Publications:

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Sustained Improvement in the Management of Patients with Non-Small-Cell Lung Cancer (NSCLC) Harboring ALK Translocation: Where Are We Running?

Current Oncology (Toronto, Ont.)

Spitaleri, Gianluca G; Trillo Aliaga, Pamela P; Attili, Ilaria I; Del Signore, Ester E; Corvaja, Carla C; Corti, Chiara C; Crimini, Edoardo E; Passaro, Antonio A; de Marinis, Filippo F

Publication Date: 2023-05-16

Variant appearance in text: ALK: S1206F

PubMed Link: 37232842

Variant Present in the following documents:

• Main text
• curroncol-30-00384.pdf

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EML4-ALK biology and drug resistance in Non-Small Cell Lung Cancer: a new phase of discoveries.

Molecular Oncology

Elshatlawy, Mariam M; Sampson, Josephina J; Clarke, Katy K; Bayliss, Richard R

Publication Date: 2023-05-07

Variant appearance in text: ALK: S1206F

PubMed Link: 37149843

Variant Present in the following documents:

• Main text
• MOL2-17-950.pdf

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Primary resistance to first- and second-generation ALK inhibitors in a non-small cell lung cancer patient with coexisting ALK rearrangement and an ALK F1174L-cis-S1189C de novo mutation: A case report.

Frontiers In Pharmacology

Zhao, Jiuzhou J; Li, Xiang X; Fan, Ruizhe R; Qin, Yaping Y; Wang, Zhizhong Z; Wang, Bo B; Li, Shaomei S; Fan, Jianfeng J; Wu, Xinxin X; Liu, Hongxia H; Guan, Yuping Y; Liang, Yinfeng Y; Zhang, Xiao X; Guo, Yongjun Y

Publication Date: 2022

Variant appearance in text: ALK: S1206F

PubMed Link: 36506539

Variant Present in the following documents:

• Main text
• fphar-13-1060460.pdf

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Multiple Genetic Alterations as Resistance Mechanism during Second-Line Lorlatinib for Advanced ALK-Rearranged Lung Adenocarcinoma: A Case Report.

Diagnostics (Basel, Switzerland)

Catino, Annamaria A; Lacalamita, Rosanna R; De Summa, Simona S; Pesola, Francesco F; Tommasi, Stefania S; Galetta, Domenico D

Publication Date: 2022-03-11

Variant appearance in text: ALK: 3617C>T; S1206F

PubMed Link: 35328235

Variant Present in the following documents:

• Main text
• diagnostics-12-00682.pdf

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A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.

Genome Research

Chen, Siwei S; Liu, Yuan Y; Zhang, Yingying Y; Wierbowski, Shayne D SD; Lipkin, Steven M SM; Wei, Xiaomu X; Yu, Haiyuan H

Publication Date: 2022-01

Variant appearance in text: ALK: S1206F

PubMed Link: 34963661

Variant Present in the following documents:

• supp_gr.275437.121_Supplementary_Table_1.xlsx, sheet 3

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New Advances in Liquid Biopsy Technologies for Anaplastic Lymphoma Kinase (ALK)-Positive Cancer.

Cancers

Villa, Matteo M; Sharma, Geeta G GG; Manfroni, Chiara C; Cortinovis, Diego D; Mologni, Luca L

Publication Date: 2021-10-14

Variant appearance in text: ALK: S1206F

PubMed Link: 34680298

Variant Present in the following documents:

• Main text
• cancers-13-05149.pdf

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A Novel Sequentially Evolved EML4-ALK Variant 3 G1202R/S1206Y Double Mutation In Cis Confers Resistance to Lorlatinib: A Brief Report and Literature Review.

Jto Clinical And Research Reports

Zhu, Viola W VW; Nagasaka, Misako M; Madison, Russell R; Schrock, Alexa B AB; Cui, Jean J; Ou, Sai-Hong Ignatius SI

Publication Date: 2021-01

Variant appearance in text: ALK: S1206F

PubMed Link: 34589977

Variant Present in the following documents:

• Main text
• main.pdf

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Clinical Relevance of an Amplicon-Based Liquid Biopsy for Detecting ALK and ROS1 Fusion and Resistance Mutations in Patients With Non-Small-Cell Lung Cancer.

Jco Precision Oncology

Mezquita, Laura L; Swalduz, Aurélie A; Jovelet, Cécile C; Ortiz-Cuaran, Sandra S; Howarth, Karen K; Planchard, David D; Avrillon, Virginie V; Recondo, Gonzalo G; Marteau, Solène S; Benitez, Jose Carlos JC; De Kievit, Frank F; Plagnol, Vincent V; Lacroix, Ludovic L; Odier, Luc L; Rouleau, Etienne E; Fournel, Pierre P; Caramella, Caroline C; Tissot, Claire C; Adam, Julien J; Woodhouse, Samuel S; Nicotra, Claudio C; Auclin, Edouard E; Remon, Jordi J; Morris, Clive C; Green, Emma E; Massard, Christophe C; Pérol, Maurice M; Friboulet, Luc L; Besse, Benjamin B; Saintigny, Pierre P

Publication Date: 2020

Variant appearance in text: ALK: S1206F

PubMed Link: 32923908

Variant Present in the following documents:

• Main text

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Diverse Resistance Mechanisms to the Third-Generation ALK Inhibitor Lorlatinib in ALK-Rearranged Lung Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Recondo, Gonzalo G; Mezquita, Laura L; Facchinetti, Francesco F; Planchard, David D; Gazzah, Anas A; Bigot, Ludovic L; Rizvi, Ahsan Z AZ; Frias, Rosa L RL; Thiery, Jean Paul JP; Scoazec, Jean-Yves JY; Sourisseau, Tony T; Howarth, Karen K; Deas, Olivier O; Samofalova, Dariia D; Galissant, Justine J; Tesson, Pauline P; Braye, Floriane F; Naltet, Charles C; Lavaud, Pernelle P; Mahjoubi, Linda L; Abou Lovergne, Aurélie A; Vassal, Gilles G; Bahleda, Rastilav R; Hollebecque, Antoine A; Nicotra, Claudio C; Ngo-Camus, Maud M; Michiels, Stefan S; Lacroix, Ludovic L; Richon, Catherine C; Auger, Nathalie N; De Baere, Thierry T; Tselikas, Lambros L; Solary, Eric E; Angevin, Eric E; Eggermont, Alexander M AM; Andre, Fabrice F; Massard, Christophe C; Olaussen, Ken A KA; Soria, Jean-Charles JC; Besse, Benjamin B; Friboulet, Luc L

Publication Date: 2020-01-01

Variant appearance in text: ALK: S1206F

PubMed Link: 31585938

Variant Present in the following documents:

• Main text

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Monitoring Therapeutic Response and Resistance: Analysis of Circulating Tumor DNA in Patients With ALK+ Lung Cancer.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer

Horn, Leora L; Whisenant, Jennifer G JG; Wakelee, Heather H; Reckamp, Karen L KL; Qiao, Huan H; Leal, Ticiana A TA; Du, Liping L; Hernandez, Jennifer J; Huang, Vincent V; Blumenschein, George R GR; Waqar, Saiama N SN; Patel, Sandip P SP; Nieva, Jorge J; Oxnard, Geoffrey R GR; Sanborn, Rachel E RE; Shaffer, Tristan T; Garg, Kavita K; Holzhausen, Allison A; Harrow, Kimberly K; Liang, Chris C; Lim, Lee P LP; Li, Mark M; Lovly, Christine M CM

Publication Date: 2019-11

Variant appearance in text: ALK: S1206F

PubMed Link: 31446141

Variant Present in the following documents:

• Main text

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Profile of alectinib for the treatment of ALK-positive non-small cell lung cancer (NSCLC): patient selection and perspectives.

Oncotargets And Therapy

Karachaliou, Niki N; Fernandez Bruno, Manuel M; Bracht, Jillian Wilhelmina Paulina JWP; Rosell, Rafael R

Publication Date: 2019

Variant appearance in text: ALK: S1206F

PubMed Link: 31354290

Variant Present in the following documents:

• Main text
• ott-12-4567.pdf

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The role of brigatinib in crizotinib-resistant non-small cell lung cancer.

Cancer Management And Research

Mezquita, Laura L; Planchard, David D

Publication Date: 2018

Variant appearance in text: ALK: S1206F

PubMed Link: 29403310

Variant Present in the following documents:

• Main text

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What is the optimal first-line treatment for advanced anaplastic lymphoma kinase-rearranged non-small cell lung cancer?

Journal Of Thoracic Disease

Sekine, Ikuo I

Publication Date: 2017-05

Variant appearance in text: ALK: S1206F

PubMed Link: 28616306

Variant Present in the following documents:

• Main text

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The activity, safety, and evolving role of brigatinib in patients with ALK-rearranged non-small cell lung cancers.

Oncotargets And Therapy

Sabari, Joshua K JK; Santini, Fernando C FC; Schram, Alison M AM; Bergagnini, Isabella I; Chen, Ruqin R; Mrad, Chebli C; Lai, W Victoria WV; Arbour, Kathryn C KC; Drilon, Alexander A

Publication Date: 2017

Variant appearance in text: ALK: S1206F

PubMed Link: 28435288

Variant Present in the following documents:

• Main text
• ott-10-1983.pdf

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De novo ALK kinase domain mutations are uncommon in kinase inhibitor-naïve ALK rearranged lung cancers.

Lung Cancer (Amsterdam, Netherlands)

Lucena-Araujo, Antonio R AR; Moran, Jason P JP; VanderLaan, Paul A PA; Dias-Santagata, Dora D; Folch, Erik E; Majid, Adnan A; Kent, Michael S MS; Gangadharan, Sidharta P SP; Rangachari, Deepa D; Huberman, Mark S MS; Kobayashi, Susumu S SS; Costa, Daniel B DB

Publication Date: 2016-09

Variant appearance in text: ALK: S1206F

PubMed Link: 27565908

Variant Present in the following documents:

• Main text

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VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research.

Nucleic Acids Research

Lai, Zhongwu Z; Markovets, Aleksandra A; Ahdesmaki, Miika M; Chapman, Brad B; Hofmann, Oliver O; McEwen, Robert R; Johnson, Justin J; Dougherty, Brian B; Barrett, J Carl JC; Dry, Jonathan R JR

Publication Date: 2016-06-20

Variant appearance in text: ALK: 3617C>T

PubMed Link: 27060149

Variant Present in the following documents:

• supp_gkw227_nar-03544-met-k-2015-File003.xls, sheet 2

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