Publications:

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Overview on Therapeutic Options in Uncommon EGFR Mutant Non-Small Cell Lung Cancer (NSCLC): New Lights for an Unmet Medical Need.

International Journal Of Molecular Sciences

Pretelli, Giulia G; Spagnolo, Calogera Claudia CC; Ciappina, Giuliana G; Santarpia, Mariacarmela M; Pasello, Giulia G

Publication Date: 2023-05-17

Variant appearance in text: EGFR: R776H

PubMed Link: 37240224

Variant Present in the following documents:

• Main text
• ijms-24-08878.pdf

View BVdb publication page

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Somatic mutation detection and KRAS amplification in testicular germ cell tumors.

Frontiers In Oncology

Cabral, Eduardo R M ERM; Pacanhella, Marilia F MF; Lengert, Andre V H AVH; Dos Reis, Mariana B MB; Leal, Leticia F LF; de Lima, Marcos A MA; da Silva, Aline L V ALV; Pinto, Icaro A IA; Reis, Rui M RM; Pinto, Mariana T MT; Cárcano, Flavio M FM

Publication Date: 2023

Variant appearance in text: EGFR: R776H

PubMed Link: 37007070

Variant Present in the following documents:

• Main text
• fonc-13-1133363.pdf

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: EGFR: 2327G>A; Arg776His

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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A Primary Lung and Breast Cancer Patient with Germline EGFR R776H Mutation: A Case Report and Literature Review.

Oncotargets And Therapy

Li, Dan D; Liu, Xin X; Cui, SaiQiong S; Yang, DaFu D; Zhu, Yue Y; Pan, Evenki E; Yang, Peng P; Dai, ZhaoXia Z

Publication Date: 2023

Variant appearance in text: EGFR: R776H

PubMed Link: 36698436

Variant Present in the following documents:

• Main text
• ott-16-17.pdf

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: rs483352806

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 4

View BVdb publication page

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: EGFR: 2327G>A; R776H

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 3
• Table_2.xlsx, sheet 2

View BVdb publication page

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Inconsistent clinical outcomes following afatinib treatment in NSCLC patients harboring uncommon epidermal growth factor receptor mutation.

Frontiers In Oncology

Dong, Wei W; Wang, Congjie C; Wang, Chunsheng C; Zhao, Kewei K; Ma, Zhao Z; Hu, Shanliang S

Publication Date: 2022

Variant appearance in text: EGFR: R776H

PubMed Link: 36425553

Variant Present in the following documents:

• DataSheet_1.pdf

View BVdb publication page

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Multiple mutations in the EGFR gene in lung cancer: a systematic review.

Translational Lung Cancer Research

Castañeda-González, Juan Pablo JP; Chaves, Juan José JJ; Parra-Medina, Rafael R

Publication Date: 2022-10

Variant appearance in text: EGFR: R776H

PubMed Link: 36386461

Variant Present in the following documents:

• Main text
• tlcr-11-10-2148.pdf

View BVdb publication page

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Association of smoking status with non-small cell lung cancer patients harboring uncommon epidermal growth factor receptor mutation.

Frontiers In Immunology

Ko, How-Wen HW; Shie, Shian-Sen SS; Wang, Chih-Wei CW; Chiu, Chi-Tsun CT; Wang, Chih-Liang CL; Yang, Tsung-Ying TY; Chou, Shou-Chu SC; Liu, Chien-Ying CY; Kuo, Chih-Hsi Scott CS; Lin, Yu-Ching YC; Li, Li-Fu LF; Yang, Cheng-Ta CT; Wang, Chin-Chou CC

Publication Date: 2022

Variant appearance in text: EGFR: R776H

PubMed Link: 36341427

Variant Present in the following documents:

• Main text
• fimmu-13-1011092.pdf

View BVdb publication page

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Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin.

Cancer Research

Ho, Gwo Yaw GY; Kyran, Elizabeth L EL; Bedo, Justin J; Wakefield, Matthew J MJ; Ennis, Darren P DP; Mirza, Hasan B HB; Vandenberg, Cassandra J CJ; Lieschke, Elizabeth E; Farrell, Andrew A; Hadla, Anthony A; Lim, Ratana R; Dall, Genevieve G; Vince, James E JE; Chua, Ngee Kiat NK; Kondrashova, Olga O; Upstill-Goddard, Rosanna R; Bailey, Ulla-Maja UM; Dowson, Suzanne S; Roxburgh, Patricia P; Glasspool, Rosalind M RM; Bryson, Gareth G; Biankin, Andrew V AV; , ; Cooke, Susanna L SL; Ratnayake, Gayanie G; McNally, Orla O; Traficante, Nadia N; , ; DeFazio, Anna A; Weroha, S John SJ; Bowtell, David D DD; McNeish, Iain A IA; Papenfuss, Anthony T AT; Scott, Clare L CL; Barker, Holly E HE

Publication Date: 2022-12-02

Variant appearance in text: EGFR: 2327G>A; Arg776His

PubMed Link: 36206301

Variant Present in the following documents:

• can-21-4012_supplementary_data_suppst1-st24.xlsx, sheet 4

View BVdb publication page

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Utilization of cytologic cell blocks for targeted sequencing of solid tumors.

Cancer Medicine

Vormittag-Nocito, Erica E; Kumar, Ravindra R; Narayan, Kunwar Digvijay KD; Chen, Zhengjia Z; David, Odile O; Behm, Frederick F; Mohapatra, Gayatry G

Publication Date: 2022-09-20

Variant appearance in text: EGFR: R776H

PubMed Link: 36125633

Variant Present in the following documents:

• Main text
• CAM4-12-4042-s001.xlsx, sheet 1
• CAM4-12-4042.pdf

View BVdb publication page

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Ultrasensitive tumour-agnostic non-invasive detection of colorectal cancer recurrence using ctDNA methylation.

Clinical And Translational Medicine

Xiao, Yu Y; Wang, Xiaodong X; Weng, Hong H; Ding, Zhao Z; Qian, Kaiyu K; Jin, Wan W; Lu, Sen S; Ju, Lingao L; He, Zhiwen Z; Wang, Gang G; Xie, Xiaoyu X; Liu, Dongmei D; Fan, Zhou Z; Wu, Kai K; Li, Sheng S; Guo, Huanhuan H; Qian, Guofeng G; Jiang, Wei W; Leng, Yunji Y; Zhao, Junpeng J; Cao, Xinyue X; Peng, Minsheng M; Jiang, Congqing C; Li, Li L; Zhang, Yi Y; Wang, Xinghuan X

Publication Date: 2022-09

Variant appearance in text: EGFR: 2327G>A; R776H

PubMed Link: 36103400

Variant Present in the following documents:

• CTM2-12-e1015-s002.xlsx, sheet 1

View BVdb publication page

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Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma.

Nature Communications

Coy, Shannon S; Wang, Shu S; Stopka, Sylwia A SA; Lin, Jia-Ren JR; Yapp, Clarence C; Ritch, Cecily C CC; Salhi, Lisa L; Baker, Gregory J GJ; Rashid, Rumana R; Baquer, Gerard G; Regan, Michael M; Khadka, Prasidda P; Cole, Kristina A KA; Hwang, Jaeho J; Wen, Patrick Y PY; Bandopadhayay, Pratiti P; Santi, Mariarita M; De Raedt, Thomas T; Ligon, Keith L KL; Agar, Nathalie Y R NYR; Sorger, Peter K PK; Touat, Mehdi M; Santagata, Sandro S

Publication Date: 2022-08-16

Variant appearance in text: EGFR: R776H

PubMed Link: 35973991

Variant Present in the following documents:

• 41467_2022_32430_MOESM17_ESM.xlsx, sheet 31

View BVdb publication page

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Case Report: Durable partial response to icotinib plus crizotinib in a lung adenocarcinoma patient with double uncommon EGFR G719D/L861Q mutations and an acquired novel CUX1-MET fusion.

Frontiers In Oncology

Ou, Lanzi L; Tang, Yicong Y; Deng, Yanming Y; Guo, Lijie L; He, Qingqing Q; He, Tingting T; Feng, Weineng W

Publication Date: 2022

Variant appearance in text: EGFR: R776H

PubMed Link: 35957915

Variant Present in the following documents:

• Main text
• fonc-12-911362.pdf

View BVdb publication page

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Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology

Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J

Publication Date: 2022

Variant appearance in text: EGFR: 2327G>A; R776H

PubMed Link: 35814426

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 2

View BVdb publication page

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Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society

Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW

Publication Date: 2022-05-23

Variant appearance in text: EGFR: 2327G>A; Arg776His

PubMed Link: 35606799

Variant Present in the following documents:

• 41021_2022_248_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Plasma Genotyping at the Time of Diagnostic Tissue Biopsy Decreases Time-to-Treatment in Patients With Advanced NSCLC-Results From a Prospective Pilot Study.

Jto Clinical And Research Reports

Thompson, Jeffrey C JC; Aggarwal, Charu C; Wong, Janeline J; Nimgaonkar, Vivek V; Hwang, Wei-Ting WT; Andronov, Michelle M; Dibardino, David M DM; Hutchinson, Christoph T CT; Ma, Kevin C KC; Lanfranco, Anthony A; Moon, Edmund E; Haas, Andrew R AR; Singh, Aditi P AP; Ciunci, Christine A CA; Marmarelis, Melina M; D'Avella, Christopher C; Cohen, Justine V JV; Bauml, Joshua M JM; Cohen, Roger B RB; Langer, Corey J CJ; Vachani, Anil A; Carpenter, Erica L EL

Publication Date: 2022-04

Variant appearance in text: EGFR: R776H

PubMed Link: 35392653

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

View BVdb publication page

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Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: R776H

PubMed Link: 35304574

Variant Present in the following documents:

• 41388_2022_Article_2263.pdf

View BVdb publication page

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Tyrosine Kinase Inhibitor Activity in Patients with NSCLC Harboring Uncommon EGFR Mutations: A Retrospective International Cohort Study (UpSwinG).

The Oncologist

Popat, Sanjay S; Hsia, Te-Chun TC; Hung, Jen-Yu JY; Jung, Hyun Ae HA; Shih, Jin-Yuan JY; Park, Cheol Kyu CK; Lee, Seung Hyeun SH; Okamoto, Tatsuro T; Ahn, Hee Kyung HK; Lee, Yong Chul YC; Sato, Yuki Y; Lee, Sung Sook SS; Mascaux, Celine C; Daoud, Hasan H; Märten, Angela A; Miura, Satoru S

Publication Date: 2022-04-05

Variant appearance in text: EGFR: R776H

PubMed Link: 35274704

Variant Present in the following documents:

• Main text
• oyac022.pdf

View BVdb publication page

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Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L

Publication Date: 2022-03-10

Variant appearance in text: EGFR: 2327G>A; R776H

PubMed Link: 35273153

Variant Present in the following documents:

• 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Identifying Actionable Variants Using Capture-Based Targeted Sequencing in 563 Patients With Non-Small Cell Lung Carcinoma.

Frontiers In Oncology

Jiang, Haiping H; Wang, Yinan Y; Xu, Hanlin H; Lei, Wei W; Yu, Xiaoyun X; Tian, Haiying H; Meng, Cong C; Wang, Xueying X; Zhao, Zicheng Z; Jin, Xiangfeng X

Publication Date: 2021

Variant appearance in text: EGFR: R776H; rs483352806

PubMed Link: 35186718

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Identification of the Unique Clinical and Genetic Features of Chinese Lung Cancer Patients With EGFR Germline Mutations in a Large-Scale Retrospective Study.

Frontiers In Oncology

Lin, Xinqing X; Peng, Muyun M; Chen, Quanfang Q; Yuan, Mingming M; Chen, Rongrong R; Deng, Haiyi H; Deng, Jiaxi J; Liu, Ouqi O; Weng, Yuqing Y; Chen, Mingjiu M; Zhou, Chengzhi C

Publication Date: 2021

Variant appearance in text: EGFR: R776H

PubMed Link: 34869019

Variant Present in the following documents:

• Main text
• fonc-11-774156.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: EGFR: R776H

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Arg776His

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

View BVdb publication page

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Arg776His

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

View BVdb publication page

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Afatinib as a Potential Therapeutic Option for Patients With NSCLC With EGFR G724S.

Jto Clinical And Research Reports

Wei, Yang Y; Jiang, Benyuan B; Liu, Shulin S; Zhang, Zhonghan Z; Fang, Wenfeng W; Yang, Yunpeng Y; Li, Xin X; Zhao, Jingyi J; Zhao, Hongyun H

Publication Date: 2021-07

Variant appearance in text: EGFR: R776H

PubMed Link: 34590038

Variant Present in the following documents:

• Main text

View BVdb publication page

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Afatinib treatment response in advanced lung adenocarcinomas harboring uncommon mutations.

Thoracic Cancer

Li, Teng T; Wang, Shouzheng S; Ying, Jianming J; Wang, Yan Y; Hu, Xingsheng X; Hao, Xuezhi X; Xu, Ziyi Z; Xing, Puyuan P; Li, Junling J

Publication Date: 2021-11

Variant appearance in text: EGFR: R776H

PubMed Link: 34549528

Variant Present in the following documents:

• Main text
• TCA-12-2924.pdf

View BVdb publication page

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Afatinib treatment response in advanced lung adenocarcinomas harboring uncommon mutations.

Thoracic Cancer

Li, Teng T; Wang, Shouzheng S; Ying, Jianming J; Wang, Yan Y; Hu, Xingsheng X; Hao, Xuezhi X; Xu, Ziyi Z; Xing, Puyuan P; Li, Junling J

Publication Date: 2021-11

Variant appearance in text: EGFR: R776H

PubMed Link: 34549528

Variant Present in the following documents:

• Main text
• TCA-12-2924.pdf

View BVdb publication page

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Structure-based classification predicts drug response in EGFR-mutant NSCLC.

Nature

Robichaux, Jacqulyne P JP; Le, Xiuning X; Vijayan, R S K RSK; Hicks, J Kevin JK; Heeke, Simon S; Elamin, Yasir Y YY; Lin, Heather Y HY; Udagawa, Hibiki H; Skoulidis, Ferdinandos F; Tran, Hai H; Varghese, Susan S; He, Junqin J; Zhang, Fahao F; Nilsson, Monique B MB; Hu, Lemei L; Poteete, Alissa A; Rinsurongkawong, Waree W; Zhang, Xiaoshan X; Ren, Chenghui C; Liu, Xiaoke X; Hong, Lingzhi L; Zhang, Jianjun J; Diao, Lixia L; Madison, Russell R; Schrock, Alexa B AB; Saam, Jennifer J; Raymond, Victoria V; Fang, Bingliang B; Wang, Jing J; Ha, Min Jin MJ; Cross, Jason B JB; Gray, Jhanelle E JE; Heymach, John V JV

Publication Date: 2021-09

Variant appearance in text: EGFR: 2327G>A; R776H

PubMed Link: 34526717

Variant Present in the following documents:

• 41586_2021_3898_MOESM1_ESM.pdf

View BVdb publication page

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A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses.

Cancers

Koopman, Bart B; Cajiao Garcia, Betzabel N BN; Kuijpers, Chantal C H J CCHJ; Damhuis, Ronald A M RAM; van der Wekken, Anthonie J AJ; Groen, Harry J M HJM; Schuuring, Ed E; Willems, Stefan M SM; van Kempen, Léon C LC

Publication Date: 2021-07-20

Variant appearance in text: EGFR: R776H

PubMed Link: 34298851

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association of emergence of new mutations in circulating tumuor DNA during chemotherapy with clinical outcome in metastatic colorectal cancer.

Bmc Cancer

Jia, Ning N; Chang, Lianpeng L; Gao, Xin X; Shi, Xiaohua X; Dou, Xuelin X; Guan, Mei M; Shao, Yajuan Y; Li, Ningning N; Cheng, Yuejuan Y; Ying, Hongyan H; Sun, Zhao Z; Zhou, Yanping Y; Zhao, Lin L; Zhou, Jianfeng J; Bai, Chunmei C

Publication Date: 2021-07-22

Variant appearance in text: EGFR: 2327G>A; R776H

PubMed Link: 34294055

Variant Present in the following documents:

• 12885_2021_Article_8309.pdf

View BVdb publication page

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EGFR-Mutated Squamous Cell Lung Cancer and Its Association With Outcomes.

Frontiers In Oncology

Jin, Rui R; Peng, Ling L; Shou, Jiawei J; Wang, Jin J; Jin, Yin Y; Liang, Fei F; Zhao, Jing J; Wu, Mengmeng M; Li, Qin Q; Zhang, Bin B; Wu, Xiaoying X; Lan, Fen F; Xia, Lixia L; Yan, Junrong J; Shao, Yang Y; Stebbing, Justin J; Shen, Huahao H; Li, Wen W; Xia, Yang Y

Publication Date: 2021

Variant appearance in text: EGFR: 2327G>A; R776H

PubMed Link: 34195081

Variant Present in the following documents:

• Table_2.xlsx, sheet 2

View BVdb publication page

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Comparison of two targeted ultra-deep sequencing technologies for analysis of plasma circulating tumour DNA in endocrine-therapy-resistant breast cancer patients.

Breast Cancer Research And Treatment

Nteliopoulos, Georgios G; Page, Karen K; Hills, Allison A; Howarth, Karen K; Emmett, Warren W; Green, Emma E; Martinson, Luke J LJ; Fernadez-Garcia, Daniel D; Hastings, Robert R; Guttery, David S DS; Kenny, Laura L; Stebbing, Justin J; Cleator, Susan S; Rehman, Farah F; Gleason, Kelly L T KLT; Sanela, Andrijac A; Ion, Charlotte C; Rushton, Amelia J AJ; Rosenfeld, Nitzan N; Coombes, R Charles RC; Shaw, Jacqueline A JA

Publication Date: 2021-07

Variant appearance in text: EGFR: R776H

PubMed Link: 34097174

Variant Present in the following documents:

• 10549_2021_6220_MOESM2_ESM.xlsx, sheet 1
• 10549_2021_6220_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

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Presentation of EGFR mutations in 162 family probands with multiple primary lung cancer.

Translational Lung Cancer Research

Li, Chunxiang C; Wang, Yalong Y; Su, Kai K; Liu, Yu Y; Wang, Liyu L; Zheng, Bo B; Yan, Na N; Yuan, Dawei D; Zhang, Yanxiang Y; Xue, Liyan L; Gao, Shugeng S; He, Jie J

Publication Date: 2021-04

Variant appearance in text: EGFR: R776H

PubMed Link: 34012789

Variant Present in the following documents:

• Main text
• tlcr-10-04-1734-supplementary.pdf
• tlcr-10-04-1734.pdf

View BVdb publication page

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Profiling Oncogenic Germline Mutations in Unselected Chinese Lung Cancer Patients.

Frontiers In Oncology

Yang, Jie J; Li, Hefei H; Li, Ben B; Li, Wei W; Guo, Qiang Q; Hu, Ling L; Song, Zizheng Z; Zhou, Bin B

Publication Date: 2021

Variant appearance in text: EGFR: R776H

PubMed Link: 33898318

Variant Present in the following documents:

• Main text

View BVdb publication page

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Structural Basis for the Functional Changes by EGFR Exon 20 Insertion Mutations.

Cancers

Tamirat, Mahlet Z MZ; Kurppa, Kari J KJ; Elenius, Klaus K; Johnson, Mark S MS

Publication Date: 2021-03-05

Variant appearance in text: EGFR: R776H

PubMed Link: 33807850

Variant Present in the following documents:

• cancers-13-01120.pdf

View BVdb publication page

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Mutational landscape of multiple primary lung cancers and its correlation with non-intrinsic risk factors.

Scientific Reports

Izumi, Motohiro M; Oyanagi, Jun J; Sawa, Kenji K; Fukui, Mitsuru M; Ogawa, Koichi K; Matsumoto, Yoshiya Y; Tani, Yoko Y; Suzumura, Tomohiro T; Watanabe, Tetsuya T; Kaneda, Hiroyasu H; Mitsuoka, Shigeki S; Asai, Kazuhisa K; Ohsawa, Masahiko M; Yamamoto, Nobuyuki N; Koh, Yasuhiro Y; Kawaguchi, Tomoya T

Publication Date: 2021-03-11

Variant appearance in text: EGFR: R776H

PubMed Link: 33707471

Variant Present in the following documents:

• 41598_2021_Article_83609.pdf

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: EGFR: 2327G>A; R776H

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Efficacy of afatinib in a patient with rare EGFR (G724S/R776H) mutations and amplification in lung adenocarcinoma: A case report.

World Journal Of Clinical Cases

He, Shu-Yan SY; Lin, Qing-Feng QF; Chen, Jie J; Yu, Gui-Ping GP; Zhang, Jun-Ling JL; Shen, Dong D

Publication Date: 2021-02-26

Variant appearance in text: EGFR: R776H

PubMed Link: 33644199

Variant Present in the following documents:

• Main text

View BVdb publication page

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ARID1A genomic alterations driving microsatellite instability through somatic MLH1 methylation with response to immunotherapy in metastatic lung adenocarcinoma: a case report.

Journal Of Medical Case Reports

Durán, Mercedes M; Faull, Iris I; Lastra, Enrique E; Laes, Jean-Francois JF; Rodrigo, Ana Belén AB; Sánchez-Escribano, Ricardo R

Publication Date: 2021-02-19

Variant appearance in text: EGFR: R776H

PubMed Link: 33608032

Variant Present in the following documents:

• Main text
• 13256_2020_Article_2589.pdf

View BVdb publication page

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A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement.

Nature Communications

Zhang, Yiqun Y; Chen, Fengju F; Donehower, Lawrence A LA; Scheurer, Michael E ME; Creighton, Chad J CJ

Publication Date: 2021-02-10

Variant appearance in text: EGFR: 2327G>A; Arg776His; rs483352806

PubMed Link: 33568653

Variant Present in the following documents:

• 41467_2021_21081_MOESM8_ESM.xlsx, sheet 3

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2327G>A; R776H

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

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Comprehensive next-generation profiling of clonal hematopoiesis in cancer patients using paired tumor-blood sequencing for guiding personalized therapies.

Clinical And Translational Medicine

Li, Ziyang Z; Huang, Wensou W; Yin, Jiani C JC; Na, Chenglong C; Wu, Xue X; Shao, Yang Y; Ding, Huaxin H; Li, Jinming J

Publication Date: 2020-11

Variant appearance in text: EGFR: R776H

PubMed Link: 33252848

Variant Present in the following documents:

• Main text
• CTM2-10-e222-s004.xlsx, sheet 1
• CTM2-10-e222-s003.xlsx, sheet 1

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Impact of the generation of EGFR-TKIs administered as prior therapy on the efficacy of osimertinib in patients with non-small cell lung cancer harboring EGFR T790M mutation.

Thoracic Cancer

Miyashita, Yosuke Y; Ko, Ryo R; Shimada, Naoko N; Mitsuishi, Yoichiro Y; Miura, Keita K; Matsumoto, Naohisa N; Asao, Tetsuhiko T; Shukuya, Takehito T; Shibayama, Rina R; Koyama, Ryo R; Takahashi, Kazuhisa K

Publication Date: 2021-02

Variant appearance in text: EGFR: R776H

PubMed Link: 33219754

Variant Present in the following documents:

• Main text
• TCA-12-329.pdf

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Does neoadjuvant targeted therapy provide an opportunity for resectable EGFR-mutant lung cancer: a real-world retrospective study.

Journal Of Thoracic Disease

Lv, Chao C; Ma, Yuanyuan Y; Feng, Qin Q; Lu, Fangliang F; Chi, Yongkun Y; Wu, Nan N; Fang, Jian J; Yang, Yue Y

Publication Date: 2020-10

Variant appearance in text: EGFR: R776H

PubMed Link: 33209366

Variant Present in the following documents:

• Main text

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Intracellular pH Regulates Cancer and Stem Cell Behaviors: A Protein Dynamics Perspective.

Frontiers In Oncology

Liu, Yi Y; White, Katharine A KA; Barber, Diane L DL

Publication Date: 2020

Variant appearance in text: EGFR: R776H

PubMed Link: 32983969

Variant Present in the following documents:

• Main text

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Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports

Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA

Publication Date: 2020-09-21

Variant appearance in text: EGFR: R776H

PubMed Link: 32958805

Variant Present in the following documents:

• 41598_2020_72404_MOESM2_ESM.xlsx, sheet 3

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Novel EGFR V834L Germline Mutation Associated With Familial Lung Adenocarcinoma.

Jco Precision Oncology

van der Leest, Cor C; Wagner, Anja A; Pedrosa, Rute M RM; Aerts, Joachim G JG; Dinjens, Winand N M WNM; Dubbink, Hendrikus J HJ

Publication Date: 2018

Variant appearance in text: EGFR: R776H

PubMed Link: 32913987

Variant Present in the following documents:

• Main text
• PO.17.00266.pdf

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Ultra-Deep Massive Parallel Sequencing of Plasma Cell-Free DNA Enables Large-Scale Profiling of Driver Mutations in Vietnamese Patients With Advanced Non-Small Cell Lung Cancer.

Frontiers In Oncology

Tran, Le Son LS; Nguyen, Quynh-Tho Thi QT; Nguyen, Chu Van CV; Tran, Vu-Uyen VU; Nguyen, Thai-Hoa Thi TT; Le, Ha Thu HT; Nguyen, Mai-Lan Thi MT; Le, Vu Thuong VT; Pham, Lam-Son LS; Vo, Binh Thanh BT; Dang, Anh-Thu Huynh AH; Nguyen, Luan Thanh LT; Nguyen, Thien-Chi Van TV; Pham, Hong-Anh Thi HT; Tran, Thanh-Truong TT; Nguyen, Long Hung LH; Nguyen, Thanh-Thanh Thi TT; Nguyen, Kim-Huong Thi KT; Vu, Yen-Vi YV; Nguyen, Nguyen Huu NH; Bui, Vinh-Quang VQ; Bui, Hai-Ha HH; Do, Thanh-Thuy Thi TT; Lam, Nien Vinh NV; Truong Dinh, Kiet K; Phan, Minh-Duy MD; Nguyen, Hoai-Nghia HN; Giang, Hoa H

Publication Date: 2020

Variant appearance in text: EGFR: R776H

PubMed Link: 32850431

Variant Present in the following documents:

• Main text
• Table_2.xlsx, sheet 1

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The effectiveness of afatinib in patients with lung adenocarcinoma harboring complex epidermal growth factor receptor mutation.

Therapeutic Advances In Medical Oncology

Wu, Shang-Gin SG; Yu, Chong-Jen CJ; Yang, James Chih-Hsin JC; Shih, Jin-Yuan JY

Publication Date: 2020

Variant appearance in text: EGFR: R776H

PubMed Link: 32843903

Variant Present in the following documents:

• Main text
• 10.1177_1758835920946156.pdf

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