BRAF c.1797A>G ;(p.T599=)

Variant ID: 7-140453138-T-C

NM_004333.4(BRAF):c.1797A>G;(p.T599=)

This variant was identified in 12 publications

View GRCh38 version.




Publications:


Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy.

Jama Neurology
Khoshkhoo, Sattar S; Wang, Yilan Y; Chahine, Yasmine Y; Erson-Omay, E Zeynep EZ; Robert, Stephanie M SM; Kiziltug, Emre E; Damisah, Eyiyemisi C EC; Nelson-Williams, Carol C; Zhu, Guangya G; Kong, Wenna W; Huang, August Yue AY; Stronge, Edward E; Phillips, H Westley HW; Chhouk, Brian H BH; Bizzotto, Sara S; Chen, Ming Hui MH; Adikari, Thiuni N TN; Ye, Zimeng Z; Witkowski, Tom T; Lai, Dulcie D; Lee, Nadine N; Lokan, Julie J; Scheffer, Ingrid E IE; Berkovic, Samuel F SF; Haider, Shozeb S; Hildebrand, Michael S MS; Yang, Edward E; Gunel, Murat M; Lifton, Richard P RP; Richardson, R Mark RM; Blümcke, Ingmar I; Alexandrescu, Sanda S; Huttner, Anita A; Heinzen, Erin L EL; Zhu, Jidong J; Poduri, Annapurna A; DeLanerolle, Nihal N; Spencer, Dennis D DD; Lee, Eunjung Alice EA; Walsh, Christopher A CA; Kahle, Kristopher T KT
Publication Date: 2023-05-01

Variant appearance in text: BRAF: 1797A>G
PubMed Link: 37126322
Variant Present in the following documents:
  • Main text
  • jamaneurol-e230473.pdf
View BVdb publication page



Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications
Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G
Publication Date: 2023-03-11

Variant appearance in text: BRAF: T599T
PubMed Link: 36906579
Variant Present in the following documents:
  • 41467_2023_36922_MOESM4_ESM.xls, sheet 2
View BVdb publication page



Genomic landscape of the immunogenicity regulation in skin melanomas with diverse tumor mutation burden.

Frontiers In Immunology
Georgoulias, George G; Zaravinos, Apostolos A
Publication Date: 2022

Variant appearance in text: BRAF: T599T
PubMed Link: 36389735
Variant Present in the following documents:
  • Table_7.xlsx, sheet 8
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: BRAF: 1797A>G; T599T
PubMed Link: 35936718
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



Association between BRAF mutant classification and the efficacy of pemetrexed-based chemotherapy in Chinese advanced non-small cell lung cancer patients: a multicenter retrospective study.

Translational Cancer Research
Lei, Lei L; Wang, Wen-Xian WX; Zhu, You-Cai YC; Pu, Xing-Xiang XX; Fang, Yong Y; Wang, Hong H; Zhuang, Wu W; Zhang, Yin-Bin YB; Wang, Li-Ping LP; Xu, Chun-Wei CW; Fang, Mei-Yu MY
Publication Date: 2020-10

Variant appearance in text: BRAF: T599T
PubMed Link: 35117215
Variant Present in the following documents:
  • Main text
  • tcr-09-10-6039.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: N/A
PubMed Link: 29698444
Variant Present in the following documents:
View BVdb publication page



RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells.

Scientific Reports
Qutob, Nouar N; Masuho, Ikuo I; Alon, Michal M; Emmanuel, Rafi R; Cohen, Isadora I; Di Pizio, Antonella A; Madore, Jason J; Elkahloun, Abdel A; Ziv, Tamar T; Levy, Ronen R; Gartner, Jared J JJ; Hill, Victoria K VK; Lin, Jimmy C JC; Hevroni, Yael Y; Greenberg, Polina P; Brodezki, Alexandra A; Rosenberg, Steven A SA; Kosloff, Mickey M; Hayward, Nicholas K NK; Admon, Arie A; Niv, Masha Y MY; Scolyer, Richard A RA; Martemyanov, Kirill A KA; Samuels, Yardena Y
Publication Date: 2018-01-12

Variant appearance in text: BRAF: T599T
PubMed Link: 29330521
Variant Present in the following documents:
  • 41598_2017_18851_MOESM2_ESM.xlsx, sheet 1
  • 41598_2017_18851_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications
Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ
Publication Date: 2017-08-04

Variant appearance in text: BRAF: 1797A>G; T599T
PubMed Link: 28775315
Variant Present in the following documents:
  • 41467_2017_289_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



The detection and significance of EGFR and BRAF in cell-free DNA of peripheral blood in NSCLC.

Oncotarget
Yang, Yang Y; Shen, Xiaoyan X; Li, Rutian R; Shen, Jie J; Zhang, Hang H; Yu, Lixia L; Liu, Baorui B; Wang, Lifeng L
Publication Date: 2017-07-25

Variant appearance in text: BRAF: T599T
PubMed Link: 28572536
Variant Present in the following documents:
  • Main text
  • oncotarget-08-49773.pdf
View BVdb publication page



Precision medicine driven by cancer systems biology.

Cancer Metastasis Reviews
Filipp, Fabian V FV
Publication Date: 2017-03

Variant appearance in text: BRAF: T599T
PubMed Link: 28265786
Variant Present in the following documents:
  • Main text
  • 10555_2017_Article_9662.pdf
View BVdb publication page



Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas.

Nature Genetics
Brastianos, Priscilla K PK; Taylor-Weiner, Amaro A; Manley, Peter E PE; Jones, Robert T RT; Dias-Santagata, Dora D; Thorner, Aaron R AR; Lawrence, Michael S MS; Rodriguez, Fausto J FJ; Bernardo, Lindsay A LA; Schubert, Laura L; Sunkavalli, Ashwini A; Shillingford, Nick N; Calicchio, Monica L ML; Lidov, Hart G W HG; Taha, Hala H; Martinez-Lage, Maria M; Santi, Mariarita M; Storm, Phillip B PB; Lee, John Y K JY; Palmer, James N JN; Adappa, Nithin D ND; Scott, R Michael RM; Dunn, Ian F IF; Laws, Edward R ER; Stewart, Chip C; Ligon, Keith L KL; Hoang, Mai P MP; Van Hummelen, Paul P; Hahn, William C WC; Louis, David N DN; Resnick, Adam C AC; Kieran, Mark W MW; Getz, Gad G; Santagata, Sandro S
Publication Date: 2014-02

Variant appearance in text: BRAF: T599T
PubMed Link: 24413733
Variant Present in the following documents:
  • NIHMS547859-supplement-1.xlsx, sheet 3
View BVdb publication page



Automated universal BRAF state detection within the activation segment in skin metastases by pyrosequencing-based assay U-BRAF(V600).

Plos One
Skorokhod, Alexander A; Helmbold, Peter P; Brors, Benedikt B; Schirmacher, Peter P; Enk, Alexander A; Penzel, Roland R
Publication Date: 2013

Variant appearance in text: BRAF: T599T
PubMed Link: 23555633
Variant Present in the following documents:
  • Main text
  • pone.0059221.s002.pdf
  • pone.0059221.pdf
View BVdb publication page