Publications:

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An integrated model for predicting KRAS dependency.

Plos Computational Biology

Tsai, Yihsuan S YS; Chareddy, Yogitha S YS; Price, Brandon A BA; Parker, Joel S JS; Pecot, Chad V CV

Publication Date: 2023-05-04

Variant appearance in text: BRAF: L597V

PubMed Link: 37141389

Variant Present in the following documents:

• Main text
• pcbi.1011095.pdf

View BVdb publication page

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Pathogenic genomic alterations in Chinese pancreatic cancer patients and their therapeutical implications.

Cancer Medicine

Zhao, Zhiming Z; Li, Xiaomo X; Wang, Fei F; Xu, Yong Y; Liu, Si S; Han, Quanli Q; Yang, Zhiying Z; Huang, Weiwei W; Yin, Zhuzeng Z; Liu, Qu Q; Tan, Haidong H; Ma, Tonghui T; Si, Shuang S; Huang, Jia J; Yuan, Hongling H; Li, Wei W; Liu, Rong R

Publication Date: 2023-03-31

Variant appearance in text: BRAF: L597V

PubMed Link: 36999792

Variant Present in the following documents:

• CAM4-12-11672.pdf

View BVdb publication page

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Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications

Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G

Publication Date: 2023-03-11

Variant appearance in text: BRAF: L597V

PubMed Link: 36906579

Variant Present in the following documents:

• 41467_2023_36922_MOESM4_ESM.xls, sheet 2

View BVdb publication page

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Association of BRAF Variants With Disease Characteristics, Prognosis, and Targeted Therapy Response in Intrahepatic Cholangiocarcinoma.

Jama Network Open

Xin, Hao-Yang HY; Sun, Rong-Qi RQ; Zou, Ji-Xue JX; Wang, Peng-Cheng PC; Wang, Jia-Yin JY; Ye, Yu-Hang YH; Liu, Kai-Xuan KX; Hu, Zhi-Qiang ZQ; Zhou, Zheng-Jun ZJ; Fan, Jia J; Zhou, Jian J; Zhou, Shao-Lai SL

Publication Date: 2023-03-01

Variant appearance in text: BRAF: L597V

PubMed Link: 36867406

Variant Present in the following documents:

• jamanetwopen-e231476-s001.pdf

View BVdb publication page

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Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery

Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI

Publication Date: 2023-03-02

Variant appearance in text: BRAF: L597V

PubMed Link: 36862804

Variant Present in the following documents:

• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 5

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: BRAF: 1789C>G; Leu597Val

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Tumor-Type Agnostic, Targeted Therapies: BRAF Inhibitors Join the Group.

Acta Medica Academica

Vranic, Semir S; Basu, Gargi D GD; Hall, David W DW; Gatalica, Zoran Z

Publication Date: 2022-12-30

Variant appearance in text: BRAF: L597V

PubMed Link: 36799315

Variant Present in the following documents:

• AMA-51-217.pdf

View BVdb publication page

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Significance of logistic regression scoring model based on natural killer cell-mediated cytotoxic pathway in the diagnosis of colon cancer.

Frontiers In Immunology

Ye, Zhen Z; Zhang, Huanhuan H; Liang, Jianwei J; Yi, Shuying S; Zhan, Xianquan X

Publication Date: 2023

Variant appearance in text: BRAF: L597V; rs121913369

PubMed Link: 36742322

Variant Present in the following documents:

• Table_8.xlsx, sheet 1

View BVdb publication page

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: BRAF: L597V

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Integrated gene analyses of de novo variants from 46,612 trios with autism and developmental disorders.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Wang, Tianyun T; Kim, Chang N CN; Bakken, Trygve E TE; Gillentine, Madelyn A MA; Henning, Barbara B; Mao, Yafei Y; Gilissen, Christian C; , ; Nowakowski, Tomasz J TJ; Eichler, Evan E EE

Publication Date: 2022-11-15

Variant appearance in text: BRAF: 1789C>G; Leu597Val

PubMed Link: 36350923

Variant Present in the following documents:

• pnas.2203491119.sd01.xlsx, sheet 1

View BVdb publication page

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Uterine lavage identifies cancer mutations and increased TP53 somatic mutation burden in individuals with ovarian cancer.

Cancer Research Communications

Ghezelayagh, Talayeh S TS; Kohrn, Brendan F BF; Fredrickson, Jeanne J; Manhardt, Enna E; Radke, Marc R MR; Katz, Ronit R; Gray, Heidi J HJ; Urban, Renata R RR; Pennington, Kathryn P KP; Liao, John B JB; Doll, Kemi M KM; Simons, Elise J EJ; Burzawa, Jennifer K JK; Goff, Barbara A BA; Speiser, Paul P; Swisher, Elizabeth M EM; Norquist, Barbara M BM; Risques, Rosa Ana RA

Publication Date: 2022-10

Variant appearance in text: BRAF: 1789C>G; L597V

PubMed Link: 36311816

Variant Present in the following documents:

• crc-22-0314-s02.xlsx, sheet 6

View BVdb publication page

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Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes.

Nature Genetics

Zhou, Xueya X; Feliciano, Pamela P; Shu, Chang C; Wang, Tianyun T; Astrovskaya, Irina I; Hall, Jacob B JB; Obiajulu, Joseph U JU; Wright, Jessica R JR; Murali, Shwetha C SC; Xu, Simon Xuming SX; Brueggeman, Leo L; Thomas, Taylor R TR; Marchenko, Olena O; Fleisch, Christopher C; Barns, Sarah D SD; Snyder, LeeAnne Green LG; Han, Bing B; Chang, Timothy S TS; Turner, Tychele N TN; Harvey, William T WT; Nishida, Andrew A; O'Roak, Brian J BJ; Geschwind, Daniel H DH; , ; Michaelson, Jacob J JJ; Volfovsky, Natalia N; Eichler, Evan E EE; Shen, Yufeng Y; Chung, Wendy K WK

Publication Date: 2022-09

Variant appearance in text: BRAF: 1789C>G; L597V

PubMed Link: 35982159

Variant Present in the following documents:

• 41588_2022_1148_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: BRAF: 1789C>G; L597V

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics

Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS

Publication Date: 2022-08

Variant appearance in text: BRAF: L597V

PubMed Link: 35835912

Variant Present in the following documents:

• 41588_2022_1121_MOESM3_ESM.xlsx, sheet 3

View BVdb publication page

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Clinical Targeted Panel Sequencing Analysis in Clinical Evaluation of Children with Autism Spectrum Disorder in China.

Genes

Hu, Chunchun C; He, Linlin L; Li, Huiping H; Ding, Yanhua Y; Zhang, Kaifeng K; Li, Dongyun D; Zhu, Guoqing G; Wu, Bingbing B; Xu, Xiu X; Xu, Qiong Q

Publication Date: 2022-06-02

Variant appearance in text: BRAF: 1789C>G; L597V

PubMed Link: 35741772

Variant Present in the following documents:

• genes-13-01010.pdf

View BVdb publication page

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Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine

Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R

Publication Date: 2022-05

Variant appearance in text: BRAF: 1789C>G; Leu597Val

PubMed Link: 35244186

Variant Present in the following documents:

• Supplementary_Data2.xlsx, sheet 1
• Supplementary_Data3.xlsx, sheet 1

View BVdb publication page

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: BRAF: Leu597Val

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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The RASopathies: from pathogenetics to therapeutics.

Disease Models & Mechanisms

Hebron, Katie E KE; Hernandez, Edjay Ralph ER; Yohe, Marielle E ME

Publication Date: 2022-02-01

Variant appearance in text: BRAF: L597V

PubMed Link: 35178568

Variant Present in the following documents:

• Main text

View BVdb publication page

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Immune checkpoint inhibitors and driver oncogenes in non-small cell lung cancer.

Translational Cancer Research

Miura, Yosuke Y; Kasahara, Norimitsu N; Sunaga, Noriaki N

Publication Date: 2019-12

Variant appearance in text: BRAF: L597V

PubMed Link: 35117146

Variant Present in the following documents:

• Main text
• tcr-08-S6-S628.pdf

View BVdb publication page

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Molecular characterization of Kita-Kyushu lung cancer antigen (KK-LC-1) expressing carcinomas.

Oncotarget

Hsu, Robert R; Baca, Yasmine Y; Xiu, Joanne J; Wang, Rongfu R; Bodor, J Nicholas JN; Kim, Chul C; Khan, Hina H; Mamdani, Hirva H; Nagasaka, Misako M; Puri, Sonam S; Liu, Stephen V SV; Korn, W Michael WM; Nieva, Jorge J JJ

Publication Date: 2021-12-07

Variant appearance in text: BRAF: L597V

PubMed Link: 34917263

Variant Present in the following documents:

• oncotarget-12-2449-s001.pdf

View BVdb publication page

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Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer.

Nature Cancer

Westcott, Peter M K PMK; Sacks, Nathan J NJ; Schenkel, Jason M JM; Ely, Zackery A ZA; Smith, Olivia O; Hauck, Haley H; Jaeger, Alex M AM; Zhang, Daniel D; Backlund, Coralie M CM; Beytagh, Mary C MC; Patten, J J JJ; Elbashir, Ryan R; Eng, George G; Irvine, Darrell J DJ; Yilmaz, Omer H OH; Jacks, Tyler T

Publication Date: 2021-10

Variant appearance in text: BRAF: 1789C>G; Leu597Val

PubMed Link: 34738089

Variant Present in the following documents:

• NIHMS1725490-supplement-Source_Data_Figure_1.xlsx, sheet 1

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: BRAF: L597V

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Improvement of Neoantigen Identification Through Convolution Neural Network.

Frontiers In Immunology

Hao, Qing Q; Wei, Ping P; Shu, Yang Y; Zhang, Yi-Guan YG; Xu, Heng H; Zhao, Jun-Ning JN

Publication Date: 2021

Variant appearance in text: BRAF: L597V

PubMed Link: 34113354

Variant Present in the following documents:

• Table_1.xlsx, sheet 6

View BVdb publication page

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Comparison of two targeted ultra-deep sequencing technologies for analysis of plasma circulating tumour DNA in endocrine-therapy-resistant breast cancer patients.

Breast Cancer Research And Treatment

Nteliopoulos, Georgios G; Page, Karen K; Hills, Allison A; Howarth, Karen K; Emmett, Warren W; Green, Emma E; Martinson, Luke J LJ; Fernadez-Garcia, Daniel D; Hastings, Robert R; Guttery, David S DS; Kenny, Laura L; Stebbing, Justin J; Cleator, Susan S; Rehman, Farah F; Gleason, Kelly L T KLT; Sanela, Andrijac A; Ion, Charlotte C; Rushton, Amelia J AJ; Rosenfeld, Nitzan N; Coombes, R Charles RC; Shaw, Jacqueline A JA

Publication Date: 2021-07

Variant appearance in text: BRAF: L597V

PubMed Link: 34097174

Variant Present in the following documents:

• 10549_2021_6220_MOESM2_ESM.xlsx, sheet 1
• 10549_2021_6220_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

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Evolution of kinase polypharmacology across HSP90 drug discovery.

Cell Chemical Biology

Antolin, Albert A AA; Clarke, Paul A PA; Collins, Ian I; Workman, Paul P; Al-Lazikani, Bissan B

Publication Date: 2021-10-21

Variant appearance in text: BRAF: L597V

PubMed Link: 34077750

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

View BVdb publication page

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Defining the Criteria for Reflex Testing for BRAF Mutations in Cutaneous Melanoma Patients.

Cancers

Zhou, Sarah S; Sikorski, Daniel D; Xu, Honghao H; Zubarev, Andrei A; Chergui, May M; Lagacé, François F; Miller, Wilson H WH; Redpath, Margaret M; Ghazal, Stephanie S; Butler, Marcus O MO; Petrella, Teresa M TM; Claveau, Joël J; Nessim, Carolyn C; Salopek, Thomas G TG; Gniadecki, Robert R; Litvinov, Ivan V IV

Publication Date: 2021-05-10

Variant appearance in text: BRAF: L597V

PubMed Link: 34068774

Variant Present in the following documents:

• Main text

View BVdb publication page

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Spatially interacting phosphorylation sites and mutations in cancer.

Nature Communications

Huang, Kuan-Lin KL; Scott, Adam D AD; Zhou, Daniel Cui DC; Wang, Liang-Bo LB; Weerasinghe, Amila A; Elmas, Abdulkadir A; Liu, Ruiyang R; Wu, Yige Y; Wendl, Michael C MC; Wyczalkowski, Matthew A MA; Baral, Jessika J; Sengupta, Sohini S; Lai, Chin-Wen CW; Ruggles, Kelly K; Payne, Samuel H SH; Raphael, Benjamin B; Fenyö, David D; Chen, Ken K; Mills, Gordon G; Ding, Li L

Publication Date: 2021-04-19

Variant appearance in text: BRAF: L597V

PubMed Link: 33875650

Variant Present in the following documents:

• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 5
• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: BRAF: 1789C>G; L597V

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Mutant-selective degradation by BRAF-targeting PROTACs.

Nature Communications

Alabi, Shanique S; Jaime-Figueroa, Saul S; Yao, Zhan Z; Gao, Yijun Y; Hines, John J; Samarasinghe, Kusal T G KTG; Vogt, Lea L; Rosen, Neal N; Crews, Craig M CM

Publication Date: 2021-02-10

Variant appearance in text: BRAF: L597V

PubMed Link: 33568647

Variant Present in the following documents:

• Main text
• 41467_2021_Article_21159.pdf

View BVdb publication page

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Assessment of RAS Dependency for BRAF Alterations Using Cancer Genomic Databases.

Jama Network Open

Zhao, Yiqing Y; Yu, Hanzhong H; Ida, Cris M CM; Halling, Kevin C KC; Kipp, Benjamin R BR; Geiersbach, Katherine K; Rumilla, Kandelaria M KM; Gupta, Sounak S; Lin, Ming-Tseh MT; Zheng, Gang G

Publication Date: 2021-01-04

Variant appearance in text: BRAF: L597V

PubMed Link: 33507258

Variant Present in the following documents:

• jamanetwopen-e2035479-s001.pdf

View BVdb publication page

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Comprehensive Characterization of Stage IIIA Non-Small Cell Lung Carcinoma.

Cancer Management And Research

Singh, Neetu N; Mishra, Archana A; Sahu, Dinesh Kumar DK; Jain, Mayank M; Shyam, Hari H; Tripathi, Ratnesh Kumar RK; Shankar, Pratap P; Kumar, Anil A; Alam, Nawazish N; Jaiswal, Riddhi R; Kumar, Shailendra S

Publication Date: 2020

Variant appearance in text: BRAF: 1789C>G; L597V

PubMed Link: 33244273

Variant Present in the following documents:

• Main text

View BVdb publication page

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Molecular and Immune Biomarkers for Cutaneous Melanoma: Current Status and Future Prospects.

Cancers

Pilla, Lorenzo L; Alberti, Andrea A; Di Mauro, Pierluigi P; Gemelli, Maria M; Cogliati, Viola V; Cazzaniga, Marina Elena ME; Bidoli, Paolo P; Maccalli, Cristina C

Publication Date: 2020-11-20

Variant appearance in text: BRAF: L597V

PubMed Link: 33233603

Variant Present in the following documents:

• Main text

View BVdb publication page

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Integrated molecular drivers coordinate biological and clinical states in melanoma.

Nature Genetics

Conway, Jake R JR; Dietlein, Felix F; Taylor-Weiner, Amaro A; AlDubayan, Saud S; Vokes, Natalie N; Keenan, Tanya T; Reardon, Brendan B; He, Meng Xiao MX; Margolis, Claire A CA; Weirather, Jason L JL; Haq, Rizwan R; Schilling, Bastian B; Stephen Hodi, F F; Schadendorf, Dirk D; Liu, David D; Van Allen, Eliezer M EM

Publication Date: 2020-12

Variant appearance in text: rs121913369

PubMed Link: 33230298

Variant Present in the following documents:

• NIHMS1637640-supplement-SuppData1.xlsx, sheet 1

View BVdb publication page

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Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Mayrhofer, Johanna E JE; Enzler, Florian F; Feichtner, Andreas A; Röck, Ruth R; Fleischmann, Jakob J; Raffeiner, Andrea A; Tschaikner, Philipp P; Ogris, Egon E; Huber, Roland G RG; Hartl, Markus M; Schneider, Rainer R; Troppmair, Jakob J; Torres-Quesada, Omar O; Stefan, Eduard E

Publication Date: 2020-12-08

Variant appearance in text: BRAF: L597V

PubMed Link: 33229534

Variant Present in the following documents:

• Main text

View BVdb publication page

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Emerging BRAF Mutations in Cancer Progression and Their Possible Effects on Transcriptional Networks.

Genes

Śmiech, Magdalena M; Leszczyński, Paweł P; Kono, Hidetoshi H; Wardell, Christopher C; Taniguchi, Hiroaki H

Publication Date: 2020-11-12

Variant appearance in text: BRAF: L597V

PubMed Link: 33198372

Variant Present in the following documents:

• Main text
• genes-11-01342.pdf

View BVdb publication page

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Quantitative Structure-Mutation-Activity Relationship Tests (QSMART) model for protein kinase inhibitor response prediction.

Bmc Bioinformatics

Huang, Liang-Chin LC; Yeung, Wayland W; Wang, Ye Y; Cheng, Huimin H; Venkat, Aarya A; Li, Sheng S; Ma, Ping P; Rasheed, Khaled K; Kannan, Natarajan N

Publication Date: 2020-11-12

Variant appearance in text: BRAF: L597V

PubMed Link: 33183223

Variant Present in the following documents:

• Main text

View BVdb publication page

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Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity.

Genome Biology

Lee, Won-Chul WC; Reuben, Alexandre A; Hu, Xin X; McGranahan, Nicholas N; Chen, Runzhe R; Jalali, Ali A; Negrao, Marcelo V MV; Hubert, Shawna M SM; Tang, Chad C; Wu, Chia-Chin CC; Lucas, Anthony San AS; Roh, Whijae W; Suda, Kenichi K; Kim, Jihye J; Tan, Aik-Choon AC; Peng, David H DH; Lu, Wei W; Tang, Ximing X; Chow, Chi-Wan CW; Fujimoto, Junya J; Behrens, Carmen C; Kalhor, Neda N; Fukumura, Kazutaka K; Coyle, Marcus M; Thornton, Rebecca R; Gumbs, Curtis C; Li, Jun J; Wu, Chang-Jiun CJ; Little, Latasha L; Roarty, Emily E; Song, Xingzhi X; Lee, J Jack JJ; Sulman, Erik P EP; Rao, Ganesh G; Swisher, Stephen S; Diao, Lixia L; Wang, Jing J; Heymach, John V JV; Huse, Jason T JT; Scheet, Paul P; Wistuba, Ignacio I II; Gibbons, Don L DL; Futreal, P Andrew PA; Zhang, Jianhua J; Gomez, Daniel D; Zhang, Jianjun J

Publication Date: 2020-11-04

Variant appearance in text: BRAF: L597V

PubMed Link: 33148332

Variant Present in the following documents:

• 13059_2020_2175_MOESM1_ESM.xlsx, sheet 5

View BVdb publication page

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Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports

Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O

Publication Date: 2020-10-13

Variant appearance in text: rs121913369

PubMed Link: 33051506

Variant Present in the following documents:

• 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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KANK1-NTRK3 fusions define a subset of BRAF mutation negative renal metanephric adenomas.

Bmc Medical Genetics

Catic, Aida A; Kurtovic-Kozaric, Amina A; Sophian, Ardis A; Mazur, Lech L; Skenderi, Faruk F; Hes, Ondrej O; Rohan, Stephen S; Rakheja, Dinesh D; Kogan, Jillene J; Pins, Michael R MR

Publication Date: 2020-10-12

Variant appearance in text: BRAF: L597V

PubMed Link: 33046021

Variant Present in the following documents:

• Main text
• 12881_2020_Article_1143.pdf

View BVdb publication page

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Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports

Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA

Publication Date: 2020-09-21

Variant appearance in text: BRAF: L597V

PubMed Link: 32958805

Variant Present in the following documents:

• 41598_2020_72404_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

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BRAF in Lung Cancers: Analysis of Patient Cases Reveals Recurrent BRAF Mutations, Fusions, Kinase Duplications, and Concurrent Alterations.

Jco Precision Oncology

Sheikine, Yuri Y; Pavlick, Dean D; Klempner, Samuel J SJ; Trabucco, Sally E SE; Chung, Jon H JH; Rosenzweig, Mark M; Wang, Kai K; Velcheti, Vamsidhar V; Frampton, Garrett M GM; Peled, Nir N; Murray, Molly M; Chae, Young Kwang YK; Albacker, Lee A LA; Gay, Laurie L; Husain, Hatim H; Suh, James H JH; Millis, Sherri Z SZ; Reddy, Venkataprasanth P VP; Elvin, Julia A JA; Hartmaier, Ryan J RJ; Dowlati, Afshin A; Stephens, Phil P; Ross, Jeffrey S JS; Bivona, Trever G TG; Miller, Vincent A VA; Ganesan, Shridar S; Schrock, Alexa B AB; Ou, Sai-Hong Ignatius SI; Ali, Siraj M SM

Publication Date: 2018

Variant appearance in text: BRAF: L597V

PubMed Link: 32913992

Variant Present in the following documents:

• Main text

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Inhibitors of BRAF dimers using an allosteric site.

Nature Communications

Cotto-Rios, Xiomaris M XM; Agianian, Bogos B; Gitego, Nadege N; Zacharioudakis, Emmanouil E; Giricz, Orsi O; Wu, Yang Y; Zou, Yiyu Y; Verma, Amit A; Poulikakos, Poulikos I PI; Gavathiotis, Evripidis E

Publication Date: 2020-09-01

Variant appearance in text: BRAF: L597V

PubMed Link: 32873792

Variant Present in the following documents:

• Main text

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Construction of a reference material panel for detecting KRAS/NRAS/EGFR/BRAF/MET mutations in plasma ctDNA.

Journal Of Clinical Pathology

Xu, Jun J; Qu, Shoufang S; Sun, Nan N; Zhang, Wenxin W; Zhang, Juanli J; Song, Qingtao Q; Lin, Mufei M; Gao, Wei W; Zheng, Qiaosong Q; Han, Mipeng M; Na, Chenglong C; Xu, Ren R; Chang, Xiaoyan X; Yang, Xuexi X; Huang, Jie J

Publication Date: 2021-05

Variant appearance in text: BRAF: 1789C>G; L597V

PubMed Link: 32817175

Variant Present in the following documents:

• Main text
• jclinpath-2020-206745supp001.pdf
• jclinpath-2020-206745.pdf

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Functional characterization of a PROTAC directed against BRAF mutant V600E.

Nature Chemical Biology

Posternak, Ganna G; Tang, Xiaojing X; Maisonneuve, Pierre P; Jin, Ting T; Lavoie, Hugo H; Daou, Salima S; Orlicky, Stephen S; Goullet de Rugy, Theo T; Caldwell, Lauren L; Chan, Kin K; Aman, Ahmed A; Prakesch, Michael M; Poda, Gennady G; Mader, Pavel P; Wong, Cassandra C; Maier, Stefan S; Kitaygorodsky, Julia J; Larsen, Brett B; Colwill, Karen K; Yin, Zhe Z; Ceccarelli, Derek F DF; Batey, Robert A RA; Taipale, Mikko M; Kurinov, Igor I; Uehling, David D; Wrana, Jeff J; Durocher, Daniel D; Gingras, Anne-Claude AC; Al-Awar, Rima R; Therrien, Marc M; Sicheri, Frank F

Publication Date: 2020-11

Variant appearance in text: BRAF: L597V

PubMed Link: 32778845

Variant Present in the following documents:

• Main text

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Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine

Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y

Publication Date: 2020-08-01

Variant appearance in text: BRAF: 1789C>G; L597V

PubMed Link: 32738923

Variant Present in the following documents:

• 12967_2020_2449_MOESM2_ESM.xlsx, sheet 1
• 12967_2020_2449_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Molecular Basis for Ser/Thr Specificity in PKA Signaling.

Cells

Knape, Matthias J MJ; Wallbott, Maximilian M; Burghardt, Nicole C G NCG; Bertinetti, Daniela D; Hornung, Jan J; Schmidt, Sven H SH; Lorenz, Robin R; Herberg, Friedrich W FW

Publication Date: 2020-06-25

Variant appearance in text: BRAF: L597V

PubMed Link: 32630525

Variant Present in the following documents:

• Main text

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mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports

Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM

Publication Date: 2020-06-23

Variant appearance in text: BRAF: L597V

PubMed Link: 32579932

Variant Present in the following documents:

• mmc5.xlsx, sheet 3

View BVdb publication page

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FAM83G Is a Novel Inducer of Apoptosis.

Molecules (Basel, Switzerland)

Okada, Junichi J; Sunaga, Noriaki N; Yamada, Eijiro E; Saito, Tsugumichi T; Ozawa, Atsushi A; Nakajima, Yasuyo Y; Okada, Kazuya K; Pessin, Jeffrey E JE; Okada, Shuichi S; Yamada, Masanobu M

Publication Date: 2020-06-18

Variant appearance in text: BRAF: L597V

PubMed Link: 32570757

Variant Present in the following documents:

• Main text
• molecules-25-02810.pdf

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Molecular Landscape of BRAF-Mutant NSCLC Reveals an Association Between Clonality and Driver Mutations and Identifies Targetable Non-V600 Driver Mutations.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer

Negrao, Marcelo V MV; Raymond, Victoria M VM; Lanman, Richard B RB; Robichaux, Jacqulyne P JP; He, Junqin J; Nilsson, Monique B MB; Ng, Patrick K S PKS; Amador, Bianca E BE; Roarty, Emily B EB; Nagy, Rebecca J RJ; Banks, Kimberly C KC; Zhu, Viola W VW; Ng, Chun C; Chae, Young Kwang YK; Clarke, Jeffrey M JM; Crawford, Jeffrey A JA; Meric-Bernstam, Funda F; Ignatius Ou, Sai-Hong SH; Gandara, David R DR; Heymach, John V JV; Bivona, Trever G TG; McCoach, Caroline E CE

Publication Date: 2020-10

Variant appearance in text: BRAF: L597V

PubMed Link: 32540409

Variant Present in the following documents:

• Main text

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Tumor Location Is Associated With the Prevalence of Braf And Pik3ca Mutations in Patients with Wild-Type Ras Colorectal Cancer: A Prospective Multi-Center Cohort Study in Japan.

Translational Oncology

Taniguchi, Hiroya H; Uehara, Keisuke K; Nakayama, Goro G; Nakayama, Hiroshi H; Aiba, Toshisada T; Hattori, Norifumi N; Kataoka, Masato M; Nakano, Yasuyuki Y; Kawase, Yoshihisa Y; Okochi, Osamu O; Matsuoka, Hiroshi H; Utsunomiya, Setsuo S; Sakamoto, Eiji E; Mori, Yoshinori Y; Umeda, Shinichi S; Shikano, Toshio T; Komori, Koji K; Tajika, Masahiro M; Kadowaki, Shigenori S; Muro, Kei K; Yatabe, Yasushi Y

Publication Date: 2020-07

Variant appearance in text: BRAF: L597V

PubMed Link: 32428838

Variant Present in the following documents:

• Main text
• main.pdf

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: BRAF: L597V

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 11

View BVdb publication page

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The paradox of cancer genes in non-malignant conditions: implications for precision medicine.

Genome Medicine

Adashek, Jacob J JJ; Kato, Shumei S; Lippman, Scott M SM; Kurzrock, Razelle R

Publication Date: 2020-02-17

Variant appearance in text: BRAF: L597V

PubMed Link: 32066498

Variant Present in the following documents:

• Main text

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Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy.

Cells

Degirmenci, Ufuk U; Wang, Mei M; Hu, Jiancheng J

Publication Date: 2020-01-13

Variant appearance in text: BRAF: L597V

PubMed Link: 31941155

Variant Present in the following documents:

• cells-09-00198.pdf

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Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology

Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M

Publication Date: 2020-01-07

Variant appearance in text: BRAF: 1789C>G; L597V

PubMed Link: 31925297

Variant Present in the following documents:

• 42003_2019_736_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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The impact of RASopathy-associated mutations on CNS development in mice and humans.

Molecular Brain

Kang, Minkyung M; Lee, Yong-Seok YS

Publication Date: 2019-11-21

Variant appearance in text: BRAF: L597V

PubMed Link: 31752929

Variant Present in the following documents:

• Main text

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Clonal selection confers distinct evolutionary trajectories in BRAF-driven cancers.

Nature Communications

Gopal, Priyanka P; Sarihan, Elif Irem EI; Chie, Eui Kyu EK; Kuzmishin, Gwendolyn G; Doken, Semihcan S; Pennell, Nathan A NA; Raymond, Daniel P DP; Murthy, Sudish C SC; Ahmad, Usman U; Raja, Siva S; Almeida, Francisco F; Sethi, Sonali S; Gildea, Thomas R TR; Peacock, Craig D CD; Adams, Drew J DJ; Abazeed, Mohamed E ME

Publication Date: 2019-11-13

Variant appearance in text: BRAF: L597V

PubMed Link: 31723142

Variant Present in the following documents:

• 41467_2019_Article_13161.pdf
• 41467_2019_13161_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Targeting Oncogenic BRAF: Past, Present, and Future.

Cancers

Zaman, Aubhishek A; Wu, Wei W; Bivona, Trever G TG

Publication Date: 2019-08-16

Variant appearance in text: BRAF: L597V

PubMed Link: 31426419

Variant Present in the following documents:

• Main text
• cancers-11-01197.pdf

View BVdb publication page

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Atypical BRAF and NRAS Mutations in Mucosal Melanoma.

Cancers

Dumaz, Nicolas N; Jouenne, Fanélie F; Delyon, Julie J; Mourah, Samia S; Bensussan, Armand A; Lebbé, Céleste C

Publication Date: 2019-08-08

Variant appearance in text: BRAF: L597V

PubMed Link: 31398831

Variant Present in the following documents:

• Main text
• cancers-11-01133.pdf

View BVdb publication page

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Rare, functional, somatic variants in gene families linked to cancer genes: GPCR signaling as a paradigm.

Oncogene

Raimondi, Francesco F; Inoue, Asuka A; Kadji, Francois M N FMN; Shuai, Ni N; Gonzalez, Juan-Carlos JC; Singh, Gurdeep G; de la Vega, Alicia Alonso AA; Sotillo, Rocio R; Fischer, Bernd B; Aoki, Junken J; Gutkind, J Silvio JS; Russell, Robert B RB

Publication Date: 2019-09

Variant appearance in text: BRAF: L597V

PubMed Link: 31337866

Variant Present in the following documents:

• 41388_2019_895_MOESM2_ESM.xlsx, sheet 8

View BVdb publication page

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