrid A IA; Abramson, Vandana G VG; Isakoff, Steven J SJ; Forero, Andres A; Balko, Justin M JM; Kuba, María Gabriela MG; Sanders, Melinda E ME; Yap, Jeffrey T JT; Van den Abbeele, Annick D AD; Li, Yisheng Y; Cantley, Lewis C LC; Winer, Eric E; Arteaga, Carlos L CL

Publication Date: 2014-04-20

Variant appearance in text: PTEN: 477G>T; R159S

PubMed Link: 24663045

Variant Present in the following documents:

• Main text

View BVdb publication page

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The integrated landscape of driver genomic alterations in glioblastoma.

Nature Genetics

Frattini, Veronique V; Trifonov, Vladimir V; Chan, Joseph Minhow JM; Castano, Angelica A; Lia, Marie M; Abate, Francesco F; Keir, Stephen T ST; Ji, Alan X AX; Zoppoli, Pietro P; Niola, Francesco F; Danussi, Carla C; Dolgalev, Igor I; Porrati, Paola P; Pellegatta, Serena S; Heguy, Adriana A; Gupta, Gaurav G; Pisapia, David J DJ; Canoll, Peter P; Bruce, Jeffrey N JN; McLendon, Roger E RE; Yan, Hai H; Aldape, Ken K; Finocchiaro, Gaetano G; Mikkelsen, Tom T; Privé, Gilbert G GG; Bigner, Darell D DD; Lasorella, Anna A; Rabadan, Raul R; Iavarone, Antonio A

Publication Date: 2013-10

Variant appearance in text: PTEN: R159S

PubMed Link: 23917401

Variant Present in the following documents:

• NIHMS510851-supplement-3.xlsx, sheet 1

View BVdb publication page

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High accuracy mutation detection in leukemia on a selected panel of cancer genes.

Plos One

Kalender Atak, Zeynep Z; De Keersmaecker, Kim K; Gianfelici, Valentina V; Geerdens, Ellen E; Vandepoel, Roel R; Pauwels, Daphnie D; Porcu, Michaël M; Lahortiga, Idoya I; Brys, Vanessa V; Dirks, Willy G WG; Quentmeier, Hilmar H; Cloos, Jacqueline J; Cuppens, Harry H; Uyttebroeck, Anne A; Vandenberghe, Peter P; Cools, Jan J; Aerts, Stein S

Publication Date: 2012

Variant appearance in text: PTEN: R159S

PubMed Link: 22675565

Variant Present in the following documents:

• pone.0038463.s007.xlsx, sheet 1

View BVdb publication page

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Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research

Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C

Publication Date: 2011-09-01

Variant appearance in text: PTEN: R159S

PubMed Link: 21727090

Variant Present in the following documents:

• supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1

View BVdb publication page

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Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.

Nature Medicine

Palomero, Teresa T; Sulis, Maria Luisa ML; Cortina, Maria M; Real, Pedro J PJ; Barnes, Kelly K; Ciofani, Maria M; Caparros, Esther E; Buteau, Jean J; Brown, Kristy K; Perkins, Sherrie L SL; Bhagat, Govind G; Agarwal, Archana M AM; Basso, Giuseppe G; Castillo, Mireia M; Nagase, Satoru S; Cordon-Cardo, Carlos C; Parsons, Ramon R; Zúñiga-Pflücker, Juan Carlos JC; Dominguez, Maria M; Ferrando, Adolfo A AA

Publication Date: 2007-10

Variant appearance in text: PTEN: R159S

PubMed Link: 17873882

Variant Present in the following documents:

• Main text

View BVdb publication page

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