Publications:

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Emerging roles of i-motif in gene expression and disease treatment.

Frontiers In Pharmacology

Luo, Xiaoqing X; Zhang, Jianye J; Gao, Yue Y; Pan, Weifei W; Yang, Yayuan Y; Li, Xu X; Chen, Lingfei L; Wang, Chang C; Wang, Yuqing Y

Publication Date: 2023

Variant appearance in text: HRAS: G12C

PubMed Link: 37021044

Variant Present in the following documents:

• fphar-14-1136251.pdf

View BVdb publication page

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Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.

Cancer Research Communications

White, Jason A JA; Kaninjing, Ernest T ET; Adeniji, Kayode A KA; Jibrin, Paul P; Obafunwa, John O JO; Ogo, Chidiebere N CN; Mohammed, Faruk F; Popoola, Ademola A; Fatiregun, Omolara A OA; Oluwole, Olabode P OP; Karanam, Balasubramanyam B; Elhussin, Isra I; Ambs, Stefan S; Tang, Wei W; Davis, Melissa M; Polak, Paz P; Campbell, Moray J MJ; Brignole, Kathryn R KR; Rotimi, Solomon O SO; Dean-Colomb, Windy W; Odedina, Folake T FT; Martin, Damali N DN; Yates, Clayton C

Publication Date: 2022-09

Variant appearance in text: N/A

PubMed Link: 36922933

Variant Present in the following documents:

View BVdb publication page

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Genomics-Driven Precision Medicine in Pediatric Solid Tumors.

Cancers

Suthapot, Praewa P; Chiangjong, Wararat W; Chaiyawat, Parunya P; Choochuen, Pongsakorn P; Pruksakorn, Dumnoensun D; Sangkhathat, Surasak S; Hongeng, Suradej S; Anurathapan, Usanarat U; Chutipongtanate, Somchai S

Publication Date: 2023-02-23

Variant appearance in text: HRAS: G12C

PubMed Link: 36900212

Variant Present in the following documents:

• cancers-15-01418.pdf

View BVdb publication page

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BdLT-Seq as a barcode decay-based method to unravel lineage-linked transcriptome plasticity.

Nature Communications

Shlyakhtina, Yelyzaveta Y; Bloechl, Bianca B; Portal, Maximiliano M MM

Publication Date: 2023-02-25

Variant appearance in text: HRAS: G12C

PubMed Link: 36841849

Variant Present in the following documents:

• Main text
• 41467_2023_36744_MOESM6_ESM.xlsx, sheet 8
• 41467_2023_36744_MOESM1_ESM.pdf
• 41467_2023_Article_36744.pdf

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: HRAS: 34G>T; Gly12Cys

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.

Nature Communications

Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI

Publication Date: 2023-02-08

Variant appearance in text: HRAS: 34G>T; G12C

PubMed Link: 36755027

Variant Present in the following documents:

• 41467_2023_36328_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Development of a Novel NGS Methodology for Ultrasensitive Circulating Tumor DNA Detection as a Tool for Early-Stage Breast Cancer Diagnosis.

International Journal Of Molecular Sciences

Jiménez-Rodríguez, Begoña B; Alba-Bernal, Alfonso A; López-López, Esperanza E; Quirós-Ortega, María Elena ME; Carbajosa, Guillermo G; Garrido-Aranda, Alicia A; Álvarez, Martina M; Godoy-Ortiz, Ana A; Queipo-Ortuño, María Isabel MI; Vicioso, Luis L; Díaz-Córdoba, Gema G; Roldán-Díaz, María Dunia MD; Velasco-Suelto, Jesús J; Hernando, Cristina C; Bermejo, Begoña B; Julve-Parreño, Ana A; Lluch, Ana A; Pascual, Javier J; Comino-Méndez, Iñaki I; Alba, Emilio E

Publication Date: 2022-12-21

Variant appearance in text: HRAS: 34G>T; G12C

PubMed Link: 36613590

Variant Present in the following documents:

• ijms-24-00146.pdf

View BVdb publication page

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The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations.

Nature Cancer

Villani, Anita A; Davidson, Scott S; Kanwar, Nisha N; Lo, Winnie W WW; Li, Yisu Y; Cohen-Gogo, Sarah S; Fuligni, Fabio F; Edward, Lisa-Monique LM; Light, Nicholas N; Layeghifard, Mehdi M; Harripaul, Ricardo R; Waldman, Larissa L; Gallinger, Bailey B; Comitani, Federico F; Brunga, Ledia L; Hayes, Reid R; Anderson, Nathaniel D ND; Ramani, Arun K AK; Yuki, Kyoko E KE; Blay, Sasha S; Johnstone, Brittney B; Inglese, Cara C; Hammad, Rawan R; Goudie, Catherine C; Shuen, Andrew A; Wasserman, Jonathan D JD; Venier, Rosemarie E RE; Eliou, Marianne M; Lorenti, Miranda M; Ryan, Carol Ann CA; Braga, Michael M; Gloven-Brown, Meagan M; Han, Jianan J; Montero, Maria M; Spatare, Famida F; Whitlock, James A JA; Scherer, Stephen W SW; Chun, Kathy K; Somerville, Martin J MJ; Hawkins, Cynthia C; Abdelhaleem, Mohamed M; Ramaswamy, Vijay V; Somers, Gino R GR; Kyriakopoulou, Lianna L; Hitzler, Johann J; Shago, Mary M; Morgenstern, Daniel A DA; Tabori, Uri U; Meyn, Stephen S; Irwin, Meredith S MS; Malkin, David D; Shlien, Adam A

Publication Date: 2022-12-30

Variant appearance in text: HRAS: G12C

PubMed Link: 36585449

Variant Present in the following documents:

• 43018_2022_474_MOESM12_ESM.xlsx, sheet 6
• 43018_2022_474_MOESM2_ESM.xlsx, sheet 6
• 43018_2022_474_MOESM3_ESM.xlsx, sheet 6
• 43018_2022_474_MOESM10_ESM.xlsx, sheet 6
• 43018_2022_474_MOESM7_ESM.xlsx, sheet 6

View BVdb publication page

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: HRAS: 34G>T; G12C

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 3
• Table_2.xlsx, sheet 2

View BVdb publication page

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Inhibition of mutant RAS-RAF interaction by mimicking structural and dynamic properties of phosphorylated RAS.

Elife

Ilter, Metehan M; Kaşmer, Ramazan R; Jalalypour, Farzaneh F; Atilgan, Canan C; Topcu, Ozan O; Karakaş, Nihal N; Sensoy, Ozge O

Publication Date: 2022-12-02

Variant appearance in text: HRAS: G12C

PubMed Link: 36458814

Variant Present in the following documents:

• Main text

View BVdb publication page

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: HRAS: G12C

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Predicting Deleterious Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) of HRAS Gene and In Silico Evaluation of Their Structural and Functional Consequences towards Diagnosis and Prognosis of Cancer.

Biology

Chai, Chuan-Yu CY; Maran, Sathiya S; Thew, Hin-Yee HY; Tan, Yong-Chiang YC; Rahman, Nik Mohd Afizan Nik Abd NMANA; Cheng, Wan-Hee WH; Lai, Kok-Song KS; Loh, Jiun-Yan JY; Yap, Wai-Sum WS

Publication Date: 2022-11-02

Variant appearance in text: rs104894229

PubMed Link: 36358305

Variant Present in the following documents:

• biology-11-01604.pdf

View BVdb publication page

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Increased osteoclastogenesis contributes to bone loss in the Costello syndrome Hras G12V mouse model.

Frontiers In Cell And Developmental Biology

Nandi, Sayantan S; Chennappan, Saravanakkumar S; Andrasch, Yannik Y; Fidan, Miray M; Engler, Melanie M; Ahmad, Mubashir M; Tuckermann, Jan P JP; Zenker, Martin M; Cirstea, Ion Cristian IC

Publication Date: 2022

Variant appearance in text: HRAS: G12C

PubMed Link: 36330334

Variant Present in the following documents:

• fcell-10-1000575.pdf

View BVdb publication page

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IntegralVac: A Machine Learning-Based Comprehensive Multivalent Epitope Vaccine Design Method.

Vaccines

Suri, Sadhana S; Dakshanamurthy, Sivanesan S

Publication Date: 2022-10-08

Variant appearance in text: HRAS: G12C

PubMed Link: 36298543

Variant Present in the following documents:

• Main text
• vaccines-10-01678.pdf

View BVdb publication page

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The mutational landscape of cancer's vulnerability to ionizing radiation.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Gopal, Priyanka P; Yard, Brian D BD; Petty, Aaron A; Lal, Jessica C JC; Bera, Titas K TK; Hoang, Trung Q TQ; Buhimschi, Alexandru B AB; Abazeed, Mohamed E ME

Publication Date: 2022-10-12

Variant appearance in text: HRAS: G12C

PubMed Link: 36222846

Variant Present in the following documents:

• ccr-22-1914_supplementary_data_2_suppds2.xlsx, sheet 1
• ccr-22-1914_supplementary_data_3_suppds3.xlsx, sheet 1

View BVdb publication page

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Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications

Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A

Publication Date: 2022-07-13

Variant appearance in text: HRAS: 34G>T; Gly12Cys; rs104894229

PubMed Link: 35831314

Variant Present in the following documents:

• 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3

View BVdb publication page

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: HRAS: G12C

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

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Combined exome and transcriptome sequencing of non-muscle-invasive bladder cancer: associations between genomic changes, expression subtypes, and clinical outcomes.

Genome Medicine

Goel, Anshita A; Ward, Douglas G DG; Noyvert, Boris B; Yu, Minghao M; Gordon, Naheema S NS; Abbotts, Ben B; Colbourne, John K JK; Kissane, Stephen S; James, Nicholas D ND; Zeegers, Maurice P MP; Cheng, Kar Keung KK; Cazier, Jean-Baptiste JB; Whalley, Celina M CM; Beggs, Andrew D AD; Palles, Claire C; Arnold, Roland R; Bryan, Richard T RT

Publication Date: 2022-06-03

Variant appearance in text: HRAS: 34G>T; Gly12Cys; rs104894229

PubMed Link: 35655252

Variant Present in the following documents:

• 13073_2022_1056_MOESM1_ESM.xlsx, sheet 3

View BVdb publication page

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Delineating the RAS Conformational Landscape.

Cancer Research

Parker, Mitchell I MI; Meyer, Joshua E JE; Golemis, Erica A EA; Dunbrack, Roland L RL

Publication Date: 2022-07-05

Variant appearance in text: HRAS: G12C

PubMed Link: 35536216

Variant Present in the following documents:

• can-22-0804_supplementary_datasets_s1-s4_suppsds1-sds4.xlsx, sheet 1

View BVdb publication page

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KRAS is vulnerable to reversible switch-II pocket engagement in cells.

Nature Chemical Biology

Vasta, James D JD; Peacock, D Matthew DM; Zheng, Qinheng Q; Walker, Joel A JA; Zhang, Ziyang Z; Zimprich, Chad A CA; Thomas, Morgan R MR; Beck, Michael T MT; Binkowski, Brock F BF; Corona, Cesear R CR; Robers, Matthew B MB; Shokat, Kevan M KM

Publication Date: 2022-06

Variant appearance in text: HRAS: G12C

PubMed Link: 35314814

Variant Present in the following documents:

• 41589_2022_985_MOESM3_ESM.xlsx, sheet 24

View BVdb publication page

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Deleterious mutations in esophageal carcinoma cuniculatum detected by next generation sequencing.

International Journal Of Clinical And Experimental Pathology

Yin, Feng F; Wang, Kai K; Hu, Ming M; Starostik, Petr P; Newsom, Kimberly J KJ; Liu, Xiuli X

Publication Date: 2022

Variant appearance in text: HRAS: 34G>T; Gly12Cys

PubMed Link: 35145582

Variant Present in the following documents:

• Main text

View BVdb publication page

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Stabilization of the RAS:PDE6D Complex Is a Novel Strategy to Inhibit RAS Signaling.

Journal Of Medicinal Chemistry

Yelland, Tamas T; Garcia, Esther E; Parry, Charles C; Kowalczyk, Dominika D; Wojnowska, Marta M; Gohlke, Andrea A; Zalar, Matja M; Cameron, Kenneth K; Goodwin, Gillian G; Yu, Qing Q; Zhu, Peng-Cheng PC; ElMaghloob, Yasmin Y; Pugliese, Angelo A; Archibald, Lewis L; Jamieson, Andrew A; Chen, Yong Xiang YX; McArthur, Duncan D; Bower, Justin J; Ismail, Shehab S

Publication Date: 2022-02-10

Variant appearance in text: HRAS: G12C

PubMed Link: 35104933

Variant Present in the following documents:

• Main text

View BVdb publication page

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Stabilization of the RAS:PDE6D Complex Is a Novel Strategy to Inhibit RAS Signaling.

Journal Of Medicinal Chemistry

Yelland, Tamas T; Garcia, Esther E; Parry, Charles C; Kowalczyk, Dominika D; Wojnowska, Marta M; Gohlke, Andrea A; Zalar, Matja M; Cameron, Kenneth K; Goodwin, Gillian G; Yu, Qing Q; Zhu, Peng-Cheng PC; ElMaghloob, Yasmin Y; Pugliese, Angelo A; Archibald, Lewis L; Jamieson, Andrew A; Chen, Yong Xiang YX; McArthur, Duncan D; Bower, Justin J; Ismail, Shehab S

Publication Date: 2022-02-01

Variant appearance in text: HRAS: G12C

PubMed Link: 35104933

Variant Present in the following documents:

• Main text

View BVdb publication page

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KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One

Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW

Publication Date: 2022

Variant appearance in text: rs104894229

PubMed Link: 35081118

Variant Present in the following documents:

• pone.0251286.s005.xlsx, sheet 8

View BVdb publication page

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KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One

Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW

Publication Date: 2022

Variant appearance in text: rs104894229

PubMed Link: 35081118

Variant Present in the following documents:

• pone.0251286.s005.xlsx, sheet 8

View BVdb publication page

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A New Epitope Selection Method: Application to Design a Multi-Valent Epitope Vaccine Targeting HRAS Oncogene in Squamous Cell Carcinoma.

Vaccines

Savsani, Kush K; Jabbour, Gabriel G; Dakshanamurthy, Sivanesan S

Publication Date: 2021-12-31

Variant appearance in text: HRAS: G12C

PubMed Link: 35062725

Variant Present in the following documents:

• Main text

View BVdb publication page

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A New Epitope Selection Method: Application to Design a Multi-Valent Epitope Vaccine Targeting HRAS Oncogene in Squamous Cell Carcinoma.

Vaccines

Savsani, Kush K; Jabbour, Gabriel G; Dakshanamurthy, Sivanesan S

Publication Date: 2021-12-31

Variant appearance in text: HRAS: G12C

PubMed Link: 35062725

Variant Present in the following documents:

• Main text

View BVdb publication page

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Recent Developments in Targeting RAS Downstream Effectors for RAS-Driven Cancer Therapy.

Molecules (Basel, Switzerland)

Tatli, Ozge O; Dinler Doganay, Gizem G

Publication Date: 2021-12-14

Variant appearance in text: HRAS: G12C

PubMed Link: 34946644

Variant Present in the following documents:

• Main text
• molecules-26-07561.pdf

View BVdb publication page

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Recent Developments in Targeting RAS Downstream Effectors for RAS-Driven Cancer Therapy.

Molecules (Basel, Switzerland)

Tatli, Ozge O; Dinler Doganay, Gizem G

Publication Date: 2021-12-14

Variant appearance in text: HRAS: G12C

PubMed Link: 34946644

Variant Present in the following documents:

• Main text
• molecules-26-07561.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: HRAS: G12C

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Gene Mutation Analysis in Papillary Thyroid Carcinoma Using a Multi-Gene Panel in China.

International Journal Of General Medicine

Wang, Qiang Q; Zhao, Ning N; Zhang, Jun J

Publication Date: 2021

Variant appearance in text: HRAS: G12C

PubMed Link: 34511996

Variant Present in the following documents:

• Main text
• ijgm-14-5139.pdf

View BVdb publication page

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Longitudinal detection of somatic mutations in saliva and plasma for the surveillance of oral squamous cell carcinomas.

Plos One

Cui, Ying Y; Kim, Hae-Suk HS; Cho, Eunae Sandra ES; Han, Dawool D; Park, Jung Ah JA; Park, Ju Yeong JY; Nam, Woong W; Kim, Hyung Jun HJ; Cha, In-Ho IH; Cha, Yong Hoon YH

Publication Date: 2021

Variant appearance in text: HRAS: 34G>T; Gly12Cys

PubMed Link: 34478472

Variant Present in the following documents:

• pone.0256979.s002.xlsx, sheet 1

View BVdb publication page

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The landscape of driver mutations in cutaneous squamous cell carcinoma.

Npj Genomic Medicine

Chang, Darwin D; Shain, A Hunter AH

Publication Date: 2021-07-16

Variant appearance in text: HRAS: G12C

PubMed Link: 34272401

Variant Present in the following documents:

• 41525_2021_226_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Genomic Landscape of Head and Neck Squamous Cell Carcinoma Across Different Anatomic Sites in Chinese Population.

Frontiers In Genetics

Ju, Yunhe Y; Wu, Xingrao X; Wang, Huizhen H; Li, Bin B; Long, Qing Q; Zhang, Dadong D; Chen, Hao H; Xiao, Nianqing N; Li, Fugen F; Zhang, Shiwen S; Yang, Shenggang S

Publication Date: 2021

Variant appearance in text: HRAS: G12C

PubMed Link: 34194478

Variant Present in the following documents:

• Data_Sheet_1.xlsx, sheet 6

View BVdb publication page

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Improvement of Neoantigen Identification Through Convolution Neural Network.

Frontiers In Immunology

Hao, Qing Q; Wei, Ping P; Shu, Yang Y; Zhang, Yi-Guan YG; Xu, Heng H; Zhao, Jun-Ning JN

Publication Date: 2021

Variant appearance in text: HRAS: G12C

PubMed Link: 34113354

Variant Present in the following documents:

• Table_1.xlsx, sheet 3

View BVdb publication page

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Host pharmacogenetic factors that may affect liver neoplasm incidence upon using direct-acting antivirals for treating hepatitis C infection.

Heliyon

Zidan, Ahmad M AM; Saad, Eman A EA; Ibrahim, Nasser E NE; Hashem, Medhat H MH; Mahmoud, Amal A; Hemeida, Alaa A AA

Publication Date: 2021-05

Variant appearance in text: rs104894229

PubMed Link: 34013078

Variant Present in the following documents:

• Main text

View BVdb publication page

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Spatially interacting phosphorylation sites and mutations in cancer.

Nature Communications

Huang, Kuan-Lin KL; Scott, Adam D AD; Zhou, Daniel Cui DC; Wang, Liang-Bo LB; Weerasinghe, Amila A; Elmas, Abdulkadir A; Liu, Ruiyang R; Wu, Yige Y; Wendl, Michael C MC; Wyczalkowski, Matthew A MA; Baral, Jessika J; Sengupta, Sohini S; Lai, Chin-Wen CW; Ruggles, Kelly K; Payne, Samuel H SH; Raphael, Benjamin B; Fenyö, David D; Chen, Ken K; Mills, Gordon G; Ding, Li L

Publication Date: 2021-04-19

Variant appearance in text: HRAS: G12C

PubMed Link: 33875650

Variant Present in the following documents:

• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 6
• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Comprehensive omic characterization of breast cancer in Mexican-Hispanic women.

Nature Communications

Romero-Cordoba, Sandra L SL; Salido-Guadarrama, Ivan I; Rebollar-Vega, Rosa R; Bautista-Piña, Veronica V; Dominguez-Reyes, Carlos C; Tenorio-Torres, Alberto A; Villegas-Carlos, Felipe F; Fernández-López, Juan C JC; Uribe-Figueroa, Laura L; Alfaro-Ruiz, Luis L; Hidalgo-Miranda, Alfredo A

Publication Date: 2021-04-14

Variant appearance in text: HRAS: G12C

PubMed Link: 33854067

Variant Present in the following documents:

• 41467_2021_22478_MOESM8_ESM.xlsx, sheet 3

View BVdb publication page

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RAS Nanoclusters: Dynamic Signaling Platforms Amenable to Therapeutic Intervention.

Biomolecules

Van, Que N QN; Prakash, Priyanka P; Shrestha, Rebika R; Balius, Trent E TE; Turbyville, Thomas J TJ; Stephen, Andrew G AG

Publication Date: 2021-03-03

Variant appearance in text: HRAS: G12C

PubMed Link: 33802474

Variant Present in the following documents:

• Main text
• biomolecules-11-00377.pdf

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: HRAS: 34G>T; G12C

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.

Nature Communications

Hartlieb, Sabine A SA; Sieverling, Lina L; Nadler-Holly, Michal M; Ziehm, Matthias M; Toprak, Umut H UH; Herrmann, Carl C; Ishaque, Naveed N; Okonechnikov, Konstantin K; Gartlgruber, Moritz M; Park, Young-Gyu YG; Wecht, Elisa Maria EM; Savelyeva, Larissa L; Henrich, Kai-Oliver KO; Rosswog, Carolina C; Fischer, Matthias M; Hero, Barbara B; Jones, David T W DTW; Pfaff, Elke E; Witt, Olaf O; Pfister, Stefan M SM; Volckmann, Richard R; Koster, Jan J; Kiesel, Katharina K; Rippe, Karsten K; Taschner-Mandl, Sabine S; Ambros, Peter P; Brors, Benedikt B; Selbach, Matthias M; Feuerbach, Lars L; Westermann, Frank F

Publication Date: 2021-02-24

Variant appearance in text: rs104894229

PubMed Link: 33627664

Variant Present in the following documents:

• 41467_2021_21247_MOESM10_ESM.xlsx, sheet 1

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Evaluation of the Oncomine Pan-Cancer Cell-Free Assay for Analyzing Circulating Tumor DNA in the Cerebrospinal Fluid in Patients with Central Nervous System Malignancies.

The Journal Of Molecular Diagnostics : Jmd

Shah, Mauli M; Takayasu, Takeshi T; Zorofchian Moghadamtousi, Soheil S; Arevalo, Octavio O; Chen, Melissa M; Lan, Chieh C; Duose, Dzifa D; Hu, Peter P; Zhu, Jay-Jiguang JJ; Roy-Chowdhuri, Sinchita S; Riascos, Roy F RF; Chen, Hui H; Luthra, Rajyalakshmi R; Esquenazi, Yoshua Y; Ballester, Leomar Y LY

Publication Date: 2021-02

Variant appearance in text: HRAS: G12C

PubMed Link: 33531134

Variant Present in the following documents:

• Main text

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: HRAS: 34G>T; G12C

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM9_ESM.xlsx, sheet 1
• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
• 41467_2020_20162_MOESM10_ESM.xlsx, sheet 1

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Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.

Cancer Medicine

Sivapiragasam, Abirami A; Ashok Kumar, Prashanth P; Sokol, Ethan S ES; Albacker, Lee A LA; Killian, Jonathan K JK; Ramkissoon, Shakti H SH; Huang, Richard S P RSP; Severson, Eric A EA; Brown, Charlotte A CA; Danziger, Natalie N; McGregor, Kimberly K; Ross, Jeffrey S JS

Publication Date: 2021-01

Variant appearance in text: HRAS: G12C

PubMed Link: 33314633

Variant Present in the following documents:

• CAM4-10-53-s003.xlsx, sheet 1
• CAM4-10-53-s002.xlsx, sheet 1

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Integrated molecular drivers coordinate biological and clinical states in melanoma.

Nature Genetics

Conway, Jake R JR; Dietlein, Felix F; Taylor-Weiner, Amaro A; AlDubayan, Saud S; Vokes, Natalie N; Keenan, Tanya T; Reardon, Brendan B; He, Meng Xiao MX; Margolis, Claire A CA; Weirather, Jason L JL; Haq, Rizwan R; Schilling, Bastian B; Stephen Hodi, F F; Schadendorf, Dirk D; Liu, David D; Van Allen, Eliezer M EM

Publication Date: 2020-12

Variant appearance in text: rs104894229

PubMed Link: 33230298

Variant Present in the following documents:

• NIHMS1637640-supplement-SuppData1.xlsx, sheet 1

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Comparing cell-free circulating tumor DNA mutational profiles of disease-free and nonresponders patients with oropharyngeal squamous cell carcinoma.

Laryngoscope Investigative Otolaryngology

Khandelwal, Alok R AR; Greer, Adam H AH; Hamiter, Mickie M; Fermin, Janmaris Marin JM; McMullen, Thomas T; Moore-Medlin, Tara T; Mills, Glenn G; Flores, Jose M JM; Yin, Hong H; Nathan, Cherie-Ann O CO

Publication Date: 2020-10

Variant appearance in text: HRAS: Gly12Cys

PubMed Link: 33134534

Variant Present in the following documents:

• Main text
• LIO2-5-868.pdf

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Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports

Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O

Publication Date: 2020-10-13

Variant appearance in text: rs104894229

PubMed Link: 33051506

Variant Present in the following documents:

• 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1

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Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway.

Elife

Chai, Annie Wai Yeeng AWY; Yee, Pei San PS; Price, Stacey S; Yee, Shi Mun SM; Lee, Hui Mei HM; Tiong, Vivian Kh VK; Gonçalves, Emanuel E; Behan, Fiona M FM; Bateson, Jessica J; Gilbert, James J; Tan, Aik Choon AC; McDermott, Ultan U; Garnett, Mathew J MJ; Cheong, Sok Ching SC

Publication Date: 2020-09-29

Variant appearance in text: HRAS: G12C

PubMed Link: 32990596

Variant Present in the following documents:

• Main text
• elife-57761-supp4.xlsx, sheet 1
• elife-57761.pdf

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Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports

Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA

Publication Date: 2020-09-21

Variant appearance in text: HRAS: G12C

PubMed Link: 32958805

Variant Present in the following documents:

• 41598_2020_72404_MOESM2_ESM.xlsx, sheet 2

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Clinicopathological and Molecular Differences Between Gastric-type Mucinous Carcinoma and Usual-type Endocervical Adenocarcinoma of the Uterine Cervix.

Cancer Genomics & Proteomics

Jung, Hera H; Bae, Go Eun GE; Kim, Hye Min HM; Kim, Hyun-Soo HS

Publication Date: 2020

Variant appearance in text: HRAS: 34G>T; Gly12Cys

PubMed Link: 32859641

Variant Present in the following documents:

• Main text

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A risk-associated Active transcriptome phenotype expressed by histologically normal human breast tissue and linked to a pro-tumorigenic adipocyte population.

Breast Cancer Research : Bcr

Kang, Taekyu T; Yau, Christina C; Wong, Christopher K CK; Sanborn, John Z JZ; Newton, Yulia Y; Vaske, Charlie C; Benz, Stephen C SC; Krings, Gregor G; Camarda, Roman R; Henry, Jill E JE; Stuart, Josh J; Powell, Mark M; Benz, Christopher C CC

Publication Date: 2020-07-31

Variant appearance in text: HRAS: 34G>T; G12C

PubMed Link: 32736587

Variant Present in the following documents:

• 13058_2020_1322_MOESM3_ESM.xlsx, sheet 1

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Identification of relevant genetic alterations in cancer using topological data analysis.

Nature Communications

Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG

Publication Date: 2020-07-30

Variant appearance in text: HRAS: G12C

PubMed Link: 32732999

Variant Present in the following documents:

• 41467_2020_17659_MOESM3_ESM.xls, sheet 1

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Tipifarnib as a Precision Therapy for HRAS-Mutant Head and Neck Squamous Cell Carcinomas.

Molecular Cancer Therapeutics

Gilardi, Mara M; Wang, Zhiyong Z; Proietto, Marco M; Chillà, Anastasia A; Calleja-Valera, Juan Luis JL; Goto, Yusuke Y; Vanoni, Marco M; Janes, Matthew R MR; Mikulski, Zbigniew Z; Gualberto, Antonio A; Molinolo, Alfredo A AA; Ferrara, Napoleone N; Gutkind, J Silvio JS; Burrows, Francis F

Publication Date: 2020-09

Variant appearance in text: HRAS: G12C

PubMed Link: 32727882

Variant Present in the following documents:

• Main text

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Immunohistochemistry-Based Taxonomical Classification of Bladder Cancer Predicts Response to Neoadjuvant Chemotherapy.

Cancers

Font, Albert A; Domènech, Montserrat M; Benítez, Raquel R; Rava, Marta M; Marqués, Miriam M; Ramírez, José L JL; Pineda, Silvia S; Domínguez-Rodríguez, Sara S; Gago, José L JL; Badal, Josep J; Carrato, Cristina C; López, Héctor H; Quer, Ariadna A; Castellano, Daniel D; Malats, Núria N; Real, Francisco X FX

Publication Date: 2020-07-03

Variant appearance in text: HRAS: G12C

PubMed Link: 32635360

Variant Present in the following documents:

• Main text
• cancers-12-01784.pdf

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mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports

Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM

Publication Date: 2020-06-23

Variant appearance in text: HRAS: G12C

PubMed Link: 32579932

Variant Present in the following documents:

• mmc5.xlsx, sheet 3

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Inhibition of NRAS Signaling in Melanoma through Direct Depalmitoylation Using Amphiphilic Nucleophiles.

Acs Chemical Biology

Vora, Hetika D HD; Johnson, Mai M; Brea, Roberto J RJ; Rudd, Andrew K AK; Devaraj, Neal K NK

Publication Date: 2020-08-21

Variant appearance in text: HRAS: G12C

PubMed Link: 32568509

Variant Present in the following documents:

• Main text

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: HRAS: G12C

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

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Dual-molecular barcode sequencing detects rare variants in tumor and cell free DNA in plasma.

Scientific Reports

Hirotsu, Yosuke Y; Otake, Sotaro S; Ohyama, Hiroshi H; Amemiya, Kenji K; Higuchi, Rumi R; Oyama, Toshio T; Mochizuki, Hitoshi H; Goto, Taichiro T; Omata, Masao M

Publication Date: 2020-02-25

Variant appearance in text: HRAS: 34G>T; G12C

PubMed Link: 32099048

Variant Present in the following documents:

• Main text

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The paradox of cancer genes in non-malignant conditions: implications for precision medicine.

Genome Medicine

Adashek, Jacob J JJ; Kato, Shumei S; Lippman, Scott M SM; Kurzrock, Razelle R

Publication Date: 2020-02-17

Variant appearance in text: HRAS: G12C

PubMed Link: 32066498

Variant Present in the following documents:

• Main text
• 13073_2020_Article_714.pdf

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CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG.

Nature Communications

Liu, Zhihui Z; Zhang, Xiyuan X; Lei, Haiyan H; Lam, Norris N; Carter, Sakereh S; Yockey, Oliver O; Xu, Max M; Mendoza, Arnulfo A; Hernandez, Edjay R ER; Wei, Jun S JS; Khan, Javed J; Yohe, Marielle E ME; Shern, Jack F JF; Thiele, Carol J CJ

Publication Date: 2020-02-14

Variant appearance in text: HRAS: G12C

PubMed Link: 32060262

Variant Present in the following documents:

• Main text

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The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer.

Oncogene

Saliakoura, Maria M; Reynoso-Moreno, Inés I; Pozzato, Chiara C; Rossi Sebastiano, Matteo M; Galié, Mirco M; Gertsch, Jürg J; Konstantinidou, Georgia G

Publication Date: 2020-04

Variant appearance in text: HRAS: 34G>T; G12C

PubMed Link: 32034305

Variant Present in the following documents:

• 41388_2020_1196_MOESM2_ESM.xls, sheet 1

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RAS pathway influences the number of melanocytic nevi in cardiofaciocutaneous and Costello syndromes.

Journal Of The American Academy Of Dermatology

Kiuru, Maija M; Urban, Jennifer J; Zhu, Guannan G; Rybak, Iryna I; Terrell, Jessica R JR; Qi, Lihong L; McPherson, John D JD; Marghoob, Ashfaq A AA; Rauen, Katherine A KA

Publication Date: 2020-05

Variant appearance in text: HRAS: G12C

PubMed Link: 32001297

Variant Present in the following documents:

• Main text

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Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology

Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M

Publication Date: 2020-01-07

Variant appearance in text: HRAS: G12C

PubMed Link: 31925297

Variant Present in the following documents:

• 42003_2019_736_MOESM13_ESM.xlsx, sheet 1
• 42003_2019_736_MOESM4_ESM.xlsx, sheet 1
• 42003_2019_736_MOESM3_ESM.xlsx, sheet 1
• 42003_2019_736_MOESM10_ESM.xlsx, sheet 1

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