KRAS c.50G>A ;(p.S17N)

Variant ID: 12-25398269-C-T

NM_004985.3(KRAS):c.50G>A;(p.S17N)

This variant was identified in 48 publications

View GRCh38 version.




Publications:


KRAS Mutations Are Associated with Shortened Survival in Patients with Epithelioid Malignant Pleural Mesothelioma.

Cancers
Vannucchi, Margherita M; Pennati, Veronica V; Mencaroni, Clelia C; Defraia, Chiara C; Bardhi, Ledi L; Castiglione, Francesca F; Bellan, Cristiana C; Comin, Camilla Eva CE
Publication Date: 2023-03-30

Variant appearance in text: KRAS: S17N
PubMed Link: 37046732
Variant Present in the following documents:
  • Main text
  • cancers-15-02072.pdf
View BVdb publication page



Multiomic analysis of papillary thyroid cancers identifies BAIAP2L1-BRAF fusion and requirement of TRIM25, PDE5A and PKCδ for tumorigenesis.

Molecular Cancer
Renaud, Emilie E; Riegel, Kristina K; Romero, Rossana R; Suryamohan, Kushal K; Distler, Ute U; Tenzer, Stefan S; Schad, Arno A; Musholt, Thomas J TJ; Rajalingam, Krishnaraj K
Publication Date: 2022-10-10

Variant appearance in text: KRAS: S17N
PubMed Link: 36217175
Variant Present in the following documents:
  • Main text
  • 12943_2022_Article_1665.pdf
  • 12943_2022_1665_MOESM1_ESM.pdf
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Oncogenic RAS commandeers amino acid sensing machinery to aberrantly activate mTORC1 in multiple myeloma.

Nature Communications
Yang, Yandan Y; Bolomsky, Arnold A; Oellerich, Thomas T; Chen, Ping P; Ceribelli, Michele M; Häupl, Björn B; Wright, George W GW; Phelan, James D JD; Huang, Da Wei DW; Lord, James W JW; Van Winkle, Callie K CK; Yu, Xin X; Wisniewski, Jan J; Wang, James Q JQ; Tosto, Frances A FA; Beck, Erin E; Wilson, Kelli K; McKnight, Crystal C; Travers, Jameson J; Klumpp-Thomas, Carleen C; Smith, Grace A GA; Pittaluga, Stefania S; Maric, Irina I; Kazandjian, Dickran D; Thomas, Craig J CJ; Young, Ryan M RM
Publication Date: 2022-09-17

Variant appearance in text: KRAS: S17N
PubMed Link: 36115844
Variant Present in the following documents:
  • Main text
  • 41467_2022_33142_MOESM3_ESM.xlsx, sheet 60
View BVdb publication page



iRhom2 regulates ERBB signalling to promote KRAS-driven tumour growth of lung cancer cells.

Journal Of Cell Science
Sieber, Boris B; Lu, Fangfang F; Stribbling, Stephen M SM; Grieve, Adam G AG; Ryan, Anderson J AJ; Freeman, Matthew M
Publication Date: 2022-09-01

Variant appearance in text: KRAS: S17N
PubMed Link: 35971826
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Proteomic Approach Identifies Isoform-Specific and Nucleotide-Dependent RAS Interactions.

Molecular & Cellular Proteomics : Mcp
Miller, Seth P SP; Maio, George G; Zhang, Xiaoyu X; Badillo Soto, Felix S FS; Zhu, Julia J; Ramirez, Stephen Z SZ; Lin, Hening H
Publication Date: 2022-08

Variant appearance in text: KRAS: S17N
PubMed Link: 35839996
Variant Present in the following documents:
  • mmc1.pdf
View BVdb publication page



Response prediction in patients with gastric and esophagogastric adenocarcinoma under neoadjuvant chemotherapy using targeted gene expression analysis and next-generation sequencing in pre-therapeutic biopsies.

Journal Of Cancer Research And Clinical Oncology
Kleo, Karsten K; Jovanovic, Vladimir M VM; Arndold, Alexander A; Lehmann, Annika A; Lammert, Hedwig H; Berg, Erika E; Harloff, Hannah H; Treese, Christoph C; Hummel, Michael M; Daum, Severin S
Publication Date: 2022-03-05

Variant appearance in text: KRAS: 50G>A
PubMed Link: 35246724
Variant Present in the following documents:
  • 432_2022_3944_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis.

Nature Communications
Ramirez, Nora-Guadalupe P NP; Lee, Jeon J; Zheng, Yue Y; Li, Lianbo L; Dennis, Bryce B; Chen, Didi D; Challa, Ashwini A; Planelles, Vicente V; Westover, Kenneth D KD; Alto, Neal M NM; D'Orso, Iván I
Publication Date: 2022-03-01

Variant appearance in text: KRAS: S17N
PubMed Link: 35232997
Variant Present in the following documents:
  • Main text
  • 41467_2022_Article_28772.pdf
View BVdb publication page



Deciphering cell signaling networks with massively multiplexed biosensor barcoding.

Cell
Yang, Jr-Ming JM; Chi, Wei-Yu WY; Liang, Jessica J; Takayanagi, Saki S; Iglesias, Pablo A PA; Huang, Chuan-Hsiang CH
Publication Date: 2021-12-09

Variant appearance in text: KRAS: S17N
PubMed Link: 34838160
Variant Present in the following documents:
  • Main text
  • nihms-1756273.pdf
View BVdb publication page



Deciphering cell signaling networks with massively multiplexed biosensor barcoding.

Cell
Yang, Jr-Ming JM; Chi, Wei-Yu WY; Liang, Jessica J; Takayanagi, Saki S; Iglesias, Pablo A PA; Huang, Chuan-Hsiang CH
Publication Date: 2021-12-09

Variant appearance in text: KRAS: S17N
PubMed Link: 34838160
Variant Present in the following documents:
  • Main text
  • nihms-1756273.pdf
View BVdb publication page



Oncogenic KRAS is dependent upon an EFR3A-PI4KA signaling axis for potent tumorigenic activity.

Nature Communications
Adhikari, Hema H; Kattan, Walaa E WE; Kumar, Shivesh S; Zhou, Pei P; Hancock, John F JF; Counter, Christopher M CM
Publication Date: 2021-09-09

Variant appearance in text: KRAS: S17N
PubMed Link: 34504076
Variant Present in the following documents:
  • Main text
  • 41467_2021_Article_25523.pdf
  • 41467_2021_25523_MOESM2_ESM.pdf
View BVdb publication page



RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Castel, Pau P; Dharmaiah, Srisathiyanarayanan S; Sale, Matthew J MJ; Messing, Simon S; Rizzuto, Gabrielle G; Cuevas-Navarro, Antonio A; Cheng, Alice A; Trnka, Michael J MJ; Urisman, Anatoly A; Esposito, Dominic D; Simanshu, Dhirendra K DK; McCormick, Frank F
Publication Date: 2021-08-17

Variant appearance in text: KRAS: S17N
PubMed Link: 34380736
Variant Present in the following documents:
  • Main text
View BVdb publication page



Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen.

Nature Communications
Giubilaro, Jenna J; Schuetz, Doris A DA; Stepniewski, Tomasz M TM; Namkung, Yoon Y; Khoury, Etienne E; Lara-Márquez, Mónica M; Campbell, Shirley S; Beautrait, Alexandre A; Armando, Sylvain S; Radresa, Olivier O; Duchaine, Jean J; Lamarche-Vane, Nathalie N; Claing, Audrey A; Selent, Jana J; Bouvier, Michel M; Marinier, Anne A; Laporte, Stéphane A SA
Publication Date: 2021-08-03

Variant appearance in text: KRAS: S17N
PubMed Link: 34344896
Variant Present in the following documents:
  • 41467_2021_24968_MOESM2_ESM.pdf
View BVdb publication page



Comprehensive molecular profiling of pulmonary pleomorphic carcinoma.

Npj Precision Oncology
Nagano, Masaaki M; Kohsaka, Shinji S; Hayashi, Takuo T; Ueno, Toshihide T; Kojima, Shinya S; Shinozaki-Ushiku, Aya A; Morita, Shigeki S; Tsuda, Masumi M; Tanaka, Shinya S; Shinohara, Toshiya T; Omori, Yuko Y; Sugaya, Fumiko F; Kato, Hiroaki H; Narita, Yoshiaki Y; Nakajima, Jun J; Suzuki, Kenji K; Takamochi, Kazuya K; Mano, Hiroyuki H
Publication Date: 2021-06-22

Variant appearance in text: KRAS: 50G>A
PubMed Link: 34158601
Variant Present in the following documents:
  • 41698_2021_201_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



RAS Nanoclusters: Dynamic Signaling Platforms Amenable to Therapeutic Intervention.

Biomolecules
Van, Que N QN; Prakash, Priyanka P; Shrestha, Rebika R; Balius, Trent E TE; Turbyville, Thomas J TJ; Stephen, Andrew G AG
Publication Date: 2021-03-03

Variant appearance in text: KRAS: S17N
PubMed Link: 33802474
Variant Present in the following documents:
  • Main text
  • biomolecules-11-00377.pdf
View BVdb publication page



Mechanisms of Ras Membrane Organization and Signaling: Ras Rocks Again.

Biomolecules
Abankwa, Daniel D; Gorfe, Alemayehu A AA
Publication Date: 2020-11-06

Variant appearance in text: K-Ras4B: S17N
PubMed Link: 33172116
Variant Present in the following documents:
  • Main text
  • biomolecules-10-01522.pdf
View BVdb publication page



The RAS-interacting chaperone UNC119 drives the RASSF6-MDM2-p53 axis and antagonizes RAS-mediated malignant transformation.

The Journal Of Biological Chemistry
Shimizu, Takanobu T; Nakamura, Takeshi T; Inaba, Hironori H; Iwasa, Hiroaki H; Maruyama, Junichi J; Arimoto-Matsuzaki, Kyoko K; Nakata, Takao T; Nishina, Hiroshi H; Hata, Yutaka Y
Publication Date: 2020-08-07

Variant appearance in text: KRAS: S17N
PubMed Link: 32554467
Variant Present in the following documents:
  • Main text
View BVdb publication page



Split Intein-Mediated Protein Ligation for detecting protein-protein interactions and their inhibition.

Nature Communications
Yao, Zhong Z; Aboualizadeh, Farzaneh F; Kroll, Jason J; Akula, Indira I; Snider, Jamie J; Lyakisheva, Anna A; Tang, Priscilla P; Kotlyar, Max M; Jurisica, Igor I; Boxem, Mike M; Stagljar, Igor I
Publication Date: 2020-05-15

Variant appearance in text: KRAS: S17N
PubMed Link: 32415080
Variant Present in the following documents:
  • Main text
  • 41467_2020_Article_16299.pdf
View BVdb publication page



Galectin-8 binds to the Farnesylated C-terminus of K-Ras4B and Modifies Ras/ERK Signaling and Migration in Pancreatic and Lung Carcinoma Cells.

Cancers
Meinohl, Christopher C; Barnard, Sarah J SJ; Fritz-Wolf, Karin K; Unger, Monika M; Porr, Andreea A; Heipel, Marisa M; Wirth, Stefanie S; Madlung, Johannes J; Nordheim, Alfred A; Menke, Andre A; Becker, Katja K; Giehl, Klaudia K
Publication Date: 2019-12-20

Variant appearance in text: K-Ras4B: S17N
PubMed Link: 31861875
Variant Present in the following documents:
  • Main text
  • cancers-12-00030.pdf
View BVdb publication page



KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe.

Nature Communications
Bery, Nicolas N; Legg, Sandrine S; Debreczeni, Judit J; Breed, Jason J; Embrey, Kevin K; Stubbs, Christopher C; Kolasinska-Zwierz, Paulina P; Barrett, Nathalie N; Marwood, Rose R; Watson, Jo J; Tart, Jon J; Overman, Ross R; Miller, Ami A; Phillips, Christopher C; Minter, Ralph R; Rabbitts, Terence H TH
Publication Date: 2019-06-13

Variant appearance in text: KRAS: S17N
PubMed Link: 31197133
Variant Present in the following documents:
  • Main text
  • 41467_2019_Article_10419.pdf
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: KRAS: S17N
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



K-Ras G-domain binding with signaling lipid phosphatidylinositol (4,5)-phosphate (PIP2): membrane association, protein orientation, and function.

The Journal Of Biological Chemistry
Cao, Shufen S; Chung, Stacey S; Kim, SoonJeung S; Li, Zhenlu Z; Manor, Danny D; Buck, Matthias M
Publication Date: 2019-04-26

Variant appearance in text: K-Ras4B: S17N
PubMed Link: 30792310
Variant Present in the following documents:
  • Main text
View BVdb publication page



Failure to detect functional transfer of active K-Ras protein from extracellular vesicles into recipient cells in culture.

Plos One
Luhtala, Natalie N; Hunter, Tony T
Publication Date: 2018

Variant appearance in text: KRAS: S17N
PubMed Link: 30192821
Variant Present in the following documents:
  • pone.0203290.pdf
View BVdb publication page



BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions.

Elife
Bery, Nicolas N; Cruz-Migoni, Abimael A; Bataille, Carole Jr CJ; Quevedo, Camilo E CE; Tulmin, Hanna H; Miller, Ami A; Russell, Angela A; Phillips, Simon Ev SE; Carr, Stephen B SB; Rabbitts, Terence H TH
Publication Date: 2018-07-10

Variant appearance in text: KRAS: S17N
PubMed Link: 29989546
Variant Present in the following documents:
  • Main text
  • elife-37122.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: KRAS: S17N
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 1
View BVdb publication page



Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia.

Leukemia
Rothenberg-Thurley, Maja M; Amler, Susanne S; Goerlich, Dennis D; Köhnke, Thomas T; Konstandin, Nikola P NP; Schneider, Stephanie S; Sauerland, Maria C MC; Herold, Tobias T; Hubmann, Max M; Ksienzyk, Bianka B; Zellmeier, Evelyn E; Bohlander, Stefan K SK; Subklewe, Marion M; Faldum, Andreas A; Hiddemann, Wolfgang W; Braess, Jan J; Spiekermann, Karsten K; Metzeler, Klaus H KH
Publication Date: 2018-07

Variant appearance in text: KRAS: 50G>A
PubMed Link: 29472724
Variant Present in the following documents:
  • 41375_2018_34_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Comparative Nucleotide-Dependent Interactome Analysis Reveals Shared and Differential Properties of KRas4a and KRas4b.

Acs Central Science
Zhang, Xiaoyu X; Cao, Ji J; Miller, Seth P SP; Jing, Hui H; Lin, Hening H
Publication Date: 2018-01-24

Variant appearance in text: KRAS: S17N
PubMed Link: 29392178
Variant Present in the following documents:
  • Main text
  • oc7b00440.pdf
View BVdb publication page



RAF inhibitors promote RAS-RAF interaction by allosterically disrupting RAF autoinhibition.

Nature Communications
Jin, Ting T; Lavoie, Hugo H; Sahmi, Malha M; David, Maud M; Hilt, Christine C; Hammell, Amy A; Therrien, Marc M
Publication Date: 2017-10-31

Variant appearance in text: KRAS: S17N
PubMed Link: 29084939
Variant Present in the following documents:
  • Main text
  • 41467_2017_Article_1274.pdf
  • 41467_2017_1274_MOESM1_ESM.pdf
View BVdb publication page



Plasma membrane phosphatidylinositol 4-phosphate and 4,5-bisphosphate determine the distribution and function of K-Ras4B but not H-Ras proteins.

The Journal Of Biological Chemistry
Gulyás, Gergő G; Radvánszki, Glória G; Matuska, Rita R; Balla, András A; Hunyady, László L; Balla, Tamas T; Várnai, Péter P
Publication Date: 2017-11-17

Variant appearance in text: K-Ras4B: S17N
PubMed Link: 28939768
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic evidence that β-arrestins are dispensable for the initiation of β2-adrenergic receptor signaling to ERK.

Science Signaling
O'Hayre, Morgan M; Eichel, Kelsie K; Avino, Silvia S; Zhao, Xuefeng X; Steffen, Dana J DJ; Feng, Xiaodong X; Kawakami, Kouki K; Aoki, Junken J; Messer, Karen K; Sunahara, Roger R; Inoue, Asuka A; von Zastrow, Mark M; Gutkind, J Silvio JS
Publication Date: 2017-06-20

Variant appearance in text: KRAS: S17N
PubMed Link: 28634209
Variant Present in the following documents:
  • Main text
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: KRAS: S17N
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page



OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination.

Embo Molecular Medicine
Baietti, Maria Francesca MF; Simicek, Michal M; Abbasi Asbagh, Layka L; Radaelli, Enrico E; Lievens, Sam S; Crowther, Jonathan J; Steklov, Mikhail M; Aushev, Vasily N VN; Martínez García, David D; Tavernier, Jan J; Sablina, Anna A AA
Publication Date: 2016-03-01

Variant appearance in text: KRAS: S17N
PubMed Link: 26881969
Variant Present in the following documents:
  • Main text
View BVdb publication page



Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma.

Cancer Biology & Therapy
Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS
Publication Date: 2016

Variant appearance in text: KRAS: 50G>A
PubMed Link: 26785607
Variant Present in the following documents:
  • kcbt-17-03-1139235.pdf
View BVdb publication page



Genetic heterogeneity of actionable genes between primary and metastatic tumor in lung adenocarcinoma.

Bmc Cancer
Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Kim, Arum A; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS
Publication Date: 2016-01-18

Variant appearance in text: KRAS: 50G>A
PubMed Link: 26782967
Variant Present in the following documents:
  • 12885_2016_2049_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Amplicon sequencing of colorectal cancer: variant calling in frozen and formalin-fixed samples.

Plos One
Betge, Johannes J; Kerr, Grainne G; Miersch, Thilo T; Leible, Svenja S; Erdmann, Gerrit G; Galata, Christian L CL; Zhan, Tianzuo T; Gaiser, Timo T; Post, Stefan S; Ebert, Matthias P MP; Horisberger, Karoline K; Boutros, Michael M
Publication Date: 2015

Variant appearance in text: KRAS: S17N
PubMed Link: 26010451
Variant Present in the following documents:
  • pone.0127146.s014.xlsx, sheet 3
View BVdb publication page



Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology
Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B
Publication Date: 2014-10-28

Variant appearance in text: KRAS: S17N
PubMed Link: 25348012
Variant Present in the following documents:
  • 13059_2014_484_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin.

Genome Medicine
Alakus, Hakan H; Babicky, Michele L ML; Ghosh, Pradipta P; Yost, Shawn S; Jepsen, Kristen K; Dai, Yang Y; Arias, Angelo A; Samuels, Michael L ML; Mose, Evangeline S ES; Schwab, Richard B RB; Peterson, Michael R MR; Lowy, Andrew M AM; Frazer, Kelly A KA; Harismendy, Olivier O
Publication Date: 2014

Variant appearance in text: KRAS: S17N
PubMed Link: 24944587
Variant Present in the following documents:
  • gm559-S3.xls, sheet 12
View BVdb publication page



Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma.

Science Signaling
Zhang, Weiying W; Nandakumar, Nivedita N; Shi, Yuhao Y; Manzano, Mark M; Smith, Alias A; Graham, Garrett G; Gupta, Swati S; Vietsch, Eveline E EE; Laughlin, Sean Z SZ; Wadhwa, Mandheer M; Chetram, Mahandranauth M; Joshi, Mrinmayi M; Wang, Fen F; Kallakury, Bhaskar B; Toretsky, Jeffrey J; Wellstein, Anton A; Yi, Chunling C
Publication Date: 2014-05-06

Variant appearance in text: KRAS: S17N
PubMed Link: 24803537
Variant Present in the following documents:
  • Main text
View BVdb publication page



K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.

Nature
Ostrem, Jonathan M JM; Peters, Ulf U; Sos, Martin L ML; Wells, James A JA; Shokat, Kevan M KM
Publication Date: 2013-11-28

Variant appearance in text: KRAS: S17N
PubMed Link: 24256730
Variant Present in the following documents:
  • Main text
View BVdb publication page



Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization.

Nature Chemical Biology
Lavoie, Hugo H; Thevakumaran, Neroshan N; Gavory, Gwenaëlle G; Li, John J JJ; Padeganeh, Abbas A; Guiral, Sébastien S; Duchaine, Jean J; Mao, Daniel Y L DY; Bouvier, Michel M; Sicheri, Frank F; Therrien, Marc M
Publication Date: 2013-07

Variant appearance in text: KRAS: S17N
PubMed Link: 23685672
Variant Present in the following documents:
  • Main text
View BVdb publication page



Real-time single-molecule co-immunoprecipitation analyses reveal cancer-specific Ras signalling dynamics.

Nature Communications
Lee, Hong-Won HW; Kyung, Taeyoon T; Yoo, Janghyun J; Kim, Tackhoon T; Chung, Chaeuk C; Ryu, Ji Young JY; Lee, Hanki H; Park, Kihyun K; Lee, Sangkyu S; Jones, Walton D WD; Lim, Dae-Sik DS; Hyeon, Changbong C; Heo, Won Do WD; Yoon, Tae-Young TY
Publication Date: 2013

Variant appearance in text: KRAS: S17N
PubMed Link: 23422673
Variant Present in the following documents:
  • ncomms2507.pdf
View BVdb publication page



Mutant and wild-type Ras: co-conspirators in cancer.

Cancer Discovery
Hayes, Tikvah K TK; Der, Channing J CJ
Publication Date: 2013-01

Variant appearance in text: KRAS: S17N
PubMed Link: 23319767
Variant Present in the following documents:
  • Main text
View BVdb publication page



Regulation of voltage-dependent calcium channels by RGK proteins.

Biochimica Et Biophysica Acta
Yang, Tingting T; Colecraft, Henry M HM
Publication Date: 2013-07

Variant appearance in text: K-Ras4B: S17N
PubMed Link: 23063948
Variant Present in the following documents:
  • Main text
View BVdb publication page



Ras history: The saga continues.

Small Gtpases
Cox, Adrienne D AD; Der, Channing J CJ
Publication Date: 2010-07

Variant appearance in text: K-Ras4B: S17N
PubMed Link: 21686117
Variant Present in the following documents:
  • Main text
View BVdb publication page



Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors.

Science Signaling
Sasaki, Atsuo T AT; Carracedo, Arkaitz A; Locasale, Jason W JW; Anastasiou, Dimitrios D; Takeuchi, Koh K; Kahoud, Emily Rose ER; Haviv, Sasson S; Asara, John M JM; Pandolfi, Pier Paolo PP; Cantley, Lewis C LC
Publication Date: 2011-03-08

Variant appearance in text: K-Ras4B: S17N
PubMed Link: 21386094
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutations in the c-Kit gene disrupt mitogen-activated protein kinase signaling during tumor development in adenoid cystic carcinoma of the salivary glands.

Neoplasia (New York, N.Y.)
Tetsu, Osamu O; Phuchareon, Janyaporn J; Chou, Annie A; Cox, Darren P DP; Eisele, David W DW; Jordan, Richard C K RC
Publication Date: 2010-09

Variant appearance in text: KRAS: S17N
PubMed Link: 20824047
Variant Present in the following documents:
  • Main text
View BVdb publication page



Activated Ras induces cytoplasmic vacuolation and non-apoptotic death in glioblastoma cells via novel effector pathways.

Cellular Signalling
Kaul, Aparna A; Overmeyer, Jean H JH; Maltese, William A WA
Publication Date: 2007-05

Variant appearance in text: K-Ras4B: S17N
PubMed Link: 17210246
Variant Present in the following documents:
  • Main text
View BVdb publication page



Expression of Rem2, an RGK family small GTPase, reduces N-type calcium current without affecting channel surface density.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience
Chen, Huanmian H; Puhl, Henry L HL; Niu, Shui-Lin SL; Mitchell, Drake C DC; Ikeda, Stephen R SR
Publication Date: 2005-10-19

Variant appearance in text: K-Ras4B: S17N
PubMed Link: 16237180
Variant Present in the following documents:
  • Main text
View BVdb publication page



Reversible intracellular translocation of KRas but not HRas in hippocampal neurons regulated by Ca2+/calmodulin.

The Journal Of Cell Biology
Fivaz, Marc M; Meyer, Tobias T
Publication Date: 2005-08-01

Variant appearance in text: KRAS: S17N
PubMed Link: 16043511
Variant Present in the following documents:
  • 200409157.pdf
View BVdb publication page



Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells.

Molecular Biology Of The Cell
Jiang, Xuejun X; Sorkin, Alexander A
Publication Date: 2002-05

Variant appearance in text: K-Ras4B: Ser17Asn
PubMed Link: 12006650
Variant Present in the following documents:
  • Main text
View BVdb publication page