Publications:

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EGFR p.V774M/p.L833V compound mutations in lung adenocarcinoma responded well to almonertinib: a case report.

Frontiers In Oncology

Pan, Hai H; Zhang, Linlin L; Meng, Fanlu F; Guan, Shasha S; Zhong, Diansheng D

Publication Date: 2023

Variant appearance in text: EGFR: H773L

PubMed Link: 37251951

Variant Present in the following documents:

• Main text
• fonc-13-1159308.pdf

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Uncommon EGFR-Mutant NSCLC-One Drug Does Not Fit All.

Jto Clinical And Research Reports

Wang, Yang Y; Arulananda, Surein S

Publication Date: 2023-04

Variant appearance in text: EGFR: H773L

PubMed Link: 36994309

Variant Present in the following documents:

• Main text
• main.pdf

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Osimertinib in NSCLC With Atypical EGFR-Activating Mutations: A Retrospective Multicenter Study.

Jto Clinical And Research Reports

Ji, Jingran J; Aredo, Jacqueline V JV; Piper-Vallillo, Andrew A; Huppert, Laura L; Rotow, Julia K JK; Husain, Hatim H; Stewart, Susan S; Cobb, Rosemary R; Wakelee, Heather A HA; Blakely, Collin M CM; Wong, Melisa L ML; Gubens, Matthew A MA; Madani, Mohammad H MH; Digumarthy, Subba R SR; McCoach, Caroline C; Piotrowska, Zofia Z; Neal, Joel W JW; Riess, Jonathan W JW

Publication Date: 2023-03

Variant appearance in text: EGFR: H773L

PubMed Link: 36879929

Variant Present in the following documents:

• main.pdf

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: EGFR: 2318A>T; H773L

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 2

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Landscape of EGFR mutations in lung adenocarcinoma: a single institute experience with comparison of PANAMutyper testing and targeted next-generation sequencing.

Journal Of Pathology And Translational Medicine

Lee, Jeonghyo J; Han, Yeon Bi YB; Kwon, Hyun Jung HJ; Lee, Song Kook SK; Kim, Hyojin H; Chung, Jin-Haeng JH

Publication Date: 2022-09

Variant appearance in text: EGFR: 2318A>T; H773L

PubMed Link: 36128861

Variant Present in the following documents:

• jptm-2022-06-11-suppl1.pdf

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Insensitivity to T790M mutation? A pooled analysis of outcomes following osimertinib for the treatment of NSCLC patients harboring uncommon epidermal growth factor receptor mutation.

Frontiers In Pharmacology

Hu, Shanliang S; Wang, Congjie C; Wang, Chunsheng C; Zhao, Kewei K; Wang, Zhen Z; Dong, Wei W

Publication Date: 2022

Variant appearance in text: EGFR: H773L

PubMed Link: 36091840

Variant Present in the following documents:

• Main text
• fphar-13-986962.pdf

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: EGFR: 2318A>T; H773L

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society

Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW

Publication Date: 2022-05-23

Variant appearance in text: EGFR: 2318A>T; His773Leu

PubMed Link: 35606799

Variant Present in the following documents:

• 41021_2022_248_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Osimertinib-Centered Therapy Against Uncommon Epidermal Growth Factor Receptor-Mutated Non-Small-Cell Lung Cancer- A Mini Review.

Frontiers In Oncology

Song, Chengyang C; Yang, Xueying X

Publication Date: 2022

Variant appearance in text: EGFR: H773L

PubMed Link: 35494059

Variant Present in the following documents:

• Main text
• fonc-12-834585.pdf

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Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: H773L

PubMed Link: 35304574

Variant Present in the following documents:

• 41388_2022_Article_2263.pdf

View BVdb publication page

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Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L

Publication Date: 2022-03-10

Variant appearance in text: EGFR: 2318A>T; H773L

PubMed Link: 35273153

Variant Present in the following documents:

• 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Identifying Actionable Variants Using Capture-Based Targeted Sequencing in 563 Patients With Non-Small Cell Lung Carcinoma.

Frontiers In Oncology

Jiang, Haiping H; Wang, Yinan Y; Xu, Hanlin H; Lei, Wei W; Yu, Xiaoyun X; Tian, Haiying H; Meng, Cong C; Wang, Xueying X; Zhao, Zicheng Z; Jin, Xiangfeng X

Publication Date: 2021

Variant appearance in text: EGFR: H773L

PubMed Link: 35186718

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: EGFR: H773L

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: His773Leu

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

View BVdb publication page

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: His773Leu

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

View BVdb publication page

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Neoantigen vaccination induces clinical and immunologic responses in non-small cell lung cancer patients harboring EGFR mutations.

Journal For Immunotherapy Of Cancer

Li, Fenge F; Deng, Ligang L; Jackson, Kyle R KR; Talukder, Amjad H AH; Katailiha, Arjun S AS; Bradley, Sherille D SD; Zou, Qingwei Q; Chen, Caixia C; Huo, Chong C; Chiu, Yulun Y; Stair, Matthew M; Feng, Weihong W; Bagaev, Aleksander A; Kotlov, Nikita N; Svekolkin, Viktor V; Ataullakhanov, Ravshan R; Miheecheva, Natalia N; Frenkel, Felix F; Wang, Yaling Y; Zhang, Minying M; Hawke, David D; Han, Ling L; Zhou, Shuo S; Zhang, Yan Y; Wang, Zhenglu Z; Decker, William K WK; Sonnemann, Heather M HM; Roszik, Jason J; Forget, Marie-Andree MA; Davies, Michael A MA; Bernatchez, Chantale C; Yee, Cassian C; Bassett, Roland R; Hwu, Patrick P; Du, Xueming X; Lizee, Gregory G

Publication Date: 2021-07

Variant appearance in text: EGFR: H773L

PubMed Link: 34244308

Variant Present in the following documents:

• Main text
• jitc-2021-002531supp004.xlsx, sheet 1
• jitc-2021-002531supp006.xlsx, sheet 1
• jitc-2021-002531supp005.xlsx, sheet 1
• jitc-2021-002531.pdf

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: EGFR: 2318A>T; H773L

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2318A>T; H773L

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Comprehensive genomic profiling of Brazilian non-small cell lung cancer patients (GBOT 0118/LACOG0418).

Thoracic Cancer

Mascarenhas, Eldsamira E; Gelatti, Ana Caroline AC; Araújo, Luiz Henrique LH; Baldotto, Clarissa C; Mathias, Clarissa C; Zukin, Mauro M; Werutsky, Gustavo G; Pacheco, Patricia P; Gomes, Rafaela R; de Castro, Gilberto G; Cordeiro de Lima, Vladmir Cláudio VC

Publication Date: 2021-03

Variant appearance in text: EGFR: H773L

PubMed Link: 33314759

Variant Present in the following documents:

• Main text
• TCA-12-580.pdf

View BVdb publication page

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Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma.

Nature Communications

Wang, Siwei S; Du, Mulong M; Zhang, Jingyuan J; Xu, Weizhang W; Yuan, Qianyu Q; Li, Ming M; Wang, Jie J; Zhu, Hongyu H; Wang, Yuzhuo Y; Wang, Cheng C; Gong, Yuhua Y; Wang, Xiaonan X; Hu, Zhibin Z; Christiani, David C DC; Xu, Lin L; Shen, Hongbing H; Yin, Rong R

Publication Date: 2020-11-27

Variant appearance in text: EGFR: 2318A>T; H773L

PubMed Link: 33247113

Variant Present in the following documents:

• 41467_2020_19855_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Poor effect of osimertinib on EGFR exon 20 insertion-positive lung adenocarcinoma: A case report.

Medicine

Inagaki, Yuji Y; Tamiya, Akihiro A; Matsuda, Yoshinobu Y; Azuma, Kouji K; Adachi, Yuichi Y; Enomoto, Takatoshi T; Kouno, Shunichi S; Taniguchi, Yoshihiko Y; Saijo, Nobuhiko N; Okishio, Kyoichi K; Atagi, Shinji S

Publication Date: 2020-10-16

Variant appearance in text: EGFR: H773L

PubMed Link: 33080698

Variant Present in the following documents:

• Main text
• medi-99-e22628.pdf

View BVdb publication page

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EGFR and BRAF mutations in inverted sinonasal papilloma - a more complex landscape?

Virchows Archiv : An International Journal Of Pathology

Zonnur, Sarah S; Erbersdobler, Andreas A; Schneider, Björn B

Publication Date: 2021-05

Variant appearance in text: EGFR: H773L

PubMed Link: 33048186

Variant Present in the following documents:

• Main text
• 428_2020_Article_2945.pdf

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The effectiveness of afatinib in patients with lung adenocarcinoma harboring complex epidermal growth factor receptor mutation.

Therapeutic Advances In Medical Oncology

Wu, Shang-Gin SG; Yu, Chong-Jen CJ; Yang, James Chih-Hsin JC; Shih, Jin-Yuan JY

Publication Date: 2020

Variant appearance in text: EGFR: H773L

PubMed Link: 32843903

Variant Present in the following documents:

• Main text
• 10.1177_1758835920946156.pdf

View BVdb publication page

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EGFR mutation status in a series of Turkish non-small cell lung cancer patients.

Biomedical Reports

Calibasi-Kocal, Gizem G; Amirfallah, Arsalan A; Sever, Tolga T; Umit Unal, Olcun O; Gurel, Duygu D; Oztop, Ilhan I; Ellidokuz, Hulya H; Basbinar, Yasemin Y

Publication Date: 2020-08

Variant appearance in text: EGFR: His773Leu

PubMed Link: 32509305

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: EGFR: H773L

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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Survival Disparities in Black Patients With EGFR-mutated Non-small-cell Lung Cancer.

Clinical Lung Cancer

Cheng, Haiying H; Hosgood, H Dean HD; Deng, Lei L; Ye, Kenny K; Su, Christopher C; Sharma, Janaki J; Yang, Yuanquan Y; Halmos, Balazs B; Perez-Soler, Roman R

Publication Date: 2020-03

Variant appearance in text: EGFR: H773L

PubMed Link: 31420240

Variant Present in the following documents:

• Main text

View BVdb publication page

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Treatment of uncommon EGFR mutations in non-small cell lung cancer: new evidence and treatment.

Translational Lung Cancer Research

Zhang, Tianli T; Wan, Bing B; Zhao, Yuan Y; Li, Chuling C; Liu, Hongbing H; Lv, Tangfeng T; Zhan, Ping P; Song, Yong Y

Publication Date: 2019-06

Variant appearance in text: EGFR: H773L

PubMed Link: 31367543

Variant Present in the following documents:

• Main text

View BVdb publication page

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EGFR exon 20 insertion mutations and response to osimertinib in non-small-cell lung cancer.

Bmc Cancer

Fang, Wenfeng W; Huang, Yihua Y; Hong, Shaodong S; Zhang, Zhonghan Z; Wang, Minghui M; Gan, Jiadi J; Wang, Wenjing W; Guo, Honglin H; Wang, Kai K; Zhang, Li L

Publication Date: 2019-06-17

Variant appearance in text: EGFR: H773L

PubMed Link: 31208370

Variant Present in the following documents:

• Main text

View BVdb publication page

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A rare epidermal growth factor receptor H773L/V774M compound mutation in advanced non-small-cell lung cancer with poor response to epidermal growth factor receptor tyrosine kinase inhibitor.

Respirology Case Reports

Chen, Lun-Che LC; Shih, Jin-Yuan JY; Yu, Chong-Jen CJ; Yang, Ching-Yao CY

Publication Date: 2019-07

Variant appearance in text: EGFR: 2318A>T; H773L

PubMed Link: 31007929

Variant Present in the following documents:

• Main text
• RCR2-7-e00425.pdf

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Better Progression-Free Survival in Elderly Patients with Stage IV Lung Adenocarcinoma Harboring Uncommon Epidermal Growth Factor Receptor Mutations Treated with the First-line Tyrosine Kinase Inhibitors.

Cancers

Tsai, Ming-Ju MJ; Hung, Jen-Yu JY; Lee, Mei-Hsuan MH; Kuo, Chia-Yu CY; Tsai, Yu-Chen YC; Tsai, Ying-Ming YM; Liu, Ta-Chih TC; Yang, Chih-Jen CJ; Huang, Ming-Shyan MS; Chong, Inn-Wen IW

Publication Date: 2018-11-13

Variant appearance in text: EGFR: H773L

PubMed Link: 30428509

Variant Present in the following documents:

• cancers-10-00434.pdf

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Mutations of the Epidermal Growth Factor Receptor Gene in Triple-Negative Breast Cancer.

Journal Of Breast Cancer

Kim, Aeri A; Jang, Min Hye MH; Lee, Soo Jung SJ; Bae, Young Kyung YK

Publication Date: 2017-06

Variant appearance in text: EGFR: H773L

PubMed Link: 28690651

Variant Present in the following documents:

• Main text

View BVdb publication page

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Significant Improvement in Detecting BRAF, KRAS, and EGFR Mutations Using Next-Generation Sequencing as Compared with FDA-Cleared Kits.

Molecular Diagnosis & Therapy

Ma, Wanlong W; Brodie, Steven S; Agersborg, Sally S; Funari, Vincent A VA; Albitar, Maher M

Publication Date: 2017-10

Variant appearance in text: EGFR: 2318A>T; His773Leu

PubMed Link: 28639239

Variant Present in the following documents:

• Main text
• 40291_2017_Article_290.pdf

View BVdb publication page

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Nexus of signaling and endocytosis in oncogenesis driven by non-small cell lung cancer-associated epidermal growth factor receptor mutants.

World Journal Of Clinical Oncology

Chung, Byung Min BM; Tom, Eric E; Zutshi, Neha N; Bielecki, Timothy Alan TA; Band, Vimla V; Band, Hamid H

Publication Date: 2014-12-10

Variant appearance in text: EGFR: H773L

PubMed Link: 25493220

Variant Present in the following documents:

• Main text

View BVdb publication page

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Increased detection rates of EGFR and KRAS mutations in NSCLC specimens with low tumour cell content by 454 deep sequencing.

Virchows Archiv : An International Journal Of Pathology

Moskalev, Evgeny A EA; Stöhr, Robert R; Rieker, Ralf R; Hebele, Simone S; Fuchs, Florian F; Sirbu, Horia H; Mastitsky, Sergey E SE; Boltze, Carsten C; König, Helmut H; Agaimy, Abbas A; Hartmann, Arndt A; Haller, Florian F

Publication Date: 2013-04

Variant appearance in text: EGFR: 2318A>T; H773L

PubMed Link: 23468066

Variant Present in the following documents:

• Main text
• 428_2013_Article_1376.pdf

View BVdb publication page

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Compound EGFR mutations and response to EGFR tyrosine kinase inhibitors.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer

Kobayashi, Susumu S; Canepa, Hannah M HM; Bailey, Alexandra S AS; Nakayama, Sohei S; Yamaguchi, Norihiro N; Goldstein, Michael A MA; Huberman, Mark S MS; Costa, Daniel B DB

Publication Date: 2013-01

Variant appearance in text: EGFR: H773L

PubMed Link: 23242437

Variant Present in the following documents:

• Main text

View BVdb publication page

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The energy landscape analysis of cancer mutations in protein kinases.

Plos One

Dixit, Anshuman A; Verkhivker, Gennady M GM

Publication Date: 2011

Variant appearance in text: EGFR: H773L

PubMed Link: 21998754

Variant Present in the following documents:

View BVdb publication page

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Acquired resistance to epidermal growth factor receptor kinase inhibitors associated with a novel T854A mutation in a patient with EGFR-mutant lung adenocarcinoma.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Bean, James J; Riely, Gregory J GJ; Balak, Marissa M; Marks, Jenifer L JL; Ladanyi, Marc M; Miller, Vincent A VA; Pao, William W

Publication Date: 2008-11-15

Variant appearance in text: EGFR: H773L

PubMed Link: 19010870

Variant Present in the following documents:

• Main text

View BVdb publication page

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Epidemiology of doublet/multiplet mutations in lung cancers: evidence that a subset arises by chronocoordinate events.

Plos One

Chen, Zhenbin Z; Feng, Jinong J; Buzin, Carolyn H CH; Sommer, Steve S SS

Publication Date: 2008

Variant appearance in text: EGFR: H773L

PubMed Link: 19005564

Variant Present in the following documents:

• pone.0003714.s003.xls, sheet 1

View BVdb publication page

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Laser capture microdissection and protein microarray analysis of human non-small cell lung cancer: differential epidermal growth factor receptor (EGPR) phosphorylation events associated with mutated EGFR compared with wild type.

Molecular & Cellular Proteomics : Mcp

VanMeter, Amy J AJ; Rodriguez, Adrianna S AS; Bowman, Elise D ED; Jen, Jin J; Harris, Curtis C CC; Deng, Jianghong J; Calvert, Valerie S VS; Silvestri, Alessandra A; Fredolini, Claudia C; Chandhoke, Vikas V; Petricoin, Emanuel F EF; Liotta, Lance A LA; Espina, Virginia V

Publication Date: 2008-10

Variant appearance in text: EGFR: H773L

PubMed Link: 18687633

Variant Present in the following documents:

• Main text

View BVdb publication page

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