Publications:

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Assessing variants of uncertain significance implicated in hearing loss using a comprehensive deafness proteome.

Human Genetics

Tollefson, Mallory R MR; Gogal, Rose A RA; Weaver, A Monique AM; Schaefer, Amanda M AM; Marini, Robert J RJ; Azaiez, Hela H; Kolbe, Diana L DL; Wang, Donghong D; Weaver, Amy E AE; Casavant, Thomas L TL; Braun, Terry A TA; Smith, Richard J H RJH; Schnieders, Michael J MJ

Publication Date: 2023-04-22

Variant appearance in text: FGFR3: 1663G>A; Val555Met

PubMed Link: 37086329

Variant Present in the following documents:

• 439_2023_2559_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors.

Communications Chemistry

Qu, Lingzhi L; Chen, Xiaojuan X; Wei, Hudie H; Guo, Ming M; Dai, Shuyan S; Jiang, Longying L; Li, Jun J; Yue, Sitong S; Chen, Zhuchu Z; Chen, Yongheng Y

Publication Date: 2022-01-11

Variant appearance in text: FGFR3: V555M

PubMed Link: 36697561

Variant Present in the following documents:

• Main text
• 42004_2021_Article_623.pdf
• 42004_2021_623_MOESM2_ESM.pdf
• 42004_2021_623_MOESM1_ESM.pdf

View BVdb publication page

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Clinical Evidence and Selecting Patients for Treatment with Erdafitinib in Advanced Urothelial Carcinoma.

Oncotargets And Therapy

Sayegh, Nicolas N; Tripathi, Nishita N; Agarwal, Neeraj N; Swami, Umang U

Publication Date: 2022

Variant appearance in text: FGFR3: V555M

PubMed Link: 36186154

Variant Present in the following documents:

• Main text
• ott-15-1047.pdf

View BVdb publication page

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Protein tyrosine kinase inhibitor resistance in malignant tumors: molecular mechanisms and future perspective.

Signal Transduction And Targeted Therapy

Yang, Yang Y; Li, Shuo S; Wang, Yujiao Y; Zhao, Yi Y; Li, Qiu Q

Publication Date: 2022-09-17

Variant appearance in text: FGFR3: V555M

PubMed Link: 36115852

Variant Present in the following documents:

• Main text
• 41392_2022_Article_1168.pdf

View BVdb publication page

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Brain-restricted mTOR inhibition with binary pharmacology.

Nature

Zhang, Ziyang Z; Fan, Qiwen Q; Luo, Xujun X; Lou, Kevin K; Weiss, William A WA; Shokat, Kevan M KM

Publication Date: 2022-09

Variant appearance in text: FGFR3: V555M

PubMed Link: 36104566

Variant Present in the following documents:

• 41586_2022_5213_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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A lymphatic-absorbed multi-targeted kinase inhibitor for myelofibrosis therapy.

Nature Communications

Ross, Brian D BD; Jang, Youngsoon Y; Welton, Amanda A; Bonham, Christopher A CA; Palagama, Dilrukshika S W DSW; Heist, Kevin K; Boppisetti, Jagadish J; Imaduwage, Kasun P KP; Robison, Tanner T; King, Leah R LR; Zhang, Edward Z EZ; Amirfazli, Cyrus C; Luker, Kathryn E KE; Lee, Winston Y WY; Luker, Gary D GD; Chenevert, Thomas L TL; Van Dort, Marcian E ME

Publication Date: 2022-08-17

Variant appearance in text: FGFR3: V555M

PubMed Link: 35977945

Variant Present in the following documents:

• 41467_2022_32486_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Mechanisms of acquired resistance to fibroblast growth factor receptor targeted therapy.

Cancer Drug Resistance (Alhambra, Calif.)

Lau, David K DK; Jenkins, Laura L; Weickhardt, Andrew A

Publication Date: 2019

Variant appearance in text: FGFR3: V555M

PubMed Link: 35582593

Variant Present in the following documents:

• cdr-2-568.pdf

View BVdb publication page

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Molecularly Targeted Therapy towards Genetic Alterations in Advanced Bladder Cancer.

Cancers

Thomas, Jonathan J; Sonpavde, Guru G

Publication Date: 2022-04-01

Variant appearance in text: FGFR3: V555M

PubMed Link: 35406567

Variant Present in the following documents:

• Main text
• cancers-14-01795.pdf

View BVdb publication page

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Fibroblast Growth Factor Receptor 1-4 Genetic Aberrations as Clinically Relevant Biomarkers in Squamous Cell Lung Cancer.

Frontiers In Oncology

Moes-Sosnowska, Joanna J; Chorostowska-Wynimko, Joanna J

Publication Date: 2022

Variant appearance in text: FGFR3: V555M

PubMed Link: 35402233

Variant Present in the following documents:

• Main text
• fonc-12-780650.pdf

View BVdb publication page

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Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.

Cancer Medicine

Liu, Binliang B; Yi, Zongbi Z; Guan, Yanfang Y; Ouyang, Quchang Q; Li, Chunxiao C; Guan, Xiuwen X; Lv, Dan D; Li, Lixi L; Zhai, Jingtong J; Qian, Haili H; Xu, Binghe B; Ma, Fei F; Zeng, Yixin Y

Publication Date: 2022-07

Variant appearance in text: FGFR3: 1663G>A; V555M

PubMed Link: 35393784

Variant Present in the following documents:

• CAM4-11-2767-s001.xlsx, sheet 1

View BVdb publication page

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Small molecule LATS kinase inhibitors block the Hippo signaling pathway and promote cell growth under 3D culture conditions.

The Journal Of Biological Chemistry

Aihara, Ayako A; Iwawaki, Takumi T; Abe-Fukasawa, Natsuki N; Otsuka, Keiichiro K; Saruhashi, Koichiro K; Mikashima, Takumi T; Nishino, Taito T

Publication Date: 2022-04

Variant appearance in text: FGFR3: V555M

PubMed Link: 35231442

Variant Present in the following documents:

• mmc1.pdf

View BVdb publication page

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Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research

Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL

Publication Date: 2022-05

Variant appearance in text: FGFR3: V555M

PubMed Link: 35229492

Variant Present in the following documents:

• PCMR-35-369-s003.xlsx, sheet 12

View BVdb publication page

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: FGFR3: Val555Met

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.

Nature Neuroscience

Baxi, Emily G EG; Thompson, Terri T; Li, Jonathan J; Kaye, Julia A JA; Lim, Ryan G RG; Wu, Jie J; Ramamoorthy, Divya D; Lima, Leandro L; Vaibhav, Vineet V; Matlock, Andrea A; Frank, Aaron A; Coyne, Alyssa N AN; Landin, Barry B; Ornelas, Loren L; Mosmiller, Elizabeth E; Thrower, Sara S; Farr, S Michelle SM; Panther, Lindsey L; Gomez, Emilda E; Galvez, Erick E; Perez, Daniel D; Meepe, Imara I; Lei, Susan S; Mandefro, Berhan B; Trost, Hannah H; Pinedo, Louis L; Banuelos, Maria G MG; Liu, Chunyan C; Moran, Ruby R; Garcia, Veronica V; Workman, Michael M; Ho, Richie R; Wyman, Stacia S; Roggenbuck, Jennifer J; Harms, Matthew B MB; Stocksdale, Jennifer J; Miramontes, Ricardo R; Wang, Keona K; Venkatraman, Vidya V; Holewenski, Ronald R; Sundararaman, Niveda N; Pandey, Rakhi R; Manalo, Danica-Mae DM; Donde, Aneesh A; Huynh, Nhan N; Adam, Miriam M; Wassie, Brook T BT; Vertudes, Edward E; Amirani, Naufa N; Raja, Krishna K; Thomas, Reuben R; Hayes, Lindsey L; Lenail, Alex A; Cerezo, Aianna A; Luppino, Sarah S; Farrar, Alanna A; Pothier, Lindsay L; Prina, Carolyn C; Morgan, Todd T; Jamil, Arish A; Heintzman, Sarah S; Jockel-Balsarotti, Jennifer J; Karanja, Elizabeth E; Markway, Jesse J; McCallum, Molly M; Joslin, Ben B; Alibazoglu, Deniz D; Kolb, Stephen S; Ajroud-Driss, Senda S; Baloh, Robert R; Heitzman, Daragh D; Miller, Tim T; Glass, Jonathan D JD; Patel-Murray, Natasha Leanna NL; Yu, Hong H; Sinani, Ervin E; Vigneswaran, Prasha P; Sherman, Alexander V AV; Ahmad, Omar O; Roy, Promit P; Beavers, Jay C JC; Zeiler, Steven S; Krakauer, John W JW; Agurto, Carla C; Cecchi, Guillermo G; Bellard, Mary M; Raghav, Yogindra Y; Sachs, Karen K; Ehrenberger, Tobias T; Bruce, Elizabeth E; Cudkowicz, Merit E ME; Maragakis, Nicholas N; Norel, Raquel R; Van Eyk, Jennifer E JE; Finkbeiner, Steven S; Berry, James J; Sareen, Dhruv D; Thompson, Leslie M LM; Fraenkel, Ernest E; Svendsen, Clive N CN; Rothstein, Jeffrey D JD

Publication Date: 2022-02

Variant appearance in text: FGFR3: V555M

PubMed Link: 35115730

Variant Present in the following documents:

• 41593_2021_1006_MOESM4_ESM.xlsx, sheet 9
• 41593_2021_1006_MOESM4_ESM.xlsx, sheet 8

View BVdb publication page

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FGF/FGFR-Dependent Molecular Mechanisms Underlying Anti-Cancer Drug Resistance.

Cancers

Szymczyk, Jakub J; Sluzalska, Katarzyna Dominika KD; Materla, Izabela I; Opalinski, Lukasz L; Otlewski, Jacek J; Zakrzewska, Malgorzata M

Publication Date: 2021-11-18

Variant appearance in text: FGFR3: V555M

PubMed Link: 34830951

Variant Present in the following documents:

• Main text
• cancers-13-05796.pdf

View BVdb publication page

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Targetable Pathways in Advanced Bladder Cancer: FGFR Signaling.

Cancers

Xiao, Jin-Fen JF; Caliri, Andrew W AW; Duex, Jason E JE; Theodorescu, Dan D

Publication Date: 2021-09-29

Variant appearance in text: FGFR3: V555M

PubMed Link: 34638374

Variant Present in the following documents:

• Main text

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: FGFR3: V555M

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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FGFR Inhibitors in Oncology: Insight on the Management of Toxicities in Clinical Practice.

Cancers

Kommalapati, Anuhya A; Tella, Sri Harsha SH; Borad, Mitesh M; Javle, Milind M; Mahipal, Amit A

Publication Date: 2021-06-13

Variant appearance in text: FGFR3: V555M

PubMed Link: 34199304

Variant Present in the following documents:

• cancers-13-02968.pdf

View BVdb publication page

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Insights of fibroblast growth factor receptor 3 aberrations in pan-cancer and their roles in potential clinical treatment.

Aging

Li, Juanni J; Hu, Kuan K; Huang, Jinzhou J; Zhou, Lei L; Yan, Yuanliang Y; Xu, Zhijie Z

Publication Date: 2021-06-23

Variant appearance in text: FGFR3: V555M

PubMed Link: 34160364

Variant Present in the following documents:

• Main text

View BVdb publication page

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GZD824 overcomes FGFR1-V561F/M mutant resistance in vitro and in vivo.

Cancer Medicine

Jiang, Kaili K; Tang, Xia X; Guo, Jing J; He, Rui R; Chan, Shingpan S; Song, Xiaojuan X; Tu, Zhengchao Z; Wang, Yuting Y; Ren, Xiaomei X; Ding, Ke K; Zhang, Zhang Z

Publication Date: 2021-07

Variant appearance in text: FGFR3: V555M

PubMed Link: 34114373

Variant Present in the following documents:

• Main text
• CAM4-10-4874.pdf

View BVdb publication page

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Evolution of kinase polypharmacology across HSP90 drug discovery.

Cell Chemical Biology

Antolin, Albert A AA; Clarke, Paul A PA; Collins, Ian I; Workman, Paul P; Al-Lazikani, Bissan B

Publication Date: 2021-10-21

Variant appearance in text: FGFR3: V555M

PubMed Link: 34077750

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

View BVdb publication page

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Targeting the Fibroblast Growth Factor Receptor (FGFR) Family in Lung Cancer.

Cells

Pacini, Laura L; Jenks, Andrew D AD; Lima, Nadia Carvalho NC; Huang, Paul H PH

Publication Date: 2021-05-10

Variant appearance in text: FGFR3: V555M

PubMed Link: 34068816

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identifying therapeutic drug targets using bidirectional effect genes.

Nature Communications

Estrada, Karol K; Froelich, Steven S; Wuster, Arthur A; Bauer, Christopher R CR; Sterling, Teague T; Clark, Wyatt T WT; Ru, Yuanbin Y; Trinidad, Marena M; Nguyen, Hong Phuc HP; Luu, Amanda R AR; Wendt, Daniel J DJ; Yogalingam, Gouri G; Yu, Guoying Karen GK; LeBowitz, Jonathan H JH; Cardon, Lon R LR

Publication Date: 2021-04-13

Variant appearance in text: FGFR3: 1663G>A; Val555Met

PubMed Link: 33850126

Variant Present in the following documents:

• 41467_2021_21843_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Targeting FGFR in non-small cell lung cancer: implications from the landscape of clinically actionable aberrations of FGFR kinases.

Cancer Biology & Medicine

Zhou, Zhen Z; Liu, Zichuan Z; Ou, Qiuxiang Q; Wu, Xue X; Wang, Xiaonan X; Shao, Yang Y; Liu, Hongyan H; Yang, Yu Y

Publication Date: 2021-03-12

Variant appearance in text: FGFR3: V555M

PubMed Link: 33710807

Variant Present in the following documents:

• cbm-18-490-s001.pdf

View BVdb publication page

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FGFR-TKI resistance in cancer: current status and perspectives.

Journal Of Hematology & Oncology

Yue, Sitong S; Li, Yukun Y; Chen, Xiaojuan X; Wang, Juan J; Li, Meixiang M; Chen, Yongheng Y; Wu, Daichao D

Publication Date: 2021-02-10

Variant appearance in text: FGFR3: V555M

PubMed Link: 33568192

Variant Present in the following documents:

• Main text
• 13045_2021_Article_1040.pdf

View BVdb publication page

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Discovery of Aminopyrazole Derivatives as Potent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR2 and 3.

Acs Medicinal Chemistry Letters

Brawn, Ryan A RA; Cook, Andrew A; Omoto, Kiyoyuki K; Ke, Jiyuan J; Karr, Craig C; Colombo, Federico F; Virrankoski, Milena M; Prajapati, Sudeep S; Reynolds, Dominic D; Bolduc, David M DM; Nguyen, Tuong-Vi TV; Gee, Patricia P; Borrelli, Deanna D; Caleb, Benjamin B; Yao, Shihua S; Irwin, Sean S; Larsen, Nicholas A NA; Selvaraj, Anand A; Zhao, Xuesong X; Ioannidis, Stephanos S

Publication Date: 2021-01-14

Variant appearance in text: FGFR3: V555M

PubMed Link: 33488969

Variant Present in the following documents:

• Main text

View BVdb publication page

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Novel Tyrosine Kinase Targets in Urothelial Carcinoma.

International Journal Of Molecular Sciences

Torres-Jiménez, Javier J; Albarrán-Fernández, Víctor V; Pozas, Javier J; Román-Gil, María San MS; Esteban-Villarrubia, Jorge J; Carrato, Alfredo A; Rosero, Adriana A; Grande, Enrique E; Alonso-Gordoa, Teresa T; Molina-Cerrillo, Javier J

Publication Date: 2021-01-13

Variant appearance in text: FGFR3: V555M

PubMed Link: 33451055

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: FGFR3: 1663G>A; V555M

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Fibroblast growth factor receptors in cancer: genetic alterations, diagnostics, therapeutic targets and mechanisms of resistance.

British Journal Of Cancer

Krook, Melanie A MA; Reeser, Julie W JW; Ernst, Gabrielle G; Barker, Hannah H; Wilberding, Max M; Li, Gary G; Chen, Hui-Zi HZ; Roychowdhury, Sameek S

Publication Date: 2021-03

Variant appearance in text: FGFR3: V555M

PubMed Link: 33268819

Variant Present in the following documents:

• Main text
• 41416_2020_Article_1157.pdf

View BVdb publication page

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Tyrosine Kinase Receptors in Oncology.

International Journal Of Molecular Sciences

Esteban-Villarrubia, Jorge J; Soto-Castillo, Juan José JJ; Pozas, Javier J; San Román-Gil, María M; Orejana-Martín, Inmaculada I; Torres-Jiménez, Javier J; Carrato, Alfredo A; Alonso-Gordoa, Teresa T; Molina-Cerrillo, Javier J

Publication Date: 2020-11-12

Variant appearance in text: FGFR3: V555M

PubMed Link: 33198314

Variant Present in the following documents:

• Main text
• ijms-21-08529.pdf

View BVdb publication page

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Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer.

Npj Breast Cancer

Yi, Zongbi Z; Rong, Guohua G; Guan, Yanfang Y; Li, Jin J; Chang, Lianpeng L; Li, Hui H; Liu, Binliang B; Wang, Wenna W; Guan, Xiuwen X; Ouyang, Quchang Q; Li, Lixi L; Zhai, Jingtong J; Li, Chunxiao C; Li, Lifeng L; Xia, Xuefeng X; Yang, Ling L; Qian, Haili H; Yi, Xin X; Xu, Binghe B; Ma, Fei F

Publication Date: 2020

Variant appearance in text: FGFR3: 1663G>A; V555M

PubMed Link: 33145402

Variant Present in the following documents:

• 41523_2020_201_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Ultradeep targeted sequencing of circulating tumor DNA in plasma of early and advanced breast cancer.

Cancer Science

Chin, Yoon Ming YM; Takahashi, Yoko Y; Chan, Hiu Ting HT; Otaki, Masumi M; Fujishima, Makoto M; Shibayama, Tomoko T; Miki, Yoshio Y; Ueno, Takayuki T; Nakamura, Yusuke Y; Low, Siew-Kee SK

Publication Date: 2021-01

Variant appearance in text: FGFR3: V555M

PubMed Link: 33075187

Variant Present in the following documents:

• CAS-112-454-s002.xlsx, sheet 11
• CAS-112-454-s002.xlsx, sheet 6
• CAS-112-454-s002.xlsx, sheet 9

View BVdb publication page

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Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports

Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA

Publication Date: 2020-09-21

Variant appearance in text: FGFR3: V555M

PubMed Link: 32958805

Variant Present in the following documents:

• 41598_2020_72404_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

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FGF/FGFR signaling in health and disease.

Signal Transduction And Targeted Therapy

Xie, Yangli Y; Su, Nan N; Yang, Jing J; Tan, Qiaoyan Q; Huang, Shuo S; Jin, Min M; Ni, Zhenhong Z; Zhang, Bin B; Zhang, Dali D; Luo, Fengtao F; Chen, Hangang H; Sun, Xianding X; Feng, Jian Q JQ; Qi, Huabing H; Chen, Lin L

Publication Date: 2020-09-02

Variant appearance in text: FGFR3: V555M

PubMed Link: 32879300

Variant Present in the following documents:

• Main text

View BVdb publication page

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Fibroblast Growth Factor Receptor (FGFR) Inhibitors in Urothelial Cancer.

The Oncologist

Garje, Rohan R; An, Josiah J; Obeidat, Mohammad M; Kumar, Kranthi K; Yasin, Hesham A HA; Zakharia, Yousef Y

Publication Date: 2020-11

Variant appearance in text: FGFR3: V555M

PubMed Link: 32790011

Variant Present in the following documents:

• Main text
• ONCO-25-e1711.pdf

View BVdb publication page

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FGF/FGFR signaling pathway involved resistance in various cancer types.

Journal Of Cancer

Zhou, Yangyang Y; Wu, Chengyu C; Lu, Guangrong G; Hu, Zijing Z; Chen, Qiuxiang Q; Du, Xiaojing X

Publication Date: 2020

Variant appearance in text: FGFR3: V555M

PubMed Link: 32127928

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: FGFR3: V555M

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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Efficacy of FGFR Inhibitors and Combination Therapies for Acquired Resistance in FGFR2-Fusion Cholangiocarcinoma.

Molecular Cancer Therapeutics

Krook, Melanie A MA; Lenyo, Alexandria A; Wilberding, Max M; Barker, Hannah H; Dantuono, Mikayla M; Bailey, Kelly M KM; Chen, Hui-Zi HZ; Reeser, Julie W JW; Wing, Michele R MR; Miya, Jharna J; Samorodnitsky, Eric E; Smith, Amy M AM; Dao, Thuy T; Martin, Dorrelyn M DM; Ciombor, Kristen K KK; Hays, John J; Freud, Aharon G AG; Roychowdhury, Sameek S

Publication Date: 2020-03

Variant appearance in text: FGFR3: V555M

PubMed Link: 31911531

Variant Present in the following documents:

• Main text

View BVdb publication page

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Facts and New Hopes on Selective FGFR Inhibitors in Solid Tumors.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Facchinetti, Francesco F; Hollebecque, Antoine A; Bahleda, Rastislav R; Loriot, Yohann Y; Olaussen, Ken A KA; Massard, Christophe C; Friboulet, Luc L

Publication Date: 2020-02-15

Variant appearance in text: FGFR3: V555M

PubMed Link: 31585937

Variant Present in the following documents:

• Main text

View BVdb publication page

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A Novel FGFR3 Splice Variant Preferentially Expressed in African American Prostate Cancer Drives Aggressive Phenotypes and Docetaxel Resistance.

Molecular Cancer Research : Mcr

Olender, Jacqueline J; Wang, Bi-Dar BD; Ching, Travers T; Garmire, Lana X LX; Garofano, Kaitlin K; Ji, Youngmi Y; Knox, Tessa T; Latham, Patricia P; Nguyen, Kenneth K; Rhim, Johng J; Lee, Norman H NH

Publication Date: 2019-10

Variant appearance in text: FGFR3: V555M

PubMed Link: 31266816

Variant Present in the following documents:

• Main text

View BVdb publication page

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Fibroblast Growth Factor Receptors (FGFRs): Structures and Small Molecule Inhibitors.

Cells

Dai, Shuyan S; Zhou, Zhan Z; Chen, Zhuchu Z; Xu, Guangyu G; Chen, Yongheng Y

Publication Date: 2019-06-18

Variant appearance in text: FGFR3: V555M

PubMed Link: 31216761

Variant Present in the following documents:

• Main text
• cells-08-00614.pdf

View BVdb publication page

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Germline susceptibility variants impact clinical outcome and therapeutic strategies for stage III colorectal cancer.

Scientific Reports

Lin, Peng-Chan PC; Yeh, Yu-Min YM; Wu, Pei-Ying PY; Hsu, Keng-Fu KF; Chang, Jang-Yang JY; Shen, Meng-Ru MR

Publication Date: 2019-03-08

Variant appearance in text: FGFR3: 1663G>A; Val555Met

PubMed Link: 30850667

Variant Present in the following documents:

• 41598_2019_40571_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Ensemble-Based Replica Exchange Alchemical Free Energy Methods: The Effect of Protein Mutations on Inhibitor Binding.

Journal Of Chemical Theory And Computation

Bhati, Agastya P AP; Wan, Shunzhou S; Coveney, Peter V PV

Publication Date: 2019-02-12

Variant appearance in text: FGFR3: V555M

PubMed Link: 30592603

Variant Present in the following documents:

• Main text

View BVdb publication page

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Structure, activation and dysregulation of fibroblast growth factor receptor kinases: perspectives for clinical targeting.

Biochemical Society Transactions

Farrell, Brendan B; Breeze, Alexander L AL

Publication Date: 2018-12-17

Variant appearance in text: FGFR3: V555M

PubMed Link: 30545934

Variant Present in the following documents:

• Main text
• BST-46-1753.pdf

View BVdb publication page

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Whole-Exome Sequencing Identifies Causative Mutations in Families with Congenital Anomalies of the Kidney and Urinary Tract.

Journal Of The American Society Of Nephrology : Jasn

van der Ven, Amelie T AT; Connaughton, Dervla M DM; Ityel, Hadas H; Mann, Nina N; Nakayama, Makiko M; Chen, Jing J; Vivante, Asaf A; Hwang, Daw-Yang DY; Schulz, Julian J; Braun, Daniela A DA; Schmidt, Johanna Magdalena JM; Schapiro, David D; Schneider, Ronen R; Warejko, Jillian K JK; Daga, Ankana A; Majmundar, Amar J AJ; Tan, Weizhen W; Jobst-Schwan, Tilman T; Hermle, Tobias T; Widmeier, Eugen E; Ashraf, Shazia S; Amar, Ali A; Hoogstraaten, Charlotte A CA; Hugo, Hannah H; Kitzler, Thomas M TM; Kause, Franziska F; Kolvenbach, Caroline M CM; Dai, Rufeng R; Spaneas, Leslie L; Amann, Kassaundra K; Stein, Deborah R DR; Baum, Michelle A MA; Somers, Michael J G MJG; Rodig, Nancy M NM; Ferguson, Michael A MA; Traum, Avram Z AZ; Daouk, Ghaleb H GH; Bogdanović, Radovan R; Stajić, Natasa N; Soliman, Neveen A NA; Kari, Jameela A JA; El Desoky, Sherif S; Fathy, Hanan M HM; Milosevic, Danko D; Al-Saffar, Muna M; Awad, Hazem S HS; Eid, Loai A LA; Selvin, Aravind A; Senguttuvan, Prabha P; Sanna-Cherchi, Simone S; Rehm, Heidi L HL; MacArthur, Daniel G DG; Lek, Monkol M; Laricchia, Kristen M KM; Wilson, Michael W MW; Mane, Shrikant M SM; Lifton, Richard P RP; Lee, Richard S RS; Bauer, Stuart B SB; Lu, Weining W; Reutter, Heiko M HM; Tasic, Velibor V; Shril, Shirlee S; Hildebrandt, Friedhelm F

Publication Date: 2018-09

Variant appearance in text: FGFR3: 1663G>A; Val555Met

PubMed Link: 30143558

Variant Present in the following documents:

• Main text

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Integrative omics analyses broaden treatment targets in human cancer.

Genome Medicine

Sengupta, Sohini S; Sun, Sam Q SQ; Huang, Kuan-Lin KL; Oh, Clara C; Bailey, Matthew H MH; Varghese, Rajees R; Wyczalkowski, Matthew A MA; Ning, Jie J; Tripathi, Piyush P; McMichael, Joshua F JF; Johnson, Kimberly J KJ; Kandoth, Cyriac C; Welch, John J; Ma, Cynthia C; Wendl, Michael C MC; Payne, Samuel H SH; Fenyö, David D; Townsend, Reid R RR; Dipersio, John F JF; Chen, Feng F; Ding, Li L

Publication Date: 2018-07-27

Variant appearance in text: FGFR3: V555M

PubMed Link: 30053901

Variant Present in the following documents:

• 13073_2018_564_MOESM2_ESM.xlsx, sheet 3

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Disease Variants of FGFR3 Reveal Molecular Basis for the Recognition and Additional Roles for Cdc37 in Hsp90 Chaperone System.

Structure (London, England : 1993)

Bunney, Tom D TD; Inglis, Alison J AJ; Sanfelice, Domenico D; Farrell, Brendan B; Kerr, Christopher J CJ; Thompson, Gary S GS; Masson, Glenn R GR; Thiyagarajan, Nethaji N; Svergun, Dmitri I DI; Williams, Roger L RL; Breeze, Alexander L AL; Katan, Matilda M

Publication Date: 2018-03-06

Variant appearance in text: FGFR3: V555M

PubMed Link: 29478821

Variant Present in the following documents:

• mmc3.pdf
• mmc1.pdf

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Akt Activation Mediates Acquired Resistance to Fibroblast Growth Factor Receptor Inhibitor BGJ398.

Molecular Cancer Therapeutics

Datta, Jharna J; Damodaran, Senthilkumar S; Parks, Hannah H; Ocrainiciuc, Cristina C; Miya, Jharna J; Yu, Lianbo L; Gardner, Elijah P EP; Samorodnitsky, Eric E; Wing, Michele R MR; Bhatt, Darshna D; Hays, John J; Reeser, Julie W JW; Roychowdhury, Sameek S

Publication Date: 2017-04

Variant appearance in text: FGFR3: V555M

PubMed Link: 28255027

Variant Present in the following documents:

• Main text

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