Publications:

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Targeting dual oncogenic machineries driven by TAL1 and PI3K-AKT pathways in Tcell acute lymphoblastic leukemia.

Haematologica

Lim, Fang Qi FQ; Chan, Allison Si-Yu AS; Yokomori, Rui R; Huang, Xiao Zi XZ; Theardy, Madelaine Skolastika MS; Yeoh, Allen Eng Juh AEJ; Tan, Shi Hao SH; Sanda, Takaomi T

Publication Date: 2022-09-08

Variant appearance in text: PI3K: Y641F

PubMed Link: 36073513

Variant Present in the following documents:

• 2022_280761_LIM_TABLES_SUPPL.xlsx, sheet 5

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Author Correction: Integrative molecular and clinical profiling of acral melanoma links focal amplification of 22q11.21 to metastasis.

Nature Communications

Farshidfar, Farshad F; Rhrissorrakrai, Kahn K; Levovitz, Chaya C; Peng, Cong C; Knight, James J; Bacchiocchi, Antonella A; Su, Juan J; Yin, Mingzhu M; Sznol, Mario M; Ariyan, Stephan S; Clune, James J; Olino, Kelly K; Parida, Laxmi L; Nikolaus, Joerg J; Zhang, Meiling M; Zhao, Shuang S; Wang, Yan Y; Huang, Gang G; Wan, Miaojian M; Li, Xianan X; Cao, Jian J; Yan, Qin Q; Chen, Xiang X; Newman, Aaron M AM; Halaban, Ruth R

Publication Date: 2022-05-10

Variant appearance in text: PIK3CA: Y641F

PubMed Link: 35538087

Variant Present in the following documents:

• 41467_2022_30446_MOESM1_ESM.xlsx, sheet 2

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KLF5 inhibition overcomes oxaliplatin resistance in patient-derived colorectal cancer organoids by restoring apoptotic response.

Cell Death & Disease

Shen, Xiaohui X; Zhang, Yuchen Y; Xu, Zhuoqing Z; Gao, Han H; Feng, Wenqing W; Li, Wenchang W; Miao, Yiming Y; Xu, Zifeng Z; Zong, Yaping Y; Zhao, Jingkun J; Lu, Aiguo A

Publication Date: 2022-04-05

Variant appearance in text: PI3K: Y641F

PubMed Link: 35379798

Variant Present in the following documents:

• 41419_2022_4773_MOESM9_ESM.xlsx, sheet 1

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Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research

Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL

Publication Date: 2022-05

Variant appearance in text: PI3K: Y641F

PubMed Link: 35229492

Variant Present in the following documents:

• PCMR-35-369-s003.xlsx, sheet 12

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Integrative molecular and clinical profiling of acral melanoma links focal amplification of 22q11.21 to metastasis.

Nature Communications

Farshidfar, Farshad F; Rhrissorrakrai, Kahn K; Levovitz, Chaya C; Peng, Cong C; Knight, James J; Bacchiocchi, Antonella A; Su, Juan J; Yin, Mingzhu M; Sznol, Mario M; Ariyan, Stephan S; Clune, James J; Olino, Kelly K; Parida, Laxmi L; Nikolaus, Joerg J; Zhang, Meiling M; Zhao, Shuang S; Wang, Yan Y; Huang, Gang G; Wan, Miaojian M; Li, Xianan X; Cao, Jian J; Yan, Qin Q; Chen, Xiang X; Newman, Aaron M AM; Halaban, Ruth R

Publication Date: 2022-02-23

Variant appearance in text: PIK3CA: Y641F

PubMed Link: 35197475

Variant Present in the following documents:

• 41467_2022_28566_MOESM5_ESM.xlsx, sheet 2

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Gene Transcription as a Therapeutic Target in Leukemia.

International Journal Of Molecular Sciences

Khamidullina, Alvina I AI; Varlamova, Ekaterina A EA; Hammoud, Nour Alhuda NA; Yastrebova, Margarita A MA; Bruter, Alexandra V AV

Publication Date: 2021-07-08

Variant appearance in text: PI3K: Y641F

PubMed Link: 34298959

Variant Present in the following documents:

• Main text

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The Impact of Epigenetic Modifications in Myeloid Malignancies.

International Journal Of Molecular Sciences

Venney, Deirdra D; Mohd-Sarip, Adone A; Mills, Ken I KI

Publication Date: 2021-05-09

Variant appearance in text: PI3K: Y641F

PubMed Link: 34065087

Variant Present in the following documents:

• Main text

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Higher Mutation Burden in High Proliferation Compartments of Heterogeneous Melanoma Tumors.

International Journal Of Molecular Sciences

Grzywa, Tomasz M TM; Koppolu, Agnieszka A AA; Paskal, Wiktor W; Klicka, Klaudia K; Rydzanicz, Małgorzata M; Wejman, Jarosław J; Płoski, Rafał R; Włodarski, Paweł K PK

Publication Date: 2021-04-09

Variant appearance in text: PIK3CA: 1922A>T; Tyr641Phe

PubMed Link: 33918692

Variant Present in the following documents:

• Main text

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Biomarkers and novel therapeutic approaches for diffuse large B-cell lymphoma in the era of precision medicine.

Oncotarget

Lodhi, Niraj N; Tun, Moe M; Nagpal, Poonam P; Inamdar, Arati A AA; Ayoub, Nehad M NM; Siyam, Noor N; Oton-Gonzalez, Lucia L; Gerona, Angela A; Morris, Dainelle D; Sandhu, Rana R; Suh, Kwangsun Stephen KS

Publication Date: 2020-11-03

Variant appearance in text: PI3K: Y641F

PubMed Link: 33216822

Variant Present in the following documents:

• Main text
• oncotarget-11-4045.pdf

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EZH2 abnormalities in lymphoid malignancies: underlying mechanisms and therapeutic implications.

Journal Of Hematology & Oncology

Li, Boheng B; Chng, Wee-Joo WJ

Publication Date: 2019-11-21

Variant appearance in text: PI3K: Y641F

PubMed Link: 31752930

Variant Present in the following documents:

• Main text
• 13045_2019_Article_814.pdf

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EZH2 as a therapeutic target for multiple myeloma and other haematological malignancies.

Biomarker Research

Tremblay-LeMay, Rosemarie R; Rastgoo, Nasrin N; Pourabdollah, Maryam M; Chang, Hong H

Publication Date: 2018

Variant appearance in text: PI3K: Y641F

PubMed Link: 30555699

Variant Present in the following documents:

• Main text
• 40364_2018_Article_148.pdf

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Mechanisms of resistance to EZH2 inhibitors in diffuse large B-cell lymphomas.

Blood

Bisserier, Malik M; Wajapeyee, Narendra N

Publication Date: 2018-05-10

Variant appearance in text: PI3K: Y641F

PubMed Link: 29572378

Variant Present in the following documents:

• Main text

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New developments in the pathology of malignant lymphoma. A review of the literature published from September-August 2017.

Journal Of Hematopathology

van Krieken, J H JH

Publication Date: 2017-12

Variant appearance in text: PI3K: Y641F

PubMed Link: 29225711

Variant Present in the following documents:

• Main text

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Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets.

Leukemia

Karube, K K; Enjuanes, A A; Dlouhy, I I; Jares, P P; Martin-Garcia, D D; Nadeu, F F; Ordóñez, G R GR; Rovira, J J; Clot, G G; Royo, C C; Navarro, A A; Gonzalez-Farre, B B; Vaghefi, A A; Castellano, G G; Rubio-Perez, C C; Tamborero, D D; Briones, J J; Salar, A A; Sancho, J M JM; Mercadal, S S; Gonzalez-Barca, E E; Escoda, L L; Miyoshi, H H; Ohshima, K K; Miyawaki, K K; Kato, K K; Akashi, K K; Mozos, A A; Colomo, L L; Alcoceba, M M; Valera, A A; Carrió, A A; Costa, D D; Lopez-Bigas, N N; Schmitz, R R; Staudt, L M LM; Salaverria, I I; López-Guillermo, A A; Campo, E E

Publication Date: 2018-03

Variant appearance in text: PIK3CA: Y641F

PubMed Link: 28804123

Variant Present in the following documents:

• leu2017251x2.xlsx, sheet 13

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Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc

Harms, Paul W PW; Collie, Angela M B AM; Hovelson, Daniel H DH; Cani, Andi K AK; Verhaegen, Monique E ME; Patel, Rajiv M RM; Fullen, Douglas R DR; Omata, Kei K; Dlugosz, Andrzej A AA; Tomlins, Scott A SA; Billings, Steven D SD

Publication Date: 2016-03

Variant appearance in text: PIK3CA: Y641F

PubMed Link: 26743471

Variant Present in the following documents:

• Main text

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Novel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: a comprehensive review.

Molecular Cancer

Camicia, Rosalba R; Winkler, Hans C HC; Hassa, Paul O PO

Publication Date: 2015-12-11

Variant appearance in text: PI3K: Y641F

PubMed Link: 26654227

Variant Present in the following documents:

• Main text
• 12943_2015_Article_474.pdf

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Massive transcriptional perturbation in subgroups of diffuse large B-cell lymphomas.

Plos One

Rosolowski, Maciej M; Läuter, Jürgen J; Abramov, Dmitriy D; Drexler, Hans G HG; Hummel, Michael M; Klapper, Wolfram W; Macleod, Roderick A F RA; Pellissery, Shoji S; Horn, Friedemann F; Siebert, Reiner R; Loeffler, Markus M

Publication Date: 2013

Variant appearance in text: PI3K: Y641F

PubMed Link: 24223701

Variant Present in the following documents:

• pone.0076287.pdf

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Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research

Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C

Publication Date: 2011-09-01

Variant appearance in text: PIK3CA: Y641F

PubMed Link: 21727090

Variant Present in the following documents:

• supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1

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