Publications:

---

Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: EGFR: P596L

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 4
• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 3
• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 2
• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 3
• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2

View BVdb publication page

---

Genetic testing and prognosis of sarcomatoid hepatocellular carcinoma patients.

Frontiers In Oncology

Jia, Bin B; Xia, Peiyi P; Dong, Junqiang J; Feng, Wenhao W; Wang, Wenjia W; Liu, Enjie E; Jiang, Guozhong G; Qin, Yanru Y

Publication Date: 2022

Variant appearance in text: EGFR: P596L

PubMed Link: 36741696

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Impact of EGFRA289T/V mutation on relapse pattern in glioblastoma.

Esmo Open

Noeuveglise, A A; Sarafan-Vasseur, N N; Beaussire, L L; Marguet, F F; Modzelewski, R R; Hanzen, C C; Alexandru, C C; Magne, N N; Langlois, O O; Di Fiore, F F; Clatot, F F; Thureau, S S; Fontanilles, M M

Publication Date: 2022-12-22

Variant appearance in text: EGFR: P596L

PubMed Link: 36566697

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

---

Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: EGFR: P596L

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 4
• Table3.xlsx, sheet 1

View BVdb publication page

---

Clinical utility of liquid biopsy and integrative genomic profiling in early-stage and oligometastatic cancer patients treated with radiotherapy.

British Journal Of Cancer

Cifuentes, Guadalupe A GA; Santiago, Adrián A; Méndez Blanco, Lucía L; Fueyo, María M; López Martínez, Esther E; Soria, Raquel R; Martín López, Irene I; Cucarella Beltrán, Pepa P; Pardo-Coto, Pablo P; Rodriguez-Rubi, David D; Urquilla, Karla K; Durán, Noelia S NS; Álvarez, Rebeca R; Lago, Claudia G CG; Otero, Andrea A; Diñeiro, Marta M; Capín, Raquel R; Cadiñanos, Juan J; Cabanillas, Rubén R

Publication Date: 2022-12-22

Variant appearance in text: EGFR: 1787C>T; Pro596Leu

PubMed Link: 36550207

Variant Present in the following documents:

• Main text
• 41416_2022_2102_MOESM6_ESM.xlsx, sheet 1
• 41416_2022_Article_2102.pdf

View BVdb publication page

---

Calibration of computational tools for missense variant pathogenicity classification and ClinGen recommendations for PP3/BP4 criteria.

American Journal Of Human Genetics

Pejaver, Vikas V; Byrne, Alicia B AB; Feng, Bing-Jian BJ; Pagel, Kymberleigh A KA; Mooney, Sean D SD; Karchin, Rachel R; O'Donnell-Luria, Anne A; Harrison, Steven M SM; Tavtigian, Sean V SV; Greenblatt, Marc S MS; Biesecker, Leslie G LG; Radivojac, Predrag P; Brenner, Steven E SE; ,

Publication Date: 2022-12-01

Variant appearance in text: EGFR: P596L; rs1477025000

PubMed Link: 36413997

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

View BVdb publication page

---

L718Q/V mutation in exon 18 of EGFR mediates resistance to osimertinib: clinical features and treatment.

Discover. Oncology

Li, Meihui M; Qin, Jing J; Xie, Fajun F; Gong, Lei L; Han, Na N; Lu, Hongyang H

Publication Date: 2022-08-09

Variant appearance in text: EGFR: P596L

PubMed Link: 35943592

Variant Present in the following documents:

• Main text
• 12672_2022_Article_537.pdf

View BVdb publication page

---

Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: EGFR: P596L

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

---

Genomic Analysis of Tumors from Patients with Glioblastoma with Long-Term Response to Afatinib.

Oncotargets And Therapy

Owen, Scott S; Alken, Scheryll S; Alshami, Jad J; Guiot, Marie-Christine MC; Kavan, Petr P; Reardon, David A DA; Muanza, Thierry T; Gibson, Neil N; Pemberton, Karine K; Solca, Flavio F; Cseh, Agnieszka A; Saran, Frank F

Publication Date: 2022

Variant appearance in text: EGFR: 1787C>T; P596L

PubMed Link: 35422631

Variant Present in the following documents:

• Main text
• ott-15-367.pdf

View BVdb publication page

---

Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: P596L

PubMed Link: 35304574

Variant Present in the following documents:

• 41388_2022_Article_2263.pdf

View BVdb publication page

---

Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.

Nature Biotechnology

Sánchez-Rivera, Francisco J FJ; Diaz, Bianca J BJ; Kastenhuber, Edward R ER; Schmidt, Henri H; Katti, Alyna A; Kennedy, Margaret M; Tem, Vincent V; Ho, Yu-Jui YJ; Leibold, Josef J; Paffenholz, Stella V SV; Barriga, Francisco M FM; Chu, Kevan K; Goswami, Sukanya S; Wuest, Alexandra N AN; Simon, Janelle M JM; Tsanov, Kaloyan M KM; Chakravarty, Debyani D; Zhang, Hongxin H; Leslie, Christina S CS; Lowe, Scott W SW; Dow, Lukas E LE

Publication Date: 2022-06

Variant appearance in text: EGFR: P596L

PubMed Link: 35165384

Variant Present in the following documents:

• NIHMS1760571-supplement-Supplementary_Table_S2.xlsx, sheet 6
• NIHMS1760571-supplement-Supplementary_Table_S7.xlsx, sheet 5
• NIHMS1760571-supplement-Supplementary_Table_S2.xlsx, sheet 4

View BVdb publication page

---

Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (Cambridge (Mass.))

Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J

Publication Date: 2021-05-28

Variant appearance in text: EGFR: P596L

PubMed Link: 34557754

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

---

Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (New York, N.Y.)

Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J

Publication Date: 2021-05-28

Variant appearance in text: EGFR: P596L

PubMed Link: 34557754

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

---

Nivolumab Plus Ipilimumab vs Nivolumab for Previously Treated Patients With Stage IV Squamous Cell Lung Cancer: The Lung-MAP S1400I Phase 3 Randomized Clinical Trial.

Jama Oncology

Gettinger, Scott N SN; Redman, Mary W MW; Bazhenova, Lyudmila L; Hirsch, Fred R FR; Mack, Philip C PC; Schwartz, Lawrence H LH; Bradley, Jeffrey D JD; Stinchcombe, Thomas E TE; Leighl, Natasha B NB; Ramalingam, Suresh S SS; Tavernier, Susan S SS; Yu, Hui H; Unger, Joseph M JM; Minichiello, Katherine K; Highleyman, Louise L; Papadimitrakopoulou, Vassiliki A VA; Kelly, Karen K; Gandara, David R DR; Herbst, Roy S RS

Publication Date: 2021-09-01

Variant appearance in text: EGFR: P596L

PubMed Link: 34264316

Variant Present in the following documents:

• jamaoncol-e212209-s002.pdf
• jamaoncol-e212209-s001.pdf

View BVdb publication page

---

Comprehensive molecular profiling of pulmonary pleomorphic carcinoma.

Npj Precision Oncology

Nagano, Masaaki M; Kohsaka, Shinji S; Hayashi, Takuo T; Ueno, Toshihide T; Kojima, Shinya S; Shinozaki-Ushiku, Aya A; Morita, Shigeki S; Tsuda, Masumi M; Tanaka, Shinya S; Shinohara, Toshiya T; Omori, Yuko Y; Sugaya, Fumiko F; Kato, Hiroaki H; Narita, Yoshiaki Y; Nakajima, Jun J; Suzuki, Kenji K; Takamochi, Kazuya K; Mano, Hiroyuki H

Publication Date: 2021-06-22

Variant appearance in text: EGFR: 1787C>T; Pro596Leu

PubMed Link: 34158601

Variant Present in the following documents:

• 41698_2021_201_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: EGFR: 1787C>T; P596L

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

---

A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement.

Nature Communications

Zhang, Yiqun Y; Chen, Fengju F; Donehower, Lawrence A LA; Scheurer, Michael E ME; Creighton, Chad J CJ

Publication Date: 2021-02-10

Variant appearance in text: EGFR: 1787C>T; P596L; rs1477025000

PubMed Link: 33568653

Variant Present in the following documents:

• 41467_2021_21081_MOESM8_ESM.xlsx, sheet 3

View BVdb publication page

---

Targeted Genomic Sequencing Reveals Different Evolutionary Patterns Between Locally and Distally Recurrent Glioblastomas.

Cancer Genomics & Proteomics

Yoon, Nara N; Kim, Hyun-Soo HS; Lee, Jung Whee JW; Lee, Eui-Jin EJ; Maeng, Lee-So LS; Yoon, Wan Soo WS

Publication Date: 2020

Variant appearance in text: EGFR: Pro596Leu

PubMed Link: 33099481

Variant Present in the following documents:

• Main text

View BVdb publication page

---

TP53, ATRX alterations, and low tumor mutation load feature IDH-wildtype giant cell glioblastoma despite exceptional ultra-mutated tumors.

Neuro-Oncology Advances

Cantero, Diana D; Mollejo, Manuela M; Sepúlveda, Juan M JM; D'Haene, Nicky N; Gutiérrez-Guamán, Myriam J MJ; Rodríguez de Lope, Ángel Á; Fiaño, Concepción C; Castresana, Javier S JS; Lebrun, Laetitia L; Rey, Juan A JA; Salmon, Isabelle I; Meléndez, Bárbara B; Hernández-Laín, Aurelio A

Publication Date: 2020

Variant appearance in text: EGFR: 1787C>T; Pro596Leu

PubMed Link: 32642724

Variant Present in the following documents:

• vdz059_suppl_suplementary_table_2.xlsx, sheet 1

View BVdb publication page

---

Phase and context shape the function of composite oncogenic mutations.

Nature

Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS

Publication Date: 2020-06

Variant appearance in text: EGFR: P596L

PubMed Link: 32461694

Variant Present in the following documents:

• NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx, sheet 2

View BVdb publication page

---

A large peptidome dataset improves HLA class I epitope prediction across most of the human population.

Nature Biotechnology

Sarkizova, Siranush S; Klaeger, Susan S; Le, Phuong M PM; Li, Letitia W LW; Oliveira, Giacomo G; Keshishian, Hasmik H; Hartigan, Christina R CR; Zhang, Wandi W; Braun, David A DA; Ligon, Keith L KL; Bachireddy, Pavan P; Zervantonakis, Ioannis K IK; Rosenbluth, Jennifer M JM; Ouspenskaia, Tamara T; Law, Travis T; Justesen, Sune S; Stevens, Jonathan J; Lane, William J WJ; Eisenhaure, Thomas T; Lan Zhang, Guang G; Clauser, Karl R KR; Hacohen, Nir N; Carr, Steven A SA; Wu, Catherine J CJ; Keskin, Derin B DB

Publication Date: 2020-02

Variant appearance in text: EGFR: P596L

PubMed Link: 31844290

Variant Present in the following documents:

• NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 12
• NIHMS1541512-supplement-Sup_Data2.xlsx, sheet 5

View BVdb publication page

---

Survival of diffuse astrocytic glioma, IDH1/2 wildtype, with molecular features of glioblastoma, WHO grade IV: a confirmation of the cIMPACT-NOW criteria.

Neuro-Oncology

Tesileanu, C Mircea S CMS; Dirven, Linda L; Wijnenga, Maarten M J MMJ; Koekkoek, Johan A F JAF; Vincent, Arnaud J P E AJPE; Dubbink, Hendrikus J HJ; Atmodimedjo, Peggy N PN; Kros, Johan M JM; van Duinen, Sjoerd G SG; Smits, Marion M; Taphoorn, Martin J B MJB; French, Pim J PJ; van den Bent, Martin J MJ

Publication Date: 2020-04-15

Variant appearance in text: EGFR: P596L

PubMed Link: 31637414

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Systematic analysis of the intersection of disease mutations with protein modifications.

Bmc Medical Genomics

Simpson, Claire M CM; Zhang, Bin B; Hornbeck, Peter V PV; Gnad, Florian F

Publication Date: 2019-07-25

Variant appearance in text: EGFR: P596L

PubMed Link: 31345222

Variant Present in the following documents:

• 12920_2019_543_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: EGFR: P596L

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

View BVdb publication page

---

Targeted mutation detection in breast cancer using MammaSeq™.

Breast Cancer Research : Bcr

Smith, Nicholas G NG; Gyanchandani, Rekha R; Shah, Osama S OS; Gurda, Grzegorz T GT; Lucas, Peter C PC; Hartmaier, Ryan J RJ; Brufsky, Adam M AM; Puhalla, Shannon S; Bahreini, Amir A; Kota, Karthik K; Wald, Abigail I AI; Nikiforov, Yuri E YE; Nikiforova, Marina N MN; Oesterreich, Steffi S; Lee, Adrian V AV

Publication Date: 2019-02-08

Variant appearance in text: EGFR: P596L

PubMed Link: 30736836

Variant Present in the following documents:

• 13058_2019_1102_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

Integrative omics analyses broaden treatment targets in human cancer.

Genome Medicine

Sengupta, Sohini S; Sun, Sam Q SQ; Huang, Kuan-Lin KL; Oh, Clara C; Bailey, Matthew H MH; Varghese, Rajees R; Wyczalkowski, Matthew A MA; Ning, Jie J; Tripathi, Piyush P; McMichael, Joshua F JF; Johnson, Kimberly J KJ; Kandoth, Cyriac C; Welch, John J; Ma, Cynthia C; Wendl, Michael C MC; Payne, Samuel H SH; Fenyö, David D; Townsend, Reid R RR; Dipersio, John F JF; Chen, Feng F; Ding, Li L

Publication Date: 2018-07-27

Variant appearance in text: EGFR: P596L

PubMed Link: 30053901

Variant Present in the following documents:

• 13073_2018_564_MOESM2_ESM.xlsx, sheet 19
• 13073_2018_564_MOESM2_ESM.xlsx, sheet 13

View BVdb publication page

---

Heterogeneous responses and resistant mechanisms to crizotinib in ALK-positive advanced non-small cell lung cancer.

Thoracic Cancer

Kang, Jin J; Chen, Hua-Jun HJ; Zhang, Xu-Chao XC; Su, Jian J; Zhou, Qing Q; Tu, Hai-Yan HY; Wang, Zhen Z; Wang, Bin-Chao BC; Zhong, Wen-Zhao WZ; Yang, Xue-Ning XN; Chen, Zhi-Hong ZH; Ding, Yan Y; Wu, Xue X; Wang, Mei M; Fu, Jian-Gang JG; Yang, Zhenfan Z; Zhang, Xian X; Shao, Yang W YW; Wu, Yi-Long YL; Yang, Jin-Ji JJ

Publication Date: 2018-09

Variant appearance in text: EGFR: P596L

PubMed Link: 29978950

Variant Present in the following documents:

• Main text
• TCA-9-1093-s006.xlsx, sheet 1
• TCA-9-1093.pdf

View BVdb publication page

---

The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection.

Oncotarget

Muscat, Andrea M AM; Wong, Nicholas C NC; Drummond, Katharine J KJ; Algar, Elizabeth M EM; Khasraw, Mustafa M; Verhaak, Roel R; Field, Kathryn K; Rosenthal, Mark A MA; Ashley, David M DM

Publication Date: 2018-01-30

Variant appearance in text: EGFR: 1787C>T; Pro596Leu

PubMed Link: 29487696

Variant Present in the following documents:

• oncotarget-09-7844-s003.xlsx, sheet 1

View BVdb publication page

---

Mechanisms of receptor tyrosine kinase activation in cancer.

Molecular Cancer

Du, Zhenfang Z; Lovly, Christine M CM

Publication Date: 2018-02-19

Variant appearance in text: EGFR: P596L

PubMed Link: 29455648

Variant Present in the following documents:

• Main text
• 12943_2018_Article_782.pdf

View BVdb publication page

---

Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates.

Gut

Sievers, Chelsie K CK; Zou, Luli S LS; Pickhardt, Perry J PJ; Matkowskyj, Kristina A KA; Albrecht, Dawn M DM; Clipson, Linda L; Bacher, Jeffery W JW; Pooler, B Dustin BD; Moawad, Fouad J FJ; Cash, Brooks D BD; Reichelderfer, Mark M; Vo, Tien N TN; Newton, Michael A MA; Larget, Bret R BR; Halberg, Richard B RB

Publication Date: 2017-12

Variant appearance in text: EGFR: P596L

PubMed Link: 27609830

Variant Present in the following documents:

• gutjnl-2016-312232supp002.pdf

View BVdb publication page

---

REGene: a literature-based knowledgebase of animal regeneration that bridge tissue regeneration and cancer.

Scientific Reports

Zhao, Min M; Rotgans, Bronwyn B; Wang, Tianfang T; Cummins, S F SF

Publication Date: 2016-03-15

Variant appearance in text: EGFR: P596L

PubMed Link: 26975833

Variant Present in the following documents:

• srep23167-s9.xls, sheet 1

View BVdb publication page

---

Functional annotation of rare gene aberration drivers of pancreatic cancer.

Nature Communications

Tsang, Yiu Huen YH; Dogruluk, Turgut T; Tedeschi, Philip M PM; Wardwell-Ozgo, Joanna J; Lu, Hengyu H; Espitia, Maribel M; Nair, Nikitha N; Minelli, Rosalba R; Chong, Zechen Z; Chen, Fengju F; Chang, Qing Edward QE; Dennison, Jennifer B JB; Dogruluk, Armel A; Li, Min M; Ying, Haoqiang H; Bertino, Joseph R JR; Gingras, Marie-Claude MC; Ittmann, Michael M; Kerrigan, John J; Chen, Ken K; Creighton, Chad J CJ; Eterovic, Karina K; Mills, Gordon B GB; Scott, Kenneth L KL

Publication Date: 2016-01-25

Variant appearance in text: EGFR: P596L

PubMed Link: 26806015

Variant Present in the following documents:

• ncomms10500-s2.xls, sheet 1

View BVdb publication page

---

Afatinib, an irreversible ErbB family blocker, with protracted temozolomide in recurrent glioblastoma: a case report.

Oncotarget

Alshami, Jad J; Guiot, Marie-Christine MC; Owen, Scott S; Kavan, Petr P; Gibson, Neil N; Solca, Flavio F; Cseh, Agnieszka A; Reardon, David A DA; Muanza, Thierry T

Publication Date: 2015-10-20

Variant appearance in text: EGFR: 1787C>T; P596L

PubMed Link: 26423602

Variant Present in the following documents:

• Main text
• oncotarget-06-34030.pdf

View BVdb publication page

---

Comprehensive Genomic Profiling of Advanced Esophageal Squamous Cell Carcinomas and Esophageal Adenocarcinomas Reveals Similarities and Differences.

The Oncologist

Wang, Kai K; Johnson, Adrienne A; Ali, Siraj M SM; Klempner, Samuel J SJ; Bekaii-Saab, Tanios T; Vacirca, Jeffrey L JL; Khaira, Depinder D; Yelensky, Roman R; Chmielecki, Juliann J; Elvin, Julia A JA; Lipson, Doron D; Miller, Vincent A VA; Stephens, Philip J PJ; Ross, Jeffrey S JS

Publication Date: 2015-10

Variant appearance in text: EGFR: P596L

PubMed Link: 26336083

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Gene mutation profiling of primary glioblastoma through multiple tumor biopsy guided by 1H-magnetic resonance spectroscopy.

International Journal Of Clinical And Experimental Pathology

Tang, Chao C; Guo, Jun J; Chen, Hong H; Yao, Cheng-Jun CJ; Zhuang, Dong-Xiao DX; Wang, Yin Y; Tang, Wei-Jun WJ; Ren, Guang G; Yao, Yu Y; Wu, Jin-Song JS; Mao, Ying Y; Zhou, Liang-Fu LF

Publication Date: 2015

Variant appearance in text: EGFR: PRO596LEU

PubMed Link: 26191234

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Protein domain-level landscape of cancer-type-specific somatic mutations.

Plos Computational Biology

Yang, Fan F; Petsalaki, Evangelia E; Rolland, Thomas T; Hill, David E DE; Vidal, Marc M; Roth, Frederick P FP

Publication Date: 2015-03

Variant appearance in text: EGFR: P596L

PubMed Link: 25794154

Variant Present in the following documents:

• pcbi.1004147.s001.xlsx, sheet 1

View BVdb publication page

---

Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: EGFR: P596L

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

Age-related mutations associated with clonal hematopoietic expansion and malignancies.

Nature Medicine

Xie, Mingchao M; Lu, Charles C; Wang, Jiayin J; McLellan, Michael D MD; Johnson, Kimberly J KJ; Wendl, Michael C MC; McMichael, Joshua F JF; Schmidt, Heather K HK; Yellapantula, Venkata V; Miller, Christopher A CA; Ozenberger, Bradley A BA; Welch, John S JS; Link, Daniel C DC; Walter, Matthew J MJ; Mardis, Elaine R ER; Dipersio, John F JF; Chen, Feng F; Wilson, Richard K RK; Ley, Timothy J TJ; Ding, Li L

Publication Date: 2014-12

Variant appearance in text: EGFR: P596L

PubMed Link: 25326804

Variant Present in the following documents:

• NIHMS630249-supplement-5.xlsx, sheet 1

View BVdb publication page

---

Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas.

Acta Neuropathologica

Fontebasso, Adam M AM; Schwartzentruber, Jeremy J; Khuong-Quang, Dong-Anh DA; Liu, Xiao-Yang XY; Sturm, Dominik D; Korshunov, Andrey A; Jones, David T W DT; Witt, Hendrik H; Kool, Marcel M; Albrecht, Steffen S; Fleming, Adam A; Hadjadj, Djihad D; Busche, Stephan S; Lepage, Pierre P; Montpetit, Alexandre A; Staffa, Alfredo A; Gerges, Noha N; Zakrzewska, Magdalena M; Zakrzewski, Krzystof K; Liberski, Pawel P PP; Hauser, Peter P; Garami, Miklos M; Klekner, Almos A; Bognar, Laszlo L; Zadeh, Gelareh G; Faury, Damien D; Pfister, Stefan M SM; Jabado, Nada N; Majewski, Jacek J

Publication Date: 2013-05

Variant appearance in text: EGFR: P596L

PubMed Link: 23417712

Variant Present in the following documents:

• 401_2013_1095_MOESM1_ESM.pdf

View BVdb publication page

---

Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research

Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C

Publication Date: 2011-09-01

Variant appearance in text: EGFR: P596L

PubMed Link: 21727090

Variant Present in the following documents:

• supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1

View BVdb publication page

---

A growing family: adding mutated Erbb4 as a novel cancer target.

Cell Cycle (Georgetown, Tex.)

Rudloff, Udo U; Samuels, Yardena Y

Publication Date: 2010-04-15

Variant appearance in text: EGFR: P596L

PubMed Link: 20404484

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Mutational activation of ErbB family receptor tyrosine kinases: insights into mechanisms of signal transduction and tumorigenesis.

Bioessays : News And Reviews In Molecular, Cellular And Developmental Biology

Riese, David J DJ; Gallo, Richard M RM; Settleman, Jeffrey J

Publication Date: 2007-06

Variant appearance in text: EGFR: P596L

PubMed Link: 17508401

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.

Plos Medicine

Lee, Jeffrey C JC; Vivanco, Igor I; Beroukhim, Rameen R; Huang, Julie H Y JH; Feng, Whei L WL; DeBiasi, Ralph M RM; Yoshimoto, Koji K; King, Jennifer C JC; Nghiemphu, Phioanh P; Yuza, Yuki Y; Xu, Qing Q; Greulich, Heidi H; Thomas, Roman K RK; Paez, J Guillermo JG; Peck, Timothy C TC; Linhart, David J DJ; Glatt, Karen A KA; Getz, Gad G; Onofrio, Robert R; Ziaugra, Liuda L; Levine, Ross L RL; Gabriel, Stacey S; Kawaguchi, Tomohiro T; O'Neill, Keith K; Khan, Haumith H; Liau, Linda M LM; Nelson, Stanley F SF; Rao, P Nagesh PN; Mischel, Paul P; Pieper, Russell O RO; Cloughesy, Tim T; Leahy, Daniel J DJ; Sellers, William R WR; Sawyers, Charles L CL; Meyerson, Matthew M; Mellinghoff, Ingo K IK

Publication Date: 2006-12

Variant appearance in text: EGFR: P596L

PubMed Link: 17177598

Variant Present in the following documents:

• Main text
• pmed.0030485.pdf
• pmed.0030485.sg001.pdf

View BVdb publication page

---