Publications:

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Mutually exclusive genetic interactions and gene essentiality shape the genomic landscape of primary melanoma.

The Journal Of Pathology

Birkeälv, Sofia S; Harland, Mark M; Matsuyama, Larissa Satiko Alcantara Sekimoto LSAS; Rashid, Mamun M; Mehta, Ishan I; Laye, Jonathan P JP; Haase, Kerstin K; Mell, Tracey T; Iyer, Vivek V; Robles-Espinoza, Carla Daniela CD; McDermott, Ultan U; van Loo, Peter P; Kuijjer, Marieke L ML; Possik, Patricia A PA; Maria Engler, Silvya Stuchi SS; Bishop, D Timothy DT; Newton-Bishop, Julia J; Adams, David J DJ

Publication Date: 2022-10-11

Variant appearance in text: ERBB2: 922G>A; V308M

PubMed Link: 36219477

Variant Present in the following documents:

• PATH-259-56-s004.xlsx, sheet 2

View BVdb publication page

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Integrated longitudinal analysis of adult grade 4 diffuse gliomas with long-term relapse interval revealed upregulation of TGF-β signaling in recurrent tumors.

Neuro-Oncology

Kashani, Elham E; Schnidrig, Désirée D; Hashemi Gheinani, Ali A; Ninck, Martina Selina MS; Zens, Philipp P; Maragkou, Theoni T; Baumgartner, Ulrich U; Schucht, Philippe P; Rätsch, Gunnar G; Rubin, Mark A MA; Berezowska, Sabina S; Ng, Charlotte K Y CKY; Vassella, Erik E; ,

Publication Date: 2022-09-17

Variant appearance in text: ERBB2: 922G>A; Val308Met

PubMed Link: 36124685

Variant Present in the following documents:

• noac220_suppl_supplementary_table_s3.xlsx, sheet 1

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: ERBB2: 922G>A; Val308Met; rs776515406

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.

Cancer Medicine

Liu, Binliang B; Yi, Zongbi Z; Guan, Yanfang Y; Ouyang, Quchang Q; Li, Chunxiao C; Guan, Xiuwen X; Lv, Dan D; Li, Lixi L; Zhai, Jingtong J; Qian, Haili H; Xu, Binghe B; Ma, Fei F; Zeng, Yixin Y

Publication Date: 2022-07

Variant appearance in text: ERBB2: 922G>A; V308M

PubMed Link: 35393784

Variant Present in the following documents:

• CAM4-11-2767-s001.xlsx, sheet 1

View BVdb publication page

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A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.

Genome Research

Chen, Siwei S; Liu, Yuan Y; Zhang, Yingying Y; Wierbowski, Shayne D SD; Lipkin, Steven M SM; Wei, Xiaomu X; Yu, Haiyuan H

Publication Date: 2022-01

Variant appearance in text: ERBB2: V308M

PubMed Link: 34963661

Variant Present in the following documents:

• supp_gr.275437.121_Supplementary_Table_1.xlsx, sheet 3

View BVdb publication page

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Calibration-free NGS quantitation of mutations below 0.01% VAF.

Nature Communications

Dai, Peng P; Wu, Lucia Ruojia LR; Chen, Sherry Xi SX; Wang, Michael Xiangjiang MX; Cheng, Lauren Yuxuan LY; Zhang, Jinny Xuemeng JX; Hao, Pengying P; Yao, Weijie W; Zarka, Jabra J; Issa, Ghayas C GC; Kwong, Lawrence L; Zhang, David Yu DY

Publication Date: 2021-10-21

Variant appearance in text: ERBB2: 922G>A; V308M

PubMed Link: 34675197

Variant Present in the following documents:

• 41467_2021_26308_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer.

Npj Breast Cancer

Yi, Zongbi Z; Rong, Guohua G; Guan, Yanfang Y; Li, Jin J; Chang, Lianpeng L; Li, Hui H; Liu, Binliang B; Wang, Wenna W; Guan, Xiuwen X; Ouyang, Quchang Q; Li, Lixi L; Zhai, Jingtong J; Li, Chunxiao C; Li, Lifeng L; Xia, Xuefeng X; Yang, Ling L; Qian, Haili H; Yi, Xin X; Xu, Binghe B; Ma, Fei F

Publication Date: 2020

Variant appearance in text: ERBB2: 922G>A; V308M

PubMed Link: 33145402

Variant Present in the following documents:

• 41523_2020_201_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Prospective Clinical Validation of the InVisionFirst-Lung Circulating Tumor DNA Assay for Molecular Profiling of Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer.

Jco Precision Oncology

Pritchett, Michael A MA; Camidge, D Ross DR; Patel, Manu M; Khatri, Jamil J; Boniol, Steven S; Friedman, Elke K EK; Khomani, Abderrahim A; Dalia, Samir S; Baker-Neblett, Katherine K; Plagnol, Vincent V; Howarth, Karen D KD; Jones, Gregory R GR; Rosenfeld, Nitzan N; Morris, Clive D CD; Govindan, Ramaswamy R

Publication Date: 2019

Variant appearance in text: ERBB2: V308M

PubMed Link: 32914040

Variant Present in the following documents:

• PO.18.00299.pdf

View BVdb publication page

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Mutational landscape and characteristics of ERBB2 in non-small cell lung cancer.

Thoracic Cancer

Wei, Xue-Wu XW; Gao, Xin X; Zhang, Xu-Chao XC; Yang, Jin-Ji JJ; Chen, Zhi-Hong ZH; Wu, Yi-Long YL; Zhou, Qing Q

Publication Date: 2020-06

Variant appearance in text: ERBB2: V308M

PubMed Link: 32291971

Variant Present in the following documents:

• Main text
• TCA-11-1512.pdf

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: ERBB2: V308M

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

View BVdb publication page

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: ERBB2: V308M

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 3
• pone.0196434.s001.xlsx, sheet 2
• pone.0196434.s001.xlsx, sheet 1

View BVdb publication page

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Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.

Cancer Cell

Hellmann, Matthew D MD; Nathanson, Tavi T; Rizvi, Hira H; Creelan, Benjamin C BC; Sanchez-Vega, Francisco F; Ahuja, Arun A; Ni, Ai A; Novik, Jacki B JB; Mangarin, Levi M B LMB; Abu-Akeel, Mohsen M; Liu, Cailian C; Sauter, Jennifer L JL; Rekhtman, Natasha N; Chang, Eliza E; Callahan, Margaret K MK; Chaft, Jamie E JE; Voss, Martin H MH; Tenet, Megan M; Li, Xue-Mei XM; Covello, Kelly K; Renninger, Andrea A; Vitazka, Patrik P; Geese, William J WJ; Borghaei, Hossein H; Rudin, Charles M CM; Antonia, Scott J SJ; Swanton, Charles C; Hammerbacher, Jeff J; Merghoub, Taha T; McGranahan, Nicholas N; Snyder, Alexandra A; Wolchok, Jedd D JD

Publication Date: 2018-05-14

Variant appearance in text: ERBB2: V308M

PubMed Link: 29657128

Variant Present in the following documents:

• mmc3.xlsx, sheet 3

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Systematic Functional Annotation of Somatic Mutations in Cancer.

Cancer Cell

Ng, Patrick Kwok-Shing PK; Li, Jun J; Jeong, Kang Jin KJ; Shao, Shan S; Chen, Hu H; Tsang, Yiu Huen YH; Sengupta, Sohini S; Wang, Zixing Z; Bhavana, Venkata Hemanjani VH; Tran, Richard R; Soewito, Stephanie S; Minussi, Darlan Conterno DC; Moreno, Daniela D; Kong, Kathleen K; Dogruluk, Turgut T; Lu, Hengyu H; Gao, Jianjiong J; Tokheim, Collin C; Zhou, Daniel Cui DC; Johnson, Amber M AM; Zeng, Jia J; Ip, Carman Ka Man CKM; Ju, Zhenlin Z; Wester, Matthew M; Yu, Shuangxing S; Li, Yongsheng Y; Vellano, Christopher P CP; Schultz, Nikolaus N; Karchin, Rachel R; Ding, Li L; Lu, Yiling Y; Cheung, Lydia Wai Ting LWT; Chen, Ken K; Shaw, Kenna R KR; Meric-Bernstam, Funda F; Scott, Kenneth L KL; Yi, Song S; Sahni, Nidhi N; Liang, Han H; Mills, Gordon B GB

Publication Date: 2018-03-12

Variant appearance in text: ERBB2: V308M

PubMed Link: 29533785

Variant Present in the following documents:

• Main text

View BVdb publication page

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Multiregion ultra-deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer.

Molecular Oncology

Suzuki, Yuka Y; Ng, Sarah Boonhsi SB; Chua, Clarinda C; Leow, Wei Qiang WQ; Chng, Jermain J; Liu, Shi Yang SY; Ramnarayanan, Kalpana K; Gan, Anna A; Ho, Dan Liang DL; Ten, Rachel R; Su, Yan Y; Lezhava, Alexandar A; Lai, Jiunn Herng JH; Koh, Dennis D; Lim, Kiat Hon KH; Tan, Patrick P; Rozen, Steven G SG; Tan, Iain Beehuat IB

Publication Date: 2017-02

Variant appearance in text: ERBB2: V308M

PubMed Link: 28145097

Variant Present in the following documents:

• MOL2-11-124-s010.xlsx, sheet 1

View BVdb publication page

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Functional annotation of rare gene aberration drivers of pancreatic cancer.

Nature Communications

Tsang, Yiu Huen YH; Dogruluk, Turgut T; Tedeschi, Philip M PM; Wardwell-Ozgo, Joanna J; Lu, Hengyu H; Espitia, Maribel M; Nair, Nikitha N; Minelli, Rosalba R; Chong, Zechen Z; Chen, Fengju F; Chang, Qing Edward QE; Dennison, Jennifer B JB; Dogruluk, Armel A; Li, Min M; Ying, Haoqiang H; Bertino, Joseph R JR; Gingras, Marie-Claude MC; Ittmann, Michael M; Kerrigan, John J; Chen, Ken K; Creighton, Chad J CJ; Eterovic, Karina K; Mills, Gordon B GB; Scott, Kenneth L KL

Publication Date: 2016-01-25

Variant appearance in text: ERBB2: V308M

PubMed Link: 26806015

Variant Present in the following documents:

• ncomms10500-s2.xls, sheet 1

View BVdb publication page

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: ERBB2: V308M

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Somatic mutations identify a subgroup of aplastic anemia patients who progress to myelodysplastic syndrome.

Blood

Kulasekararaj, Austin G AG; Jiang, Jie J; Smith, Alexander E AE; Mohamedali, Azim M AM; Mian, Syed S; Gandhi, Shreyans S; Gaken, Joop J; Czepulkowski, Barbara B; Marsh, Judith C W JC; Mufti, Ghulam J GJ

Publication Date: 2014-10-23

Variant appearance in text: ERBB2: V308M

PubMed Link: 25139356

Variant Present in the following documents:

• Main text

View BVdb publication page

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